摘要/Abstract

报道了一个在无金属参与的温和条件下，二氯甲烷（DCM）为溶剂，高氯酸三苯基碳正离子（Ph₃CClO₄）介导N-酰基二氢喹啉与类型多样的有机硼试剂的氧化C—H炔基化反应，高效合成了α-炔基取代的1，2-二氢喹啉化合物.此外，相应的C—H烯基化也可兼容，展示出了较好的合成利用价值.
关键词: 二氢喹啉, 碳氢官能化, 炔基化, 碳正离子, 氧化
An efficient synthesis of α-substituted 1, 2-dihydroquinoline compounds through the oxidative C—H functionalization of N-acyl-dihydroquinoline with diverse organoboron reagents mediated by triphenylcarbium perchlorate (Ph₃CClO₄) is reported. The reaction exhibits good functional group tolerance, allowing for C—H alkynylation and alkenylation proceeding smoothly in good yields.
Key words: dihydroquinoline, hydrocarbon functionalization, alkynylation, carbocation, oxidation


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