摘要/Abstract

发展了一种对环境友好的乳酸促进的酰胺与胺的氨解的新方法, 该方法能够成功合成一系列芳香、脂肪类酰胺和脲的衍生物. 该方法最显著的特征是催化剂廉价易得、无挥发性溶剂、底物转化率高及产物提纯操作简单.
关键词: 乳酸, 酰胺, 脲, 氨解
An environmentally benign protocol for the transamidation of carboxamides with amines using lactic acid as a green catalyst has been developed. The method has been successfully applied to the synthesis of a wide range of aromatic and aliphatic amides and ureas. The reaction has the advantages of the ready accessibility of the catalyst, solvent-free condition, efficient transformation and green processing.
Key words: lactic acid, carboxamide, urea, transamidation


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