摘要/Abstract

交叉脱氢偶联(CDC)反应是一种直接、有效的形成碳-碳键的方法. 这些反应通常在溶液体系中经外界加热搅拌进行. 随着新型合成方法的发展, 目前实验室中可用于促进CDC反应的替代技术, 如光化学、电化学和机械化学技术迅速兴起, 这些方法作为传统热化学法的完美补充, 为碳-碳键的构建提供了绿色、高效的策略. 对比综述了相同或相似底物参与的两种或两种以上CDC反应激发策略, 希望能够对CDC反应的发展及有机合成新方法的开发提供帮助.
关键词: 交叉脱氢偶联反应, 热化学, 光化学, 电化学, 机械化学
Cross-dehydrogenative coupling (CDC) reactions have been esteemed as one of the straightforward and efficient tool for C—C bond formation. Typically, these reactions are generally realized via solvent-based thermochemistry, using a round bottom flask and a magnetic or mechanical stirrer. With the development of new synthetic strategies, alternative technologies currently available in laboratories that facilitate CDC reactions, such as photochemistry, electrochemistry and mechanochemistry have arisen rapidly, providing green and high efficiency strategies for the construction of C—C bonds which are perfect complement to traditional thermochemistry. In order to compare the advantages of each approaches more clearly, and promote the development of CDC reactions, CDC reactions related to two or more enabling technologies of same or similar substrates are reviewed, hoping to provide help for the development of CDC reaction and the development of new organic synthesis methods.
Key words: cross-dehydrogenative coupling, thermochemistry, photochemistry, electrochemistry, mechanochemistry


PDF全文下载地址:

点我下载PDF