中国科学院上海药物研究所导师教师师资介绍简介-于海军

本站小编 Free考研考试/2021-02-10

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yjfx:1. 新型药物递释系统和药用功能辅料开发
2. 智能纳米诊疗系统研究

dblz:代表性论文

1.Bo Hou#, Lei Zhou#, Hui Wang#, Madiha Saeed, Dangge Wang, Zhiai Xu, Yaping Li, Haijun Yu*. Engineering Stimuli-Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy. Adv Mater, 2020. **.

2.Xianli Hu#, Bo Hou#, Zhiai Xu, Madiha Saeed, Zhenmei Gao, Yi Lai, Tong Zhu, Fan Zhang, Wen Zhang, Haijun Yu*. Active Tumor Targeting with Host-Guest Nanoparticles for Combination Immunotherapy of Colorectal Cancer. Adv Sci 2020, **.

3.Ang Gao, Binfan Chen, Jing Gao, Fengqi Zhou, Madiha Saeed, Bo Hou, Yaping Li,* Haijun Yu,* Sheddable Prodrug Vesicles Combating Adaptive Immune Resistance for Improved Photodynamic Immunotherapy of Cancer. Nano Letters. 2020, 20, 353-362.

4.Madiha Saeed, Zhiai Xu, Bruno Geest, Huixiong Xu, Haijun Yu*, Molecular imaging for cancer immunotherapy: Seeing is believing. Bioconjugate Chemistry. 2020, DOI:10.1021/acs.bioconjchem.9b00851.

5.Dangge Wang, Tingting Wang, Haijun Yu,* Bing Feng, Lei Zhou, Fangyuan Zhou, Bo Hou, Hanwu Zhang, Min Luo, Yaping Li*. Engineering nanoparticles to locally activate T cells in the tumor microenvironment. Science Immunology 2019, 4, aau6584.

6.Madiha Saeed, Jing Gao, Yang Shi, Twan Lammers, Haijun Yu*. Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy. Theranostics 2019; 9: 7981-8000.

7.Bing Feng,# Bo Hou,# Zhiai Xu, Madiha Saeed, Haijun Yu,* Yaping Li* Light-Inducible Nanocargos for Self-Amplified Drug Delivery and Combination Chemoimmunotherapy. Adv Mater, 2019, **.

8.Bing Feng,# Zifei Niu,# Bo Hou,# Lei Zhou, Yaping Li,* Haijun Yu*. Enhancing Triple Negative Breast Cancer Immunotherapy by ICG-Templated Self-Assembly of Paclitaxel Nanoparticles. Adv Funct Mater, 2019. **.

9.Tingting Wang#, Dangge Wang#, Haijun Yu*, Bing Feng, Fangyuan Zhou, Lei Zhou, Hanwu Zhang, Shi Jiao, Yaping Li*. A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors. Nat Commun, 2018,9:1532.

10.Fangyuan Zhou,# Bing Feng,# Haijun Yu,* Dangge Wang, Tingting Wang, Yuting Ma, Siling Wang, Yaping Li*, Tumor Microenvironment-Activatable Prodrug Vesicles for Nano-enabled Cancer Immunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade. Adv Mater. 2018, **.

11.Zhihao Zhao#, Weiqi Wang#, Chenxi Li, Yiqiu Zhang, Tianrong Yu, Renfei Wu, Jiayue Zhao, Zhuang Liu, Jian Liu*, Haijun Yu*. Reactive Oxygen Species-Activatable Liposomes (RALP) Regulating Tumor Microenvironment for Photo/Chemo-Dynamic Therapy. Adv Funct Mater, 2019. **.

12.Li Lei, Zhiai Xu*, Xianli Hu, Yi Lai, Jie Xu, Bo Hou, Ya Wang, Haijun Yu*, Yang Tian, Wen Zhang*. Bioinspired Multivalent Peptide Nanotubes for Sialic Acid Targeting and Imaging-Guided Treatment of Metastatic Melanoma. Small. 2019,**.

13.Weiqi Wang, Yilan Jin, Zhiai Xu, Xiao Liu, Sadia Z. Bajwa, Waheed S. Khan, Zhiai Xu, Haijun Yu,* Stimuli-activatable nanomedicine for chemodynamic therapy of cancer. WIREs Nanomedicine & Nanobiotechnology. 2019, DOI: 10.1002/wnan.1614.

14.Qiwen Zhu, Madiha Saeed, Rundi Song, Tao Sun, Chen Jiang, Haijun Yu,* Dynamic covalent chemistry-regulated stimuli-activatable drug delivery systems for improved cancer therapy. Chinese Chemical Letters 2019, DOI:10.1016/j.cclet.2019.12.002.

15.Ang Gao, Xianli Hu, Madiha Saeed, Binfan Chen, Yaping Li, Haijun Yu,* Overview and recent advances in liposomal nanoparticle-based cancer immunotherapy. Acta Pharmacologica Sinica 2019, 40, 1129-1137.

16.Haijun Yu*, Rongqin Huang, Yu Nie, Synthetic nucleic acid nanomedicines: a Chinese perspective (Editorial). The Journal of Gene Medicine. 2019, 21, e3111.

17.Weiqi Wang, Madiha Saeed, Yao Zhou, Lili Yang, Dangge Wang, Haijun Yu*, Non-viral gene delivery for cancer immunotherapy. The Journal of Gene Medicine. 2019, 21, e3092.

18.Jing Gao, Wei-qi Wang, Hai-jun Yu*. Acid-activatable Polymeric Drug Delivery Systems for Cancer Therapy. Acta Polymerica Sinica. 2019, 11, 1156-1166.

19.Fangyuan Zhou#, Bing Feng#, Tingting Wang, Dangge Wang, Zhirui Cui, Siling Wang,* Chunyong Ding, Zhiwen Zhang, Jian Liu, Haijun Yu,* and Yaping Li* Theranostic Prodrug Vesicles for Reactive Oxygen Species-Triggered Ultrafast Drug Release and Local-Regional Therapy of Metastatic Triple-Negative Breast Cancer. Adv. Funct. Mater. 2017, **.

20.Tingting Wang, Dangge Wang, Jianping Liu, Bing Feng, Fangyuan Zhou, Hanwu Zhang, Lei Zhou, Qi Yin, Haijun Yu*, Yaping Li*. Acidity-Triggered Ligand-Presenting Nanoparticles To Overcome Sequential Drug Delivery Barriers to Tumors. Nano Letters. 2017, 17, 5429-5436.

21.Fangyuan Zhou#, Bing Feng#, Tingting Wang, Qingshuo Meng, Dangge Wang, Jianfeng Zeng, Zhiwen Zhang, Siling Wang, Haijun Yu*, Yaping Li*. Programmed Multi-Responsive Vesicles for Enhanced Tumor Penetration and Combination Therapy of Triple-Negative Breast Cancer. Adv. Funct. Mater. 2017, 27, **.

22.Qiang Feng#, Jianping Liu#, Xuanyu Li, Jiashu Sun,* Xinghua Shi, Haijun Yu,* Yaping Li, and Xingyu Jiang* One-Step Microfluidic Synthesis of Nanocomplex with Tunable Rigidity and Acid-Switchable Surface Charge for Overcoming Drug Resistance. Small. 2017, 13:**.

23.Dangge Wang,# Tingting Wang,# Jianping Liu, Haijun Yu,* Shi Jiao, Bing Feng, Fangyuan Zhou, Yuanlei Fu, Qi Yin, Pengcheng Zhang, Zhiwen Zhang, Zhaocai Zhou, Yaping Li,* Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy. Nano Letters, 2016, 16, 5503-5513.

24.Tingting Wang#, Dangge Wang#, Haijun Yu*, Mingwei Wang, Jianping Liu, Bing Feng, Fangyuan Zhou, Qi Yin, Zhiwen Zhang, Yaping Li* Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/ Chemotherapy of the Drug Resistant Tumor. ACS Nano. 2016, 10, 3496-3508.

25.Fangyuan Zhou#, Bing Feng#, Haijun Yu*, Dangge Wang, Tingting Wang, Jianping Liu, Qingshuo Meng, Siling Wang,*, Pengcheng Zhang, Zhiwen Zhang, Yaping Li*, Cisplatin Prodrug-Conjugated Gold Nanocluster: A Theranostic Platform for Treatment of Metastatic Breast Cancer. Theranostics. 2016, 6, 679-687.

26.Dangge Wang#, Tingting Wang#, Zhiai Xu, Haijun Yu*, Bing Feng, Junying Zhang, Chengyue Guo, Qi Yin, Zhiwen Zhang, Yaping Li* Cooperative Treatment of Metastatic Breast Cancer Using Host-Guest Nanoplatform Loading Docetaxel and siRNA. Small. 2016, 12, 488-498.

27.Haijun Yu*,#, Chengyue Guo#, Xianzhi Chen, Bing Feng, Jianping Liu, Tingting Wang, Dangge Wang, Zhirui Cui, Qi Yin, Zhiwen Zhang, Yaping Li* Triple-Layered pH-Responsive Micelleplexes Loaded with siRNA and Cisplatin Prodrug for NF-Kappa B Targeted Treatment of Metastatic Breast Cancer. Theranostic, 2016, 6, 14-27.

28.Haijun Yu*,#, Zhirui Cui#, Pengcheng Yu#, Chengyue Guo, Bing Feng, Tongying Jiang, Siling Wang, Qi Yin, Dafang Zhong, Xiangliang Yang, Zhiwen Zhang, Yaping Li*. pH and near-infrared light-responsive micelles with hyperthermia-triggered tumor penetration and cytoplasm drug release reverse doxorubicin resistance in breast cancer. Adv Funct Mater 2015, 25, 2489-2500. (Front Cover)

29.Chongsheng Guo#, Haijun Yu#,*, Bing Feng, Weidong Gao, Mei Yan, Zhiwen Zhang, Yaping Li*, Shaoqing Liu*. Highly efficient ablation of metastatic breast cancer using ammonium-tungsten-bronze nanocube as a novel 1064 nm-laser-driven photothermal agent. Biomaterials 2015, 52, 407-416.

30.Dangge Wang, Zhiai Xu, Haijun Yu*, Xianzhi Chen, Bing Feng, Zhirui Cui, Bin Lin，Qi Yin, Zhiwen Zhang, Chunying Chen, Jun Wang, Wen Zhang, Yaping Li*. Treatment of metastatic breast cancer by combination of chemotherapy and photothermal ablation using doxorubicin-loaded DNA wrapped gold nanorods. Biomaterials. 2014, 35, 8374–8384.

jyjl:2001.09-2006.12中国科学院长春应用化学研究所，生物医用高分子，博士