摘要/Abstract

以硒氰酸酯和腙为起始物, 在碱存在条件下实现了一系列硒缩醛类化合物的合成. 本方法对硒氰酸(杂)芳酯以及(杂)芳基、烷基等类型的腙都具有良好的底物适应性和优秀的官能团兼容性, 同时适合克级反应制备, 为硒缩醛类化合物的高效合成提供了一种实用的新策略.
关键词: 硒氰酸酯, 腙, 硒缩醛, 重排
A series of selenoacetals were synthesized from selenocyanates and hydrazones under base condition. (Hetero)aryl selenocyanate and (hetero)aryl, alkyl hydrazones can undergo the process successfully, and shows broad substrate scope and excellent functional group tolerance. This protocol is suitable for gram-scale preparation, providing an efficient and practical synthetic strategy toward selenoacetals.
Key words: selenocyanate, hydrazone, selenoacetal, rearrangement


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