上海交通大学医学院研究生导师简介黄莺

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上海交通大学免费考研网/2013-01-09

基本信息

导师姓名:	黄莺	专业代码:	100104
性别:	女	专业名称:	病理学与病理生理学
培养单位:	基础医学院	三级学科/ 专业领域:	未设
导师类型:	硕士生导师	专业学位导师:
联系方式:	huangying@shsmu.edu.cn 上海重庆南路280号，上海交大医学院病理生理学教研室

研究方向 (点击浏览详细信息)

自噬在白血病的发生、发展与治疗中的作用及意义研究

社会任职

科研项目

项目编号	项目名称	课题来源	起止时间	科研经费	承担职责
81270620	早幼粒细胞白血病蛋白与自噬分子LC3 的相互作用及其意义	国家自然基金面上项目	2013-01~~2013-12	16万元	主要责任人
81070431	早幼粒白血病相关融合蛋白 PML-RARa 增强自噬活性及其意义	国家自然基金面上项目	2011-01~~2013-12	34万元	主要责任人
10ZR1417100	二氢叶酸还原酶调控内质网应激性细胞凋亡的分子机制	上海市科委自然基金	2010-04~~2012-03	10万元	主要责任人
07ZR14067	抗白血病蛋白磷脂爬行酶1的信号调控网络的研究	上海市科委,自然基金	2007-11~~2009-11	10万元	课题负责人

学术论文 (#为通讯作者,*为共同第一作者)

1、Ying Huang*, Jia-Kai Hou, Ting-Ting Chen, Xu-Yun Zhao, Zhao-Wen Yan, Jing Zhang, Jie Yang, Scott C. Koganand Guo-Qiang Chen. PML-RARα enhances constitutiveautophagic activity through inhibiting the Akt/mTOR pathway. Autophagy,2011;7(10):1132-44
2、Wu SF, Huang Y*, Hou JK, Yuan TT, Zhou CX, Zhang J, Chen GQ.. The downregulationof onzin expression by PKCepsilon-ERK2 signaling and its potential role in AMLcell differentiation.. Leukemia,2010;24(3):544-551
3、Yuan TT, Huang Y*, Zhou CX, Yu Y, Wang LS, Zhuang HY, Chen GQ.. Nucleartranslocation of dihydrofolate reductase is not a pre-requisite for DNA damageinduced apoptosis.. Apoptosis.,2009;14(5):699-710.
4、Huang Y, Qiu J, Chen GQ, Dong S. . Coiled-coil domain of PML is essential for the aberrant dynamics of PML-RARalpha, resulting in sequestration and decreased mobility of SMRT.. Biochem Biophys Res Commun.,2008;365(2):258-265.
5、Peng ZG, Zhou MY, Huang Y, Qiu JH, Wang LS, Liao SH, Dong S, Chen GQ.. Physical and functional interaction of Runt-related protein 1 with hypoxia-inducible factor-1alpha.. Oncogene.,2008;27(6):839-847
6、Song LP, Zhang J, Wu SF, Huang Y, Zhao Q, Cao JP, Wu YL, Wang LS, Chen GQ.. Hypoxia-inducible factor-1alpha-induced differentiation of myeloid leukemic cells is its transcriptional activity independent.. Oncogene.,2008;27(4):519-527
7、Huang Y, Qiu J, Dong S, Redell MS, Poli V, Mancini MA, Tweardy DJ.. Stat3 Isoforms ? and ?, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3 mapping to its unique C-terminal end.. J Biol Chem.,2007;282(48):34958-34967
8、Qiu J, Huang Y, Chen GQ, Chen Z, Tweardy DJ, Dong S.. Aberrant chromatin remodeling by retinoic acid receptor alpha fusion proteins assessed at the single-cell level.. Mol Biol Cell.,2007;18(10):3941-3951.
9、Han YH, Xia L, Song LP, Zheng Y, Chen WL, Zhang L, Huang Y, Chen GQ, Wang LS.. Comparative proteomic analysis of hypoxia-treated and untreated human leukemicU937 cells.. Proteomics.,2006;6(11):3262-3274.
10、Yan H, Peng ZG, Wu YL, Jiang Y, Yu Y, Huang Y, Zhu YS, Zhao Q, Chen GQ.. Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells.. Haematologica.,2005;90(12):1607-1616.
11、Jiang Y, Xue ZH, Shen WZ, Du KM, Yan H, Yu Y, Peng ZG, Song MG, Tong JH, Chen Z, Huang Y, Lübbert M, Chen GQ.. Desferrioxamine induces leukemic cell differentiation potentially by hypoxia-inducible factor-1 alpha that augments transcriptional activity of CCAAT/enhancer-binding protein-alpha. . Leukemia.,2005;19(7):1239-1247.