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苯基三氟硼酸钾催化的硅烷还原羰基化合物成醇反应

本站小编 Free考研考试/2022-02-14

摘要/Abstract



研究了以有机硅烷为还原剂选择性还原羰基的反应,在2.5 mol% C6H5BF3K,2.2 epuiv.(EtO)3SiH作用下,甲醇为溶剂,室温下将羰基还原为醇.以中等至较高产率得到目标产物.该方法在羰基还原上表现出良好的选择性,为羰基还原提供了一种新的方法.
关键词: 羰基还原, 有机硅烷, 苯基三氟硼酸钾
The selective reduction of carbonyl group with organosilane as reducing agent was studied with methanol as a solvent under the action of 2.5 mol% C6H5BF3K and 2.2 epuiv. (EtO)3SiH. The target products were obtained in medium to high yield. This method shows good selectivity and provides a new method for carbonyl reduction.
Key words: carbonyl reduction, organosilane, potassium phenyl trifluoroborate


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