摘要/Abstract

建立了一种能够选择性地发生环丙烷化反应和C—S键断裂反应的催化体系.对于乙烯基苯基硫醚和重氮乙腈（通过原位策略制备）间的反应，在氯化血红素的催化作用下，可得到环丙烷化反应产物；在铁酞菁的催化作用下，则得到C—S键断裂反应产物.该反应体系无需惰性气体保护、无需高温、室温下搅拌1 h即可以中等到优秀的产率获得对应的目标产物.
关键词: 氯化血红素, 重氮化合物, 硫叶立德, 环丙烷化反应, C—S键断裂反应
A catalytic system capable of selectively promoting the cyclopropanation reaction and C—S bond cleavage reaction was established. For the reactions between phenyl vinyl sulfide and diazoacetonitrile (generated by in situ method), the cyclopropanation reaction products were obtained under the catalysis of hemin chloride, and the C—S bond cleavage reaction products were generated in the presence of FePc. All the reations were operated without inert gas protection or high temperature, and the target products were obtained by stirring at room temperature for 1 h in moderate to excellent yields.
Key words: hemin, diazo compound, sulfonium ylide, cyclopropanelation reaction, C-S bond cleavage reaction


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