摘要/Abstract
3-取代咪唑并[1,2-a]吡啶类化合物是一类重要的含氮稠环化合物,在医药、材料等领域具有广泛的应用价值.C-3位C-H官能团化是构建3-取代咪唑并[1,2-a]吡啶类化合物的简单有效方法.按咪唑并[1,2-a]吡啶C-3位的成键类型(C-C、C-S/Se、C-N/P)进行分类,主要介绍了近几年来咪唑并[1,2-a]吡啶等氮杂稠环化合物C-3位C-H官能团化反应进展,并对今后发展作出了展望.
关键词: 3-取代咪唑并[1,2-a]吡啶, C-H官能团化, C-3位
3-Substituted imidazo[1,2-a] pyridines are important N-fused heterocycles with extensive application value in medicine, materials and other fields. C(3)-H bond functionalization strategy was a simple and effective way to build 3-substituted imidazo[1,2-a] pyridines. The recent advances of the access to 3-substituted imidazo[1,2-a] pyridines according to the type of bonding (C-C, C-S/Se, C-N/P) on C-3 position are briefly summarized, and a prospect for the future development is made.
Key words: 3-substituted imidazo[1,2-a] pyridine, C-H bond functionalization, C-3 position
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