邵旭升，教授，博士生导师
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传真:
E-mail: shaoxusheng@ecust.edu.cn
个人简介
邵旭升：博士，教授，博士生导师。2009年7月毕业于华东理工大学应用化学专业，导师李忠教授。2012年至2013年在美国加州大学伯克利分校John E. Casida教授课题组进行农药的毒理、代谢和作用机制研究。主要研究方向为绿色农药创制与应用、光药理学、杀虫剂作用的生物学机制。在PNAS、J. Agric. Food Chem.、Insect Biochem. Mol. Biol.等杂志发表SCI论文80多篇，其中第一或通讯作者论文40多篇；申请国内外专利50多项，获中国专利授权6项，国外专利授权21项；是新烟碱杀虫剂哌虫啶和环氧虫啶的主要发明人；国内外重大学术会议邀请报告20多次；获中国专利优秀奖、中国农药工业协会农药创新贡献奖-技术创新奖一等奖和二等奖各一项，入选上海市浦江人才计划和校青年英才计划，获上海市优秀博士论文以及上海市科创杯一等奖2次。作为项目负责人承担国家重点研发计划子课题、国家自然科学基金、上海市科技创新行动计划，澳大利亚DC研究基金等多项科研项目。
研究方向
1. 绿色农药创制
2.光药理学
3. 农药毒理学
4. 合成方法学
发表论文

Xusheng Shao, Xuhong Qian, Zhong Li, Xiaoyong Xu, Philip W. Lee. Current situation for research and development of novel pesticides in China. In Trend in Pesticide Discovery Research-Development of Safer and Environmentally Friendly Pesticides. Noriharu Umetsu, eds. 2018. (Book Chapter)
Qingqing Hou, Yifei Jing, Xusheng Shao. Synthesis and insecticidal activities of 1,8-naphthyridine derivatives.Chin. Chem. Lett.2017, 28, 1723-1726.
Zhenhong Gao, Yifei Jing, Donghui Wang, Zhiping Xu, Zhong Li, Xusheng Shao*.Photo-controlled Release of Fipronil from a Coumarin Triggered Precursor. Bioorg. Med. Chem. Lett. 2017, 27, 2528-2535.
Yanan Zhang, Yian Feng, Zhong Li, Xusheng Shao*.Synthesis and Insecticidal Evaluation of Phytoalexin Phenalenones Derivatives. Chin. Chem. Lett.2017, 28, 1228-1231.
Xue Tian, Chao Zhang, Qi Xu, Zhong Li and Xusheng Shao*. Azobenzene-Benzoylphenylureas as Photoswitchable Chitin Synthesis Inhibitors. Org. Biomol. Chem.2017, 15, 3320-3323.
Runjiang Song, Yian Feng, Donghui Wang, Zhiping Xu, Zhong Li, Xusheng Shao*. Phytoalexin Phenalenone Derivatives Inactivate Mosquito Larvae and Root-knot Nematode as Type-ⅡPhotosensitizer. Sci. Rep.2017, 7, 42058.
Ye Liu, Xinfei Chen, Xiaoyong Xu, Jiagao Cheng, Xusheng Shao*, and Zhong Li* Design, Synthesis and Insecticidal Activity of Diamides with Oxydibenzene or Diphenylamine Subunits. Lett. Drug Des. Discov. 2017, 14, 262-269.
Yian Feng, Minming Zou, Runjiang Song, Xusheng Shao*,Zhong Li, Xuhong Qian. Formation of 1,4,2-Dithiazolidines or 1,3-Thiazetidines from 1,1-Dichloro-2-nitroethene and Phenylthiourea Derivatives. J. Org. Chem.2016, 81, 10321-10327.
Shen Li, Runjiang Song, Donghui Wang, Xue Tian, Xusheng Shao*,Zhong Li. Azopyridine-imidacloprid derivatives as photoresponsive neonicotinoids. Chin. Chem. Lett.2016, 27, 635-639.
Feilong Sun, Xusheng Shao*, Zhong Li. Access of Indenofurans and Indenopyridines via Annulation of Heterocyclic Ketene Aminals, o-Phthalaldehyde and cyclic 1.3-diketones. RSC Advance2016, 6, 15382-15389.
Fengjuan Zhu, Runjiang Song, Shen Li, Xusheng Shao*. In-water Synthesis of Quinazolinones from 1,1-Dichloro-2-nitroethene and Anthranilamides. Synlett 2016, 27, 2167-2170.
Ye Liu, Chao Lei, Xiaoyong Xu, Xusheng Shao*, Zhong Li*. Design, synthesis and insecticidal activity of biphenyl-diamide derivatives, Chin. Chem. Lett.2016, 27, 321-324.
Jiling Li, Dang Wu, Xiaoyong Xu, Jin Huang, Xusheng Shao* and Zhong Li*. Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1, 3-benzoazole derivatives bearing amide units. Bioorg. Med. Chem. Lett.2016, 26, 3064-3066.
Fengjuan Zhu, Xue Tian, Xusheng Shao*, Zhong Li. Direct Amidation of Aniline Derivatives with 1,1-Dichloro-2-nitroethene in Water. Tetrahedron Lett. 2015, 56, 5945-5949.
Zhiping Xu, Lina Shi, Danping Jiang, Jiagao Cheng, Xusheng Shao*, Zhong Li. Azobenzene Modified Imidacloprid Derivatives as Photoswitchable Insecticides: Steering Molecular Activity in a Controllable Manner. Sci. Rep.2015, 5, 13962.
Fengjuan Zhu, Minming Zou, Xusheng Shao*, Zhong Li. On-water, Catalyst-Free and Room-temperature Construction of 2-Aryl-1,3,4-oxadiazole Derivatives from 1,1-Dichloro-2-nitroethene and Hydrazides. RSC Advance2015, 5, 61752-61758.
Feilong Sun, Fengjuan Zhu, Xusheng Shao*, Zhong Li. One-pot and Three-components Synthesis of 1,8-Naphthyridine Derivatives from Heterocyclic Ketene Aminals, Malononitrile Dimer and Aryl Aldehydes. Synlett 2015, 26, 2306-2312.
Nanyang Chen, Xiaoqing Meng, Fengjuan Zhu, Jiagao Cheng, Xusheng Shao*, Zhong Li. Tetrahydroindeno[1’,2’:4,5]pyrrolo[1,2-a]imidazol-5(1H)-ones as Novel Neonicotinoid Insecticides: Reaction Selectivity and Substituent Effects on the Activity Level. J. Agric. Food Chem. 2015, 63, 1365-1369.
Jiling Li, Zhicheng Zhang, Xiaoyong Xu, Xusheng Shao*, Zhong Li*. Nematicidal Activities of Diamides with Diphenylacetylene Scaffold against Meloidogyne Incognita. Aust. J. Chem.2015, 68, 1543-1549.
Jiling Li, Xiaoyong Xu, Xusheng Shao*, Zhong Li*. A Novel Colorimetric Fluoride Sensor Based on a Semi-rigid Chromophore Controlled by Hydrogen Bonding, Luminescence, 2015, 30, 1285-1289.
Minming Zou, Xue Tian, Nanyang Chen, Xusheng Shao*. Nematicidal Activity of Sprio and Bridged Heterocyclic Neonicotinoid Analogues against Meloidogyne incognita. Lett. Drug Des. Discov.2015, 12, 439-445.
Yefeng Fan, Song Liu, Nanyang Chen, Xusheng Shao*, Xiaoyong Xu, Zhong Li*. Oxidation strategy for the synthesis of regioisomeric spiroisobenzofuranopyrroles: facile entries to spiro[isobenzofuran-1,2’-pyrrole] and spiro[isobenzofuran-1,3’-pyrrole] derivatives. Synlett 2015, 26, 393-403.
Nanyang Chen, Shanshan Xia, Minming Zou, Xusheng Shao*. Bridged heterocyclic neonicotinoid analogues: design, synthesis, and insecticidal activity. Res. Chem. Intermed. 2015, 41, 5293-5300.
Minming Zou, Nanyang Chen, Liping Ren, Xusheng Shao*, Zhong Li. A novel and facile synthesis of 2-oxo-1,2-dihydropyridine-fused 1,3-diazaheterocycles via heterocyclic ketene aminals and Knoevenagel adducts formed by phthalic anhydride and ethyl cyanacetate. Chin. Chem. Lett. 2014, 25, 1515-1519.
Nanyang Chen, Minming Zou, Xue Tian, Fengjuan Zhu, Danping Jiang, Xusheng Shao*, Zhong Li*Isomerization of Ninhydrin-Heterocyclic Ketene Aminals Adducts: Kinetic versus Thermodynamic Control, Solvents Dependency and Mechanism.Eur. J. Org. Chem. 2014, 28, 6210-6218.
Nanyang Chen, Liping Ren, Zhiping Xu, Minming Zou, Xusheng Shao*, Xiaoyong Xu, Zhong Li*. Design, Synthesis and Insecticidal Activity of Spiro Heterocycle Containing Neonicotinoid Analogues. Chin. Chem. Lett. 2014, 25, 197-200.
Jingwei Zhang, Xusheng Shao*, Zhong Li, Xiaoyong Xu. Bis-phenylazoneonicotinoids as Divalent Insecticides: Design, Synthesis and Activity. Lett. Drug Des. Discov.2014, 11,150-155.
Liping Ren, Yanpeng Lou, Nanyang Chen, Shanshan Xia, Xusheng Shao*, Xiaoyong Xu, Zhong Li. Synthesis and Insecticidal Activities of Tetrahydroimidazo[1,2-a]pyridinones: Further Exploration on cis-Neonicotinoids. Synthetic Commun. 2014, 44, 858-867.
Xusheng Shao*, Shanshan Xia, Kathleen A. Durkin, John E. Casida*. Insect Nicotinic Receptor Interactions in Vivowith Neonicotinoid, Organophosphorus and Methylcarbamate Insecticides and a Synergist. Proc. Natl. Acad. Sci. U.S.A. 2013, 110, 17273–17277.
Xusheng Shao, Tami L. Swenson, John E. Casida*. Cycloxaprid Insecticide: Nicotinic Acetylcholine Receptor Binding Site and Metabolism. J. Agric. Food Chem. 2013, 61, 7883–7888.
Xusheng Shao, Zewen Liu, Xiaoyong Xu, Zhong Li*, Xuhong Qian. Overall Status of Neonicotinoid Insecticides in China: Production, Application and Innovation. J. Pestic. Sci.2013, 38, 1–9.
Xusheng Shao*, Xinglong Huang, Qian Shi, Zhong Li, Liming Tao, Gonghua Song*. Synthesis and Insecticidal Activities of Chlorothiazolyl Analogues of Nitromethylene Neonicotinoids with Tetrahydropyridine Fixed cis-Configuration. J. Heterocycl. Chem.2012, 49, 1136–1142.
Xusheng Shao, Zhenjun Ye, Haibo Bao, Zewen Liu, Xiaoyong Xu, Zhong Li*, Xuhong Qian*. Advanced research on cis-neonicotinoids. Chimia2011, 65, 957–960.
Xusheng Shao, Hanyan Liu, Haibo Bao, Xiaoyong Xu, Zewen Liu, Zhong Li*. The Mode of Action of a Nitroconjugated Neonicotinoid and the Effects of Target Site Mutation Y151S on its Potency. Insect Biochem. Mol. Biol.2011, 41, 440–445.(Insect Biochemistry and Molecular Biology),
Xusheng Shao, Philip W. Lee, Xiaoyong Xu, Zewen Liu, Zhong Li*, Xuhong Qian. cis-Configuration: A New Tactic/Rationale for Neonicotinoid Molecular Design. J. Agric. Food Chem. 2011, 59, 2943–2949.
Xusheng Shao, Hua Fu, Xiaoyong Xu, Xinglei Xu, Zhong Li*, Zewen Liu. Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid: Design, Synthesis, Crystal Structure and Insecticidal Activities. J. Agric. Food Chem.2010,58, 2696–2702.
Xusheng Shao, Zhiping Xu, Xianfeng Zhao, Xiaoyong Xu, Liming Tao, Zhong Li*, Xuhong Qian*. Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities.J. Agric. Food Chem.2010,58, 2690–2695.