摘要/Abstract

报道了一种银催化功能化炔烃与有机高价碘（Ⅲ）试剂的立体选择性加成反应.该反应体系底物适用范围广，可以中等到优秀的收率得到烯基酯类化合物.分子内的控制实验证实，有机高价碘试剂分子中的芳基显著促进与其相连的I—O键优先断裂，进而参与后续的立体选择性加成反应.
关键词: 银催化, 炔烃, 高价碘(III)试剂, 立体选择性加成
A silver-catalyzed stereoselective addition reaction of functionalized alkynes with organic hypervalent iodine(Ⅲ) reagents as nucleophiles is reported, providing an approach to vinyl esters in high yields with excellent group tolerance. Intramolecular experiment demonstrates that the presence of aryl group considerably affects the cleavage of I-O bond within hypervalent iodine(Ⅲ) reagents, which is also responsible for the high stereoeselectivity observed in this catalytic system.
Key words: silver catalysis, alkyne, hypervalent(III) iodine reagent, stereoselective addition


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