摘要/Abstract
报道了一种钯催化、乙酸亚铜盐促进的嘧啶硫醚/喹啉硫醚与炔烃或芳基硼酸的脱硫碳碳偶联反应，合成了一系列2-炔基嘧啶和2-芳基嘧啶/喹啉衍生物，产率良好（64%~87%）.所用的乙酸亚铜盐廉价、稳定，反应产率高，底物适用范围较广.
关键词: 嘧啶硫醚, 嘧啶衍生物, Liebeskind-Srogl反应, 炔烃, 芳基硼酸
An efficient method for carbon-carbon bond formation via desulfurative coupling of pyrimidine thioethers/4-phenylquinoline thioethers with alkynes or arylboronic acids is described. The reaction was promoted by a cheap and stable copper salt[copper(I) acetate] and catalyzed by palladium with good yields and wild substrate scope.
Key words: pyrimidine thioether, pyrimidine derivative, Liebeskind-Srogl reaction, alkyne, arylboronic acid
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