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上海交通大学医学院研究生导师简介 张雁云

上海交通大学 免费考研网/2013-01-09

基本信息
导师姓名: 张雁云 专业代码: 100102
性别: 专业名称: 免疫学
培养单位: 基础医学院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: yyzhang@sibs.ac.cn 上海市重庆南路227号上海交通大学医学院上海市免疫学研究所\邮编200025\021-63852705\yyzhang@sibs.ac.cn
研究方向 (点击浏览详细信息)
干细胞免疫学
疾病与免疫微环境
免疫生物学治疗新策略
社会任职
中国免疫学学会理事
美国免疫学学会会员
美国血液学学会会员
美国免疫学学会会员
《现代免疫学》期刊主编
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
81130057间充质干细胞治疗肝衰竭的细胞与分子机制研究国家自然科学基金重点项目2012-01~~2016-12240万元课题负责人
11JC1411400诱导抑制性树突状细胞干预多发性硬化的机制及新策略上海市科委基础研究重点项目2012-01~~2014-1250万元课题负责人
11431920900利尿钠肽等心衰治疗药物的研究上海市科委重点科技攻关2011-11~~2014-0980万元课题负责人
81071748肿瘤干细胞自噬性死亡中趋化因子受体CXCR4调控及干预机制研究国家自然基金委,面上项目2011-01~~2013-1238万元课题负责人
2011CB966200组织干细胞在器官衰老与再生中的作用及调控机制研究973项目重大科学研究计划2011-01~~2015-122500万元课题负责人
09431901000长效重组人胰高血糖素样多肽-1药物的临床前研究上海市科委,重点科技攻关2009-11~~2012-1050万元课题负责人
30873045IDO/TTS平衡格局与肿瘤干细胞免疫逃逸调控机制关系研究国家自然基金委,面上项目2009-01~~2011-1230万元课题负责人
074319102胚胎肝造血干细胞分离纯化新策略和实验性治疗应用的研究上海市科委,重点科技攻关2007-11~~2009-1070万元课题负责人
30670911趋化因子及其受体介导异体效应型记忆CD8+ T细胞致移植物抗宿主病作用及靶向干预研究国家自然基金委,面上项目2007-01~~2009-1227万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Gu Q, Wu Q, Jin M, Xiao Y, Xu J, Mao C, Zhao F, Zhang Y, Zhang Y#. Heme oxygenase-1 alleviates mouse hepatic failure through suppression of adaptive immune responses. J Pharmacol Exp Ther,2012;340(1):2-10
2、Zhao F, Zhang Y, Wang H, Jin M, S, He S, Shi Y, Guo Y, Zhang Y#. Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease. Blood,2011;1179(5):1723-33
3、Mao C , Wang S , Xiao Y , Xu J , Jiang Q , Jin M , Jiang X , Guo H , Ning G , Zhang Y#. Impairment of Regulatory Capacity of CD4+CD25+ Regulatory T Cells Mediated by Dendritic Cell Polarization and Hyperthyroidism in Graves’ Disease. The Journal of Immunology,2011;186(8): 4734-43
4、Xu H, Wu Q, Dang S, Jin M, Xu J, Cheng Y, Pan M, Wu Y, Zhang C, Zhang Y#. Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. PLoS One,2011;6(12):27398-e27399
5、Xiao Y, Xu J, Mao C, Jin M, Wu Q, Zou J, Gu Q, Zhang Y, Zhang Y#. 18β-glycyrrhetinic acid ameliorated Propionibacterium acnes-induced acute liver injury through inhibition of MIP-1α. The Journal of Biological Chemistry,2010;285(2):1128-37
6、Xiao Y, Xu J, Wang S, Mao C, Jin M, Ning G, Xu J, Zhang Y#. Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis. Glia,2010;58(8):932-42
7、Cao Q, Jin Y, Jin M, He S, Gu Q, He S, Qiu Y, Ge H, Yoneyama H, Zhang Y#. Therapeutic effect of MIP-1alpha-recruited dendritic cells on preestablished solid and metastatic tumors. Cancer Letters,2010;295(1):17-26
8、Zhang C, Hao L, Wang L, Xiao Y, Ge H, Zhu Z, Luo Y, Zhang Y, Zhang Y#. Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node etastasis in human colorectal cancer. BMC Cancer,2010;10:184-95
9、Xu J, Zhou T, Zhang Y#. Role of dendritic cells and chemokines in acute graft-versus-host disease. Frontiers in bioscience,2008;13:2065-74
10、He S, Cao Q, Yoneyama H, Ge H, Zhang Y#. MIP-3(alpha) and MIP-1(alpha) rapidly mobilize dendritic cell precursors into the peripheral blood. Journal of Leukocyte Biology,2008;84(6):1549-56
11、Xiao Y, Zhang Y#. Suppressor of cytokine signaling-1, a possible cause for regulatory T cells in hepatitis. Hepatology,2008;48(4):1353-53
12、He S, Cao Q, Qiu Y, Mi J, Zhang J Z, Matsushima K, Jin M, Ge H, Emerson S, Zhang Y, Zhang Y#. A new approach of blocking alloreactive T cell-mediated GVHD by in vivo administration of anti-CXCR3 neutralizing antibody. The Journal of Immunology,2008;181(11):7581-92
13、Hao L, Zhang C, Qiu Y, Wang L, Luo Y, Jin M, Zhang Y, Guo B, Matsushima K, Zhang Y#. Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer. Cancer Letters,2007;253(1):34-42
14、Zhu L, Ji F, Wang Y, Zhang Y, Liu Q, Zhang J Z, Matsushima K, Zhang D, Zhang Y#. Synovial autoreactive T cells in rheumatoid arthritis resist indoleamine IDO-mediated inhibition. The Journal of Immunology,2006;177(11):8226-33
15、Zhang Y, Yoneyama H, Wang Y, Onai N, Ishikawa S. Mobilization of dendritic cell precursors into the circulation by administration of MIP-1alpha in mice. Journal of the National Cancer Institute,2004;96(3):201-9
16、Yoneyama H, Matsuno K, Zhang Y, Nishiwaki T, Kitabatake M. Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules. International Immunology,2004;16(7):915-28
17、Onai N, Kitabatake M, Zhang Y, Kitamura T, Ishikawa H. Pivotal role of CCL25 (TECK)/CCR9 in the formation of gut cryptopatches and consequent appearance of intestinal intraepithelial T lymphocytes. International Immunology,2002;14(7):687-694
18、Yoneyama H, Narumi S, Zhang Y, Murai M, Baggiolini M. Pivotal role of dendritic cell-derived CXCL 10 in the retention of T helper cell 1 lymphocytes in the secondary lymph nodes. Journal of Experimental Medicine,2002;195(10):1257-66
19、Wang Y, Zhang Y, Onai N, Yoneyama H, Hashimoto S. Pivotal role of dendritic cell-derived CXCL 10 in the retention of T helper cell 1 lymphocytes in the secondary lymph nodes. Blood,2002;96(3):201-9
20、Yoneyama H, Matsuno K, Zhang Y, Murai M, Itakura M. Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue in a granulomatous liver disease. Journal of Experimental Medicine,2001;193(1):35-49
21、Onai N, Zhang Y, Yoneyama H, Kitamura T and Matsushima K. Impairment of Lymphopoiesis and myelopoiesis in mice reconstituted with bone marrow-hematopoietic progenitor cells expressing SDF-1-Intrakine. Blood,2000;96(6):2074-80
22、Zhang Y, Wang Y, Ogata M, Hashimoto S. Development of dendritic cells in vitro from murine fetal liver-derived lineage phenotype-negative c-kit+ hematopoietic progenitor cells. Blood,2000;95(1):138-46
23、Ogata M, Zhang Y, Wang Y, Itakura M, Zhang Y. Chemotactic response toward chemokines and its regulation by transforming growth factor-β1 of bone marrow hematopoietic progenitor cell-derived different subset of dendritic cells. Blood,1999;93(10):3225-32
24、Zhang Y, Zhang Y, Ogata M, Chen P, Harada A. Transforming growth factor-polarizes murine hematopoietic progenitor cells to generate Langerhans cell-like dendritic cells through monocyte/macrophage differentiation pathway. Blood,1999;93(4):1208-20
25、Zhang Y, Harada A, Wang J-B, Zhang Y, Hashimoto S. Bifurcated dendritic cell differentiation in vitro from murine lineage phenotype-negative c-kit+ bone marrow hematopoietic progenitor cells. Blood,1998;92(1):118-28


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