摘要/Abstract
以磺酰肼和二硫缩烯酮为起始物，在廉价易得的硫酸氢钠作为催化剂条件下，建立了二者之间区域选择性环化合成3-烷硫基取代的吡唑类化合物的方法.在1，4-二氧六环作为介质和80℃加热条件下进行，高效合成了一系列N-磺酰基结构的3-烷硫基吡唑化合物.
关键词: 二硫缩烯酮, 磺酰肼, 环化, 区域选择性, 3-烷硫基吡唑
By using sulfonyl hydrazines and ketene dithioacetals as starting materials, the regioselective annulation providing 3-alkylthiolated pyrazoles has been realized in the low cost and easily available NaHSO4 catalytst. The reactions were realized in 1,4-dioxane medium and 80 ℃ heating, whereby a seris of 3-alkylthiol pyrazoles possessing N-sulfonyl structure have been efficiently synthesized.
Key words: ketene dithioacetal, sulfonyl hydrazine, annulation, regioselectivity, 3-alkylthiopyrazole
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