xm:王瑜珺
xb:女
zc:研究员
xl:博士
dh:-2323
cz:
dzyj:yjwang@mail.simm.ac.cn
grzy:
zjlb:
zw:
txdz:上海市浦东新区祖冲之路555号2号楼323室
grjj:2004.9-2009.7 沈阳药科大学/中国科学院上海药物研究所联合培养 药理学 博士

1999.9-2003.7 沈阳药科大学 药物制剂 学士

yjfx:1）阿片类物质成瘾机理研究

2）k阿片受体功能研究

3）低成瘾性镇痛药、戒毒药开发

dblz:1. Yu-Chen Lu; Yu-Jun Wang*; Bin Lu; Ming Chen; Ping Zheng; Jing-Gen Liu*; ACC to Dorsal Medial Striatum Inputs Modulate Histaminergic Itch Sensation. ,Journal of Neuroscience, 2018, 38(15): 3823-3839. (期刊论文)

2. Yi-Min Tao#; Chuan Yu#; Wei-Sheng Wang; Yuan-Yuan Hou; Xue-Jun Xu; Zhi-Qiang Chi; Yu-Qiang Ding; Yu-Jun Wang*; Jing-Gen Liu*; Heteromers of mu opioid and dopamine D1 receptors modulate opioid-induced locomotor sensitization in a dopamine-independent manner. , British Journal of Pharmacology, 2017, 174(17): 2842-2861. (期刊论文)

3. Zhong-Guo Chen#; Yu-Jun Wang#; Ruo-Song Chen#; Fan Geng; Chen-Ling Gan; Wei-Sheng Wang; Xing Liu; Hu Zhou; Ling He; Gang Hu*; Jing-Gen Liu*; Ube2b-dependent degradation of DNMT3a relieves a transcriptional brake on opiate-induced synaptic and behavioral plasticity , Molecular Psychiatry, 2019. (期刊论文)

4. Lei Zhang#; Cherkaouia Kibaly#*; Yu-Jun Wang#; Chi Xu; Kyu Young Song; Patrick W McGarrah; Horace H Loh; Jing-Gen Liu*; Ping-Yee Law*; Src-dependent phosphorylation of mu-opioid receptor at Tyr(336) modulates opiate withdrawal., EMBO Molecular Medicine, 2017, 9(11): 1521-1536. (期刊论文)

5. Li Xiao#; Yu-jun Wang#; Mu-mei Zhang#; Wei-wei Wu#; Ling-hui Kong; Yan Ma; Xue-jun Xu; Xiao Liu; Qian He; Yuan-Yuan Qian; Hui-jiao Sun; Hai-hao Wu; Cheng Lin; Huo-ming Huang; Rong-rong Ye; Shuang Jiang; Ru Feng Ye; Congmin Yuan; Sheng-yang Fang; Deng-qi Xue; Xicheng Yang; Hao Chen; Yi-lin Zheng; Lin-qian Yu; Qiong Xie; Lan Zheng; Wei Fu; Wei Li*; Zhuibai Qiu; Jing-gen Liu*; Liming Shao*; Discovery of a highly selective and potent kappa opioid receptor agonist from N-cyclopropylmethyl-7#-phenyl-6,14-endoethanotetrahydro-northebaines with reduced central nervous system, Journal of Medicinal Chemistry, 2019, 62(24): 11054-11070. (期刊论文)

6. Deng, Ying-Zhi; Lu, Yu-Chen; Wu, Wei-Wei; Cheng, Li; Zan, Gui-Ying; Chai, Jing-Rui; Wang, Yu-Jun*; Chen, Zhong; Liu, Jing-Gen; Anteromedial thalamic nucleus to anterior cingulate cortex inputs modulate histaminergic itch sensation. , Neuropharmacology, 2020, 168: 108028. (期刊论文)

7. Yu-Hua Wang; Jing-Rui Chai; Xue-Jun Xu; Ru-Feng Ye; Gui-Ying Zan; George Yun-Kun Liu; Jian-Dong Long; Yan Ma; Xiang Huang; Zhi-Chao Xiao; Hu Dong; Yu-Jun Wang*; Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a kappa Partial Agonist and mu Partial Agonist. , Scientific Reports, 2018, 8(1): 0-14087.

8. Dong-Liang Jiao#; Yan Chen#; Yao Liu; Yun-Yue Ju; Jian-Dong Long; Jiang Du; Chang-Xi Yu*; Yu-Jun Wang*; Min Zhao*; Jing-Gen Liu; SYVN1, an ERAD E3 Ubiquitin Ligase, Is Involved in GABAAalpha1 Degradation Associated with Methamphetamine-Induced Conditioned Place Preference., Frontiers in Molecular Neuroscience, 2017, 10: 0-313. (期刊论文)

9. Qian Wang#; Yu Long#; Ai Hang; Gui-Ying Zan; Xiao-Hong Shu*; Yu-Jun Wang*; Jing-Gen Liu; The anxiolytic- and antidepressant-like effects of ATPM-ET, a novel kappa agonist and mu partial agonist, in mice. , Psychopharmacology (Berl), 2016, 233(12): 2411-2418. (期刊论文)

10. Yu-Jun Wang#; Ai Hang#; Yu-Chen Lu; Yu Long; Gui-Ying Zan; Xue-Ping Li; Qian Wang; Zeng-Xiang Zhao; Ling He; Zhi-Qiang Chi; Jing-Gen Liu*; kappa Opioid receptor activation in different brain regions differentially modulates anxiety-related behaviors in mice , Neuropharmacology, 2016, 110: 92-101.

11. Le-Sha Zhang#; Yu-Jun Wang#; Yun-Yue Ju; Gui-Ying Zan; Chi Xu; Min-Hua Hong; Yu-Hua Wang*; Zhi-Qiang Chi; Jing-Gen Liu*; Role for engagement of beta-arrestin2 by the transactivated EGFR in agonist-specific regulation of delta receptor activation of ERK1/2. , British Journal of Pharmacology, 2015, 172(20): 4847-4863

jyjl:
gzjl:2013.6-至今中国科学院上海药物研究所 助理研究员，副研究员，研究员