摘要/Abstract

报道了一种简单实用的磺酰胺绿色合成方法，以硝基苯和磺酰氯为原料，铁粉为唯一还原剂，纯水作为溶剂.该反应具有反应成本低，溶剂环境友好，反应条件温和，底物适用性广的优点.
关键词: 水, 绿色有机合成, 磺酰胺, 磺酰氯, 铁粉
A simple and practical route for construction of various sulfonamides from nitroarenes and sulfonyl chlorides with iron powder as the sole reductant in water (green solvent) under open-air conditions was developed. The protocol features low-cost, environmentally benign solvent, mild reaction conditions and wide broad substrate scope.
Key words: water, green organic synthesis, sulfonamides, sulfonyl chlorides, iron power


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