摘要/Abstract
在氯化胆碱-氯化锌（ChCl/ZnCl2）组成的低共熔溶剂（DES）中，80~90℃条件下，双酮、芳醛与醋酸铵或芳胺反应1~2 h，合成了一系列十氢吖啶1，8-二酮以及N-取代十氢吖啶-1，8-二酮类化合物，产率达75%~92%.该方法反应条件温和、操作简单、反应时间短、产率较高、对环境友好.
关键词: 低共熔溶剂, 十氢吖啶-1,8-二酮, 多组分反应, 绿色化学
In the deep eutectic solvents (DES) consisted of choline chloride/zinc chloride(ChCl/ZnCl2), a series of N-substi-tuted decahydroacridine-1,8-diones and decahydroacridine-1,8-diones were synthesized from diketones, aromatic aldehydes, ammonium acetates or aromatic amines with 75%~92% yields at 80~90 ℃ in 1~2 h. The advantages of the method are wild reaction condition, simple operation, short reaction time, high yield and friendly to environment.
Key words: deep eutectic solvent, decahydroacridine-1,8-diones, multicomponent reaction, green chemistry
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