赵伟利

药物化学, 研究员, 博士生导师


姓名
 赵伟利
性别
 男

职称
 研究员
学历
 博士

电话
 
传真
 

电子邮件
 zhaoweili@fudan.edu.cn
个人主页


通讯地址
 张衡路826号实验南楼421


教育经历 1998.10-2002.10瑞士联邦苏黎世理工学院，博士后
1998.07-1998.10美国加州理工学院，博士后
1997.07-1998.07美国加州大学尔湾分校，访问****
1994.07-1997.07中国科学院感光化学研究所，博士
1987.07-1990-07中国科学院感光化学研究所，硕士
1983.07-1987.07武汉大学化学系，学士
工作经历 2009.04- 复旦大学药学院， 研究员、博导
2005.11－2009.03罗氏研发（中国）有限公司，药物研发副主任、主任
2002.10-2005.11瑞士联邦苏黎世理工学院“Wissenschaftlicher Mitarbeiter”
1990.07-1994.07河南大学物理系，助教，讲师

研究方向
1.抗肿瘤小分子靶向药物研究
2.有机合成方法
3.荧光探针及传感器

代表性论著
1. Response to Comment on “Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability Superoxide Detection in Live Cells and in Zebrafish Embryos”. Xiuhong Lu, Guangyu Lin, Xiaochun Dong*, Weili Zhao*, Zhongjian Chen*, ACS Sens., 2019, 4, 3084-3087.
2. Pyridinium substituted BODIPY as NIR fluorescent probe for simultaneous sensing of hydrogen sulphide/glutathione and cysteine/homocysteine. Jian Zhang, Xin Ji, Junliang Zhou, Zhongjian Chen*, Xiaochun Dong*, Weili Zhao*, Sens. Actuators B, 2018, 257, 1076–1082.
3. Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos. Xiuhong Lu, Zhongjian Chen*, Xiaochun Dong*, Weili Zhao*, ACS Sens., 2018, 3, 59?64.
4. Overcoming the resistance mechanisms of Smoothened inhibitors. Xiaochun Dong, Chenglin Wang, Zhongjian Chen*, Weili Zhao*, Drug Discov. Today, 2018, 23, 704–710.
5. A mitochondria-targeted turn-on ?uorescent probe for the detection of glutathione in living cells. Jian Zhang, Xiaolong Bao, Junliang Zhou, Fangfang Peng, Hang Ren, Xiaochun Dong*, Weili Zhao*, Biosens. Bioelectron., 2016, 85, 164–170.
6. A multi-functional probe to discriminate Lys, Arg, His, Cys, Hcy and GSH from common amino acids.Xiuhong Lu, Wen Wang, Qian Dong, Xiaolong Bao, Xianfeng Lin, Weixing Zhang, Xiaochun Dong*, Weili Zhao*, Chem. Commun. 2015, 51, 1498-1501.
7. A Facile Copper-Catalyzed One-Pot Domino Synthesis of 5,12-Dihydroindolo[2,1-b]quinazolines
Min Jiang, Xiaochun Dong, Weili Zhao*, Org. Lett. 2012, 14, 1420-1423.
8. Microwave-Assisted Solventless Reaction of Iridium-Catalyzed Alkylation of Amines with Alcohols in the Absence of Base.Weixing Zhang, Xiaochun Dong*, Weili Zhao*, Org. Lett. 2011, 13 (19), 5386-5389.
9. One-Pot Synthesis of Novel Photochromic Oxazine Compounds. Weili Zhao*, E. M. Carreira*, Org. Lett. 2011, 13 (19), 5084-5087.