卢燕

天然药物学, 副教授, 博士生导师



姓名
 卢燕
性别
 女

职称
 副教授
学历
 博士

电话
 
传真


电子邮件
 luyan@fudan.edu.cn
个人主页


通讯地址
上海市张衡路826号化学实验北楼309室





教育经历
1996.09 – 2003.07山东中医药大学中药学院
2003.09 – 2006.07复旦大学药学院

工作经历
2006.07 – 2011.10复旦大学药学院，讲师
2011.11 – 2012.12美国北卡莱罗那大学教堂山分校(UNC),访问****
2011.11. – 目前复旦大学药学院，副教授

承担科研项目情况



1.国家重点研发计划，中药的分子标识研究以及“中药智慧云”信息平台建设（2019YFC**）分任务
2. 西藏自治区重大科技专项，藏药“五味甘露浴”药效物质基础研究与数据库建设（XZ201801-GH-13）子课题
3.西藏自治区中央引导地方项目，藏药清热类药物活性物质与靶标分子的研究（XZ202001YD0003C）子课题
4. 国家自然科学基金面上项目，多基源藏药圆柏的清热药效物质基础与品质评价（**）
5. 科技部十二五“重大新药创制”重大科技专项，多糖类药物制备及质量控制关键技术研究（2012ZX**-003）子课题
6. 科技部十一五“重大新药创制”重大科技专项， 与药效相关的中药质量评价关键技术研究（2009ZX09502-021）子课题
7. 国家自然科学基金青年科学基金项目，鱼腥草的抗补体活性成分与清热解毒药效物质基础研究（**）
8. 2010、2015版《中国药典》一部标准研究，滇鸡血藤、复方鸡血藤膏、南五味子、通关藤、虎杖、狼毒、京大戟等

研究方向


1. 中草药的活性成分与质量评价
2. 中药提取物及其制剂的质量标准与产品开发

代表性成果




1. Yan Lu#, Ya-Si Huang#, Chin-Ho Chen, Toshiyuki Akiyama, Susan L. Morris-Natschke, Yung-Yi Cheng, Ih-Sheng Chen, Sheng-Zehn Yang, Dao-Feng Chen*, Kuo-Hsiung Lee*. Anti-HIV tigliane diterpenoids from Reutealis trisperma. Phytochemistry, 2020, 174: 112360
2.Yiting Yang#, Deji, Zelong Fu, Xieli Wang, Daofeng Chen, Hui Xie*, Yan Lu*. Molecular Identification Based on Chloroplast Sequences and Anti-complementary Activity Comparison of Juniperus Samples fromthe Qinghai-Tibet Plateau. Planta Medica, 2020, DOI 10.1055/a-1194-0471
3. Long Xia, Deji, Mengxia Zhu, Daofeng Chen^*, Yan Lu^*. Juniperus pingii var. wilsoniiacidic polysaccharide: extraction, characterization and anticomplement activity. Carbohydrate Polymers, 2020, 231:115728.
4. Jiangyan Huo, Yan Lu^*, Long Xia, Daofeng Chen^*. Structural characterization and anticomplement activities of three acidic homogeneous polysaccharides from Artemisia annua. Journal of Ethnopharmacology, 2020, 247: 112281.
5. Haijuan Zhi, Xin Jin, Haiyan Zhu, Hong Li, Yunyi Zhang, Yan Lu^*, Daofeng Chen^*. Exploring the effective materials of flavonoids-enriched extract from Scutellaria baicalensis roots based on the metabolic activation in influenza A virus induced acute lung injury. Journal of Pharmaceutical and Biomedical Analysis, 2020, 177: 112876.
6. Yan Lu^#, Juanjuan Zhang^#, Jiangyan Huo, Daofeng Chen^*. Structural characterization and anti-complementary activities of two polysaccharides from Houttuynia cordata. Planta Medica, 2019, 85: 1098-1106.
7. Beibei Li, Mengxue Dong, Ji De, Li Ye, Daofeng Chen, Yan Lu^*. Structural characterization and anti-proliferation activities against tumor cells of an arabinogalactan from Juniperus convallium. Molecules, 2019, 24: 1850.
8. Qianbo Song, Xiao Xia, Chongmin Ji, Daofeng Chen, Yan Lu^*. Optimized flash extraction and UPLC-MS analysis on antioxidant compositions of Nitraria sibiricafruit. Journal of Pharmaceutical and Biomedical Analysis, 2019, 172: 379-387.
9. Zelong Fu^#, Long Xia^#, Ji De, Mengxia Zhu, Yan Lu^*, Daofeng Chen^*. Beneficial effects on H1N1-induced acute lung injury and structure characterization of anti-complementary acidic polysaccharides from Juniperus pingiivar. wilsonii. International Journal of Biological Macromolecules, 2019, 129: 246-253.
10. Yan Lu^#, Yun Jiang^#, Lijun Ling, Yunyi Zhang, Hong Li, Daofeng Chen^*. Beneficial effects of Houttuynia cordatapolysaccharides on ‘two-hit’ acute lung injury and endotoxic fever in rats are associated with anti-complementary activities.Acta Pharmaceutica Sinica B, 2018, 8(2): 218-227.
11. Ji De, Y Lu^*, Lijun Ling, Nan Peng, Yang Zhong^*. Essential oil composition and bioactivities of Waldheimia glabra(Asteraceae) from Qinghai-Tibet plateau. Molecules, 2017, 22(3): 460.
12. Yun Jiang, Yan Lu^*, Yunyi Zhang, Daofeng Chen^*. Anti-complementary constituents of Houttuynia cordata and their targets in complement activation cascade. Natural Product Research, 2014, 28(6): 407-410.