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上海交通大学医学院研究生导师简介 陈红专

上海交通大学 免费考研网/2013-01-09

基本信息
导师姓名: 陈红专 专业代码: 100706
性别: 专业名称: 药理学
培养单位: 基础医学院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: yaoli@shsmu.edu.cn 上海市重庆南路280号药理学教研室,200025,63846590*776451
研究方向 (点击浏览详细信息)
药理学和化学生物学研究
社会任职
国家药品审评专家
国家重点新产品审评专家
国家留学基金审评专家
中国药理学会理事
中国高等医学教育理事会理事
教育部药学教学指导委员会成员
上海市药理学会理事长
上海市药学会药理专业委员会主任
《Acta Pharmacol Sin》编委
上海交通大学学报(医学版)执行主编
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
30973509分子伴侣AChE诱导Aβ寡聚体形成的动力学和膜离子通道改变的研究国家自然基金面上项目2010-01~~2012-1232万元课题负责人
2010CB529806重要药用前景动物多肽毒素的临床应用基础研究国家重点基础研究(973计划子项目)2010-01~~2014-12247万元课题负责人
2009ZX09103-077具有多靶点作用抗老年性痴呆候选药物XQ509的研究国家“新药创制”科技重大专项2009-06~~2011-06150万元课题负责人
200802480058具有多靶点作用抗老年性新型美普他酚系列双配基衍生物治疗阿尔茨海默病的化学生物学研究教育部博士点基金2009-01~~2010-128万元课题负责人
30772553新型双配基AChE抑制剂的结构、性质和效应的关系国家自然基金委面上项目2008-01~~2010-1237万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Yu DH, Lu Q, Xie J, Fang C, Chen HZ. #. Peptide-conjugated biodegradable nanoparticles as a carrier to target paclitaxel to tumor neovasculature. Biomaterials,2010;31(8):2278-2292
2、Miezan Ezoulin JM, Shao BY, Xia Z, Xie Q, Li J, Cui YY, Wang H, Dong CZ, Zhao YX, Massicot F, Qiu ZB, Heymans F, Chen HZ#. Novel piperazine derivative PMS1339 exhibits tri-functional properties and cognitive improvement in mice. Int J Neuropsychopharmacol,2009;12(10):1409-1419
3、Liu F, Fang C, Ye X, Lu Q, Yu DH, Zhang WW, Qi H, Xie J, Lieber A, Chen HZ#. Anti-4-1BB scFv immunogene therapy and low dose cyclophosphamide exhibit a synergistic antitumor effect in established murine lung tumors. Cancer Biol Ther,2009;8(8):707-713
4、Lu Q, Yu DH, Fang C, Liu F, Ye X, Zhao Y, Qin J, Guo XK, Liang M, Hu F, Chen HZ#. Influence of E3 region on conditionally replicative adenovirus mediated cytotoxicity in hepatocellular carcinoma cells.. Cancer Biol Ther,2009;8(12):1125-1132
5、Qi H, Ma J, Liu YM, Yang L, Peng L, Wang H, Chen HZ#. Allostatic tumor-burden induces depression-associated changes in hepatoma-bearing mice.. J Neurooncol,2009;94(3):367-372
6、Song MK, Cui YY, Zhang WW, Zhu L, Lu Y, Chen HZ#. The facilitating effect of systemic administration of Kv7/M channel blocker XE991on LTP induction in the hippocampal CA1 area independent of muscarinic activation.. Neurosci Lett,2009;461(1):25-29
7、Zhu X, Zhou W, Cui YY, Zhu L, Li J, Xia Z, Shao B, Wang H, Chen H#. Muscarinic activation attenuates abnormal processing of beta-amyloid precursor protein induced by cobalt chloride-mimetic hypoxia in retinal ganglion cells. Biochem Biophys Res Commun,2009;384(1):110-113
8、Xie Q, Wang H, Xia Z, Lu MY, Zhang WW, Wang XH, Fu Wei, Tang Y, Sheng W, Li W, Zhou W, Zhu X, Qiu ZB, Chen HZ.#. Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on Amyloid-β aggregation.. J Med Chem,2008;51(7):2027-2036
9、Gao X, Wang T, Wu B, Chen J, Chen J, Yue Y, Dai N, Chen H#, Jiang X. Quantum dots for tracking cellular transport of lectin-functionalized nanoparticles.. Biochem Biophys Res Commun,2008;377(1):35-40
10、Gao X, Chen J, Chen J, Wu B, Chen H#, Jiang X.. Quantum dots bearing lectin-functionalized nanoparticles as a platform for in vivo brain imaging. Bioconjug Chem.,2008;19(11):2189-2195
11、Fu J, Feng X, Yuan H, Yan L, Kuang X, Xia Z, Gao X, Yu C, Lu Y, Chen HZ.#. Study of ocular pharmacokinetics of in situ gel system for S(-)-satropane evaluated by microdialysis. J Pharm Biomed Anal,2008;48(3):840-843
12、Liu F, Lu Q, Ye X, Fang C, Zhao Y, Liang M, Hu F, Lieber A, Chen HZ.#. Cancer gene therapy of adenovirus-mediated anti-4-1BB scFv in immunocompetent mice.. Cancer Biol Ther.,2008;7(3):448-453
13、Li J, Shao B, Zhu L, Cui Y, Dong C, Miezan Ezoulin JM, Gao X, Ren Q, Heymans F, Chen HZ. #. PMS777, A Bis-interacting Ligand for PAF Receptor Antagonism and AChE Inhibition, Attenuates PAF-induced Neurocytotoxicity in SH-SY5Y Cells.. Cell Mol Neurobiol,2008;28(1):125-136
14、Ren Z, Ye X, Fang C, Lu Q, Zhao Y, Liu F, Liang M, Hu F, Chen HZ#. Intratumor injection of oncolytic adenovirus expressing HSP70 prolonged survival in melanoma B16 bearing mice by enhanced immune response.immunocompetent mice.. Cancer Biol Ther.,2008;7(2):191-195
15、Song MK, Liu H, Jiang HL, Yue JM, Hu GY, Chen HZ.#. Discovery of talatisamine as a novel specific blocker for the delayed rectifier K(+) channels in rat hippocampal neurons.. Neuroscience.,2008;155(2):469-475
16、Zhang WW, Song MK, Cui YY, Wang H, Zhu L, Niu YY, Yang LM, Lu Y, Chen HZ#. Differential neuropsychopharmacological influences of naturally occurring tropane alkaloids anisodamine versus scopolamine.. Neurosci Lett,2008;443(3):241-245
17、Zhou W, Zhu X, Zhu L, Cui YY, Wang H, Qi H, Ren QS, Chen HZ.#. Neuroprotection of Muscarinic Receptor Agonist Pilocarpine Against Glutamate-induced Apoptosis in Retinal Neurons. Cell Mol Neurobiol,2008;28(2):263-275
18、Fang C, Liu Y, Ye X, Rong ZX, Feng XM, Jiang CB, Chen HZ.#. Synergistically enhanced transdermal permeation and topical analgesia of tetracaine gel containing menthol and ethanol in experimental and clinical studies.. Eur J Pharm Biopharm.,2008;68(3):735-740
19、Li J, Huang H, Miezan Ezoulin JM, Gao XL, Massicot F, Dong CZ, Heymans F, Chen HZ#. Pharmacological profile of PMS777, a new AChE inhibitor with PAF antagonistic activity. . Int J Neuropsychopharmacol,2007;10(1):21-29
20、Wei ZH, He QB, Wang H, Su BH, Chen HZ#. Meta-analysis: the efficacy of nootropic agent Cerebrolysin in the treatment of Alzheimer's disease.. J Neural Transm,2007;114(5):629-634


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