摘要/Abstract
在温和的反应条件下，较大空间位阻的氨基镁甲基化合物LMgCH3（THF）2[L=N（Ar）（SiMe3），Ar=4，2，6-Me（CHPh2）2C6H2]，可作为高效催化剂前体应用于一系列芳香族和脂肪族羧酸与频哪醇硼烷的脱氧硼氢化反应中.在同样反应条件下观察到羧酸对酯的化学选择性硼氢化.基于密度函数理论（DFT）计算和化学计量反应，提出了两种可能的羧酸硼氢化反应机理.
关键词: 硼氢化, 羧酸, 镁, 主族金属
Sterically bulky amino magnesium methyl complex, LMgCH3(THF)2 (L=NAr(SiMe3), Ar=4,2,6-Me(CHPh2)2-C6H2) has been employed as an efficient precatalyst for the deoxygenate hydroboration of a variety of aromatic and aliphatic acids with pinacolborane (HBpin) under mild reaction condition. Additionally, chemoselective hydroboration of carboxylic acids over esters was also achieved under the standard conditions. Two plausible reaction mechanisms were proposed based on the density functional theory (DFT) calculations and stoichiometric reactions.
Key words: hydroboration, carboxylic acid, magnesium, main group metal
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