徐志爱 教授 博导
化学与分子工程学院??????


导航
个人资料
研究方向
开授课程
科研项目
学术成果
荣誉及奖励







个人资料
部门： 化学与分子工程学院
毕业院校： 中国科学院
学位： 分析化学
学历： 博士
邮编： 200241
联系电话：
传真：
电子邮箱： zaxu@chem.ecnu.edu.cn
办公地址： 化学楼335室
通讯地址： 上海市东川路500号

教育经历
2001年9月－2006年12月，中国科学院长春应用化学研究所，博士


工作经历
2018年1月－至今：华东师范大学教授
2012年5月－2017.12：华东师范大学副教授
2009年6月－2012年4月：助教授，东北大学，日本(Tohoku University, Japan)。
2007年6月－2009年5月：日本学术振兴会（JSPS）博士后研究员，东北大学，日本(Tohoku University, Japan)。



个人简介

社会兼职


研究方向
研究经历
2018.1--至今，华东师范大学，化学与分子工程学院，教授；
2012.5--2017.12，华东师范大学，化学与分子工程学院，副教授；

2009.6--2012.4，日本东北大学，理学院，助教授；
2007.6--2009.5，日本东北大学，理学院，JSPS博士后，导师：Norio Teramae教授；
2001.9--2006.12，中科院长春应用化学研究所，电分析化学国家重点实验室，直博，获博士学位，导师：董绍俊 研究员
研究方向
生物大分子的组装及在生物分析中的应用
荧光探针的合成和生物分析应用
神经退行性疾病相关分析检测


开授课程
分析化学与分析技术I
分析化学与分析技术I实验
分析化学与分析技术II实验



科研项目
国家自然科学基金面上项目 2017-2020
国家自然科学基金青年项目 2014-2016



学术成果
代表性研究论文：

[1]Y. Lai, Z. Xu,* X. Hu, L. Lei, L. Li, L. Dong, H. Yu,* W. Zhang*. Peptide Nanotube-Templated Biomineralization of Cu2-xS Nanoparticles for Combination Treatment of Metastatic Tumor. Small 2019,**.
[2]L. Lei, R. Geng, Z. Xu,* Y. Dang, X. Hu, L. Li, P. Geng, Y. Tian, W. Zhang*. Glycopeptide Nanofiber Platform for Ab-Sialic Acid Interaction Analysis and Highly Sensitive Detection of Ab. Anal. Chem. 2019, 91, 8129-8136.
[3]R. Geng, D. Lu, Y. Lai, S. Wu, Z. Xu* and W. Zhang*, Peptide nanotube for carbon dioxide chemisorption with regeneration properties and water compatibility. Chem. Commun. 2019, 55, 3797-3800.
[4]L. Lei, Z. Xu*, X. Hu, Y. Lai, J. Xu, B. Hou, Y. Wang, H. Yu*, Y. Tian, W. Zhang*. Bioinspired Multivalent Peptide Nanotubes for Sialic Acid Targeting and Imaging-Guided Treatment of Metastatic Melanoma. Small 2019, 15(22), **.
[5]F. Wang, S. Yu, Z. Xu, * L. Li, Y. Dang, X. Xu, Y. Luo, Z. Cheng, H. Yu, W. Zhang, A. Zhang, and C. Ding*. Acid-Promoted D-A-D Type Far-Red Fluorescent Probe with High Photostability for Lysosomal Nitric Oxide Imaging, Anal. Chem. 2018, 90 (13), 7953-7962.
[6]F. Lin, Y. Zhou, Q. Li, X. Zhou, Y. Shao,^* B. Habermeyer, H. Wang, X. Shi, and Z. Xu,^*Prototropically Allosteric Probe for Superbly Selective DNA Analysis, Anal. Chem. 2017,89 (17), 9299–9306.
[7]F. Wang, C. Feng, Z. Xu,^*W. Zhang,^*A ratiometric fluorescent probe for rapid and sensitive detection of biothiols in fetal bovine serum, Talanta,2017, 169, 149-155.
[8]C. Feng, F. Wang, Y. Dang, Z. Xu,^* H. Yu, and W. Zhang. A Self-Assembled Ratiometric Polymeric Nanoprobe for Highly Selective Fluorescence Detection of Hydrogen Peroxide, Langmuir, 2017, 33, 3287–3295.
[9]Y. Hu, F. Lin, T. Wu, Y. Zhou, Q. Li, Y. Shao,^*Z. Xu,^* DNA Duplex Engineering for Enantioselective Fluorescent Sensor, Anal. Chem., 2017, 89, 2181-2185.
[10]L. Lu, C. Feng, J. Xu, F. Wang, H. Yu, Z. Xu,^* W. Zhang, Hydrophobic-carbon-dot-based dual-emission micelle for ratiometric fluorescence biosensing and imaging of Cu2+ in liver cells, Biosensors and Bioelectronics, 2017, 92, 101-108.
[11]F. Wang, ? Q. Sun, ? B. Feng, Z. Xu, ^* J. Zhang, J. Xu, L. Lu, H. Yu, M. Wang, Y. Li and W. Zhang*, Polydopamine-Functionalized Graphene Oxide Loaded with Gold Nanostars and Doxorubicin for Combined Photothermal and Chemotherapy of Metastatic Breast Cancer, Adv. Healthc. Mater., 2016, 5, 2227–2236.
[12]J. Zhang, J. Liu, Y. Zhu, Z. Xu, ^*J. Xu, T. Wang, H. Yu and W. Zhang^*, Photodynamic micelles for amyloid β degradation and aggregation inhibition, Chem. Commun., 2016, 52, 12044-12047.
[13]B. Feng?, F. Zhou?, Z. Xu? (first coauthor), T. Wang, D. Wang, J. Liu, Y. Fu, Q. Yin, Z. Zhang, H. Yu,* and Y. Li*, Versatile Prodrug Nanoparticles for Acid-Triggered Precise Imaging and Organelle-Specific Combination Cancer Therapy. Adv. Funct. Mater. 2016, 26,7431–7442.
[14]Y. Wang, L. Lu, H.Peng, J. Xu, F. Wang, R. Qi, Z. Xu* and W. Zhang*, Multi-doped carbon dots with ratiometric pH sensing properties for monitoring enzyme catalytic reactions. Chem. Commun., 2016, 52, 9247-9250.
[15]L. Zhu, J. Zhang, F. Wang, Y. Wang, L. Lu, C. Feng, Z. Xu*, W. Zhang*. Selective amyloid β oligomer assay based on abasic site-containing molecular beacon and enzyme-free amplification, Biosensors and Bioelectronics, 2016,78, 206-212.
[16]Y. Wang, J. Zhang, L. Zhu, L. Lu, C. Feng, F. Wang, Z. Xu* and W. Zhang*. Activation of Mg2+-dependent DNAzymes based on AP site-containing triplex for specific melamine recognition. Analyst, 2015, 140, 7508-7512.
[17]B. Feng?, Z. Xu? (first coauthor), F. Zhou, H. Yu, Q. Sun, D. Wang, Z. Tang, H. Yu, Q. Yin, Z. Zhang and Y. Li. Near infrared light-actuated gold nanorods with cisplatin–polypeptide wrapping for targeted therapy of triple negative breast cancer. Nanoscale, 2015, 7, 14854-14864
[18]Y. Wang, Q. Sun, L. Zhu, J. Zhang, F. Wang, L. Lu, H. Yu, Z. Xu* and W. Zhang*. Triplex molecular beacons for sensitive recognition of melamine based on abasic-site-containing DNA and fluorescent silver nanoclusters. Chem. Commun.,2015, 51, 7958-7961.
[19]B. Lin, D. Lu, Y. Fu, Q. Sun, K. Liu, Z. Xu* and W. Zhang*. Label-free Colorimetric Protein Assay and Logic Gates Design Based on the Self-assembly of Hemin-Graphene Hybrid Nanosheet.Langmuir, 2014, 30(8), 2144-251.
[20]Y. An, Y. Fu, D. Lu, Y. Wang, W. Bi, Z. Xu,* S. Dong, S. Zhang, C. Wang and W. Zhang*. A TiO2-Au–polymer hybrid system for the photoelectrochemical immunoassay of SirT1. J. Mater. Chem. B, 2014, 2, 1644-1652.
[21]Y. Fu, K. Liu, Q. Sun, B. Lin, D. Lu, Z. Xu*, Chen Hu, G. Fan, S. Zhang, C. Wang, W. Zhang*. A highly sensitive immunosensor for calmodulin assay based on enhanced biocatalyzed precipitation adopting a dual-layered enzyme strategy. Biosensors and Bioelectronics, 2014, 56, 258-263.






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