摘要/Abstract

报道了一种可见光催化环丙基胺与1，2-二芳基乙二酮衍生物的[3+2]环加成反应，合成了一系列α-氨基呋喃衍生物，该反应条件温和，产率良好，操作简单.这一方法为潜在生物活性分子骨架α-氨基呋喃衍生物的合成提供了一条高效便捷的路径.
关键词: 光氧化还原, 环丙基胺, 1,2-二酮衍生物, [3+2]环加成反应
A visible-light-induced[3+2] annulation of arylcyclopropylamines and 1,2-diarylethanediones was report. A series of α-amino tetrahydrofuran derivatives were synthesized in moderate to good isolated yields under mild reaction conditions. This method would provide an efficient and convenient approach to α-amino tetrahydrofurans which are potentially important buiding blocks in bioactive compounds.
Key words: photoredox, cyclopropylamines, 1,2-diketone derivatives, [3+2] annulation


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