黄青春博士,教授
个人简介
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黄青春，博士，教授。2001年毕业于南京农业大学植物保护学院，获植物病理学博士学位，同年进入华东理工大学工作至今。2003年-2007年兼任国家南方农药创制中心(上海)药效部主管，2011年-2012年美国普度大学访问****。现为中国生物化学与分子生物学会会员，上海市毒理学会理事。
主要从事杀菌剂生物学及新药创制研究，包括杀菌剂毒理及抗药性、植物病虫害化学防治等方面的研究。承担和参与了国家自然科学基金项目、国家重点基础研发项目、国家科技支撑计划项目、上海市科技攻关重点和重大项目、上海市“科技创新行动计划”生物医药领域和农业领域重点项目等研究。目前在J. Agric. Food Chem.、Pest Manag. Sci.、J. Phytopathol.、Pestic. Biochem. Physiol.、Crop Protection、Chemosphere、Ecotoxic. Environ. Saf.、农药学学报等国内外期刊发表学术论文70余篇，获得授权或公开的发明专利近20项。曾获得教育部自然科学一等奖1项，华东理工大学先进工作者称号。
研究方向
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方向一：杀菌剂及病害生物学研究。开展生物源的或化学仿生合成杀菌剂的高效筛选、作用机制及抗药性风险研究，探明农作物病害的杀菌剂防治技术。

方向二：新药研究。开展新型的具有杀菌或抗肿瘤活性的小分子药物的制备、衍生、及构效关系研究，阐明化合物抗菌或抗肿瘤的作用机制，探明活性药物在抗菌或抗肿瘤方面的潜在应用。

近期发表的研究成果
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Fungicidal effect of pyraclostrobin againstBotrytis cinereain relation to its crystal structure.
Hui Xiong, Xuefeng Liu, Jiuyong Xu, Xianfei Zhang, Shaorong Luan,Qingchun Huang^*.
Journal of Agricultural and Food Chemistry2020,68(39), 10975–10983.

Effect of membrane integrity on survival competition of Botrytis cinereaupon QoI fungicide pyraclostrobin.
Hui Xiong, Xuefeng Liu, Yuhang Fan, Shaorong Luan,Qingchun Huang^*.
Journal of Phytopathology2020, 168: 601–608.

Safety assessment of a new benzoylphenylurea TXH09 and its efficacy against two borers Ostrinia furnacalisand Grapholitha molestain field.
Hui Xiong, Xuefeng Liu, Jiuyong Xu, Xianfei Zhang, Song Cao,Qingchun Huang^*.
Ecotoxicology and Environmental Safety2020, 197: 110591.

Effect of 3-(2-pyridyl)methyl-2-(4-chlorphenyl)iminothiazolidine applied as a new fungicide against benzimidazole-resistant Sclerotinia sclerotiorum.
Xianfei Zhang, Jiuyong Xu, Solange Muhayimana, Hui Xiong, Yufan Xue,Qingchun Huang^*.
Pest Management Science 2020,76: 2978–2985.

Efficient determination of trace thionyl chloride in the antiepileptic levetiracetam by pyrolysis combined with ion chromatography.
Shaorong Luan, Pengyu Liu, Fangfang Zhang, Lijun Ni,Qingchun Huang.
Chromatographia2020, 83,1391–1395.

Comparative cytotoxic effects of five commonly used triazole alcohol fungicides on human cells of different tissue types.
Jiuyong Xu, Hui Xiong, Xianfei Zhang, Solange Muhayimana, Xuefeng Liu, Yufan Xue, andQingchun Huang^*.
Journal of Environmental Science and Health B.2020,55(5): 438–446.

Field-scale evaluation on the efficacy of a novel benzoylphenylurea TXH09 against chewing insect pests harming vegetables and rice.
Xianghu Zhao,Chunmei Li,Jiuyong Xu, Xianfei Zhang, Hui Xiong,Qingchun Huang^*,Song Cao^*.
Crop Protection2019, 126: 104925.

Cytotoxic selectivity and apoptosis induction of piericidin A contributes potentially to its insecticidal effect against Mythimna separata(Lepidoptera: Noctuidae) larvae.
Solange Muhayimana, Xianfei Zhang, Jiuyong Xu, Hui Xiong, Shaorong Luan^*, Qiqi Zhu,Qingchun Huang^*.
Pesticide Biochemistry and Physiology2019, 157: 19–25.

The effect of α-tocopherol and dithiothreitol in ameliorating emamectin benzoate cytotoxicity in human K562 cells involving the modulation of ROS accumulation and NF-κB signaling.
Shaorong Luan, Solange Muhayimana, Jiuyong Xu, Xianfei Zhang, Ciying Xiao,Qingchun Huang^*.
Ecotoxicology and Environmental Safety2019, 167: 114–121.

Photosensitizationof Chinese hamster V79 cells to photoactivatedalpha terthienyl involving membrane damage and oxidative stress.
Shaorong Luan, Solange Muhayimana, Jiuyong Xu, Xianfei Zhang, Ciying Xiao,Qingchun Huang^*.
Journal of Photochemistry and Photobiology B: Biology2018, 185: 192–198.

Purification and biochemical characterization of a novel transglutaminase from Mythimna separatalarvae (Noctuidae, Lepidoptera).
Lei Zhang, Wenbing Rao, Solange Muhayimana, Xianfei Zhang, Jiuyong Xu, Ciying Xiao,QingchunHuang^*.
Journal of Biotechnology2018, 265: 1–7.

Tolerance potential of Chilo suppressalislarvae to fipronil exposure via the modulation of detoxification and GABA responses.
Ciying Xiao,Shaorong Luan,Zhikang Xu, JialingLang, Wenbing Rao,QingchunHuang^*.
Journal of Asia-Pacific Entomology2017, 20: 1287–1293.

A comparative assessment of cytotoxicity of commonly used agricultural insecticides to human and insect cells.
Xinming Yun,QingchunHuang^*, Wenbing Rao, Ciying Xiao, Tao Zang, Zhifan Mao, Ziyi Wan.
Ecotoxicology and Environmental Safety2017, 137: 179–185.

Emamectin benzoate induces ROS-mediated DNA damage and apoptosis in Trichoplusia Tn5B1-4 cells.
Shaorong Luan,WenbingRao, Xinming Yun, Ciying Xiao, Zhikang Xu,Jialing Lang,QingchunHuang^*.
Chemico-Biological Interactions2017, 273: 90–98.

Antioxidative cellular response of lepidopteranovariancellsto photoactivated alpha-terthienyl.
QingchunHuang^*,Xinming Yun, Wenbing Rao, Ciying Xiao.
Pesticide Biochemistry and Physiology2017, 137: 1–7.

Apoptosis of leukemia K562 and Molt-4 cells induced by emamectin benzoate involving mitochondrial membrane potential loss and intracellular Ca²⁺modulation.
Xinming Yun, Wenbing Rao, Ciying Xiao,QingchunHuang^*.
Environmental Toxicology and Pharmacology2017, 52: 280–287.

The competence of hemocyte immunity in the armyworm Mythimna separatalarvae to sublethal hexaflumuron exposure.
QingchunHuang^*, Lei Zhang, Chao Yang, Xinming Yun, Yuan He.
Pesticide Biochemistry and Physiology2016, 130: 31–38.

Detection on emamectin benzoate-induced apoptosis and DNA damage in Spodoptera frugiperdaSf9 cell line.
Xiwei Wu, Lei Zhang, Chao Yang, Mimi Zong,QingchunHuang*, et al.
Pesticide Biochemistry and Physiology2016, 126: 6–12.

Design and synthesis of thiourea derivatives with sulfur-containing heterocyclic scaffolds as potential tyrosinase inhibitors.
Pingping Liu, C Shu, L Liu,QingchunHuang, Yanqing Peng.
Bioorganic and Medicinal Chemistry2016,24: 1866–1871.

Suppression of carbendazim-susceptible and -resistant Sclerotinia sclerotiorumwith Macleya alkaloids.
QingchunHuang*, Xiwei Wu, Xiaoqin Yu,et al.
Archives of Phytopathology and Plant Protection2015,48(6): 485–494.

The organophosphate insecticide chlorpyrifos confers its genotoxic effects by inducing DNA damage and cell apoptosis.
Diqiu Li,QingchunHuang*, Miaoqing Lu, Lei Zhang, et al.
Chemosphere2015, 135: 387–393.

Synergistic effect of nonionic surfactants Tween 80 and PEG6000 on cytotoxicity of insecticides.
Diqiu Li, XiweiWu, Xiaoqin Yu,QingchunHuang*, et al.
Environmental Toxicology and Pharmacology2015, 39: 677–682.

Comparison of the cytotoxic impact of chlorfluazuron on selected insect and human cell lines.
QingchunHuang*, Xiwei Wu, Xiaoqin Yu, Lei Zhang, et al.
Environmental Toxicology and Chemistry2015, 34: 1675–1682.

授权和公开发明专利
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喹唑啉基羧酸酯类化合物及其用途.0.3
亚氨基噻唑烷类化合物的新用途.3.0
分离纯化昆虫谷氨酰胺转氨酶的方法.1.5
一种新型昆虫细胞免疫抑制剂的用途.1.0
用于制备昆虫神经元细胞的生理缓冲液、消解液及方法.9.0
阿维菌素B1a荧光标记物及其应用.7.1
用于检测油菜菌核病菌的方法和培养基.8.5
含七氟异丙基苯甲酰脲类化合物及其用途.B
含2’-羟基六氟异丙基的邻苯二甲酰胺类化合物及其用途.
新型3-硒代吲哚的合成对植物生长促进和富硒作用.B
含二氟(亚)甲基邻甲酰胺基苯甲酰胺类化合物.A
具有杀虫活性的含氮杂环化合物、其制备及用途.PCT/CN2008/071115
一类具有高杀虫活性化合物的制备方法及用途.PCT/CN 2006/000360
唑酰胺类化合物及其制备和应用.8.8
一类新型3-硒代吲哚的合成对植物生长促进和富硒作用.7. 1
一种噁唑哒嗪及其衍生物的剂型与应用.4.1
哌嗪衍生物及其用途.1.6
腺苷衍生物及其用途.2.X
Nitrogenous heterocyclic compounds with insecticidal activity, and the preparation and use thereof. 美国专利US 12/864,410
Benzoylurea compounds bearing heptafluoroisopropyl and uses thereof. PCT专利WO/2009/115040 A1
硝基亚甲基衍生物及其用途.PCT/CN2005/000617，WO**.7，US11/751,836，EP**A1，JP2007-541642
联系方式
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地址: 上海市徐汇区梅陇路130号 华东理工大学 药学院
电话:
E-mail: qchuang@ecust.edu.cn