摘要/Abstract
探讨了4-十二烷基苯磺酸（DBSA）催化的β-乙硫基-β-吲哚基-α，β-不饱和酮（1）的水相水解反应，实现了3-乙/芳酰乙酰基吲哚（2）的水相合成.研究表明，在回流和10 mol% DBSA存在下，1有效地发生水相水解反应，高产率合成产物2.
关键词: 水相反应, 水解反应, 3-乙酰乙酰基吲哚, β-乙硫基-β-吲哚基-α, β-不饱和酮
4-Dodecylbenzenesulfonic acid (DBSA) catalyzed hydrolysis reaction of β-ethylthio-β-indolyl-α, β-unsaturated ketones (1) in water to yield 3-ethanoyl/aroylacetylindoles (2) was studied. It showed that the hydrolysis of 1 in water smoothly occurred in the presence of 10 mol% DBSA in reflux water, and 2 was obtained in excellent yield.
Key words: aqueous reaction, hydrolysis reaction, 3-acetoacetylindole, β-ethylthio-β-indolyl-α, β-unsaturated ketone
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