研究队伍
姓名:
　徐明华性别:
　男
职称:
　研究员学历:
　博士
电话:
　021-50807388传真:
　
电子邮件:
　xumh@mail.shcnc.ac.cn个人主页:
　
通讯地址:
　上海市祖冲之路555号　201203

简历：
1999年7月毕业于中国科学院上海有机化学研究所，获得理学博士学位；同年8月赴美国，先后在美国弗吉尼亚大学(UniversityofVirginia)化学系和乔治城大学医学研究中心(GeorgetownUniversityMedicalCenter)从事博士后工作研究。2003年7月底回国，先期受聘于中国科学院上海有机化学研究所，后入选中国科学院“百人计划”。2005年7月起任中国科学院上海药物研究所研究员、课题组长。

研究方向：
主要从事有机不对称合成及有重要生理活性化合物的合成研究。

专家类别：
研究员；百人计划

职务：
中科院上海药物所研究员、博士生导师、研究组长

科研成果：


承担科研项目情况：

1. 国家自然科学基金面上项目2010-2012(20972172，主持)
2. 上海市科技启明星跟踪2008-2010(08QH14027，主持)
3. 国家自然科学基金创新群体项目2008-2010(20721003，子课题负责)
4. 国家自然科学基金重点项目2007-2010(20632060，子课题负责)
5. 国家自然科学基金面上项目2007-2009(20672123，主持)
6. 中国科学院百人计划项目2005-2009(主持)

社会任职：


获奖及荣誉：

1. 2005中国化学会青年化学奖
2. 2005中国科学院“百人计划”
3. 2005上海市青年科技启明星
4. 2006JAPSAsianCoreProgramLectureshipAward(2007,Japan)
5. 2007药明康德生命化学研究奖（三等奖）
6. 2007JSPSAsianCoreProgramLectureshipAward(2008,Japan)
7. 2008中科院上海分院杰出青年科技创新人才提名奖
8. 2008上海市青年科技启明星后
9. 2008AsianCoreProgramLectureshipAward(2009,Singapore)

应邀担任国际知名学术期刊J.Am.Chem.Soc.,Org.Lett.,J.Org.Chem.,Chem.Commun.,Tetrahedron,TetrahedronLett.等的审稿人。

代表论著：
近期发表论文选录

1. BoZhang,Ming-HuaXu*,andGuo-QiangLin*,“CatalyticEnantioselectiveSynthesisofChiralPhthalidesbyEfficientReductiveCyclizationof2-AcylarylcarboxylatesunderAqueousTransferHydrogenationConditions”,OrganicLetters2009,11,4712-4715.
2. LeiChen,andMing-HuaXu*,“ANewApproachtoPyrrolocoumarinDerivativesbyPd-CatalyzedReactions:ExpedientConstructionofPolycyclicLamellarinScaffold”,Adv.Synth.Catal.2009,351,2005-2012.
3. MinLiu,Xing-WenSun,Ming-HuaXu*,andGuo-QiangLin*,“HighlyEfficientAsymmetricSynthesisofVinylicAminoAlcoholsbyZn-PromotedBenzoyloxyallylationofChiralN-tert-ButanesulfinylImines:FacileandRapidAccessto(-)-Cytoxazone”,Chem.Eur.J.2009,15,10217-10224.
4. Du-MingJi,andMing-HuaXu*,“InBr3-CatalyzedDirectAlkynylationofNitroneswithTerminalAlkynes:anEfficientSynthesisofN-Hydroxy-propargylAmines”,TetrahedronLett.2009,50,2952-2955.(HighlightedbySYNFACTS,2009,7,0775)
5. Xing-WenSun,Ming-HuaXu*andGuo-QiangLin*,“RapidAssemblyofanti-1,3-DiolUnitswith2-QuaternaryCarbonStereocenterviaSamariumDiiodide-PromotedTandemAldol/Evans-TishchenkoReaction”,TetrahedronLett.2009,50,3381-3384(50thAnniversarySpecialIssue).
6. Chen-GuoFeng,Zhi-QianWang,ChengShao,Ming-HuaXu*,andGuo-QiangLin*,“HighlyPracticalCatalyticAsymmetric1,4-AdditionofArylboronicAcidsinWaterUsingNewHydrophilicChiralBicyclo[3.3.0]DieneLigands”,OrganicLetters2008,10,4101-4104.(HighlightedbySYNFACTS,2008,11,1181)
7. Guo-QiangLin,Ming-HuaXu,Yu-WuZhongandXing-WenSun,“AnAdvanceonExploringN-tert-Butanesulfinyl-iminesinAsymmetricSynthesisofChiralAmines”,Acc.Chem.Res.2008,41,831-840.
8. Chen-GuoFeng,Zhi-QianWang,PingTian,Ming-HuaXu*,andGuo-QiangLin*,“EasilyAccessibleC2-SymmetricChiralBicyclo[3.3.0]DienesasLigandsforRhodium-CatalyzedAsymmetric1,4-Addition”,Chem.Asia.J.2008,3,1511-1516.(SpecialIssue:InHonorofProfessorRyojiNoyoriforHis70thBirthday)
9. Xing-WenSun,MinLiu,Ming-HuaXu*,andGuo-QiangLin*,“RemarkableSaltEffectonIn-MediatedAllylationofN-tert-ButanesulfinylIminesinAqueousMedia:HighlyPracticalAsymmetricSynthesisofChiralHomoallylicAminesandIsoindolinones”,OrganicLetters2008,10,1259-1262.(HighlightedbySYNFACTS,2008,06,0597;AbstractedbyChemInform,2008,39,35-056)
10. Zhi-QianWang,Chen-GuoFeng,Ming-HuaXu*,andGuo-QiangLin*,“DesignofC2-SymmetricTetrahydropentalenesasNewChiralDieneLigandsforHighlyEnantioselectiveRh-CatalyzedArylationofN-TosylarylimineswithArylboronicAcids”,J.Am.Chem.Soc.2007,129,5336-5337.(HighlightedbySYNFACTS,2007,08,0847andOrganicChemistryPortal;AbstractedbyChemInform,2007,38,37-073).
11. Xing-WenSun,Ming-HuaXu*andGuo-QiangLin*,“Room-TemperatureHighlyDiastereoselectiveZn-MediatedAllylationofChiralN-tert-ButanesulfinylImines:RemarkableReactionConditionControlledStereoselectivityReversal”,OrganicLetters2006,8,4979-4982.(HighlightedbyChemistry.OrgoftheAmericanChemicalSocietyasa“HeartCut”(Dec4,2006);alsohighlightedbySYNFACTS,2006,12,1266).
12. Yu-WuZhong,Yi-ZhouDong,KaiFang,KenjiIzumi,Ming-HuaXu*andGuo-QiangLin*,“AHighlyEfficientandDirectApproachforSynthesisofEnantiopureα-AminoAlcoholsbyReductiveCross-CouplingofChiralN-tert-ButanesulfinylImineswithAldehydes”,J.Am.Chem.Soc.2005,127,11956-11957.(HighlightedbySYNFACTS,2005,3,0331;AbstractedbyChemInform,2005,37,01-088).
13. Ling-LinHuang,Ming-HuaXu*andGuo-QiangLin,“ANewEntrytoEfficientAsymmetricSynthesisofOpticallyActive?,?-Substituted?-ButyrolactonesUsingCarbohydrateDerivedAmideasbothaChiralAuxiliaryandaProtonSource”,J.Org.Chem.2005,70,529-532.
14. Yu-WuZhong,KenjiIzumi,Ming-HuaXu*andGuo-QiangLin,“HighlyDiastereoselectiveandEnantioselectiveSynthesisofEnantiopureC2-SymmetricalVicinalDiaminesbyReductiveHomocouplingofChiralAromaticN-tert-ButanesulfinylImines”,OrganicLetters2004,6,4747-4750.
15. Yu-WuZhong,Ming-HuaXu*andGuo-QiangLin,“SamariumDiiodide-InducedAsymmetricSynthesisofOpticallyPureUnsymmetricalVicinalDiaminesbyReductiveCross-CouplingofNitroneswithN-tert-ButanesulfinylImines”,OrganicLetters2004,6,3953-3956.(HighlightedbyChemistry.OrgoftheAmericanChemicalSocietyasa“HeartCut”(Nov15,2004);alsohighlightedbyAngew.Chem.Int.Ed.2005,44,7833.).