姓名:
黄成钢性别:
男
职称:
研究员学历:
博士
电话:
传真:
电子邮件:
cghuang@mail.shcnc.ac.cn
通讯地址:
上海市祖冲之路555号 201203
简历：
1981年毕业于桂林医学院药学系，1989年硕士毕业于黑龙江中医药大学中药系，1998年博士毕业于浙江大学化学系，2000年中国科学院上海药物研究所博士后出站留所工作。
研究方向：
中药复方药效物质基础及作用机理研究，现代中药研究开发
专家类别：
研究员
职务：
中科院上海药物所研究员、博士生导师、研究组长、中药现代研究中心副主任
科研成果：
承担科研项目情况：
多年从事中药及复方的基础研究和新药开发。采用体内多成分分析等先进方法研究中药及复方药效物质基础，特别是口服后吸收进入体内的小分子有效成分群，寻找体内直接作用的药效物质。在此基础上研发单味中药或复方的现代组分中药。主持完成了包括国家基金委重大研究计划项目，国家863项目，国家新药创制重大专项项目，中科院知识创新重要方向项目，上海市科技发展基金项目等多项国家和省部级科研项目。
社会任职：
获奖及荣誉：
代表论著：
- ChunhuiMa,ZhixiongLi,ChenggangHuang*etal,IdentificationofmajoralkaloidsinraturinebyHPLC-DAD-ESI-MS/MSmethodfollowingoraladministrationofCortexPhellodendridecoction,HelveticaChimicaActa，2009，92：379-398
- HaiyanZhu,YuanyuanZhang,ChenggangHuang*etal,InVivoandinVitroAntiviralActivitiesofCalycosin-7-O-β-D-glucopyranosideagainstCoxsackieVirusB3,Biological&PharmaceuticalBulletin,2009,32(1):68-73
- ChunhuiMa,YihongTang,ChenggangHuang*etal,IdentificationofmajoralkaloidsandsteroidalsaponinsinratserumbyHPLC-DAD-MS/MSmethodfollowingoraladministrationofHuangbai-Zhimuherb-pairExtract,BiomedicalChromatography,2008，22（8）：835-850
- ChunhuiMa,LongxingWang,ChenggangHuang*etal,Identificationofmajorxanthonesandsteroidalsaponinsinraturinebyliquidchromatography-atmosphericpressurechemicalionizationmassspectrometrytechnologyfollowingoraladministrationofRhizomaAnemarrhenaedecoction,BiomedicalChromatography,2008,22(10):1066-1083
- Chun-huiMa,Ming-songFan,Cheng-gangHuang*etal,CytotoxictriterpenoidSaponinsfromVaccariasegetalis,JournalofAsianNaturalProductsResearch,2008,10(2):177-184
- GuanYe,RongrongMa,ChenggangHuang*etal,Determinationofcalycosin7-O-β-D-glucosideinratplasmaandurinebyHPLC,BiomedicalChromatography,2007,21:762-767
- HuiWang,Chun-huiMa,ChenggangHuang*etal,Identificationanddeterminationoffourmetabolitesofmangiferininraturine,JournalofPharmaceuticalandBiomedicalAnalysis,2007,45:793-798
- YihongTang,YuanyuanZhang,ChenggangHuang*etal,Ahigh-performanceliquidchromatographicmethodforsaikosaponinaquantificationinratplasma,BiomedicalChromatography,2007,21(5):458-62
- GuanYe,JingjingFang,ChenggangHuang*etal,StructureelucidationandcompleteNMRspectralassignmentsofanovelsesquiterpeneglycosidefromIxerissonchifoli.,MagneticResonanceinChemistry,2007,45(4):362-363
- Kai-chengZhu,Chun-huiMa,Cheng-gangHuang*etal,TwonewsecoiridoidGlycosidesfromTripterospermumChinense(Migo),HelveticaChimicaActa,2007,90(2):291-296
- GuanYe,HuaPeng,ChenggangHuang*etal,AnewhopanetriterpenefromDipentodonsinicus(Celastraceae),BiochemicalSystematicsandEcology,2007,35:905-908
- YuanyuanZhang,HaiyanZhu,C.G.Huang*etal,AntiviraleffectsofsophoridineagainstcoxsackievirusB3anditspharmacokineticsinrats,LifeSciences,2006,78:1998-2005
- GuanYe,HaiyanZhu,ChenggangHuang*etal,DeterminationofgeniposideinraturineafteroraladministrationoftraditionalChinesemedicinalpreparationYin-Zhi-Kudecoctionbyhigh-performanceliquidchromatography,Journalofchromatographicscience,2006,44(4):227-300
- YuanyuanZhang,HaiyanZhu,ChenggangHuang*etal,AstragalosideIVexertsantiviraleffectsagainstcoxsackievirusB3byupregulatinginterferon-γ,JournalofCardiovascularPharmacology,2006,47(2):190-195.
- YHTang,HYZhu,CGHuang*etal,Determinationofhumanplasmaproteinbindingofbaicalinbyulterfiltrationandhighperformanceliquidchromatography,BiomedicalChromatography，2006,20:1116-1119
- GuanYe,HaiyanZhu,ChenggangHuang*etal,SPE-HPLCmethodforthedeterminationandpharmacokineticstudiesongeniposideinratserumafteroraladministrationoftraditionalChinesemedicinalpreparationYin-Zhi-Kudecoction,BiomedicalChromatography,2006,20:743-747
- C.H.Ma,W.Ke,C.G.Huang*etal,Large-scaleisolationandpurificationofscoparonefromHerbaartemisiaescopariaebyhigh-speedcounter-currentchromatography,Chromatographia,2006,64:83-87
- HuiWang,Yi-HongTang,Cheng-GangHuang*etal,High-performanceliquidchromatographicmethodforthedeterminationofmangiferininratplasmaandurine.BiomedicalChromatography，2006,20:1304-1308
- ChenggangHuang*，ChunhuiMa,YihongTangetal,ClinicalChemistryResearch，Chapter4：IdentificationandAnalysisofEffectiveComponentsinAnimalBiofluidsfollowingAdministrationofNaturalMedicines，NovaSciencePublishersInc.NY,March,2009
