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上海交通大学医学院研究生导师简介 陈广洁

上海交通大学 免费考研网/2013-01-09

基本信息
导师姓名: 陈广洁 专业代码: 100102
性别: 专业名称: 免疫学
培养单位: 基础医学院 三级学科/
专业领域:
未设
导师类型: 硕士生导师 专业学位导师:
联系方式: chenguangjie@sjtu.edu.cn 上海交通大学医学院免疫室上海市重庆南路280号5号楼1209室(200025)Email:guangjie_chen@163.com
研究方向 (点击浏览详细信息)
免疫调节与自身免疫病
社会任职
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
2011177β-干扰素对多发性硬化的免疫调节机制研究卫生局科技发展基金2012-01~~2012-123万元课题负责人
11JC1411602IFN-β恢复多发性硬化Treg/Th17平衡作用机制的研究上海市科委基础研究重点项目2012-01~~2014-1215万元子课题负责人
12ZZ103IFN-β恢复多发性硬化IFN-β在实验性自身免疫性脑脊髓炎中的免疫调节机制研究上海市教委科研创新(重点)2012-01~~2014-1216万元课题负责人
C080701免疫活性肽段ergotype在类风湿关节炎中的免疫调节作用研究国家自然基金,面上项目2010-01~~2012-1232万元课题负责人
09YZ104免疫活性肽段ergotope对类风湿关节炎的免疫干预研究上海市教委基金2009-01~~2011-128万元课题负责人
2007126类风湿关节炎中骨桥蛋白调控IL-17表达的机制及发病学意义上海市卫生局,局级课题2008-01~~2010-123万元课题负责人
07ZR14066骨桥蛋白调控IL-17表达在类风湿关节炎中发病机制的研究上海市科委,自然基金2007-11~~2009-1110万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Chen M, Chen G(co-first author)*, Deng S, Liu X, Hutton GJ, Hong J.. IFN-? induces the proliferation of CD4+CD25+Foxp3+ regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis. . J Neuroimmunol.,2012;242:39-46
2、Chang SH, Reynolds JM, Pappu BP, Chen G, Martinez GJ, Dong C. Interleukin-17C Promotes Th17 Cell Responses and Autoimmune Disease via Interleukin-17 Receptor E.. Immunity,2011;35:1–11
3、Niu XY, He DY, Deng SH, Li WY, Xi YB, Xie CY, Jiang T, Zhang J, Dong C, Chen GJ#. Regulatory immune responses induced by IL-1 receptor antagonist inrheumatoid arthritis.. Molecular Immunology,2011;49:290-296
4、Guangjie Chen#. Immunotherapy of Rheumatoid Arthritis:targeting on inflammatory cytokines and autoreactive T cells. . Archivum Immunologiae et Therapiae Experimentalis,2010;58:27-36
5、Xiaoyin Niu, Dongyi He, Xin Zhang, Ningli Li, Jingwu Z Zhang, Chen Dong, Guangjie Chen.#. IL-21 regulates Th17 cells in rheumatoid arthritis.. Human Immunology,2010;71(4):334-341
6、Deng SH, Xi YB, Wang H, Hao J, Niu XY, Li WY, Yue T, Chen GJ#. Regulatory effect of vasoactive intestinal peptide on the balance of Treg and Th17 in collagen-induced arthritis. . Cell Immunol.,2010;265(2):105-10
7、Chen GJ, Zhang X, Li RS, Niu XY, zheng YX, He DY, Xu R, Zhang JW.. Role of Osteopontin in Synovial Th17 Differentiation in Rheumatoid Arthritis. . Arthritis & Rheumatism,2010;62(10):2900–2908
8、Chen MY, Chen GJ(co-first author) *, Nie H, Zhang X, Niu XY, Zang Y, Skinner SM, Zhang JW, Killian JM, Hong J. . Regulatory effect of Interferon-Beta on Production of IL-17 and Osteopontin in CD4+ T Cells in Multiple Sclerosis. . European Journal of Immunology.,2009;39(9):2525-2536
9、Yang H, Qiu LH, Di W, Zhao AM, Chen GJ, Hu K, Lin QD. . Proportional Change of CD4+CD25+ Regulatory T Cells after lymphocyte therapy in Unexplained Recurrent Spontaneous Abortion Patients.. Fertility and Sterility,2009;92(1):301-5
10、Chen GJ, Hao J, Xi YB, Wang W, Wang ZJ, Li NL & Li WY. . The Therapeutic Effect of Vasoactive Intestinal Peptide on Experimental Arthritis is Associated with CD4+CD25+ T Regulatory Cells.. Scandinavian Journal of Immunology.,2008; 68:572–578
11、Yan B, Ye S, Chen GJ, Kuang M, Shen N, Chen SL.. Dysfunctional CD4+CD25+regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-α producing antigen-presenting cells.. Arthritis & Rheumatism,2008;58(3):801-812
12、Yang H, Qiu LH, Chen GJ, Ye Z, Lv CJ, Lin QD.. Proportional Change of CD4+CD25+ Regulatory T Cells in Decidua and Peripheral Blood in Unexplained Recurrent Spontaneous Abortion Patients.. Fertility and Sterility,2008;89(3):656-661
13、Han YP, Chen GJ#. A Method of Analyzing the Structures of Misfolding Proteins like Prion Protein.. Proceeding of 2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE2008),2008;1:253-255
14、Chen GJ, Li NL, Zang YQ, Zhang DQ, He DY, Feng GZ, Ni LQ, Xu R, Wang L, Shen BH, Zhang JW. . Vaccination with selected synovial T cells in Rheumatoid arthritis. . Arthritis & Rheumatism,2007;56(2)453-463


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