邵珠卿 副教授 硕士生导师





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联系地址：
电子邮件： zhuqingshao@126.com








个人简介
研究方向
科研成果





个人简介

学习经历
2010.9—2013.5， 南京大学生命科学院 生物学专业，博士
2007.9—2010.6， 南京师范大学生命科学院 细胞生物学专业，硕士
2003.9—2007.6， 烟台大学化学生物理工学院 生物技术专业，学士

工作经历
2016.9-至今，南京大学生命科学学院，副教授
2013.5—2016.8， 南京大学生命科学学院，博士后


学术兼职
Guest Associate Editor, Frontiers in Genetics
Guest Associate Editor,Frontiers in Ecology and Evolution


研究方向

1.植物与微生物互作及共演化研究
1）植物最大抗病基因家族NBS-LRR基因的起源及演化机制研究；
2）GRAS基因家族调控植物与微生物共生的网络模式及演化机制；
?2.植物进化-发育生物学研究
?1）植物基因组演化；
2）植物重要基因家族的演化和功能研究；



获奖情况


2019年 江苏医学科技奖三等奖（排名第二）
2012年 生命科学前沿与农业生物技术创新全国博士生学术论坛，最佳报告奖

2013年南京市第十届自然科学优秀学术论文（优秀奖）
2011年南京市第九届自然科学优秀学术论文（二等奖）
2009年 江苏省微生物学会年会，优秀报告论文



科研成果
主持项目：
1.国家自然科学基金青年基金：植物RPW8-NBS-LRR类抗病信号传导基因的起源、演化及功能化机制，2015-2017，25万，项目主持人。
2.中国博士后科学基金特别资助：植物microRNA对NBS-LRR抗病基因调控作用的起源及演化，2014-2015，15万，项目主持人。
3.中国博士后科学基金面上项目一等资助：植物NBS-LRR类抗病基因的起源及早期演化分析，2013-2015，8万，项目主持人。
4.中央高校基本科研业务费苗圃项目：8万，项目主持人。
5.中央高校基本科研业务费：10万，项目主持人。
6.中央高校基本科研业务费：30万，项目主持人。
7.江苏省博士后科研资助计划C类资助：大豆Rpg1-b复合抗病位点的起源、演化及功能化机制，2013-2015，1万，项目主持人。
8.江苏省研究生科研创新计划（资助）：基因中同义密码子有序性排列的规律及生物学意义研究，2011-2012，1.5万。项目主持人。

发表论文：
1. 第一作者和共同第一作者论文
（1）Zhu-Qing Shao^#, Jia-Yu Xue^#, Qiang Wang, Bin Wang, Jian-Qun Chen*. Revisiting the origin of plant NBS-LRR genes. Trends in Plant Science, 2019, 24(1): 10-13
（2） Zhu-Qing Shao#, Jia-Yu Xue#, Ping Wu, Yan-Mei Zhang, Yue Wu, Yue-Yu Hang, Bin Wang*, Jian-Qun Chen*, Large-scale analyses of angiosperm nucleotide-binding site-leucine-rich repeat (NBS-LRR) genes reveal three anciently diverged classes with distinct evolutionary patterns, Plant Physiol, 2016, 170(4): 2095-109
（3）Zhu-Qing Shao#, Yan-Mei Zhang#, Yue-Yu Hang, Jia-Yu Xue, Guang-Can Zhou, Ping Wu, Xiao-Yi Wu, Xun-Zong Wu, Qiang Wang, Bin Wang*, Jian-Qun Chen*, Long-Term Evolution of Nucleotide-Binding Site-Leucine-Rich Repeat (NBS-LRR) Genes: Understandings Gained From and Beyond the Legume Family,Plant Physiol, 2014, 166(1): 217–234
（4）Zhu-Qing Shao, Wang B*, Chen JQ*, Tracking ancestral lineages and recent expansions of NBS-LRR genes in angiosperms,Plant Signal Behav, 2016, 11 (7):e**
（5）Zhu-Qing Shao#, Yan-Mei Zhang#, Bin Wang*, Jian-Qun Chen*, Computational Identification of MicroRNA-targeted Nucleotide-Binding Site-Leucine-Rich Repeat Genes in Plants,Bio-protocol, 2015, 5 (21), e1637
（6）Zhu-Qing Shao#, Yan-Mei Zhang#, Xiu-Zhen Pan, Bin Wang*, Jian-Qun Chen*, Insight into the Evolution of the Histidine Triad Protein (HTP) Family in Streptococcus, PLOS ONE, 2013, 8 (3), e60116
（7）Zhu-Qing Shao, Yan-Mei Zhang, Xue-Ying Feng, Bin Wang*, Jian-Qun Chen*, Synonymous Codon Ordering: A Subtle but Prevalent Strategy of Bacteria to Improve Translational Efficiency, PLoS ONE, 2012, 7(3): e33547
（8）Zhuqing Shao#, Xiuzhen Pan#, Xianfu Li, Wenjing Liu, Mingyue Han, Changjun Wang, Jing Wang, Feng Zheng, Min Cao, Jiaqi Tang*, HtpS, anovel immunogenic cell surface exposed protein of Streptococcus suis, confers protection in mice, FEMS Microbiol Lett, 2011, 314(2):172-184
（9） Yan-Mei Zhang#, Zhu-Qing Shao#, Qiang Wang, Yue-Yu Hang, Jia-Yu Xue, Bin Wang*, Jian-Qun Chen*, Uncovering the dynamic evolution of nucleotide-binding site-leucine-rich repeat (NBS-LRR) genes in Brassicaceae, J Integr Plant Biol, 2016, 58(2):165-77
（10）Feng Zheng^#, Zhu-Qing Shao^#, Xina Hao, Qianqian Wu, Chaolong Li, Hongfen Hou, Dan Hu, Changjun Wang, Xiuzhen Pan*. Identification of oligopeptide-binding protein (OppA) and its role in the virulence of Streptococcus suis serotype 2. Microbial Pathogenesis. 2018, 118, 322-329
（11） Min Li#, Zhu-Qing Shao#, Yuqing Guo#, Ling Wang#, Tianqing Hou, Dan Hu, Feng Zheng, Jiaqi Tang, Changjun Wang, Youjun Feng, Jimin Gao*, Xiuzhen Pan*, The type II histidine triad protein HtpsC is a novel adhesion with the involvement of Streptococcus suis virulence, Virulence, 2015, 6(6): 631–641
（12）Guang-Can Zhou#, Zhu-Qing Shao#, Fang-Fang Ma, Ping Wu, Xiao-Yi Wu, Zhong-Yun Xie, De-Yue Yu, Hao Cheng, Zhi-Hua Liu, Zhen-Feng Jiang, Qing-Shan Chen, Bin Wang*, Jian-Qun Chen*, The evolution of soybean mosaic virus: An updated analysis by obtaining 18 new genomic sequences of Chinese strains/isolates, Virus Res, 2015, 208:189-98
（13） Ping Wu#, Zhu-Qing Shao#, Xun-Zong Wu, Qiang Wang, Bin Wang, Jian-Qun Chen, Yue-Yu Hang, Jia-Yu Xue*, Loss/retention and evolution of NBS-encoding genes upon whole genome triplication of Brassica rapa, Gene, 2014, 540(1):54-61
（14） Yan-Mei Zhang#, Zhu-Qing Shao#, Jing Wang, Ling Wang, Xianfu Li, Changjun Wang, Jiaqi Tang, Xiuzhen Pan*, Prevalent distribution and conservation of streptococcus suis Lmb protein and its protective capacity against the Chinese highly virulent strain infection, Microbiol Res, 2014, 169(5–6): 395–401
（15） Yan-Mei Zhang#, Zhu-Qing Shao#, Le-Tian Yang, Xiao-Qin Sun, Ya-Fei Mao, Jian-Qun Chen*, Bin Wang*, Non-random arrangement of synonymous codons in Archaea coding sequences, Genomics, 2013, 101(6):362-7
（16）Bin Wang#, Zhu-Qing Shao#, Ying Xu, Jing Liu, Yuan Liu, Yue-Yu Hang*, Jian-Qun Chen*, Optimal codon identities in bacteria: implications from the conflicting results of two different methods, PLoS ONE, 2011, 6(7): e22714
（17）Guanting Niu^#, Zhuqing Shao^#, Chuanfa Liu, Tianshu Chen, Qingsong Jiao, Zhi Hong. Comparative and evolutionary analyses of the divergence of plant oligosaccharyltransferase STT3 isoforms. FEBS Open Bio. 2020, 10(3):468-483.

2. 通讯作者论文
（1）Jia-Yu Xue , Frank L.W. Takken , Madhav P. Nepal , Takaki Maekawa and Zhu-Qing Shao*. Editorial: Evolution and Functional Mechanisms of Plant Disease Resistance. Front Genet. 2020, doi: 10.3389/fgene.2020.593240.
（2）Jia-Yu Xue, Yue Wang, Min Chen, Shanshan Dong, Zhu-Qing Shao*, Yang Liu*. Maternal Inheritance of U's Triangle and Evolutionary Process of Brassica Mitochondrial Genomes. Front Plant Sci. 2020, 11:805.
（3）Hua Ni^#, Min Li^#, Qiaoqiao Wang^#, Jing Wang, Xumiao Liu, Feng Zheng, Dan Hu, Xu Yu, Yifang Han, Qi Zhang, Tingting Zhou, Yiwen Wang, Chunhui Wang*, Jimin Gao*, Zhu-Qing Shao*, Xiuzhen Pan*. Inactivation of the htps A gene affects capsule development and pathogenicity of Streptococcus suis. Virulence. 2020, 11(1):927-940.
（4）Jia-Yu Xue, Tao Zhao, Yang Liu, Yang Liu, Yong-Xia Zhang, Guo-Qiang Zhang, Hongfeng Chen, Guang-Can Zhou*, Shou-Zhou Zhang*, Zhu-Qing Shao*. Genome- Wide Analysis of the Nucleotide Binding Site Leucine-Rich Repeat Genes of Four Orchids Revealed Extremely Low Numbers of Disease Resistance Genes. Front Genet, 2020, 10:1286.
（5）Yue Wu^#, Ping Wu^#, Bin Wang, Zhu-Qing Shao*.Genome-wide Analysis Reveals Ancestral Lack of Seventeen Different tRNAs and Clade-specific Loss of tRNA-CNNs in Archaea.Front Microbiol,2018, 9: 1245
（6）Hua Ni^#, Weiwei Fan^#, Chaolong Li, Qianqian Wu, Hongfeng Hou, Dan Hu, Feng Zheng, Xuhui Zhu, Changjun Wang, Xiangrong Cao*,Zhu-Qing Shao*, Xiuzhen Pan*. Streptococcus suis DivIVA protein is a substrate of Ser/Thr kinase STK and involved in cell division regulation.Front Cell Infect Microbiol,2018, 8: 85.
（7）Yan-Mei Zhang, Jia-Yu Xue, Li-Wei Liu, Xiao-Qin Sun, Guang-Can Zhou, Min Chen,Zhu-Qing Shao*, Yue-Yu Hang*. Divergence and conservative evolution of XTNX genes in land plants.Front Plant Sci,2017, 8:1844.
（8）Ping Wu, Yue Wu, Cheng-Chen Liu, Li-Wei Liu, Fang-Fang Ma, Xiao-Yi Wu, Mian Wu, Yue-Yu Hang, Jian-Qun Chen, Zhu-Qing Shao*, Bin Wang*. Identification of arbuscular mycorrhiza (AM)-responsive microRNAs in tomato. Front Plant Sci. 2016, 7: 429.
（9）Guang-Can Zhou^#, Xiao-Yi Wu^#, Yan-Mei Zhang, Ping Wu, Xun-Zong Wu, Li-Wei Liu, Qiang Wang, Yue-Yu Hang, Jia-Yin Yang, Zhu-Qing Shao*, Bin Wang*, Jian-Qun Chen*.A genomic survey of thirty soybean-infecting bean common mosaic virus (BCMV) isolates from China pointed BCMV as a potential threat to soybean production. Virus Res. 2014, 191C: 125-133.

3. 其它论文
（1）Fang-Fang Ma, Xiao-Yi Wu, Yun-Xia Chen, Ying-Na Liu, Zhu-Qing Shao, Ping Wu, Mian Wu, Cheng-Chen Liu, Wen-Ping Wu, Jia-Yin Yang, De-Xiao Li, Jian-Qun Chen,Bin Wang, Fine mapping of the Rsv1-h gene in the soybean cultivar Suweon 97 that confers resistance to two Chinese strains of the soybean mosaic virus, Theor Appl Genet, 2016, 129: 2227
（2）Youjun Feng#, Xiuzhen Pan#, Wen Sun#, Changjun Wang, Huimin Zhang H, Xianfu Li, Ying Ma, Zhuqing Shao, Junchao Ge, Feng Zheng, Fu Gao*, Jiaqi Tang*, Streptococcus suis enolase functions as a protective antigen displayed on the bacterial cell surface, J Infect Dis, 2009, 200(10): 1583-92.

专利：
1. 潘秀珍，李敏，王晶，王长军，邵珠卿，李先富，高基民。猪链球菌2型htpsA基因敲除突变株及其应用。 专利号：1，公开(公告)号：CNA。专利申请日：2013.07.02，公开(公告)日：2013.10.16。
2. 潘秀珍，李敏，王晶，王长军，邵珠卿，李先富，高基民。猪链球菌2型htpsC基因敲除突变株及其应用。 专利号：8，公开(公告)号：CNA。专利申请日：2013.07.02，公开(公告)日：2013.10.09。