姓名:
宣利江性别:
男
职称:
研究员学历:
博士
电话:
86-21-20231968传真:
86-21-20231968
电子邮件:
ljxuan@mail.shcnc.ac.cn个人主页:
通讯地址:
上海市浦东新区海科路501号 201203
简历:
1990年毕业于上海医科大学;1995年于中国科学院上海药物研究所获博士学位,留所任助理研究员;1996年赴日本九州大学药学部生药学教室进行博士后工作,1998年回所工作,期间曾赴美国加州大学圣地亚哥分校Scripps海洋学研究所访问研究。
研究方向:
以产业化为目标,以天然药用资源的水溶性成分研究为基础,探索中药的作用机理和物质基础,寻找和发现结构新颖的天然活性化合物及先导化合物,并在此基础上开展新药创制和中药现代化的研究。
专家类别:
研究员
职务:
中科院上海药物所研究员、博士生导师、研究组长
科研成果:
承担科研项目情况:
承担“重大新药创制”国家科技重大专项,上海市重大产业科技攻关项目等多个课题。
社会任职:
获奖及荣誉:
- 2011年获国家技术发明二等奖
- 2011年获中国药学发展奖杰出青年学者奖
- 2007年获上海市技术发明一等奖
- 2006年获中国国际工业博览会创新奖
- 2006年获上海市科教党委系统青年科技创新人才奖
- 2005年获中国科学院先进集体2004年获上海药学会药学科技奖
- 2003年上海化学化工学会吴蕴初专项奖提名奖
代表论著:
- Xiao-PingHu,Shu-WeiZhang,Shan-ShanLiu,andLi-JiangXuan.NewAnthraquinoneandIridoidGlycosidesfromtheStemsofHedyotishedyotidea.HelveticaChimicaActa,2011,94:675-685.
- ZhouTong;ZhangXiao-Hui;ZhangShu-Wei;LiuShan-Shan;XuanLi-Jiang.NewPhenylpropanoidsandInVitroα-GlucosidaseInhibitorsfromBalanophorajaponica.Plantamedica,2011,77(5),477-81.
- Zhou,Tong;Zhang,Shu-wei;Liu,Shan-shan;Cong,Hai-jian;Xuan,Li-jiang.DaphnodorindimersfromEdgeworthiachrysanthawithα-glucosidaseinhibitoryactivity.PhytochemistryLetters,2010,3(4),242-247.
- Chen,Li;Xuan,Li-Jiang;Wang,Yi-Ping.EffectsofmagnesiumlithospermateBanditsanaloguesonCa2+homeostasisinculturedratthoracicaortavascularsmoothmusclecells.PlantaMedica,2009,75(15),1573-1579.
- Yu,Juan;Zhang,Hao-Hao;Yu,Qiang;Xuan,Li-Jiang.PrenylatedPhenolsfromSabiajaponica.HelveticaChimicaActa,2009,92(9),1880-1888.
- Liu,Shan-Shan;Zhou,Tong;Zhang,Shu-Wei;Xuan,Li-Jiang.ChemicalConstituentsfromClerodendrumbungeiandTheirCytotoxicActivities.HelveticaChimicaActa,2009,92(6),1070-1079.
- Zhang,Xiao-Hui;Liu,Shan-Shan;Xuan,Li-Jiang.CyclopentenylglycinesandotherconstituentsfromAlangiumchinense.BiochemicalSystematicsandEcology(2009),37(3),214-217.
- Wu,Jun;Zhou,Tong;Zhang,Shu-wei;Zhang,Xiao-hui;Xuan,Li-jiang.CytotoxicterpenoidsfromthefruitsofVitextrifoliaL.PlantaMedica,2009,75(4),367-370.
- XiaoKai,ZhangHongjun,XuanLijiang,ZhangJuan,XuYaming,BaiDonglu.Stilbenoids:chemistryandbioactivities.Studiesinnaturalchemistry,200834,453-646.
- XiaohuiZhang,ShuweiZhang,LijiangXuan.ThreenewfurannosesquiterpenoidsfromBombaxmalabaricumandrevisedNMRassignmentofHibisconeC.Heterocycles,2008,75,661-668.
- ShanshanLiu,HuilinZhu,ShuweiZhang,XiaohuiZhang,QiangYu,andLijiangXuan.AbietanediterpenoidsfromClerodendrumbungei.J.Nat.Prod.2008,71,755–759.
- JunWu,XiaohuiZhang,ShuweiZhang,LijiangXuan.ThreenovelcompoundsfromtheflowersofBombaxmalabaricum.HelverticaChimicaActa,2008,91,136-143.
- Wang,Li;Zhang,Qiang;Li,Xiaochuan;Lu,Youli;Xue,Zhimou;Xuan,Lijiang;Wang,Yiping.PharmacokineticsandmetabolismoflithospermicacidbyLC/MS/MSinrats.InternationalJournalofPharmaceutics2008,350(1-2),240-246.
- ShuweiZhang,LijiangXuan.CyclopentenoneandfuranderivativefrommyceliaofCordycepscicadae.TheJournalofAntibiotics,2008,61,43-45.
- Zhang,Xiao-Hui;Zhu,Hui-Lin;Yu,Qiang;Xuan,Li-Jiang.CytotoxiccardenolidesfromStreptocaulongriffithii.Chemistry&Biodiversity,2007,4(5),998-1002.
- Zhang,Shu-Wei;Xuan,Li-Jiang.Fivearomaticsbearinga4-O-methylglucoseunitfromCordycepscicadae.HelveticaChimicaActa,2007,90(2),404-410.
- Jiang,Lili;Zhang,Shuwei;Xuan,Lijiang.OxanthroneC-glycosidesandepoxynaphthoquinolfromtherootsofRumexjaponicus.Phytochemistry,2007,68(19),2444-2449.
- Zhang,Xiaohui;Zhu,Huilin;Zhang,Shuwei;Yu,Qiang;Xuan,Lijiang.SesquiterpenoidsfromBombaxmalabaricum.JournalofNaturalProducts,2007,70(9),1526-1528.
- Li,Xiaochuan;Yu,Chen;Wang,Li;Lu,Youli;Wang,Wenyi;Xuan,Lijiang;Wang,Yiping.SimultaneousdeterminationoflithospermicacidBanditsthreemetabolitesbyliquidchromatography/tandemmassspectrometry.JournalofPharmaceuticalandBiomedicalAnalysis,2007,43(5),1864-1868.
- Li,Xiaochuan;Yu,Chen;Lu,Youli;Gu,Yunlong;Lu,Jie;Xu,Wei;Xuan,Lijiang;Wang,Yiping.Pharmacokinetics,tissuedistribution,metabolism,andexcretionofdepsidesaltsfromSalviamiltiorrhizainrats.DrugMetabolismandDisposition,2007,35(2),234-239.