肖元晶 副教授副教授
化学与分子工程学院??????


导航
个人资料
研究方向
开授课程
科研项目
学术成果
荣誉及奖励







个人资料
部门： 化学与分子工程学院
毕业院校： 武汉大学
学位： 博士
学历： 研究生
邮编： 200241
联系电话：
传真： **
电子邮箱： yjxiao@chem.ecnu.edu.cn
办公地址： 华东师大闵行校区化学楼523
通讯地址： 上海市闵行区东川路500号华东师范大学化学与分子工程学院

教育经历
1993.09-1997.07 湖北大学化学与材料科学学院 理学学士
1997.09-2002.07 武汉大学化学与分子科学学院 理学博士



工作经历
2002.09-至今 华东师范大学化学与分子工程学院
2011.10-2012.10美国加州大学圣巴巴拉分校访问****



个人简介

社会兼职
Journal of Heterocyclics (ISSN 2639-6734)，编委


研究方向
多样性导向有机合成方法学研究, 新型催化剂的设计与开发，不对称催化，新型含氟砌块的设计与转化研究


开授课程
主讲本科生专业必修课：有机化学（II）， 有机化学实验
辅导本科生参加上海市及全国师范类化学实验竞赛


科研项目
国家自然科学基金项目：
学术成果
代表性论文：
27.Anjing Hu, Zhan-Ming Zhang,Yuanjing Xiao*, Junliang Zhang*Stereoselective Synthesis of Chiral Sulfinamide Monophosphine Ligands (Ming-Phos)(S, Rs)-M.Org. Synth. 2020, 97, 262-273.



26.Yi Wu, Yuanjing Xiao*, Junliang Zhang*BCl3 Mediated Borylative Cyclization of 2-(1-alkynyl)-2-alken-1-ones.
Chin. J. Org. Chem. 2020, 40.cjoc.R1.



25.HuayuCheng,XiaofanZhou,AnjingHu,ShitengDing,YimoWang,YuanjingXiao*,JunliangZhang*Thioether-Functionalized Trifluoromethyl-alkynes, 1, 3-Dienes and Allenes: DivergentSynthesisfrom Reaction of 2-Trifluoromethyl-1, 3-Conjugated Enynes with Sulfur Nucleophiles.RSC Adv., 2018, 8, 34088–34093.


24.Qin Zeng, Li Zhang,Yuanjing Xiao* and Junliang Zhang* Divergent Access to N-Hydroxypyrroles and Isoxazoles via Gold(I)- or Br?nsted Acid- Catalysed Regioselective Cyclization of N-(2-trifluoromethyl-3-Alkynyl) Oximes.Org. Biomol. Chem., 2018,16，1375-1380。


23.Chaoqian Huang, Yu Zeng, Huayu Cheng, Anjing Hu, Lu Liu, Yuanjing Xiao, ^*and Junliang Zhang^*AOne-Pot Construction of Halogenated Trifluoromethylated Pyrrolesthrough NXS (X =Br, I) Triggered Cascade.Org. Lett.,2017,19, 4968-4971.


22.Yu Zeng,Chaoqian Huang,Peiyun Ni,Lu Liu,Yuanjing Xiao*and Junliang Zhang*Silver-Catalyzed Double Hydrocarbonation of 2-Trifluorometh- yl-1,3-Conjugated Enynes with 1,3-Dicarbonyl Compounds: Synthesis ofRing-Trifluoromethylated Cyclopentene.Adv. Synth. Catal.2017, 359, 3555-3559.



21.Jieru Yang,Xiaofan Zhou,Yu Zeng,Chaoqian Huang,Yuanjing Xiao*andJunliang Zhang*Divergent Synthesisfrom Reactions of 2-Trifluoromethyl-1,3-Conjugated EnyneswithN-Acetylated2-Aminomalonates.
Org. Biomol. Chem., 2017,15, 2253-2258.

20. Xiaofan Zhou, Chaoqian Huang, Yu Zeng, Jiarui Xiong, Yuanjing Xiao*and Junliang Zhang*, Silver-Catalysed Tandem Hydroamination and Cyclization of 2-Trifluoromethyl-1,3-Enynes with Primary Amines:A Modular Entry to 4-Trifluoromethyl-3-Pyrrolines.Chem. Commun.,2017, 53, 1084-1087.


19.Bing Xu,Zhan-Ming Zhang,Shan Xu, Bing Liu, Yuanjing Xiaoand Junliang Zhang*Copper(I)/Ming-Phos-Catalyzed Asymmetric Intermolecular [3+2] Cycloaddition of Azomethine Ylides with a-Trifluoromethyl a, b-Unsaturated Esters.ACS Catal.2017, 7, 210?214.



18.Jieru Yang, Xiaofan Zhou, Yu Zeng, Chaoqian Huang, Yuanjing Xiao^*and Junliang Zhang^*Synthesis of 2-fluoro-2-pyrrolines via tandem reaction of α-trifluoromethyl-α,β-unsaturatedcarbonyl compounds with N-tosylated2-aminomalonates. Chem.Commun., 2016, 52, 4922.



17.Yanqing Zhang, Yuanjing Xiao*and Junliang Zhang*. Gold(I)-Catalyzed Stereospecific [4+3] Cycloaddition Reaction of Optically Active 1-(1-alkynyl)cyclopropyl Ketone with Nitrones: A Modular Entry to Enantioriched 5,7-Fused Bicyclicfuro[3,4-d]-[1,2]oxazepines.Synthesis, 2016, 48, 512(Feature Article).



16.Peng Chen, Xiao Su, Wei Zhou,Yuanjing Xiao*and Junliang Zhang*. Novel Chiral Sulfinamide Phosphines : Valuable Precursors to Chiral β-Aminophosphines. Tetrahedron,2016, 72,2700.


15.Jieru Yang, Ao Mao, Zhenting Yue, Wenxuan Zhu, Xuewei Luo, Chuwei Zhu,Yuanjing Xiao^*and Junliang Zhang^* A simple base-mediated synthesis of diverse functionalized ring-fluorinated 4H-pyranvia double direct C-F substitutions^?Chem.Commun,2015, 51, 8326.


14.Ziqi Tian, Yuanjing Xiao, Xianggai Yuan, Zuliang Chen, Junliang Zhang^* and Jing Ma^*.Control of Chemoselectivity by Coordinated Water and Relative Size of Ligands to Metal Cations of Lewis Acid Catalysts for Cycloadditionof an Oxirane Derivative to an Aldehyde: Theoretical and Experimental Study. Organometallics. 2014, 33, 1715.



13.Li Zhang, Qin Zeng, Ao Mao, Ziang Wu, Tian Luo, Yuanjing Xiao^*and Junliang Zhang^*. NIS-mediated oxidative cyclization of N-(2-trifluoromethyl-3-alkynyl)hydroxylamines:a facile access to 4-trifluoromethyl-5-acylisoxazoles.Org.Biomol. Chem.2014, 12, 8942.


12.Qin Zeng, Li Zhang, Jieru Yang, Bing Xu, Yuanjing Xiao^*and Junliang Zhang^*. Pyrroles versusCyclic Nitrones: Catalyst-Controlled Divergent Cyclization of N-(2-perfluoroalkyl-3-alkynyl) hydroxylamines.Chem. Commun. 2014, 50,4203.


11.JunqingZhang, Yuanjing Xiaoand Junliang Zhang^*. Nickel-Catalyzed Annulation of Donor–Acceptor Oxiranes with Imines: Diastereoselective Access to Highly Substituted 2,4-trans- Oxazolidines. Adv. Synth. Catal.2013, 355, 2793.


10. ZuliangChen, Yuanjing Xiaoand Junliang Zhang^*. Reaction of Two Differently Functionalized Oxiranes with Nickel Perchlorate :A Modular Entry to Highly Substituted 1,3-Dioxolanes. Eur. J. Org. Chem.2013, 4748.


9.Yuanjing Xiaoand Liming Zhang^*. Synthesis of Bicyclic Imidazoles via [2 + 3] Cycloaddition between Nitriles and Regioselectively Generated α-Imino Gold Carbene Intermediates.Org. Lett., 2012, 14(17), 4662.


8.Ze-Yi Yan,Yuanjing Xiaoand Liming Zhang^*. Gold-Catalyzed One-Step Construction of 2,3-Dihydro-1H-Pyrrolizines with an Electron-Withdrawing group in the 5-position: A Formal Synthesis of 7-Methoxymitosene. Angew. Chem. Int. Ed. 2012, 51, 8624.


7. Yuanjing Xiao? Junliang Zhang^*. Tetrasubstituted Allenes by Pd⁰-Catalyzed Three-Component Tandem Michael Addition / Cross-Coupling Reaction.Chem. Commun. 2010?46? 752.


6. Yuanjing Xiao? Junliang Zhang^*. Pd(II)-Catalyzed Domino Reaction of 2-(1-Alkynyl)-2-alken-1-ones with Nucleophiles: Scope? Mechanism and Synthetic Application in the Synthesis of 3?4-Fused Bicyclic Tetrasubstituted Furans.Adv. Synth. Catal. 2009? 351? 617.

5.Yuanjing Xiao? Junliang Zhang^*. Furan versus 4H-Pyran: Catalyst-Controlled Regiodivergent Tandem Michael Addition/Cyclization Reaction of 2-(1-Alkynyl)-2-alken-1-ones with 1?3-Dicarbonyl Compounds. Chem. Commun. 2009? 3594.


4.Yanqing Zhang? Zuliang Chen? Yuanjing Xiao? Junliang Zhang^*. Rh^I-Catalyzed Regio- and Stereospecific Carbonylation of 1-(1-Alkynyl)cyclopropyl Ketones: A Modular Entry to Highly Substituted 5?6-Dihydrocyclopenta[c]furan-4-ones.Chem. Eur. J. 2009? 15? 5208.


3. Wenbo Li? Yuanjing Xiao? Junliang Zhang^*. Alkynyl Group as Activating Group: Base-Catalyzed Diastereo-selective Domino Reactions of Electron-Deficient Enynes. Adv. Synth. Catal. 2009? 351? 3083.


2. Yuanjing Xiao? Junliang Zhang^*. Tetrasubstituted Furans by a Pd(II)-Catalyzed Three-Component Michael Addition /Cyclization /Cross-Coupling Reaction. Angew. Chem. Int. Ed. 2008? 47? 1903.


1. Xiuzhao Yu?Hongjun Ren?Yuanjing Xiao? Junliang Zhang^*. Efficient Assembly of Allenes? 1?3-Dienes? and 4H-Pyrans by Catalytic Regioselective Nucleophilic Addition to Electron-Deficient 1?3-Conjugated Enynes. Chem. Eur. J. 2008? 14? 8481.


撰写专著：
(1) Junliang Zhang? Yuanjing Xiao"Cyclization of cyclopropane and cyclopropnene-contaninng compounds" in "Handbook of Cyclization Reactions"(Eds. Shengming Ma)? Willey-VCH? 2009, Volume 2? 733-813.

(2)Yuanjing Xiao and Junliang Zhang*，Au- and Pt-Catalyzed C–H Activation/ Functionalizations for the Synthesis of Heterocyclesin Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation(Xiaofeng Wu, Ed), Wiley-VCH, 2016. pp 359-402.

授权专利：
4.2-氟多取代4H-吡喃衍生物及其制备方法，专利授权号：2.6
3.4-多氟烷基-4，5-二取代异噁唑衍生物及其制备方法，专利授权号：7.7
2.一种含多氟烷基五元环状硝酮衍生物及其制备方法，专利授权号：8.6
1.4-多氟烷基-2，4-二取代吡咯衍生物及其制备方法，专利授权号：6.3

主持科研项目：
（1）2013上海市自然科学基金：基于含氟共轭烯炔的有机合成反应设计，10万（项目号：13ZR**）执行年限：2013.7-2016.7；
（2）承担教育部创新团队子课题项目 25万
（3）2017上海市自然科学基金：基于2-三氟甲基-1，3-共轭烯炔的有机合成反应设计，20万（项目号：17ZR**）执行年限：2017.5-2020.4。
（4）2018 国家自然科学基金：新型手性非血红素模拟酶及其分子氧活化的不对称催化作用，64万（项目号：**）执行年限：2019.1-2022.12。

小组成员






已毕业研究生
2012级
曾琴： 获2014年国家奖学金； 毕业去向：上海理工大学
张丽：获2014年校优秀奖学金；毕业去向：深圳市公明中学
2013级
杨洁茹：获2015年国家奖学金；毕业去向：浙江大学附属中学
2014级


周小凡 毕业去向：上海元氏五才医药科技有限公司

曾雨 获2017年分众奖学金；华东师范大学学业奖学金；华东师范大学优秀生源奖学金
毕业去向：重庆市字水中学
黄超乾：获2017年国家奖学金


荣誉及奖励


招生信息














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