个人简介
姓名 闫景坤
性别 男
出生日期 1980年11月
职称 副教授
电话 ——
传真 ——

Email jkyan_27@163.com
详细介绍
【学术简介】
学习经历：
2000年9月-2004年6月，河南工业大学，食品科学与工程专业，学士学位。
2004年9月-2007年6月，河南工业大学，粮食油脂与植物蛋白工程专业，硕士学位。
2007年9月-2010年6月，华南理工大学，制糖工程专业，博士学位。
教学及研究经历：
2010年7月-至今，江苏大学食品与生物工程学院教师。
2012年4月-2015年9月，江苏大学食品科学与工程博士后。
2013年10月-2014年2月，香港理工大学应用生物及化学科技学系，访问****（Research Associate）。
2015年12月-2016年12月，香港中文大学生命科学院，访问****（Research Associate）。
学术社会兼职及荣誉：
中国菌物学会桑黄产业分会理事
【主讲课程】
硕士研究生：
本科生：生物化学、食品工厂设计、食品安全学
【指导硕、博士生研究方向】
硕士研究生：（1）生物大分子多糖的分离纯化、结构表征、活性及其应用；
（2）生物大分子多糖的相互作用、功能化改性及其应用；
（3）食品功能性低聚糖的开发及其应用。

【研究领域】
1．活性多糖的制备、结构、活性及构效关系；
2．生物大分子多糖的相互作用、功能化修饰、活性及应用；
3．农产品新资源（功能低聚糖）的开发及应用。
【主要论著】
近年来，以第一作者或通讯作者在国内外学术刊物Critical Reviews in Food Science & Nutrition、Journal of Agricultural and Food Chemistry、Food & Function、Journal of Functional Foods、Food Chemistry、Carbohydrate Polymers、Ultrasonics Sonochemistry等发表SCI学术论文50篇，影响因子7.0以上2篇，影响因子5.0以上26篇，国际期刊Critical Reviews in Food Science & Nutrition、Journal of Agricultural and Food Chemistry、ACS Applied Materials & Interfaces、Journal of Functional Foods、Carbohydrate Polymers、Food Chemistry、Ultrasonics Sonochemistry、Food & Function等近20多个期刊审稿人，Book chapter1篇，授权发明专利6件。参编中国科学院食品科学与工程专业系列“十二五”规划教材《功能性食品学》和《食品化学》2部。
?代表性论文（著）（“*”为通讯作者）：
2019年
1.Wang, Y.Y., Zhu, J., Ma, H., Ding, Z.C., Li, L., Yan, J.K.* (2019). Antidiabetic activity of a polysaccharide-protein complex from Asian Clam (Corbicula fluminea) in streptozotoxin-induced diabetic rats and underlying mechanism. Food & Function, 10, 5574-5586. (SCI, JCR一区，IF:3.241，TOP期刊)
2.Cai, W.D., Zhu, J., Wu, L.X., Qiao, Z.R., Li, L., Yan, J.K.* (2019). Preparation, characterization, rheological and antioxidant properties of ferulic acid-grafted curdlan conjugates. Food Chemistry, 300, 125221. (SCI, JCR一区，IF: 5.399，TOP期刊)
3.Yan, J.K.*, Wu, L.X., Cai, W.D., Xiao, G.S., Duan, Y., Zhang, H. (2019). Subcritical water extraction-based methods affect the physicochemical and functional properties of soluble dietary fibers from wheat bran. Food Chemistry, 298, 124987. (SCI, JCR一区，IF: 5.399，TOP期刊)
4.Qiu, W.Y., Cai, W.D., Wang, M., Yan, J.K.* (2019). Effect of ultrasonic intesnity on the conformational changes in citrus pectin under ultrasonic processing. Food Chemistry, 297, 125021. (SCI, JCR一区，IF: 5.399，TOP期刊)
5.Wu, L.X., Qiao, Z.R., Cai, W.D., Qiu, W.Y., Yan, J.K.* (2019). Quaternized curdlan/pectin polyelectrolyte complexes as biocompatible nanovehicles for curcumin. Food Chemistry, 291, 180-186. (SCI, JCR一区，IF: 5.399，TOP期刊)
6.Cai, W.D., Qiu W.Y., Ding, Z.C., Wu, L.X., Yan, J.K.* (2019) Conformational and rheological properties of a quaternary ammonium salt of curdlan. Food Chemistry, 280, 130-138. (SCI, JCR一区，IF: 5.399，TOP期刊)
7.Yan, J.K.*, Wu, L.X., Qiao, Z.R., Cai, W.D., Ma, H. (2019). Effect of different drying methods on the product quality and bioactive polysaccharides of bitter gourd (Momordica charantia L.) slice. Food Chemistry, 271, 588-596. (SCI, JCR一区，IF: 5.399，TOP期刊)
8.Wang, Y.Y., Ma, H., Yan, J.K.*, Wang, K.D., Yang, Y., Wang, W.H., Zhang, H.N.* (2019). Three-phase partitioning system with dimethyl carbonate as organic phase for partitioning of exopolysaccharides from Phellinus baumii. International Journal of Biological Macromolecules, 131, 941-948. (SCI, JCR二区，IF 4.784)
9.Wang, Y.Y., Ma, H., Ding, Z.C., Yang, Y., Wang, W.H., Zhang, H.N.*, Yan, J.K.* (2019). Three-phase partitioning for the direct extraction and separation of bioactive exopolysaccharides from the cultured broth of Phellinus baumii. International Journal of Biological Macromolecules, 123, 201-209. (SCI, JCR二区，IF 4.784)
10.Wu, Y., Liu, H., Li, Z., Huang, D., Nong, L., Ning, Z., Hu, Z., Xu, C., Yan, J.K*. (2019). Pectin-decorated selenium nanoparticles as a nanocarrier of curcumin to achieve enhanced physicochemical and biological properties. IET Nanobiotechnology, DOI: 10.1049/iet-nbt.2019.0144 (SCI, JCR三区，IF: 1.925).
2018年
1.Yan, J.K*., Wang, Y.Y., Qiu, W.Y., Ma, H., Wang, Z.B., & Wu, J.Y. (2018). Three-phase partitioning as an elegant and versatile platform applied to non-chromatographic bioseparation process. Critical Reviews in Food Science and Nutrition, 58(14), 2416-2431. (SCI, JCR一区, IF 6.704，Top期刊).
2.Wang, Y.Y., Qiu Wen-Yi, Sun L., Ding, Z.C., Yan, J.K.* (2018). Preparation, characterization, and antioxidant capacities of selenium nanoparticles stabilized using polysaccharide-protein complexes from Corbicula fluminea. Food Bioscience, 26， 177-184 (SCI, JCR三区，IF:3.220)
3.Hu, T., Lin, Q., Guo, T., Yang, T., Zhou, W., Deng, X., Yan, J.K.*, Luo, Y., Ju, M., Luo, F. (2018). Polysaccharide isolated from Phellinus linteus mycelia exerts anti-inflammatory effects via MAPK and PPAR signaling pathways. Carbohydrate Polymers, 200, 487-497. (SCI, JCR一区，IF: 6.044，TOP期刊)
4.Qiu, W.Y., Wang, Y.Y., Wang, M., Yan, J.K*. (2018). Construction, stability, and enhanced antioxidant activity of pectin-decorated selenium nanoparticles. Colloids and Surfaces B: Biointerfaces, 170, 692-700. (SCI, JCR二区，IF:3.973).
5.Yan, J.K.*, Ding, Z.C., Gao, X., Wang, Y.Y., Yang, Y., Wu, D., Zhang, H.N.* (2018). Comparative study of physicochemical properties and bioacitvity of Hericium erinaceus polysaccharides at different solvent extractions. Carbohydrate Polymers, 193,373-382. (SCI, JCR一区，IF: 6.044，TOP期刊)
6.Yan, J.K*, Qiu, W.Y., Wang, Y.Y., Wang, W.H., Yang, Y., Zhang, H.N.* (2018). Fabrication and stabilization of biocompatible selenium nanoparticles by carboxylic curdlans with various molecular properties. Carbohydrate Polymers, 179,19-27. (SCI, JCR一区，IF: 6.044，TOP期刊)
7.Yan, J.K*., Wang, Y.Y., Qiu, W.Y., Ma, H., Wang, Z.B. (2018). Ultrasound synergized with three-phase partitioning for extraction and separation of Corbicula fluminea polysaccharides and possible relevant mechanisms. Ultrasonics Sonochemistry, 40, 128-134. (SCI, JCR一区，IF:7.279，TOP期刊).
8.Qiu, W.Y., Wang, K., Wang, Y.Y., Ding, Z.C., Wu, L.X., Cai, W.D., Yan, J.K*. (2018). pH dependent green synthesis of gold nanoparticles by completely C6-carboxylated curdlan under high temperature and various pH conditions. International Journal of Biological Macromolecules, 106, 498-506. (SCI, JCR二区，IF 4.784)
9.Yan, J.K*, Qiu, W.Y., Wang, Y.Y., Wu, L.X., Cheung, P.C.K*. (2018). Formation and characterization of polyelectrolyte complex synthesized by chitosan and carboxylic curdlan for 5-fluorouracil delivery. International Journal of Biological Macromolecules, 107, 397-405. (SCI, JCR二区，IF 4.784)
10.Zhang, H.N., Ma, Hai-Le, Zhou, C.S., Yang, Y., Yin, X.L., & Yan, J.K*. (2018). Enhanced production and antioxidant activity of endo-polysaccharides from Phellinus igniarius mutants screened by low power He-Ne laser and ultraviolet induction. Bioactive Carbohydrates and Dietary Fibre, 15, 30-36.
2017年
1.Yan, J.K*, Wang, Y.Y., Qiu, W.Y., Wu, L.X., Ding, Z.C., Cai, W.D. (2017). Purification, structural characterization and bioactivity evaluation of a novel proteoglycan produced by Corbicula fluminea. Carbohydrate Polymers, 176, 11-18. (SCI, JCR一区，IF: 6.044，TOP期刊)
2.Yan, J.K*., Qiu, W.Y., Wang, Y.Y., & Wu, J.Y. (2017). Biocompatible polyelectrolyte complex nanoparticles from lactoferrin and pectin as potential vehicles for antioxidative curcumin. Journal of Agricultural and Food Chemistry, 65(28), 5720-5730. (SCI, JCR一区，IF 3.571, TOP期刊).
3.Yan, J.K*., Wang, Y.Y., Qiu, W.Y., & Wu, J.Y. (2017). Construction and characterization of nanosized curdlan sulfate/chitosan polyelectrolyte complex toward drug release of zidovudine. Carbohydrate Polymers, 174, 209-216. (SCI, JCR一区，IF: 6.044，TOP期刊)
4.Yan, J.K*., Pei, J.J., Ma, H.L., Wang, Z.B., & Liu, Y.S. (2017) Advances in Antitumor Polysaccharides from Phellinus sensu lato: Production, Isolation, Structure, Antitumor Activity, and Mechanisms. Critical Reviews in Food Science and Nutrition. 57(6): 1256-1269. (SCI, JCR一区, IF 6.704，Top期刊).
5.Yan, J.K*., Wang, Y.Y., Qiu, W.Y., Shao, N. (2017). Three-phase partitioning for efficient extraction and separation of polysaccharides from Corbicula fluminea. Carbohydrate Polymers, 163, 10-19. (SCI, JCR一区，IF: 6.044，TOP期刊)
6.Yan, J.K*., Wu, L.X., Qiu, W.Y., Wang, Y.Y., Ding, Z.C., Cai, W.D. (2017). Rheological properties of a ?-1,3-polyglucuronic acid derivative from 4-acetamido-TEMPO-mediated oxidation of curdlan. RSC Advances, 7, 50441-50448. (SCI, JCR三区IF: 3.049).
7.Wang, Y.Y., Qiu, W.Y., Wang, Z.B., Ma, H.L., Yan, J.K*. (2017). Extraction and characterization of anti-oxidative polysaccharide–protein complexes from Corbicula fluminea through three-phase partitioning. RSC Advances, 7, 11067-11075. (SCI, JCR三区IF: 3.049).
2016年
1.Yan, J.K*., Wang, Y.Y., Zhu, L., & Wu, J.Y*. (2016) Green synthesis and characterization of zinc oxide nanoparticles using carboxylic curdlan and their interaction with bovine serum albumin. RSC Advances, 6, 77752-77759 (SCI, JCR三区IF: 3.049).
2.Wang, Z.B., Chen, B.B., Luo, L., & Yan, J.K*. (2016) Fractionation, physicochemical characteristics and biological activities of polysaccharides from Pueraria lobata roots. Journal of the Taiwan Institute of Chemical Engineers, 67， 54-60. (SCI, JCR二区，IF: 3.834)
3.Yan, J.K*., Wang, Y.Y., Wang, Z.B., Ma, H.L., Pei, J.J. (2016). Structural characteristics and antioxidant activity in vivo of a polysaccharide isolated from Phellinus linteus mycelia. Journal of the Taiwan Institute of Chemical Engineers, 65, 110-117. (SCI, JCR二区，IF: 3.834)
4.Yan, J.K*., Wang, Y.Y., Wang, Z.B., Ma, H.L., Pei, J.J., & Wu, J.Y*. (2016). Structure and antioxidative property of a polysaccharide from an ammonium oxalate extract of Phellinus linteus. International Journal of Biological Macromolecules, 9, 92-99. (SCI, JCR二区，IF :4.784)
5.Yan, J.K*., Wang, Y.Y., Wang, Z.B., Ma, H.L. (2016). Ultrasonic effects on the degradation kinetics, preliminary characterization and antioxidant activities of polysaccharides from Phellinus linteus mycelia. Ultrasonics Sonochemistry, 29, 251-257. (SCI, JCR一区，IF:7.279，TOP期刊).
2015年
1.Yan, J.K*., Pei, J.J., Ma, H.L., Wang, Z.B. (2015). Effects of ultrasound on molecular properties, structure, chain conformation and degradation kinetics of carboxylic curdlan. Carbohydrate Polymers. 121,64-70. (SCI, JCR一区，IF: 6.044，TOP期刊)
2.Yan, J.K*., Liu J.L., Sun, Y.J., Tang, S., Mo, Z.Y., & Liu, Y.S.* (2015). Green synthesis of biocompatible carboxylic curdlan-capped gold nanoparticles and its interaction with protein. Carbohydrate Polymers.117,771-777. (SCI, JCR一区，IF: 6.044，TOP期刊)
3.Yan, J.K*., Ma, H.L., Chen, X., Pei, J.J., Wang, Z.B., Wu, J.Y.* (2015). Self-aggregated nanoparticles of carboxylic curdlan-deoxycholic acid conjugates as a carrier of doxorubicin. International Journal of Biological Macromolecules, 72, 333-340. (SCI, JCR二区，IF 4.784)
4.Yan, J.K*., Ma, H.L., Cai, P.F., Wu, J.Y.* (2015). Highly selective and sensitive nucleic acid detection based on polysaccharide-functionalized silver nanoparticles. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 134, 17-21. (SCI, JCR二区，IF:2.931).
5.Pei, J.J., Wang, Z.B., Ma, H.L., Yan, J.K*. (2015). Structural features and antitumor activity of a novel polysaccharide from alkaline extract of Phellinus linteus mycelia. Carbohydrate Polymers, 115, 472-477 (SCI, JCR一区，IF: 6.044，TOP期刊)
6.Yan, J.K*., Wang, Y.Y., Ma, H.L. (2015). Green synthesis and stabilization of gold nanoparticles via carboxymethylated curdlan. Current Topics in Nutraceutical Research, 13(4):259-266 (SCI，JCR四区).
7.Yan, J.K.*, Wang, Y.Y. (2015). Random-centroid optimization of ultrasound- -assisted extraction of polysaccharides from Cordyceps sinensis mycelium. Current Topics in Nutraceutical Research, 13(4):167-172 (SCI，JCR四区).
2014年
1.Zhang, H.N., Ma, H.L.,* Liu, W., Pei, J.J., Wang, Z.B., Zhou, H.J., Yan, J.K*. (2014). Ultrasound enhanced production and antioxidant activity of polysaccharides from mycelial fermentation of Phellinus igniarius. Carbohydrate Polymers, 113, 380-387. (SCI, JCR一区，IF: 6.044，TOP期刊)
2.Yan, J.K*., Ma, H.L., Pei, J.J., Wang, Z.B., Wu, J.Y.* (2014). Facile and effective separation of polysacchrides and proteins from Cordyceps sinensis mycelia by ionic liquid aqueous two-phase system. Separation and Purification Technology,135, 278-284. (SCI, JCR二区，IF:5.107).
3.Wang, Z.B., Pei, J.J., Ma, H.L., Cai, P.F., Yan, J.K.* (2014). Effect of extraction media on preliminary characterizations and antioxidant activities of Phellinus linteus polysaccharides. Carbohydrate Polymers, 109: 49-55. (SCI, JCR一区，IF: 6.044，TOP期刊)
4.Yan, J. K.,* Wang, W.Q., & Wu, J.Y.* (2014). Recent advances in Cordyceps sinensis polysaccharides: mycelial fermentation, isolation, structure, and bioactivities: a review. Journal of Functional Foods, 6, 33-47. (SCI, JCR一区IF:3.197, TOP期刊)
5.Yan, J.K.*, Ma, H.L., Cai, P.F., Zhang, Q., Hu, N.Z., Feng, X.B., Wu, J.Y.* (2014) Structural characteristics and antioxidant activities of different families of 4-acetamido-TEMPO-oxidized curdlan. Food Chemistry, 143, 530-535. (SCI, JCR一区，IF: 5.399，TOP期刊)
2013年及以前
1.Yan, J.K.*, Cai P.F., Cao, X.Q., Ma, H.L., Zhang, Q., Hu, N.Z., Zhao, Y.Z. (2013). Green synthesis of silver nanoparticles using 4-acetamido-TEMPO-oxidized curdlan. Carbohtdrate Polymers, 97, 391-397. (SCI, JCR一区，IF: 6.044，TOP期刊)
2.Yan, J.K.*, Cai, P.F., Cao, X.Q., Fan, T.T., Ma, H.L. (2013). Studies on interaction of polysaccharide-templated silver nanoparticles with bovine serum albumin. Journal of Inorganic and Organometallic Polymers and Materials, 23, 1383-1388. (SCI, JCR四区，IF:1.637)
3.Yan, J. K., Wang, W.Q., Ma, H.L., & Wu, J.Y.* (2013). Sulfation and enhanced antioxidant capacity of an exopolysaccharide produced by the medicinal fungus Cordyceps sinensis. Molecules, 18(1), 167-177. (SCI, JCR三区，IF:3.060)
4.Yan, J. K., Wang, W.Q., Li, L., & Wu, J.Y.* (2011). Physiochemical properties and antitumor activities of two α-glucans isolated from hot water and alkaline extracts of Cordyceps (Cs-HK1) fungal mycelia, Carbohydrate Polymers, 85, 753-758. (SCI, JCR一区，IF: 6.044，TOP期刊)
5.Yan, J. K., Li, L., Wang, Z. M., & Wu, J.Y.* (2010).Structural elucidation of an exopolysaccharide from mycelial fermentation of a Tolypocladium sp. fungus isolated from wild Cordyceps sinensis, Carbohydrate Polymers, 79(1), 125-130. (SCI, JCR一区，IF: 6.044，TOP期刊)
6.Yan, J. K., Li, L., Wang, Z. M.,Leung, P. H., Wang,W. Q., & Wu, J.Y.* (2009). Acidic degradation and enhanced antioxidant activities of exopolysaccharides from Cordyceps sinensis mycelial culture, Food Chemistry, 117(4), 641-646. (SCI, JCR一区，IF: 5.399，TOP期刊)

【科研项目】
在研项目：
1.国家自然科学基金-面上项目：超声场微环境中果胶溶液构象的转变规律、机理及与功能性质的构效关系（**）， 2017.01-2020.12，主持，在研。
2.江苏省现代农业重点研发面上项目：麦麸可溶性膳食纤维绿色高效制备关键技术研究与应用（BE**），2017.7-2019.6，技术主持，在研。
结题项目：
1.江苏省自然科学基金-青年基金项目：桑黄活性多糖抗肿瘤作用的肠道黏膜免疫机制研究（BK**），2014.7-2017.6，主持，已结题。
2.中国博士后科学基金面上项目：可德兰硫酸酯溶液构象与抗HIV-1活性的构效关系（2013M531292），2013.7-2015.6，主持，已结题。
3.南昌大学食品科学与技术国家重点实验室开放基金：桑黄多糖调节肠粘膜γδT细胞免疫的抗肿瘤作用及机理研究（SKLF-KF-201611），2016.5 -2018.12，主持，已结题。
4.江苏大学高级人才基金资助项目：新型药用虫草胞外多糖结构表征、修饰及抗氧化构效关系（105DG129），2010.10-2013.10，主持，已结题。
5.江南大学糖化学与生物技术教育部重点实验室开放基金项目：微波辅助多糖基银纳米粒子合成及其抗HIV-1活性的构效关系（KLCCB-KF201203），2012.12-2014.12，主持，已结题。
6.江苏省农产品物理加工重点实验室开放基金项目：逆流循环超声辅助桑黄多糖的制备与抗肿瘤血管生成构效关系的研究（JAPP2010-7），2012.5-2014.5，主持，已结题。
7.农业部公益性行业科研专项-子课题：长江流域等三区域稻谷储藏技术设施研究与示范（），2010.12-2014.12，第二负责人，已结题。
8.国家自然科学基金-面上项目：蛋白质扫频超声预处理促进其酶解反应的机理及控制机制研究（**），2011.1-2013.12，排名第四，已结题。
9.江苏省科技支撑计划（农业部分）项目：麦胚降血压肽制备关键技术的放大及麦胚多肽香醋的开发研究（BE**），2011.7-2013.7，排名第三，已结题。
【科研成果及奖励】
教学获奖：
2012年江苏大学第六届教师教学竞赛新教师组优秀奖
2016-2018年度江苏大学优秀教师
【所获专利】
目前申请发明专利10余项，授权7项：
1. 发明专利：一种多糖基银纳米粒子的制备方法. ZL 8.2
2. 发明专利：一种虫草菌丝体多糖分离纯化的方法. ZL 3.4
3. 发明专利：一种脱氧胆酸基-氧化可德兰多糖纳米粒子及制备方法. ZL 3.X
4. 发明专利：一种香菇多糖快速分离的方法. ZL 0.0
5. 发明专利：一种多糖衍生物诱导的金纳米粒子的可控制备方法. ZL 8.8
6. 发明专利：一种利用胆碱离子液双水相体系分离多糖和蛋白质的方法. ZL 3.2
7. 发明专利：一种用于糙米脂肪酶酶活稳定和食用品质改善的处理方法. 授权号：20**532
【在读硕、博士人数】
硕士研究生6人

【已毕业硕、博士人数】
硕士研究生3人

【指导本科生人数】
21人

【以上资料更新日期】
2019年10月17日