刘红林 详细介绍
性别 男
职称 教授
最高学历 博士
毕业院校 南京师范大学
专业领域 动物遗传育种与繁殖
联系方式 liuhonglin@njau.edu.cn；**
研究方向 动物分子育种；动物繁殖性状的调控
参加学术团体
及任职情况 中国畜牧兽医学会理事；中国畜牧兽医学会畜禽遗传标记学会副理事长；中国畜牧兽医学会动物遗传育种学会常务理事；江苏省畜牧兽医学会副理事长；江苏省动物学会副理事长
承担项目 1、“卵泡闭锁的分子机制”（2007CB947403），2007-2010，“973”课题，主持，经费550万元。2、“节粮型高瘦肉率转基因猪新品种培育”（2008ZX08006-003），2008-2017，转基因生物新品种培育重大专项任务，主持，经费900万元。3、“猪肉质性状的表观遗传学调控”（2007AA10Z100），2007-2010，“863”项目，主持，经费70万元。4、“小鼠卵细胞质对供体核DNA甲基化和印记基因表达的调控”（），2005-2007，国家自然科学基金，主持，经费19万元。5、“组蛋白去乙酰化对小鼠核移植胚基因组重序的调控”（**），2006-2008，国家自然科学基金，主持，经费19万元。6、“DOT1调节卵母细胞减数分裂的机制及其对胚胎早期发育的影响”（**），2008-2010，国家自然科学基金，主持，经费30万元。7、“JMJD2 蛋白家族对小鼠早期胚胎H3K9 甲基化修饰及发育能力的影响”（**），2011-2013，国家自然科学基金，主持，经费38万元。8、let-7家族miRNA调控猪卵泡闭锁的分子机制(**)，2012-2015，国家自然科学基金，主持，经费58万元。9、杂交细胞中小鼠ES细胞诱导体细胞核基因组重序的分子机制（NCET-05-0493），2006-2009，教育部新世纪优秀人才支持计划，主持，经费35万元。10、家禽生物反应器研究（2007AA100504），2007-2010，863重点项目，子课题主持，经费40万元。11、猪发情障碍的内分泌与表观遗传机理（2014CB138502），2014-2018，“973”课题，主持，480万元。12、猪肝脏IGF1基因表达调控机制研究（**），2015-2018，国家自然科学基金，主持，88万元。13、氧化应激对猪有腔卵泡闭锁的影响及机制（**），2017-2020，国家自然科学基金重点项目，主持，260万元。
奖励及荣誉 教育部“新世纪优秀人才支持计划”；江苏省“六大高峰人才”高层次人才；近年来获上海市科技进步二等奖、中华农业科技奖二等奖各一次；获国家优秀教学成果二等奖、江苏省优秀教学成果奖一、二等奖各一次。
论文论著
近三年发表论文：
1. Zhou J,Yao W,Li C,Wu W,Li Q,Liu H*. Administration offollicle-stimulating hormone induces autophagy via upregulation of HIF-1α in mouse granulosa cells. CellDeath Dis.2017 Aug 17;8(8):e3001
2. Tao C,Li J,Zhang X,Chen B,Chi D,Zeng Y,Niu Y,Wang C,Cheng W,Wu W,Pan Z,Lian J,Liu H*,Miao YL*.Dynamic Reorganization ofNucleosome Positioning in Somatic Cells after Transfer into Porcine EnucleatedOocytes. StemCell Reports.2017,9(2):642-653
3. Shen M,Jiang Y,Guan Z,Cao Y,Li L,Liu H*,Sun SC*. Protective mechanism of FSH against oxidative damage in mouse ovariangranulosa cells by repressing autophagy. Autophagy.2017 , 13(8):1364-1385
4. Tang Y,Pan B,Zhou X,Xiong K,Gao Q,Huang L,Xia Y,Shen M,Yang S,Liu H,Tan T,Ma J,Xu X,Mu Y,Li K. Wip1-dependent modulation of macrophage migration and phagocytosis. Redox Biol.2017 ;13:665-673
5. Tao C,Li J,Chen B,Chi D,Zeng Y,Liu H*. Genome-scale identification of nucleosomeorganization by using 1000 porcine oocytes at different developmental stages. PLoS One.2017, 12(3):e**
6. Zhang M,Dai X,Lu Y,Miao Y,Zhou C,Cui Z,Liu H,Xiong B. Melatonin protects oocyte quality from Bisphenol A-induced deteriorationin the mouse. J Pineal Res.2017, 62(3)
7. Tang X,Xu S,Zhang H,Chen Q,Li R,Wu W,Yu M,Liu H*. Retinoic acid promotes expression of germline-specific genes in chickenblastoderm cells by stimulating Smad1/5 phosphorylation in a feeder-freeculture system. BMC Biotechnol.2017, 20, 17(1):17
8. Weng Q,Liu Z,Li B,Liu K,Wu W,Liu H*. Oxidative Stress Induces Mouse Follicular Granulosa Cells Apoptosis viaJNK/FoxO1 Pathway. PLoS One.2016 ,11(12):e**
9. Shen M,Jiang Y,Guan Z,Cao Y,Sun SC,Liu H*. FSH protects mouse granulosa cells from oxidative damage by repressingmitophagy. Sci Rep.2016, 6:38090
10. Du X,Zhang L,Li X,Pan Z,Liu H,Li Q. TGF-β signaling controls FSHR signaling-reduced ovarian granulosa cellapoptosis through the SMAD4/miR-143 axis. Cell Death Dis.2016, 7(11):e2476
11. Li B,Dong C,Li P,Ren Z,Wang H,Yu F,Ning C,Liu K,Wei W,Huang R,Chen J,Wu W*,Liu H*. Identification of candidate genesassociated with porcine meat color traits by genome-wide transcriptome analysis. Sci Rep.2016, 6:35224
12. Tang X,Xu S,Li R,Zhang H,Chen Q,Wu W,Liu H*. Polycomb repressive complex 1 (PRC1) regulates meiotic initiation ofovarian germ cells in chick embryos. Mol Cell Endocrinol.2016, 437:171-182
13. Zhou J,Yao W,Liu K,Wen Q,Wu W,Liu H,Li Q. MicroRNA let-7g regulates mouse granulosa cell autophagy by targetinginsulin-like growth factor 1 receptor. Int J BiochemCell Biol.2016, 78:130-140
14. Fulu Dong, Zhenwei Song, JialiYu, Baole Zhang, Baochun Jiang, Ying Shen, Youde Lu, Chunle Song, Honglin Liu*.Dynamic Changes in Occupancy of Histone Variant H2A.Z during Induced SomaticCell Reprogramming. Stem Cell International, 2016, Article ID **,10 pages.
15. M. A. Alsiddig, S. G. Yu, Z. X.Pan, H. Widaa, T. M. Badri, J. Chen and H. L. Liu*. Association of single nucleotidepolymorphism in melatonin receptor 1A gene with egg production traits inYangzhou geese. Animal Genetics, 2016, 48: 245–249
16. Wei Han, Jianmin Zou, KehuaWang, Yijun Su, Yunfen Zhu, Chi Song, Guohui Li, Liang Qu, Huiyong Zhang, HonglinLiu*. High-Throughput Sequencing Reveals Hypothalamic MicroRNAs as NovelPartners Involved in Timing the Rapid Development of Chicked Gonads. PLOSONE, 2015, 10(6):e**
17. M. A. Alsiddig, S. G. Yu, Z. X.Pan, H. Widaa, T. M. Badri, J. Chen and H. L. Liu*. Association ofsingle nucleotide polymorphism in melatonin receptor 1A gene with eggproduction traits in Yangzhou geese. Animal Genetics, 2016, 48: 245–249
18. Yiting Tang, Lan Liu, MingSheng, Kai Xiong Lei Huang, Qian Cao, Jingliang Wei, Tianwen Wu, Shulin Yang, HonglinLiu*, Yulian Mu, Kui Li. Wip1 knochout inhibits the proliferation andenhances the migration of bone marrow mesenchymal stem cells. Experimental CellReseach, 2015, 334: 310-322
19. Liu ZQ,Shen M,Wu WJ,Li BJ,Weng QN,Li M,Liu HL*. Expression of PUMA in folicular granulosa cells regulated by FoxO1activation during oxidative stress. Reprod Sci, 2015, 22(6): 696-705
20. Ma XS, Chao SB, Huang XJ, LinF, Qin L, Wang XG, Meng TG, Zhu CC, Schatten H, Liu HL*, Sun QY*. TheDynamics and Regulatory Mechanism of Pronuclear H3k9me2 Asymmetry in MouseZygotes. Sci Rep. 2015, 5: 17924.
21. Cao R, Wu WJ, Zhou XL, Xiao P,Wang Y, Liu HL*. Expression and preliminary functional profiling of thelet-7 family during porcine ovary follicle atresia. Mol Cells. 2015, 38(4):304-11.
22. Yiting Tang, Kai Xiong, MingShen, Yulian Mu, Kui Li, Honglin Liu*. CCAAT-enhancer binding protein(C/EBP) β regulates insulin-like growth factor (IGF) 1 expression in porcineliver during prenatal and postnatal development. Mol Cell Biochem, 2015,401: 209-218
23. Wangjun Wu, Jing Han, Rui Cao,Jinbi Zhang, Baojiang Li, Zequn Liu, Karqing Liu, Qifa Li, Zengxiang Pan, JieChen, Honglin Liu*. Sequence and regulation of the porcine FSHR genepromoter. Animal Reproduction Science, 2105, 154: 95-104
24. Cao R, Wu W, Zhou X, Liu K, LiB, Huang X, Zhang Y, Liu H*. Let-7g?induces?granulosa cell?apoptosis bytargeting MAP3K1 in the porcine ovary. Int J BiochemCellBiol, 2015, 68:148-57
25. Jilong Zhou, Jiying Liu,Zengxiang Pan, Xing Du, Xinyu Li, Baiquan Ma, Wang Yao Qifa Li, Honglin Liu*. The let-7g microRNA promotes follicular granulosa cellapoptosis by targeting transforming growth factor-β type 1 receptor. Molecularand Cellular Endocrinology, 2015, 409: 103-112