Karl Wah Keung TSIM
詹华强
PhD in Molecular Neurobiology
University of Cambridge, 1988
Chair Professor
Division of Life Science
Director of Center for Chinese Medicine Research and Development
Director of HKUST Shenzhen Center for Chinese Medicine
(852) 2358 7332
botsim@ust.hk
Room 5456
Personal Web
ORCID
0000-0003-4808-1674
Scopus ID
7005540283
Research Interest Publications Projects Teaching Assignment RPG Supervision Space used
Research Interest
Agricultural and domestic animal services
Cellular and molecular mechanisms
Food science and technology
Molecular and cellular neuroscience
Publications
All Years 672 2022 0 2021 35 2020 29 2019 46 2018 50 2017 18 2016 494
2021 35
A prepared platelet-rich plasma extract, namely Self-Growth Colony, inhibits melanogenesis by down-regulating microphthalmia-associated transcription factor in skin melanocyte
Journal of Cosmetic Dermatology, v. 20, (10), 25 April 2021, p. 3278-3288
Guo, Maggie Suisui; Wu, Qiyun; Lai, Queenie Wing Sze; Wang, Xiaoyang; Bai, Panzhu; Fung, Wing Chi; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
A specific and bioactive polysaccharide marker for Cordyceps
Carbohydrate Polymers, v. 269, October 2021, article number 118343
Li, Li-Feng; But, Grace Wing-Chiu; Zhang, Quan-Wei; Liu, Man; Chen, Miao-Miao; Wen, Xin; Wu, Hoi-Yan; Cheng, Hui-Yuan; Puno, Pema-Tenzin; Zhang, Ji-Xia; Fung, Hau-Yee; Bai, Su-Ping; Wong, Tin-Long; Zhao, Zhong-Zhen; Cao, Hui; Tsim, Karl Wah Keung; Shaw, Pang-Chui; Han, Quan-Bin; Sun, Han-Dong Article
An optimized extract, named Self-Growth Colony, from platelet-rich plasma shows robust skin rejuvenation and anti-ageing properties: a novel technology in development of cosmetics
Skin Pharmacology and Physiology, v. 34, (2), April 2021, p. 74-85
Chan, Kar Lun Gallant; Guo, Suisui Maggie; Dai, Kun; Lai, Wing Sze; Fung, Wing Chi; Zheng, Zhongyu; Wu, Qiyun; Man, King Ki; Dong, Tingxia; Tsim, Karl Wah Keung Article
Astragaloside IV, a saponin from Astragalus membranaceus var. mongholicus, induces expressions of heme recycle proteins via signaling of Nrf2/ARE in cultured macrophages
Journal of Ethnopharmacology, v. 265, 30 January 2021, article number 113389
Gong, Guowei; Yu, Huiru; Zheng, Yuzhong; Qi, Baohui; He, Huan; Yin, Tianpeng; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Biological Evaluation and Transcriptomic Analysis of Corylin as an Inhibitor of Osteoclast Differentiation
International Journal of Molecular Sciences, v. 22, (7), March 2021, article number 3540, p. 1-18
Yu, Xiaodan; Xiao, Jian; Zhao, Shizheng; Kong, Xiang-Peng; Kwan, Kin Leung; Zheng, Zhongyu; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung Article
Copper promoting oyster larval growth and settlement: Molecular insights from RNA-seq
Science of The Total Environment, v. 784, August 2021, article number 147159
Li, Yunlong; Tsim, Wah-Keung; Wang, Wen-Xiong Article
Danggui Buxue Tang, a Chinese herbal decoction containing Astragali Radix and Angelicae Sinensis Radix, improves mitochrondial bioenergetics in osteoblast
Phytomedicine, v. 88, July 2021, article number 153605
Kwan, Kin Leung; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Dimeric Tacrine(10)-hupyridone as a Multitarget-Directed Ligand to Treat Alzheimer's Disease
ACS Chemical Neuroscience, v. 12, (13), July 2021, p. 2462-2477
Xuan, Zhenquan; Gu, Xinmei; Yan, Sicheng; Xie, Yanfei; Zhou, Yiying; Zhang, Hui; Jin, Haibo; Hu, Shengquan; Mak, Marvin S.H.; Zhou, Dongsheng; Tsim, Karl Wah Keung; Carlier, Paul R.; Han, Yifan; Cui, Wei Article
Edible Bird's Nest, an Asian Health Food Supplement, Possesses Moisturizing Effect by Regulating Expression of Filaggrin in Skin Keratinocyte
Frontiers in Pharmacology, v. 12, 20 July 2021, article number 685982
Lai, Wing Sze; Guo, Suisui; Wu, Qiyun; Liao, Zhitao; Guan, Dongshi; Dong, Tingxia; Tong, Penger; Tsim, Karl Wah Keung Article
Feeding containing the aerial part of Scutellaria baicalensis promotes the growth and nutritive value of rabbit fish Siganus fuscescens
Food Science and Nutrition, 28 July 2021
Xia, Yiteng; Cheng, Hok Chi; Zheng, Zhongyu; Wu, Qiyun; Dong, Ting Xia; Duan, Ran; Qin, Qi Wei; Wang, Wenxiong; Tsim, Karl Wah Keung Article
Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer
Phytomedicine, v. 80, January 2021, article number 153370
Lou, Jian Shu; Zhao, Li Ping; Huang, Zhi Hui; Chen, Xia Yin; Xu, Jing Ting; Tai, William Chi Shing; Tsim, Karl Wah Keung; Chen, Yi Tao; Xie, Tian Article
Ginsenosides attenuate bioenergetics and morphology of mitochondria in cultured PC12 cells under the insult of amyloid beta-peptide
Journal of Ginseng Research, v. 45, (4), July 2021, p. 473-481
Kwan, Kin Leung; Yun, Huang; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Integrated Omics Reveals the Orchestrating Role of Calycosin in Danggui Buxue Tang, a Herbal Formula Containing Angelicae Sinensis Radix and Astragali Radix, in Inducing Osteoblastic Differentiation and Proliferation
Frontiers in Pharmacology, v. 12, June 2021, article number 670947
Kwan, Kin Leung; Wong, Tin Yan; Yu, Xiaodan; Dong, Ting Xia; Lam, Hei Ning; Tsim, Karl Wah Keung Article
Luteolin stimulates the NGF-induced neurite outgrowth in cultured PC12 cells through binding with NGF and potentiating its receptor signaling
Food & Function, v. 12, (22), 15 November 2021, p. 11525-11525
Gao, Alex Xiong; Xia, Tracy Chen-Xi; Mak, Marvin Shing-Hung; Kwan, Kenneth Kin-Leung; Zheng, Brody Zhong-Yu; Xiao, Jian; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung Article
Mass spectrometry-based multi-omics analysis reveals the thermogenetic regulation of herbal medicine in rat model of yeast-induced fever
Journal of Ethnopharmacology, v. 279, October 2021, article number 114382
Kwan, Kin Leung; Wong, Tin Yan; Wu, Qiyun; Dong, Ting Xia; Lam, Hei Ning; Tsim, Karl Wah Keung Article
Promising tacrine/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget
Journal of Neurochemistry, July 2021
Mak, Shing Hung; Li, Wenming; Fu, Hongjun; Luo, Jialie; Cui, Wei; Hu, Shengquan; Pang, Yuanping; Carlier, Paul R.; Tsim, Karl Wah Keung; Pi, Rongbiao; Han, Yifan Article
The binding of kaempferol-3-O-rutinoside to vascular endothelial growth factor potentiates anti-inflammatory efficiencies in lipopolysaccharide-treated mouse macrophage RAW264.7 cells
Phytomedicine, v. 80, January 2021, article number 153400
Hu, Weihui; Dai, Kun; Zheng, Zhongyu; Duan, Ran; Chan, Kar Lun Gallant; Dong, Ting Xia; Qin, Qi Wei; Tsim, Karl Wah Keung Article
The Mechanisms of Yu Ping Feng San in Tracking the Cisplatin-Resistance by Regulating ATP-Binding Cassette Transporter and Glutathione S-Transferase in Lung Cancer Cells
Frontiers in Pharmacology, v. 12, May 2021, article number 678126
Du, Yingqing; Zheng, Yuzhong; Yu, Ciel Xiaomei; Zhong, Lishan; Li, Yafang; Wu, Baomeng; Hu, Weihui; Zhu, Elsa Wanyi; Xie, Venus Wei; Xu, Qitian; Zhan, Xingri; Huang, Yamiao; Zeng, Liyi; Zhang, Zhenxia; Liu, Xi; Yin, Jiachuan; Zha, Guangcai; Chan, Kelvin; Tsim, Karl Wah Keung Article
The osteogenic function of danggui buxue tang, a herbal decoction containing astragali radix and angelicae sinensis radix, is optimized by boiling the two herbs together: Signaling analyses revealed by systems biology
Processes, v. 9, (7), July 2021, article number 1119
Kwan, Kin Leung; Wong, Tin Yan; Yu, Xiaodan; Dong, Ting Xia; Lam, Hei Ning; Tsim, Karl Wah Keung Article
Trewioidesine A, an Unsaturated Fatty Acid from Rhizomes of Alchornea Trewioides, Shows Synergy with NGF in Inducing Differentiation of Pheochromocytoma PC12 Cells
Natural Product Research, 16 September 2021
Peng, Zhi-Tian; Gao, Xiong; Huo, Hui-Xia; Wang, Huai-You; Guo, Qing-Bo; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung Article
Unique interplay between Zn2+ and nZnO determined the dynamic cellular stress in zebrafish cells
Environmental Science: Nano, v. 8, (8), August 2021, p. 2324-2335
Sun, Anqi; Tang, Benzhong; Tsim, Karl Wah Keung; Wang, Wen Xiong Article
Phytocosmetics and Cosmetic Science
Phytocosmetics and Cosmetic Science / Edited By Nattaya Lourith, Karl Wah-Keung Tsim. CRC Press, 2021
Lourith, Nattaya; Tsim, Karl Wah Keung Book
Phytocosmetics Derived from Traditional Chinese Medicine
Phytocosmetics and Cosmetic Science / Edited by Nattaya Lourith and Karl W. K. Tsim. Boca Raton, USA : CRC Press, 2021, p. 9-21
Wu, Qiyun; Lai, Wing Sze; Guo, Suisui; Tsim, Karl Wah Keung Book chapter
A screening platform of Chinese medicine in activating Wnt/β-catenin signaling pathway in cultured human embryonic kidney 293T cells: development of health food supplement for hair growth
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Yuen, Ka Wing Gary; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
A screening platform of traditional Thai medicine in inhibiting β-amyloid aggregation pathway: drug development for against Alzheimer’s disease
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Ospondpant, Dusadee; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Anti-bacterial effect of traditional Chinese medicine prepared in nano drug delivery system: potential application in aquaculture feedings
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Cheng, Hok Chi; Xia, Yiteng; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Edible bird's nests improve skin barrier functions through moisturization and anti-inflammation
The 17th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 13 August 2021
Lai, Wing Sze; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Luteolin stimulates NGF-induced neurite outgrowth in cultured PC12 cells through binding with NGF and upregulated reactive oxygen species
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Gao, Xiong; Xia, Chenxi; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Screening traditional Chinese medicine in promoting fish growth by using growth hormone-IGF1 signaling in HEK293T cells
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Zhang, Hoi Lam; Xia, Yiteng; Cheng, Hok Chi; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Scutellarin, a flavonoid from Scutellaira barbata, enhances growth factors activity on VEGFR and MAPK signaling during wound repair in HaCaT keratinocytes
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Guo, Suisui; Gao, Xiong; Wang, Xiaoyang; Hu, Weihui; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Sea buckthorn flavonoids potentiate NGF-induced neuronal differentiation
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Xia, Chenxi; Gao, Xiong; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
The anti-neuroinflammatory effects of berberine and palmatine by targeting on AChE and α7 nAChR
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Xia, Yingjie; Kong, Xiangpeng; Wu, Qiyun; Xia, Yiteng; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
The extract from aerial part of Scutellaria baicalensis as a feeding additive regulates gut microbiota and promotes the growth of Siganus fuscescens
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Xia, Yiteng; Wu, Qiyun; Cheng, Hok Chi; Dong, Tingxia; Qin, Qiwei; Wang, Wenxiong; Tsim, Karl Wah Keung Conference paper
Traditional Chinese medicine promotes the anti-inflammatory effect of probiotics in fighting against skin eczema
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Chen, Yanxian; Zheng, Zhongyu; Leung, Ka Wing; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Traditional Chinese medicine protects E. coli from anti-depressants-induced mutation of having resistance to antibiotics
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Wu, Jiahui; Dong, Tingxia; Wang, Huaiyou; Tsim, Karl Wah Keung Conference paper
2020 29
A Review of Edible Jujube, the Ziziphus jujuba Fruit: A Heath Food Supplement for Anemia Prevalence
Frontiers in Pharmacology, v. 11, November 2020, article number 593655
Chen, Jianping; Tsim, Karl Wah Keung Article
A standardized extract of Danggui Buxue Tang decoction selectively exerts estrogenic activities distinctly from tamoxifen
Phytotherapy Research, v. 35, (3), March 2021, p. 1456-1467
Zhou, Liping; Wong, Ka-Ying; Cao, Sisi; Poon, Christina Chui-Wa; Yu, Wenxuan; Dong, Xiaoli; Tsim, Karl Wah Keung; Wong, Man-Sau Article
Capsaicin Inhibits the Expression of Melanogenic Proteins in Melanocyte via Activation of TRPV1 Channel: Identifying an Inhibitor of Skin Melanogenesis
Journal of Agricultural and Food Chemistry, v. 68, (50), 16 December 2020, p. 14863-14873
Wu, Qiyun; Bai, Panzhu; Xia, Yiteng; Xia, Yingjie; Xu, Bowen; Dai, Kun; Zheng, Zhongyu; Guo, Suisui; Fung, Wing Chi; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Corylin, a flavonoid derived from Psoralea Fructus, induces osteoblastic differentiation via estrogen and Wnt/β-catenin signaling pathways
FASEB Journal, v. 34, (3), March 2020, p. 4311-4328
Yu, Xiaodan; Xu, Li Miranda; Yao, Ping; Kwan, Kin Leung; Liu, Yongxiang; Duan, Ran; Dong Ting Xia; Ko, Kam Ming; Tsim, Karl Wah Keung Article
Dehydrocorydaline Accounts the Majority of Anti-Inflammatory Property of Corydalis Rhizoma in Cultured Macrophage
Evidence-based Complementary and Alternative Medicine, v. 2020, November 2020, article number 4181696
Kong, Xiangpeng; Chen, Zhicong; Xia, Yingjie; Liu, Yunle; Ren, Haiqin; Wang, Cheng; Hu, Weihui; Dong, Ting Xia; Pi, Rongbiao; Tsim, Karl Wah Keung Article
Design, Synthesis, and Biological Evaluation of Novel Multifunctional Rolipram-Tranilast Hybrids As Potential Treatment for Traumatic Brain Injury
ACS Chemical Neuroscience, v. 11, (15), 9 July 2020, p. 2348-2360
Lu, Junfeng; Chen, Chen; Deng, Xiaobing; Mak, Marvin SH; Zhu, Zeyu; He, Xixin; Liang, Jinhao; Maddili, Swetha Kameswari; Tsim, Karl Wah Keung; Han, Yifan; Pi, Rongbiao Article
Discovery of a Novel Small Molecule PT109 With Multi-Targeted Effects Against Alzheimer's Disease in Vitro and in Vivo
European Journal of Pharmacology, v. 883, 15 September 2020, article number 173361
Chen, Qiuhe; Tu, Yalin; Mak, Shinghung; Chen, Jingkao; Lu, Junfeng; Chen, Chen; Yang, Xiaohong; Wang, Shengnan; Wen, Shijun; Ma, Shanshan; Li, Mingtao; Han, Yifan; Tsim, Karl Wah Keung; Pi, Rongbiao Article
Evaluation of Anti-Inflammatory Components of Guizhi Fuling Capsule, an Ancient Chinese Herbal Formula, in Human Umbilical Vein Endothelial Cells
Evidence-based Complementary and Alternative Medicine, v. 2020, October 2020, article number 2029134
Zheng, Yuzhong; Xin, Guizhong; Gong, Guowei; Dong, Tingxia; Li, Ping; Tsim, Karl Wah Keung Article
Fermentation of Danggui Buxue Tang, an ancient Chinese herbal mixture, together with Lactobacillus plantarum enhances the anti-diabetic functions of herbal product
Chinese Medicine (United Kingdom), v. 154, (1), 11 September 2020, article number 98
Guo, Rui; Guo, Shuchen; Gao, Xiong; Wang, Huaiyou; Hu, Weihui; Duan, Ran; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Integrated Assessment of Medicinal Rhubarb by Combination of Delayed Luminescence and HPLC Fingerprint With Emphasized on Bioactivities Based Quality Control
Chinese Medicine (United Kingdom), v. 15, (1), July 2020, article number 72
Sun, Mengmeng; Wu, Hongwei; He, Min; Jia, Yusheng; Wang, Lixue; Liu, Ting; Hui, Lianqiang; Li, Li; Wei, Shengli; Van Wijk, Eduard; Van Wijk, Roeland; Tsim, Karl Wah Keung; Li, Chun; Wang, Mei Article
Integration of Organ Metabolomics and Proteomics in Exploring the Blood Enriching Mechanism of Danggui Buxue Decoction in Hemorrhagic Anemia Rats
Journal of Ethnopharmacology, v. 261, 28 October 2020, article number 113000
Shi, Xuqin; Zhu, Zhenhua; Yue, Shijun; Tang, Yuping; Chen, Yanyan; Pu, Zongjin; Tao, Huijuan; Zhou, Guisheng; Yang, Ye; Guo, Mengjie; Dong, Ting Xia Tina; Tsim, Karl Wah Keung; Duan, Jinao Article
Interacting with α7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages
Acta Pharmaceutica Sinica B, v. 10, (10), October 2020, p. 1926-1942
Liu, Yunle; Xia, Yingjie; Kong, Xiangpeng; Guo, Suisui; Yu, Xiaodan Anna; Zheng, Zhongyu; Mak, Shing Hung; Xu, Li; Tsim, Karl Wah Keung Article
Jellyfish genomes reveal distinct homeobox gene clusters and conservation of small RNA processing
Nature Communications, v. 11, (1), December 2020, article number 3051
Nong, Wenyan; Cao, Jianquan; Li, Yiqian; Qu, Zhe; Sun, Jin; Swale, Thomas; Yip, Ho Yin; Qian, Peiyuan; Qiu, Jian-Wen; Kwan, Hoi Shan; Bendena, William; Tobe, Stephen; Chan, Ting Fung; Yip, Kevin Y.; Chu, Ka Hou; Ngai, Sai Ming; Tsim, Karl Wah Keung; Holland, Peter W.H.; Hui, Jerome H.L. Article
Kaempferol, a Major Flavonoid in Ginkgo Folium, Potentiates Angiogenic Functions in Cultured Endothelial Cells by Binding to Vascular Endothelial Growth Factor
Frontiers in Pharmacology, v. 11, April 2020, article number 526
Hu, Weihui; Wang, Huai-You; Xia, Yiteng; Dai, Diana Kun; Xiong, Qing-Ping; Dong, Tina Ting-Xia; Duan, Ran; Chan, Kar Lun Gallant; Qin, Qi-Wei; Tsim, Wah-Keung Article
Piceatannol, a Natural Analog of Resveratrol, Exerts Anti-angiogenic Efficiencies by Blockage of Vascular Endothelial Growth Factor Binding to Its Receptor
Molecules, v. 25, (17), August 2020, article number 3769
Hu, Weihui; Dai, Kun; Zheng, Zhongyu; Duan, Ran; Dong, Tingxia; Qin, Q.-W.; Tsim, Karl Wah Keung Article
Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties
Frontiers in Pharmacology, v. 10, January 2020, article number 1549
Gong, Guowei; Huang, Jing; Yang, Yang; Qi, Baohui; Han, Guangyi; Zheng, Yuzhong; He, Huan; Chan, Kelvin; Tsim, Karl Wah Keung; Dong, Tingxia Article
Shexiang Baoxin Pill, a Traditional Chinese Herbal Formula, Rescues the Cognitive Impairments in APP/PS1 Transgenic Mice
Frontiers in Pharmacology, v. 11, July 2020, article number 1045
Hu, Weihui; Mak, Shing Hung; Zheng, Zhongyu; Xia, Yingjie; Xu, Miranda Li; Duan, Ran; Dong, Ting Xia; Li, Shao-Ping; Zhan, Chang-Sen; Shang, Xiao-Hui; Tsim, Karl Wah Keung Article
Significant combination of Aβ aggregation inhibitory and neuroprotective properties in silico, in vitro and in vivo by bis(propyl)-cognitin, a multifunctional anti-Alzheimer’s agent
European Journal of Pharmacology, v. 876, 5 June 2020, article number 173065
Hu, Shengquan; Xian, Yanfang; Fan, Yubo; Mak, Shinghung; Wang, Jiajun; Tang, Jing; Pang, Yuanping; Pi, Rongbiao; Tsim, Karl Wah Keung; Liu, Fufeng; Lin, Zhixiu; Han, Yifan Article
Solar light induces expression of acetylcholinesterase in skin keratinocytes: Signalling mediated by activator protein 1 transcription factor
Neurochemistry International, v. 141, December 2020, article number 104861
Wu, Qiyun; Bai, Panzhu; Xia, Yingjie; Queenie W. S. Lai; Guo, Maggie S. S.; Dai, Kun; Zheng, Zhongyu; Ling, Christine S. J.; Dong, Tina T. X.; Pi, Rongbiao; Tsim, Karl Wah Keung Article
Solar light induces the release of acetylcholine from skin keratinocytes affecting melanogenesis
FASEB Journal, v. 34, (7), July 2020, p. 8941-8958
Wu, Qiyun; Xia, Yiteng; Dai, Kun; Bai, Panzhu; Kwan, Kenneth K. L; Guo, Maggie S.S.; Dong, Tina T.X.; Tsim, Karl Wah Keung Article
The anti-bacterial effects of aerial parts of Scutellaria baicalensis: Potential application as an additive in aquaculture feedings
Aquaculture, v. 526, September 2020, article number 735418
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Duan, Ran; Hu, Weihui; Qin, Qi-Wei; Wang, Wenxiong; Tsim, Karl Wah Keung Article
The Chinese Medicinal Herbs of Spleen-meridian Property Regulate Body Temperature in Yeast-induced Fever Rats
Phytomedicine, v. 74, August 2020, article number 152815
Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiangpeng; Dong, Ting Xia; Chen, Yicun; Qin, Qiwei; Tsim, Karl Wah Keung Article
The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix
Molecules, v. 25, (24), December 2020, article number 5914
Kong, Xiangpeng; Ren, Haiqin; Liu, Yunle; Leung, Ka Wing; Guo, Shuchen; Duan, Ran; Dong, Ting Xia; Tsim, Karl Wah Keung Article
The Herbal Extract Deriving From Aerial Parts of Scutellaria Baicalensis Shows Anti-inflammation and Anti-hypoxia Responses in Cultured Fin Cells From Rabbit Fish
Fish & Shellfish Immunology, v. 106, November 2020, p. 71-78
Xia, Yiteng; Hu, Weihui; Wu, Qiyun; Dong, Tingxia Tina; Duan, Ran; Xiao, Jian; Li, Shaoping; Wang, Wenxiong; Qin, Qiwei; Tsim, Karl Wah Keung Article
发酵柴胡地上部分定量分析及其抗菌活性成分预测
中国中药杂志=China Journal of Chinese Materia Medica, v. 45, (17), September 2020, p. 4238-4245
郭舒臣; 郭瑞; 夏翊腾; 董婷霞; 王怀友; 詹华强 Article
Corylin inhibits RANKL-induced osteoclastogenesis: signaling mediated by NF-κB pathways and direct target identification
30th Australian & New Zealand Bone and mineral Society Annual Scientific Meeting, Virtual Meeting, 12-14 October 2020
Yu, Xiaodan; Kong, Xiangpeng; Zhao, Shizheng; Kwan, Kenneth Kin-Leung; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung Conference paper
Edible Bird’s Nests Promote Skin Hydration through Skin Barrier Protection
The 16th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2020
Lai, Wing Sze; Chan, Kar Lun Gallant; Wu, Qiyun; Wong, Chun Fai; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Integrated omics dissection of the effect of natural product decoction on cultured osteoblasts
8th Asia-Oceania Mass Spectrometry Conference (AOMSC 2020), Macau, China, 5-7 January 2020
Kwan, Kin Leung; Tsim, Karl Wah Keung; Lam, Henry Conference paper
Multi-omics investigation of synergistic effects of traditional Chinese medicine herbal decoction on cultured osteoblasts
68th American Society for Mass Spectrometry Conference (ASMS Reboot 2020), Online, 1-12 June 2020
Kwan, Kin Leung; Wong, Tin Yan; Yu, Anna Xiaodan; Dong, Tingxia; Lam, Henry Hei Ning; Tsim, Karl Wah Keung Conference paper
2019 46
Activation of G Protein-Coupled Receptor 30 by Flavonoids Leads to Expression of Acetylcholinesterase in Cultured PC12?Cells
Chemico-Biological Interactions, v. 306, June 2019, p. 147-151
Liu, Yunle; Xu, Miranda Li; Xia, Yingjie; Kong, Xiangpeng; Wu, Qiyun; Dong, Tingxia Ting Xia; Tsim, Karl Wah Keung Article
An Ancient Chinese Herbal Decoction Containing Angelicae Sinensis Radix, Astragali Radix, Jujuba Fructus, and Zingiberis Rhizoma Recens Stimulates the Browning Conversion of White Adipocyte in Cultured 3T3-L1 Cells
Evidence-based Complementary and Alternative Medicine, v. 2019, June 2019, article number 3648685
Gong, Guowei; Han, Guangyi; He, Huan; Dong, Tina T. X.; Tsim, Karl Wah Keung; Zheng, Yuzhong Article
An Optimization of Ultra-sonication-assisted Extraction From Flowers of Apocynum Venetum in Targeting to Amount of Free Amino Acids Determined by UPLC-MS/MS
Food Quality and Safety, v. 3, (1), 11 April 2019, p. 52-60
Jin, Yan; Wang, Caroline Yang; Hu, Weihui; Huang, Yun; Xu, Li; Wang, Huaiyou; Kong, Xiangpeng; Chen, Yicun; Dong, Tingxia; Qin, Qiwei; Tsim, Karl Wah Keung Article
Asarones From Acori Tatarinowii Rhizoma Stimulate Expression and Secretion of Neurotrophic Factors in Cultured Astrocytes
Neuroscience Letters, v. 707, August 2019, article number 134308
Lam, Yin Ching; Wu, Qiyun; Hu, Weihui; Yao, Ping; Wang, Huai-You; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Binding of Resveratrol to Vascular Endothelial Growth Factor Suppresses Angiogenesis by Inhibiting the Receptor Signaling
Journal of Agricultural and Food Chemistry, v. 67, (4), January 2019, p. 1127-1137
Hu, Weihui; Duan, Ran; Xia, Yiteng; Xiong, Qing-Ping; Wang, Huai-You; Chan, Kar Lun Gallant; Liu, Si-Yue; Dong, Ting Xia; Qin, Qi-Wei; Tsim, Karl Wah Keung Article
Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, Modulates Mitochondrial Bioenergetics in Cultured Cardiomyoblasts
Frontiers in Pharmacology, v. 10, (JUN), June 2019, article number 614
Kwan, Kin Leung; Huang, Yun; Leung, Ka Wing; Dong, Tina Xia; Tsim, Karl Wah Keung Article
Danggui Buxue Tang, an ancient Chinese herbal decoction, protects β-amyloid-induced cell death in cultured cortical neurons
BMC Complementary and Alternative Medicine, v. 19, (1), January 2019, article number 9
Gong, Guowei; Qi, Baohui; Liang, Yanting; Dong, Ting Xia; Wang, Huai you; Tsim, Karl Wah Keung; Zheng, Yuzhong Article
Differentiation of Erythroblast Requires the Dimeric Form of Acetylcholinesterase: Interference With Erythropoietin Receptor
Chemico-Biological Interactions, v. 308, August 2019, p. 317-322
Xua, Miranda L.; Luk, Wilson K. W.; Liu, Yunle; Kong, Xiang P.; Wu, Qi Y.; Xia, Yingjie; Dong, Tina T. X.; Tsim, Karl Wah Keung Article
Isoorientin Derived from Gentiana Veitchiorum Hemsl. Flowers Inhibits Melanogenesis by Down-regulating MITF-induced Tyrosinase Expression
Phytomedicine, v. 57, April 2019, p. 129-136
Wu, Qiyun; Wong, Chun Fai; Wang, Cheng; Fung, Hei Yiu; Wong, Oi Ying; Chan, Kar Lun Gallant; Dong, Tina Ting-Xia; Chen, Yicun; Tsim, Karl Wah Keung Article
Isorhynchophylline Ameliorates Cognitive Impairment via Modulating Amyloid Pathology, Tau Hyperphosphorylation and Neuroinflammation: Studies in a Transgenic Mouse Model of Alzheimer's Disease
Brain, Behavior, and Immunity, v. 82, November 2019, p. 264-278
Li, Huiqin; Ip, Siu Po; Yuan, Qiuju; Zheng, Guoqing; Tsim, Karl Wah Keung; Dong, Ting Xia; Lin, Ge; Han, Yifan; Liu, Yue; Xian, Yanfang; Lin, Zhixiu Article
Molecular characteristics and function study of TNF receptor-associated factor 5 from grouper (Epinephelus coioides)
Fish and Shellfish Immunology, v. 87, April 2019, p. 730-736
Yang, Man; Han, Rui; Ni, Luyun; Luo, Xiaochun; Li, Anxing; Dan, Xueming; Tsim, Karl Wah Keung; Li, Yanwei Article
Ophiopogon Polysaccharide Promotes the In Vitro Metabolism of Ophiopogonins by Human Gut Microbiota
Molecules, v. 24, (16), 8 August 2019, article number 2886
Wang, Huaiyou; Guo, Shuchen; Peng, Zhitian; Wang, Cheng; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung Article
Polydatin Suppresses VEGF-induced Angiogenesis Through Binding with VEGF and Inhibiting Its Receptor Signaling
FASEB Journal, v. 33, (1), January 2019, p. 532-544
Hu, Weihui; Wang, Huaiyou; Kong, Xiang-Peng; Xiong, Qingping; Poon, Ka Man; Xu, Li; Duan, Ran; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung Article
Polysaccharide deriving from Ophiopogonis Radix promotes metabolism of ginsenosides in the present of human gut microbiota based on UPLC-MS/MS assay
Journal of Pharmaceutical and Biomedical Analysis, v. 175, 25 October 2019, article number 112779
Wang, Huaiyou; Wang, Cheng; Guo, Shuchen; Chen, Zhicong; Peng, Zhitian; Duan, Ran; Dong, T.T.X.; Tsim, Karl Wah Keung Article
Polysaccharide From Tuberous Roots of Ophiopogon japonicus Regulates Gut Microbiota and Its Metabolites During Alleviation of High-fat Diet-induced Type-2 Diabetes in Mice
Journal of Functional Foods, v. 63, December 2019, article number 103593
Wang, Huaiyou; Guo, Linxiu; Hu, Weihui; Peng, Zhitian; Wang, Cheng; Chen, Zhicong; Liu, Yunle; Dong, Ting Xia; Wang, Tiejie; Tsim, Karl Wah Keung Article
Shexiang Baoxin Pill, A Formulated Chinese Herbal Mixture, Induces Neuronal Differentiation of PC12 Cells: A Signaling Triggered by Activation of Protein Kinase A
Frontiers in Pharmacology, v. 10, October 2019, article number e01130
Xu, Miranda Li; Zheng, Zhongyu; Xia, Yingjie; Liu, Yunle; Chan, Stanley Ka Ho; Hu, Weihui; Duan, Ran; Dong, Tina Tingxia; Zhan, Chang-Sen; Shang, Xiao-Hui; Tsim, Karl Wah-Keung Article
Simultaneous Determination of Short-chain Fatty Acids in Human Feces by HPLC With Ultraviolet Detection Following Chemical Derivatization and Solid-phase Extraction Segmental Elution
Journal of Separation Science, v. 42, (15), August 2019, p. 2500-2509
Wang, Huai You; Wang, Cheng; Guo, Linxiu; Zheng, Yunfeng; Hu, Weihui; Dong, Tingxia; Wang, Tiejie; Tsim, Karl Wah Keung Article
Synergistic inhibition of acetylcholinesterase by alkaloids derived from Stephaniae tetrandrae radix, Coptidis rhizoma and Phellodendri chinensis cortex
Molecules, v.24, (24), December 2019, article number 4567
Kong, Xiangpeng; Liu, Etta Yun Le; Chen, Zhicong; Xu, Miranda Li; Yu, Anna X.D.; Wu, Qiyun; Xia, Yingjie; Duan, Ran; Dong,Ting Xia; Tsim, Karl Wah Keung Article
Synergy of ginkgetin and resveratrol in suppressing vegf-induced angiogenesis: A therapy in treating colorectal cancer
Cancers, v. 11, (12), December 2019, article number 1828
Hu, Weihui; Chan, Kar Lun Gallant; Duan, Ran; Wang, Huaiyou; Kong, Xiangpeng; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Tectorigenin, an isoflavone aglycone from the rhizome of Belamcanda chinensis, induces neuronal expression of erythropoietin via accumulation of hypoxia-inducible factor-1α
Phytotherapy Research, 2019
Liu, Etta Y.; Zheng, Zoey X.; Zheng, Brody Z.; Xia, Yingjie; Guo, Maggie S.; Dong, Tina T.; Tsim, Karl Wah Keung Article
The effect of methanol extract from Saussurea involucrata in the lipopolysaccharide-stimulated inflammation in cultured RAW 264.7 cells
Journal of Ethnopharmacology, v. 251, article number 112532
Gong, Guowei; Xie, Feng; Zheng, Yuzhong; Hu, Weihui; Qi, Baohui; He, Huan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
The Effects of Shexiang Baoxin Pill in Alzheimer’s Disease and Inflammation
Research on Pharmacology, v. 1, (1), September 2019, p. 1-14
Xia, Yingjie; Xu, Li; Zheng, Zhongyu; Zhan, Changsen; Shang, Xiaohui; Dong, Tingxia; Hu, Weihui; Chan, Ka Ho; Duan, Ran; Tsim, Karl Wah Keung Article
UPLC-MS/MS法与HPLC-FLD法分析检测中药中的黄曲霉毒素
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 39, (7), 2019, p. 1272-1278
郭舒臣; 汪成; 彭治添; 董婷霞; 詹华强 Article
毛冬青质量标准的改进研究
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 39, (8), 2019, p. 1416-1424
王怀友; 汪成; 郑玉忠; 邓伟麟; 段然; 董婷霞; 詹华强 Article
瓜子金质量标准研究
时珍国医国药=Lishizhen Medicine and Materia Medica Research, v. 30, (9), September 2019, p. 2159-2163
王怀友; 汪成; 郑玉忠; 邓伟麟; 段然; 董婷霞; 詹华强 Article
药对配伍效应与功效物质现代研究方法与策略
药学学报=Acta Pharmaceutica Sinica, v. 54, (9), September 2019, p. 1564-1573
唐于平; 尚尔鑫; 陈艳琰; 乐世俊; 史旭芹; 董婷霞; 詹华强; 段金廒 Article
AChE regulates LPS-induced inflammatory response in macrophages
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Xia, Yingjie; Liu, Yunle; Kong, Xiangpeng; Wu, Qiyun; Guo, Suisui; Zheng, Zhongyu; Mak, Shing Hung; Sui, Yixuan; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Assembly of PRiMA-linked form of acetylcholinesterase in neurons: the role of enzyme inhibitor acting as a chemical chaperon
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Mak, Shing Hung; Liu, Yunle; Xia, Yingjie; Kong, Xiangpeng; Guo, Suisui; Yu, Xiaodan; Zheng, Zhongyu; Duan, Ran; Tsim, Karl Wah Keung Conference paper
Capsaicin inhibits melanogenesis through downregulating tyrosinase expression
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Wu, Qiyun; Bai, Panzhu; Xia, Yiteng; Dai, Kun; Zheng, Zhongyu; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Corylin induces bone differentiation and metabolic profiling: illustration by using cultured osteoblasts and bone micromass
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Yu, Xiaodan; Xu, Li; Yao, Ping; Kwan, Kin Leung; Liu, Yongxiang; Dong, Tingxia; Ko, Kam Ming; Tsim, Karl Wah Keung Conference paper
Fractionation of proteins in identifying and understanding the health-promoting functions of edible bird’s nests
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15 - 16 August 2019
Lai, Wing Sze; Chan, Kar Lun Gallant; Wu, Qiyun; Zheng, Zhongyu; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
HerboChips: a screening platform for drug development from traditional Chinese medicine on a chip
19th International Congress of the International Society for Ethanopharmacology, ISE 2019, Dresden, Germany, 12-14 June 2019
Tsim, Karl Wah Keung; Hu, Weihui; Duan, Ran; Dong, Tingxia; Wang, Huaiyou; Xia, Yiteng Conference paper
Kaempferol, a major flavonoid in Ginkgo Folium, binds to vascular endothelial growth factor and potentiates angiogenic functions in cultured endothelial cells
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Hu, Weihui; Wang, Huaiyou; Duan, Ran; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Kaempferol, a major flavonoid in Ginkgo Folium, binds to vascular endothelial growth factor and potentiates angiogenic functions in cultured endothelial cells
19th International Congress of the International Society for Ethanopharmacology, ISE 2019, Dresden, Germany, 12-14 June 2019
Hu, Weihui; Xia, Yiteng; Duan, Ran; Dong, Tingxia; Wang, Huaiyou; Tsim, Karl Wah Keung Conference paper
Mass spectrometry based omics technology to reveal the effect of herbal decoction in cultured osteoblasts
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Kwan, Kin Leung; Wong, Tin Yan; Yu, Xiaodan; Leung, Ka Wing; Dong, Tingxia; Lam, Hei Ning; Tsim, Karl Wah Keung Conference paper
Mass-Spectrometry-Based Omics Technology to Reveal the Effect of Herbal Decoction in Cultured Osteoblasts
67th ASMS Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, 2-6 June 2019
Kwan, Kin Leung; Wong, Tin Yan; Yu, Xiaodan; Leung, Ka Wing; Dong, Tingxia; Lam, Hei Ning; Tsim, Karl Wah Keung Conference paper
Pharmacological characterizations of multifunctional anti-dementia NMDA receptor antagonist memantine nitrates
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Mak, Shing Hung; Han, Yifan; Zhang, Zaijun; Tsim, Karl Wah Keung Conference paper
Polysaccharide from tuberous roots of Ophiopogon japonicus regulates gut microbiota and its metabolites during alleviation of HFD-induced type-2 diabetes in mice
19th International Congress of the International Society for Ethanopharmacology, ISE 2019, Dresden, Germany, 12-14 June 2019
Wang, Huaiyou; Wang, Cheng; Hu, Weihui; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
SGC - An advance autologous skin rejuvenalim lechnoIogy
Cosmetic and Beauty International Conference 2019 (CBIC 2019): Sustainable Cosmetic and Beauty Innovations, Mae Fah Luang University, Thailand, 7-9 October 2019
Chan, Kar Lun Gallant; Tsim, Karl Wah Keung Conference paper
Sunlight stimulation induces the release of acetylcholine from skin keratinocyte via signaling mediated by opsin
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Wu, Qiyun; Xia, Yiteng; Xia, Yingjie; Bai, Panzhu; Dai, Kun; Chen, Yicun; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The anti-bacterial effects of aerial parts of Scutellaria baicalnsis: potential application as an additive in aquaculture feedings
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Duan, Ran; Qin, Qiwei; Wang, Wenxiong; Tsim, Karl Wah Keung Conference paper
The anti-bacterial effects of aerial parts of Scutellaria baicalnsis: potential application as an additive in aquaculture feedings
19th International Congress of the International Society for Ethanopharmacology, ISE 2019, Dresden, Germany, 12-14 June 2019
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Duan, Ran; Qin, Qiwei; Wang, Wenxiong; Tsim, Karl Wah Keung Conference paper
The anti-inflammatory efficiencies of kaempferol-3-O-rutinoside and donepezil in lipopolysaccharide-treated mouse macrophage RAW264.7 cells
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Hu, Weihui; Duan, Ran; Xia, Yingjie; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The effect of Shexiang Baoxin Pill in Alzheimer’s disease and inflammation
5th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Xia, Yingjie; Xu, Li; Zheng, Zhongyu; Dong, Tingxia; Hu, Weihui; Chan, Ka Ho; Duan, Ran; Tsim, Karl Wah Keung Conference paper
Traditional Chinese medicine as the innovative cosmetics
Cosmetic and Beauty International Conference 2019 (CBIC 2019): Sustainable Cosmetic and Beauty Innovations, Mae Fah Luang University, Thailand, 7-9 October 2019
Tsim, Karl Wah Keung Conference paper
Transcriptional regulation of acetylcholinesterase in skin during melanogenesis: an enzyme in controlling skin color
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Tsim, Karl Wah Keung; Mak, Shing Hung; Wu, Qiyun; Xia, Yingjie; Hu, Weihui; Dong, Tingxia; Duan, Ran; Chen, Yicun Conference paper
2018 50
2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Alterations in Myogenic Differentiation of C2C12 Cells
Environmental Pollution, v.235, April 2018, p. 965-973
Xie, Heidi Q.; Xia, Yingjie; Xu, Tuan; Chen, Yangsheng; Fu, Hualing; Li, Yunping; Luo, Yali; Xu, Li; Tsim, Karl Wah Keung; Zhao, Bin Article
A Chinese herbal decoction, Jian-Pi-Yi-Shen, regulates the expressions of erythropoietin and pro-inflammatory cytokines in cultured cells
BMC Complementary and Alternative Medicine, v. 18, (1), 3 April 2018, article number 119
Chen, jianping; Gong, Guowei; Liu, xiaoyan; Li, Zhonggui; Qi, airong; Dong, tingxia; Yi, tiegang; Tsim, Karl Wah Keung; Li, shunmin Article
A Chinese Herbal Preparation, Xiao-Er-An-Shen Decoction, Exerts Neuron Protection by Modulation of Differentiation and Antioxidant Activity in Cultured PC12 Cells
Evidence-based Complementary and Alternative Medicine, v. 2018, 2018, article number 8670421
Li, Zhonggui; Lam, Yin Ching; Liu, Xiaoyan; Qi, Airong; Yao, Ping; Dong, Tina T. X.; Yi, Tiegang; Tsim, Karl Wah Keung; Chen, Jianping Article
A Comprehensive Proteomics Study on Edible Bird's Nest Using New Monoclonal Antibody Approach And Application In Quality Control
Journal of Food Composition And Analysis, v. 66, March 2018, p. 145-151
Wong, Chun Fai; Chan, Kar Lun Gallant; Wu, Long; Lam, Hei Ning; Yao, Ping; Dong, Tina T. X.; Tsim, Karl Wah Keung Article
An UPLC-MS/MS method for simultaneous determination of multiple constituents in Guizhi Fuling capsule with ultrafast positive/negative ionization switching
Chinese Journal of Natural Medicines, v. 16, (4), April 2018, p. 313-320
Zhang, Rong-Hua; Li, Chao-Ran; Yang, Hua; Li, Meng-Ning; Tsim, Karl Wah Keung; Li, Ping; Gao, Wen Article
Bone Protective Effects of Danggui Buxue Tang Alone and in Combination With Tamoxifen or Raloxifene in vivo and in vitro
Frontiers in Pharmacology, v. 9, 13 August 2018, article number 779
Zhou, Li-Ping; Wong, Ka-Ying; Yeung, Hoi-Ting; Dong, Xiao-Li; Xiao, Hui-Hui; Gong, G. W. Amy; Tsim, Karl Wah Keung; Wong, Man-Sau Article
Calycosin Orchestrates Osteogenesis of Danggui Buxue Tang in Cultured Osteoblasts: Evaluating the Mechanism of Action by Omics and Chemical Knock-out Methodologies
Frontiers in Pharmacology, v. 9, (36), February 2018, article number 36
Gong, Amy G. W.; Duan, Ran; Wang, Huai Y.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Complete digestion of edible bird's nest releases free N-acetylneuraminic acid and small peptides: an efficient method to improve functional properties
Food & Function, v. 9, (10), October 2018, p. 5139-5149
Wong, Chun Fai; Chan, Kar Lun Gallant; Wu, Qiyun; Poon, Ka Man; Chen, Yicun; Dong, Tingxia; Tsim, Karl Wah Keung Article
Discrimination of three Siegesbeckiae Herba species using UPLC-QTOF/MS-based metabolomics approach
Food and Chemical Toxicology, v. 119, September 2018, p. 400-406
Tao, Hong-Xun; Xiong, Wei; Zhao, Guan-Ding; Peng, Yu; Zhong, Zhang-Feng; Xu, Liiang; Duan, Ran; Tsim, Karl Wah Keung; Yu, Hua; Wang, Yi-Tao Article
Erythropoietin Regulates The Expression of Dimeric Form of Acetylcholinesterase During Differentiation of Erythroblast
Journal of Neurochemistry, v. 146, April 2018, article number 14448, p. 390-402
Xu, Li; Luk, Kin Wai Wilson; Bi, Wenchuan; Liu, Yunle; Wu, Qiyun; Yao, Ping; Dong, tingxia; Tsim, Karl Wah Keung Article
Evaluation of the Pharmaceutical Properties and Value of Astragali Radix
Medicines (Basel)., v. 5, (2), 21 May 2018, article number 46
Gong, Guowei; Duan, Ran; Wang, Huaiyou; Kong, xiang; Dong, Tingxia; Tsim, Karl Wah Keung; Chan, Kelvin Article
Flavonoids are identified from the extract of Scutellariae Radix to suppress inflammatory-induced angiogenic responses in cultured RAW 264.7 macrophages
Scientific Reportsvolume, v. 8, (1), December 2018, article number 17412
Gong, Guowei; Wang, Huaiyou; Kong, Xiangpeng; Duan, Ran; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Flavonoids, a Potential New Insight of Leucaena leucocephala Foliage in Ruminant Health
Journal of Agricultural and Food Chemistry, v. 66, (29), July 2018, p. 7616-7626
Xu, Yingchao; Tao, Zhenru; Jin, Yu; Yuan, Yunfei; Dong, Ting Xia; Tsim, Karl Wah Keung; Zhou, Zhongyu Article
Genistein, a Phytoestrogen in Soybean, Induces the Expression of Acetylcholinesterase via G Protein-coupled Receptor 30 in PC12 Cells
Frontiers in Molecular Neuroscience, v. 11, February 2018, article number 59
Liu, Yunle; Xu, Miranda L.; Jin, Yan; Wu, Qiyun; Dong, Tina T. X.; Tsim, Karl Wah Keung Article
Ginseng extracts modulate mitochondrial bioenergetics of live cardiomyoblasts: a functional comparison of different extraction solvents
Journal of Ginseng Research, v. 43, (4), October 2019, p. 517-526
Huang, Yun; Kwan, Kin Leung; Leung, Ka Wing; Yao, Ping; Wang, Huaiyou; Dong, Tingxia; Tsim, Karl Wah Keung Article
Jasmonate-Elicited Stress Induces Metabolic Change in the Leaves of Leucaena leucocephala
Molecules, v. 23, (2), January 2018, article number 188
Xu, Yingchao; Tao, Zhenru; Jin, Yu; Chen, Shuangyan; Zhou, Zhongyu; Gong, Guowei; Yuan, Yunfei; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Microphthalmia-associated transcription factor up-regulates acetylcholinesterase expression during melanogenesis of murine melanoma cells.
The Journal of Biological Chemistry, v. 293, (37), 2018, p. 14417-14428
Wu, Qiyun; Fung, Hei Yiu; Xu, Li; Poon, Ka Man; Liu, Yunle; Kong, Xiang Peng; Yao, Ping; Xiong, Q.P.; Dong, Tingxia; Tsim, Karl Wah Keung Article
Origin of Red Color in Edible Bird's Nests Directed by the Binding of Fe Ions to Acidic Mammalian Chitinase-like Protein
Journal of Agricultural and Food Chemistry, v. 66, (22), June 2018, p. 5644-5653
Wong, Chun Fai; Chan, Kar Lun Gallant; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Prenylated Flavonoids from Roots of Glycyrrhiza uralensis Induce Differentiation of B16-F10 Melanoma Cells
International Journal of Molecular Sciences, v. 19, (8), 16 August 2018, article number 2422
Zheng, Yunfeng; Wang, Huaiyou; Yang, Min; Peng, Guoping; Dong, Tingxia; Xu, Li; Tsim, Karl Wah Keung Article
Quercetin Potentiates the NGF-Induced Effects in Cultured PC 12 Cells: Identification by HerboChips Showing a Binding with NGF
Evidence-based Complementary and Alternative Medicine, v. 2018, 2018, article number 1502457
Chan, Kar Lun Gallant; Hu, Weihui; Zheng, Xuan; Huang, M.; Lin, Xuyan; Wang, Yang; Gong, Guowei; Yang, X. Y.; Tsim, Karl Wah Keung; Dong, Tingxia Article
Searching for Active Ingredients in Edible Bird’s Nest
Journal of Complementory Medicine and Alternative Healthcare, v. 6, (2), May 2018, p. 1-5
Chan, Kar Lun Gallant; Wu, Kevin Q.Y.; Fung, Aster H.Y.; Poon, Karmen K M.; Wang, Caroline Y.W.; Gridneva, Elizaveta; Huang, Rena R.H.; Fung, Sisley Y.Z.; Xia, Y.T.; Hu, Winnie W.H.; Wong, Chun Fai Zack; Tsim, Karl Wah Keung Article
Surveillance of Drug Abuse in Hong Kong by Hair Analysis Using LC-MS/MS
Drug Testing and Analysis, v. 10, (6), June 2018, p. 977-983
Leung, Ka Wing; Wong, Chun Fai; Ho, Yuen Man; Yip, Wan Suet; Cheung, Ka Hei; Ho, Ka Lam Karen; Duan, Ran; Tsim, Karl Wah Keung Article
The Extract of Polygoni Cuspidati Rhizoma et Radix Suppresses the Vascularendothelial Growth Factor-induced Angiogenesis
Phytomedicine, v. 42, March 2018, p. 135-143
Hu, Wei Hui; Chan, Kar-Lun Gallant; Lou, Jian-Shu; Wu, Qi-Yun; Wang, Huai-You; Duan, Ran; Cheng, Michael Yu-Tung; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung Article
The extracts and major compounds derived from astragali radix alter mitochondrial bioenergetics in cultured cardiomyocytes: Comparison of various polar solvents and compounds
International Journal of Molecular Sciences, v. 19, (6), January 2018, article number 1574
Huang, Yun; Kwan, Kin Leung; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiang Peng; Dong, Ting Xia; Tsim, Karl Wah Keung Article
The WT1/MVP-mediated stabilization on mTOR/AKT Axis enhances the effects of cisplatin in non-small cell lung cancer by a reformulated Yu Ping Feng San herbal preparation
Frontiers in Pharmacology, v. 9, (AUG), August 2018, article number 853
Lou, Jianshu; Xia, Yiteng; Wang, Huaiyou; Kong, Xiangpeng; Yao, Ping; Dong, Tingxia; Zhou, Zhongyu; Tsim, Karl Wah Keung Article
The Yin-Yang Property of Chinese Medicinal Herbs Relates to Chemical Composition but Not Anti-Oxidative Activity: An Illustration Using Spleen-Meridian Herbs
Frontiers in Pharmacology, v. 9, November 2018, article number 1304
Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiang Peng; Wang, Long; Dong, Ting Xia; Chen, Yicun; Tsim, Karl Wah Keung Article
健妇胶囊对雌激素、孕激素和促红细胞生成素水平的影响
中药新药与临床药理=Traditional Chinese Drug Research and Clinical Pharmacology, v. 2018, (4), 2018, p. 428-432
董婷霞; 姚娉; 宫帼唯; 詹华强 Article
Acetylcholinesterase regulates inflammatory responses in cultured macrophages: a player in cholinergic anti-inflammatory pathway
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Liu, Yunle; Xu, Li; Kong, Xiang P; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Alkaloids derived from traditional Chinese medicine are inhibitors for inflammation and acetylcholinesterase
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Kong, Xiang Peng; Xu, Li; Liu, Yunle; Wu, Qiyun; Dong, Tingxia; Wan, David CC; Tsim, Karl Wah Keung Conference paper
Applications of edible bird’s nest (EBN) in cosmetics development
10th International Conference on Skin Ageing and Challenges, Portugal, 25-27 February 2018
Chan, Kar Lun Gallant; Wong, Chun Fai; Wu, Qiyun; Fung, Hei Yiu; Poon, Ka Man; Gridneva, Elizaveta; Xia, Yiteng; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Assembly of PRiMA-linked form of acetylcholinesterase in neurons: the role of enzyme inhibitor acting as chemical chaperon
13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Tsim, Karl Wah Keung; Liu, Yunle; Xu, Li; Kong, Xiang P; Wu, Qiyun; Duan, Ran; Dong, Tingxia Conference paper
Comparison of the thermoregulatory effects of spleen-meridian herbs with different herbal properties on yeast induced animal model
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huai-you; Kong, Xiang-Peng; Dong, Tingxia; Chen, Yi-Cun; Tsim, Karl Wah Keung Conference paper
Compatibility study of Danggui Buxue Tang and its chemical ingredients, a simple Chinese herbal decoction prepared from Astragali Radix and Angelicae Sinensis Radix, triggers the expression of neurotropic erythropoietin in cultured NTERA-2 neuron cell model
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Kwan, Kin Leung; Liang, Yanting; Fung, Yun Zhen; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Corylin induced the differentiation, mineralization and metabolic activity in rat osteoblasts and micromass cultures
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Yu, Xiaodan; Xu, Li; Yao, Ping; Dai, Kun; Dong, Tingxia; Ko, Kam Ming; Tsim, Karl Wah Keung Conference paper
Danggui Buxue Tang, an ancient Chinese herbal decoction, protects β-amyloid-induced cell death in cultured cortical neurons
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Gong, Guowei; Dai, Kun; Duan, Ran; Dong, Tingxia; Wang, Huai-You; Tsim, Karl Wah Keung Conference paper
Evidence-based Advanced Personalized Skincare Treatment of SGC Technology with Regeneration, Whitening and Antiageing Properties
The 10th International Conference on Skin Ageing and Challenges, Portugal, 25-27 February 2018
Fung, Hei Yiu; Poon, Ka Man; Chan, Kar Lun Gallant; Wu, Qiyun; Dong, Tingxia; Tsoi, Wai Ki Vickie; Tsoi, Venice; Tsim, Karl Wah Keung Conference paper
Generation of digested products from edible bird’s nest (EBN): development of products for skin whitening
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Chan, Kar Lun Gallant; Wu, Qiyun; Poon, Ka Man; Xiong, Qing-Ping; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Genistein, a phytoestrogen in soybean, induces the expression of acetylcholinesterase via G protein-coupled receptor 30 in PC12 cells
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 09-14 September 2018
Liu, Yunle; Xu, Li; Wu, Qiyun; Dong, Tingxia; Chen, Sibao; Tsim, Karl Wah Keung Conference paper
Indication of vascular endothelial growth factor (VEGF) binding components from extracts of Ginkgo Folium by Herbochips: a platform for drug screening on a chip
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Hu, Weihui; Wang, Huai-You; Duan, Ran; Xiong, Qing-Ping; Xia, Yi-Teng; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Isoorientin derived from Gentiana veitchiorum flower inhibits melanogenesis through down-regulating the expression of microphthalmia-associated transcription factor and tyrosinase
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Wu, Qiyun; Chan, Kar Lun Gallant; Dai, Kun; Kong, Xiang-Peng; Wang, Huai-You; Chen, Yi-Cun; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Isoorientin deriving from Gentiana veitchiorum flower inhibits melanogenesis through down-regulating the expression of microphthalmia-associated transcription factor and tyrosinase
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Wu, Qiyun; Chan, Kar Lun Gallant; Fung, Hei Yiu; Kong, Xiang-Peng; Wang, Huaiyou; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Microphthalmia-associated transcription factor regulates acetylcholinesterase expression during melanogenesis of B16F10 cells: a cholinergic regulator in pigmentation
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Wu, Qiyun; Fung, Hei Yiu; Xu, Li; Liu, Yunle; Duan, Ran; Yao, Ping; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Phytoestrogen induces the expression of acetylcholinesterase via G protein-coupled receptor 30 in cultured PC12 cells
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Liu, Yunle; Xu, Li; Kong, Xiang-Peng; Dai, Kun; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Polydatin suppresses the vascular endothelial growth factor (VEGF)-induced angiogenesis through binding with VEGF and inhibiting its receptor signaling
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Hu, Weihui; Wang, Huaiyou; Kong, Xiang-Peng; Duan, Ran; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Regulation of Acetlcholinesterase via a cAMP-Dependent Pathway During Melanogenesis in Human Skin Cell
10th International Conference on Skin Ageing and Challenges, Portugal, 25-27 February 2018
Wu, Qiyun; Chan, Kar Lun Gallant; Fung, Hei Yiu; Poon, Ka Man; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Stimulatory effects of corylin on differentiation, mineralization and metabolic activity in rat osteoblasts and micromass cultures
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Yu, Xiaodan; Xu, Li; Yao, Ping; Dong, Tingxia; Ko, Kam Ming; Tsim, Karl Wah Keung Conference paper
Study on the correlation between “Yin-Yang” nature of spleen-meridian herbs with the chemical composition, antioxidant activity and effects to energy metabolism
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiang-Peng; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
The antibacterial effects of non-medicinal part of Scutellaria baicalnsis and potential application as an additive in aquaculture feedings
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, 16-17 August 2018
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Kong, Xiang-peng; Tsim, Karl Wah Keung Conference paper
The antibacterial effects of non-medicinal part of Scutellaria baicalnsis and potential application as an additive in aquaculture feedings
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huai-You; Duan, Ran; Dong, Tingxia; Kong, Xiang-Peng; Tsim, Karl Wah Keung Conference paper
Wnt3a induces the transcription of acetylcholinesterase: an enzyme playing a role in osteoblastic differentiation
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Xu, Li; Liu, Yunle; Wu, Qiyun; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
2017 18
A modified Chinese herbal decoction (Kai-Xin-San) promotes NGF-induced neuronal differentiation in PC12 cells via up-regulating Trk A signaling
Frontiers in Cell and Developmental Biology, v. 5, (DEC), December 2017, article number 118
Yan, Lu; Wei, Min; Gong, Amy Guo-wei; Song, Pingping; Lou, Jianshu; Bi, Wenchuan; Xu, Li; Xiong, Aizhen; Dong, Ting Xia; Tsim, Karl Wah Keung Article
A Novel Combination of Four Flavonoids Derived from Astragali Radix Relieves the Symptoms of Cyclophosphamide-Induced Anemic Rats
FEBS Open Bio, v. 7, (3), 1 March 2017, p. 318-323
Zhang, Li Wendy; Gong, Guo-wei; Riaz, Kashif; Deng, Jun Y.; Ho, Chih M.; Lin, Huangquan; Dong, Ting Xia; Lee, Yi-Kuen; Tsim, Karl Wah Keung Article
A Review of Dietary Ziziphus Jujuba Fruit (Jujube): Developing Health Food Supplements for Brain Protection
Evidence - Based Complementary and Alternative Medicine, v. 2017, 2017, Article number 3019568
Chen, Jianping; Liu, Xiaoyan; Li, Zhonggui; Qi, Airong; Yao, Ping; Zhou, Zhongyu; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Asarone from Acori Tatarinowii Rhizome prevents oxidative stress-induced cell injury in cultured astrocytes: A signaling triggered by Akt activation
PLoS ONE, v. 12, (6), June 2017, article number 0179077
Lam, Kelly Yin Ching; Yao, Ping; Wang, Huaiyou; Duan, Ran; Dong, Tina T. X.; Tsim, Karl W. K. Article
Cancer Treatment by Using Traditional Chinese Medicine: Probing Active Compounds in Anti-multidrug Resistance During Drug Therapy
Current Medicinal Chemistry, v. 25, (38), 2018, p. 5128-5141
Lou, Jianshu; Yao, Ping; Tsim, Karl Wah Keung Article
Chemical Differentiation of Dendrobium officinale and Dendrobium devonianum by Using HPLC Fingerprints, HPLC-ESI-MS, and HPTLC Analyses
Evidence-Based Complementary and Alternative Medicine, v. 2017, 2017, article number 8647212
Ye, Zi; Dai, Jia-Rong; Zhang, Cheng-Gang; Lu, Ye; Wu, Lei-Lei; Gong, Amy Guo-wei; Xu, Hong; Tsim, Karl Wah Keung; Wang, Zheng-Tao Article
Comparative Study of Different Acorus Species in Potentiating Neuronal Differentiation in Cultured PC12 Cells
PHYTOTHERAPY RESEARCH, v.31, (11), November 2017, p. 1757-1764
Lam, Yin Ching; Huang, Yun; Yao, Ping; Wang, Huai You; Dong, Ting Xia; Zhou, Zhongyu; Tsim, Karl W. K. Article
Danggui Buxue Tang (Astragali Radix and Angelicae Sinensis Radix) for menopausal symptoms: A review.
Journal of Ethnopharmacology, v. 199, March 2017, p. 205-210
Lin, Huang Quan; Gong, Amy Guo-wei; Wang, Huaiyou; Duan, Ran; Dong, Ting Xia; Zhao, Kui Jun; Tsim, Karl Wah Keung Article
Danggui Buxue Tang, a Simple Chinese Formula Containing Astragali Radix and Angelicae Sinensis Radix, Stimulates the Expressions of Neurotrophic Factors in Cultured Sh-sy5y Cells
Chinese Medicine, v. 12, (24), August 2017, article number 24
Gong, Amy Guo-wei; Wang, Huai You; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Zheng, Y. Z. Article
Ginkgetin Induces Autophagic Cell Death Through p62/SQSTM1- Mediated Autolysosome Formation and Redox Setting in Nonsmall Cell Lung Cancer
Oncotarget, v. 8, (54), October 2017, p. 93131-93148
Lou, Jianshu; Bi, Wenchuan; Chan, Kar Lun Gallant; Jin, Yan; Wong, Chau Wing; Zhou, Zhongyu; Wang, Huai You; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Identification of chemical constituents of Ophiopogon japonicus in Shenmai Injection
Chinese Traditional Patent Medicine, v. 2017, 11, 2017, p. 2340-2344
Li, Ning; Huang, Xing; Zhang, Jia-yu; Wang, Huaiyou; Dong, Tingxia; Tsim, Karl Wah Keung; Tu, Pengfei Article
Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway
Cellular and Molecular Neurobiology, v. 37, (4), May 2017, p. 655-664
Yu, Jie; Zheng, Jiacheng; Lin, Jiajia; Jin, Linlu; Yu, Rui; Mak, Shinghung; Hu, Shengquan; Sun, Hongya; Wu, Xiang; Zhang, Zaijun; Lee, Mingyuen; Tsim, Karl Wah Keung; Su, Wei; Zhou, Wenhua; Cui, Wei; Han, Yifan; Wang, Qinwen Article
Kai-Xin-San Series Formulae Alleviate Depressive-like Behaviors on Chronic Mild Stressed Mice via Regulating Neurotrophic Factor System on Hippocampus
Scientific Reports, v. 7, (1), December 2017, article number 1467
Zhu, Yue; Chao, Cheng; Duan, Xiuzhu; Cheng, Xiaoxuan; Liu, Pei; Su, Shulan; Duan, Jinao; Dong, Tina Tingxia; Tsim, Karl Wah-Keung Article
Polysaccharide of Danggui Buxue Tang, an Ancient Chinese Herbal Decoction, Induces Expression of Pro-inflammatory Cytokines Possibly Via Activation of NFκB Signaling in Cultured RAW 264.7 Cells
Phytotherapy Research, v. 31, (2), February 2017, p. 274-283
Gong, Amy Guo-Wei; Zhang, Minglu; Lam, Ting Wai; Xu, Miranda Li; Wang, Huai You; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Wnt3a Induces the Expression of Acetylcholinesterase during Osteoblast Differentiation via the Runx2 Transcription Factor
Journal of Biological Chemistry, v. 292, (30), Jun 2017, p. 12667-12678
Xu, Miranda Li; Bi, Wenchuan; Liu, Yunle; Dong, Ting Xia; Tsim, Karl Wah Keung Article
参麦注射液中麦冬化学成分的鉴定
中成药=Chinese Traditional Patent Medicine, v. 39, (11), 2017, p. 2340-2344
李宁; 黄星; 王冰; 张加余; 王怀友; 董婷霞; 詹华强; 屠鹏飞 Article
Acetylcholinesterase knock-out mice develop osteoporosis: a role of the globular form enzyme in osteoblastic differentiation
Journal of Neurochemistry, v. 142, (Supplement S2), August 2017, p. 204-204, Special issue on Cholinergic Mechanisms, Guest Editor: Israel Silman, Associate Guest Editors: Pascale Marchot and Marco Prado
Tsim, Karl Wah Keung; Bi, Wenchuan; Xu, Miranda Li; Liu, Yunle; Dong, Tingxia Conference paper
Flavonoids induce the expression of acetylcholinesterase in cultured osteoblasts
Journal of Neurochemistry, v. 142, (Supplement S2), August 2017, p. 207-207, Special issue on Cholinergic Mechanisms, Guest Editor: Israel Silman, Associate Guest Editors: Pascale Marchot and Marco Prado
Bi, Wenchuan; Xu, Li; Liu, Yunle; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
2016 37
2,3,7,8-Tetrachlorodibenzo-P-Dioxin Suppress AChE Activity in NGF Treated PC12 Cells
Chemico-Biological Interactions, v. 259, November 2016, p. 282-285
Xu, Li; Chen, Yangsheng; Xie, Heidi Qun Hui; Xu, Tuan; Fu, Hualing; Zhang, Songyan; Tsim, Karl Wah Keung; Bi, Wenchuan; Zhao, Bin Article
A Chinese Herbal Decoction, Reformulated from Kai-Xin-San, Relieves the Depression-like Symptoms in Stressed Rats and Induces Neurogenesis in Cultured Neurons
Scientific Reports, v. 6, July 2016, article number 30014
Yan, Lu; Hu, Qinghua; Mak, Marvin S.H.; Lou, Jianshu; Xu, Li; Bi, Wenchuan; Zhu, Yue; Wang, Huai You; Dong, Ting Xia; Tsim, Karl Wah Keung Article
A High Throughput Screening Platform for Skin Tuning Properties from Natural Products: Identification of Skin Tanning Compounds
Journal of Cosmetics, Dermatological Sciences and Applications, v. 6, (5), December 2016, p. 199-209
Chan, Kar Lun Gallant; Wu, Qiyun; Wong, Chun Fai; Fung, Hei Yiu; Lin, Xuyan; Lou, Jianshu; Dong, Tingxia; Tsim, Karl Wah Keung Article
Anxiety and Depression with Neurogenesis Defects in Exchange Protein Directly Activated by cAMP 2-Deficient Mice are Ameliorated by a Selective Serotonin Reuptake Inhibitor, Prozac
Translational Psychiatry, v. 6, (9), September 2016, article number e881
Zhou, L.; Ma, Sukling; Yeung, Patrick Ka Kit; Wong, Yung Hou; Tsim, Karl Wah Keung; So, K. F.; Lam, L.C.W.; Chung, S.K. Article
Asarone from Acori Tatarinowii Rhizoma Potentiates the Nerve Growth Factor-Induced Neuronal Differentiation in Cultured PC12 Cells: A Signaling Mediated by Protein Kinase A
PLoS ONE, v. 11, (9), September 2016, article number e0163337
Lam, Yin Ching; Chen, Jianping; Lam, Ting Wai; Wu, Qiyun; Yao, Ping; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung Article
Authentication of Acori Tatarinowii Rhizoma (Shi Chang Pu) and its Adulterants by Morphological Distinction, Chemical Composition and ITS Sequencing
Chinese Medicine, v. 11, (1), September 2016, Article number 41
Lam, Yin Ching; Ku, Chuen Fai; Wang, Huai You; Chan, Kar Lun Gallant; Yao, Ping; Lin, Huang Quan; Dong, Ting Xia; Zhang, Hong Jie; Tsim, Karl Wah Keung Article
Badiranji Buya Keli, a Traditional Uyghur Medicine, Induces Vasodilation in Rat Artery: Signaling Mediated by Nitric Oxide Production in Endothelial Cells
Phytotherapy Research, v. 30, (1), January 2016, p. 16-24
Miernisha, Abudureyimu; Bi, Wenchuan; Cheng, Kwan Wai; Xing, J.G.; Liu, Jian; Maiwulanjiang, Maitinuer; Aisa, Haji Akber Kber; Dong, Ting Xia; Lin, Huangquan; Huang, Y.; Tsim, Karl Wah Keung Article
Chemical and biological assessment of Jujube (Ziziphus jujuba)-containing herbal decoctions: Induction of erythropoietin expression in cultures
Journal of Chromatography B, v. 1026, July 2016, p. 254-262
Lam, Ting Wai; Chan, Pui Hei; Lee, Pinky Sum-chi; Lau, Kei Man; Kong, Yeung Yeung Ava; Gong, Amy Guo-wei; Xu, Miranda Li; Lam, Yin Ching; Dong, Tingxia; Lin, Huangquan; Tsim, Karl Wah Keung Article
Clivorine, an Otonecine Pyrrolizidine Alkaloid from Ligularia Species, Impairs Neuronal Differentiation via NGF-Induced Signaling Pathway in Cultured PC12 Cells
Phytomedicine, v. 23, (9), August 2016, p. 931-938
Xiong, Aizhen; Yan, Artemis Lu; Bi, Wenchuan; Lam, Yin Ching; Chan, Kar Lun Gallant; Lau, Kei May; Dong, Ting Xia; Lin, Huangquan; Yang, Li; Wang, Zhengtao; Tsim, Karl Wah Keung Article
Danggui Buxue Tang, a Chinese Herbal Decoction, Induces Nitric Oxide Production in Cultured Endothelial Cells: Probing Calycosin as a Key Player by Chemical Knock-out Approach
Journal of Research and Development, March 2016, S1:1
Gong, Guowei; Lam, Ting Wai; Zhang, Minglu; Deng, Junyang; Wang, Huaiyou; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung Article
Danggui Buxue Tang, Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, Induces Production of Nitric Oxide in Endothelial Cells: Signaling Mediated by Phosphorylation of ndothelial Nitric Oxide Synthase
Planta medica, v. 82, (5), March 2016, p. 418-423
Gong, Amy Guowei; Lau, Keiman; Zhang, Minglu; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Determination of hair ketamine cut-off value from Hong Kong ketamine users by LC-MS/MS analysis
Forensic Science International, v. 259, February 2016, p. 53-58
Leung, Ka Wing; Wong, Zack C.F.; Ho, Janet Y.M.; Yip, Ada W.S.; Ng, Jenny S.C.; Ip, Stanley P.H.; Ng, Winki Y.Y.; Ho, Karen K.L.; Duan, Ran; Zhu, Kevin Y.; Tsim, Karl Wah Keung Article
Expression of Globular form Acetylcholinesterase is not Altered in P2Y1R Knock-Out Mouse Brain
Chemico-Biological Interactions, v. 259, November 2016, p. 291-294
Cui, Di; Xu, Miranda Li; Liu, Yunle; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung; Bi, Wenchuan Article
Extract of Ziziphus jujuba Fruit (Jujube) Stimulates Expression of Enzymes Responsible for Heme Recycle via Anti-oxidant Response Element in Cultured Murine Macrophages
Phytotherapy Research, v. 30, (2), February 2016, p. 267-271
Chen, Jianping; Lam, Candy T.W.; Li, Zhonggui; Yao, Ping; Lin, Huangquan; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Ferulic Acid Orchestrates Anti-oxidation Properties of Danggui Buxue Tang, an Ancient Herbal Decoction: Elucidation by Chemical Knock-out Approach
PLoS ONE, v. 11, (11), November 2016, Article number e0165486
Gong, Amy Guo-wei; Huang, Yun; Wang, Huai You; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Indication of Nerve Growth Factor Binding Components from Herbal Extracts by HerboChip: A Platform for Drug Screening on a Chip
Chinese Medicine, v. 11, (1), July 2016, article number 34
Lee, Pinky Sum-chi; Zhang, Minglu; Yan, Lu; Lam, Yin Ching; Dong, Ting Xia; Lin, Huangquan; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung Article
Jujube-containing herbal decoctions induce neuronal differentiation and the expression of anti-oxidant enzymes in cultured PC12 cells
Journal of Ethnopharmacology, v. 188, July 2016, p. 275-283
Lam, Ting Wai; Gong, Amy Guo-wei; Lam, Yin Ching; Zhang, Laura M.; Chen, Jian-Ping; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung Article
Kai-Xin-San, a Standardized Traditional Chinese Medicine Formula, Up-Regulates the Expressions of Synaptic Proteins on Hippocampus of Chronic Mild Stress Induced Depressive Rats and Primary Cultured Rat Hippocampal Neuron
Journal of Ethnopharmacology, v. 193, December 2016, p. 423-432
Zhu, Yue; Duan, Xiuzhu; Cheng, Xiaoxuan; Cheng, Xiaonan; Li, Xu; Zhang, Liu; Liu, Pei; Su, Shulan; Duan, Jinao; Dong, Ting Xia; Tsim, Karl Wah Keung; Huang, Fei Article
Kai-Xin-San, a Traditional Chinese Medicine Formula, Induces Neuronal Differentiation of Cultured PC12 Cells: Modulating Neurotransmitter Regulation Enzymes and Potentiating NGF Inducing Neurite Outgrowth
Journal of Ethnopharmacology, v. 193, December 2016, p. 272-282
Zhu, Yue; Duan, Xiuzhu; Huang, Feiyu; Cheng, Xiaonan; Zhang, Liu; Liu, Pei; Shulan, Su; Duan, Jinao; Dong, Tinatingxia; Tsim, Karl Wah Keung Article
Neuroprotection Against Glutamate-Induced Excitotoxicity and Induction of Neurite Outgrowth by T-006, a Novel Multifunctional Derivative of Tetramethylpyrazine in Neuronal Cell Models
Neurochemistry International, v. 99, October 2016, p. 194-205
Xu, Daping; Chen, Haiyun; Mak, Shinghung; Hu, Shengquan; Tsim, Karl Wah Keung; Hu, Yuanjia; Sun, Yewei; Zhang, Gaoxiao; Wang, Yuqiang; Zhang, Zaijun; Han, Yifan Article
New Perspectives for Multi-Level Regulations of Neuronal Acetylcholinesterase by Dioxins
Chemico-Biological Interactions, v. 259, November 2016, p. 286-290
Xie, Heidi Qun Hui; Xu, Tuan; Chen, Yangsheng; Li, Yunping; Xia, Yingjie; Xu, Sherry Li; Wang, Lingyun; Tsim, Karl Wah Keung; Zhao, Bin Article
Quantitative Analysis of Nucleosides and Nucleobases in Deer Antler: Variation in Different Species
Pharmaceutica Analytica Acta, v. 7, (4), April 2016, article number 1000474
Bi, Dan; Zhang, L.M.L.; Tang, Wai Lun; Duan, Ran; Leung, Ka Wing; Dong, Tingxia; Wong, Yung Hou; Lin, Huangquan; Tsim, Karl Wah Keung Article
The Estrogenic Properties Of Danggui Buxue Tang, A Chinese Herbal Decoction, Are Triggered Predominantly By Calycosin In Mcf-7 Cells
Journal of ethnopharmacology, v. 189, Aug 2016, p. 81-89
Gong, Amy Guo-wei; Lau, Kei Man; Xu, Miranda Li; Lin, Huangquan; Dong, Ting Xia; Zheng, Ken Y.Z.; Zhao, K.J.; Tsim, Karl Wah Keung Article
Transcriptional activity of acetylcholinesterase gene is regulated by DNA methylation during C2C12 myogenesis Transcriptional activity of acetylcholinesterase gene is regulated by DNA methylation during C2C12 myogenesis
Brain research, v. 1642, July 2016, p. 114-123
Lau, Kei Man; Gong, Amy Guowei; Xu, Miranda Li; Lam, Ting Wai; Zhang, Minglu; Bi, Wenchuan; Cui, Di; Cheng, Wai Ming Anthony; Dong, Ting Xia; Tsim, Karl Wah Keung; Lin, Huangquan Article
Yu Ping Feng San Reverses Cisplatin-induced Multi-drug Resistance in Lung Cancer Cells via Regulating Drug Transporters and p62/TRAF6 Signalling
Scientific Reports, v. 6, August 2016, article number 31926
Lou, Jianshu; Yan, Lu; Bi, Wenchuan; Chan, Kar Lun Gallant; Wu, Qiyun; Liu, Yunle; Huang, Yun; Yao, Ping; Du, Crystal Y.Q.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Chemical and Biological Assessment of Ziziphus jujuba (Jujubes) Fruit from China of Different Geographical Sources and Developmental Stages: Chemical Composition and Possible Targets in Developing Health Food Products
Chinese Dates: A Traditional Functional Food / Dongheng Liu, Xingqian Ye, Yueming Jiang, editors. Boca Raton : CRC Press - Taylor & Francis Group, 2016, p. 83-97
Chen, Jianping; Lam, Ting Wai; Li, Zhonggui; Yao, Ping; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung Book chapter
Asarone from Acori Tatarinowii Rhizoma potentiates the nerve growth factor-induced neuronal differentiation in cultured PC12 cells: A signaling mediated by protein kinase A
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 12 August 2016
Lam, Yin Ching; Lin, Huangquan; Dong, Ting Xia; Yao, Ping; Lam, Ting Wai; Tsim, Karl Wah Keung Conference paper
Authentication of Acori Tatarinowii Rhizoma and its adulterants: Morphological distinction, chemical composition and DNA analysis
China Medicinal Materials Resources Conference, Xian, China, August 2016
Tsim, Karl Wah Keung; Lam, Yin Ching; Wang, Huaiyou; Dong, Tingxia Conference paper
Characterisation of spleen-meridian herbs using HPLC and UPLC/Q-TOF-MS ?ngerprints combined with principal component analysis
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, August 12th, 2016
Huang, Yun; Dong, Ting Xia; Yao, Ping; Zhou, Zhongyu; Lin, Huangquan; Tsim, Karl Wah Keung Conference paper
Chemical and biological assessment of Ziziphus jujube fruits from China: different geographical sources and development stages
第五届可食和药用植物资源及功能成分国际学术研讨会, 深圳, 2016年11月4日至11月7日
Tsim, Karl Wah Keung Conference paper
Chemical and biological assessment of Ziziphus jujube fruits from China: different geographical sources and development stages
China Medicinal Materials Resources Conference, Xian, China, 10 August, 2016
Tsim, Karl Wah Keung; Lam, Candy T.W.; Chen, Jianping; Zhou, Zhongyu; Gong, Guowei; Wang, Huaiyou; Yao, Ping; Duan, Ran Conference paper
Erythropoietin (Epo)-induced Signaling is Interfered by Acetylcholinesterase (AChE) in Erythroblasts and Neurons
Journal of Neurochemistry, v. 142, August 2017, p. 214-215
Liu, Yunle; Dong, Ting Xia; Xu, Miranda Li; Bi, Wenchuan; Luk, Wilson K.W.; Tsim, Karl Wah Keung Conference paper
Flavonoids Induce the Expression of Acetylcholinesterase in Cultured Osteoblasts
Chemico-Biological Interactions, v. 259, (B), 25 November 2016, p. 295-300
Xu, Miranda Li; Bi, Wenchuan; Kong, Yeung Yeung Ava; Dong, Ting Xia; Wong, Yung Hou; Tsim, Karl Wah Keung Conference paper
Numerical Simulations of Electrochemical Impedance Spectroscopy of Polymer-based Micro Electrochemical Sensors for Rapid Identification of DNA Molecules from Traditional Chinese Medicine
8th International Symposium on Microchemistry and Microsystems (ISMM 2016), Hong Kong, 30 May-1 June 2016
Gao, Bo; Xu, Wei; Ma, Shenhui; Lee, Yi-Kuen; Tsim, Karl Wah Keung; Dong, Tingxia; Lam, Kelly Y.C.; Zhang, Anping Conference paper
The Content of Arsenic (AS) in Cordyceps Sinensis
China Medicinal Materials Resources Conference, Xian, China, August 2016
Tsim, Karl Wah Keung; Dong, Tingxia; Duan, Ran; Tang, Wai Lun; Lam, Yin Ching Conference paper
The osteogenic properties of Danggui Buxue Tang, a Chinese herbal decoction containing Astragali Radix and Angelicae Sinensis Radix: transcriptomics analysis of specific chemical knock-out herbal decoction
International Conference on DNA Technology for Authentication, Quality Control and Conservation of Herbal Material, The Chinese University of Hong Kong, 12 - 14 December, 2016
Gong, Amy G.W.; Dong, Tina Ting-xia; Tsim, Karl Wah Keung Conference paper
Yu Ping Feng San, a Chinese herbal decoction, reverses cisplatin induced multi-drug resistance in non-small cell lung cancer
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, August 12th, 2016
Lou, Jianshu; Yao, Ping; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung Conference paper
2015 30
Authentication of Cordyceps sinensis by DNA Analyses: Comparison of ITS Sequence Analysis and RAPD-Derived Molecular Markers
Molecules, v. 20, (12), December 2015, p. 22454-22462
Lam, Yin Ching; Chan, Kar Lun Gallant; Xin, Guizhong; Xu, Hong; Ku, Chuen Fai; Chen, Jianping; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Calycosin orchestrates the functions of Danggui Buxue Tang, a Chinese herbal decoction composing of Astragali Radix and Angelica Sinensis Radix: An evaluation by using calycosin-knock out herbal extract
Journal of Ethnopharmacology, v. 168, June 2015, p. 150-157
Gong, Amy Guo-wei; Li, Ning; Lau, Kei Man; Lee, Pinky Sum-chi; Yan, Lu; Xu, Miranda Li; Lam, Ting Wai; Kong, Yeung Yeung Ava; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Edible Bird’s Nest, an Asian Health Food Supplement, Possesses Skin Lightening Activities: Identification of N-Acetylneuraminic Acid as Active Ingredient
Journal of Cosmetics, Dermatological Sciences and Applications, v. 5, (4), November 2015, article number 61507, p. 262-274
Chan, Kar Lun Gallant; Wong, Chun Fai; Lam, Yin Ching; Cheng, Kwan Wai; Zhang, Minglu; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung Article
Evaluation of Hemostatic and Anti-inflammatory Activities of Extracts from Different Lagochilus Species in Experimental Animals: Comparison of Different Extractives and Sources
Phytotherapy Research, v. 29, (1), 2015, p. 22-29
Jiao, Ying; Chen, Pei-Hua; Xiong, Aizhen; Wang, Zheng-Tao; Tsim, Karl Wah Keung; Chou, Gui-Xin; Xu, Hong Article
Fast Simultaneous Determination of 13 Nucleosides and Nucleobases in Cordyceps sinensis by UHPLC-ESI-MS/MS
Molecules, v. 20, (12), December 2015, p. 21816-21825
Zong, Shiyu; Han, Han; Wang, Bing; Li, Ning; Dong, Ting Xia; Zhang, Tong; Tsim, Karl Wah Keung Article
Fruit of Ziziphus jujuba (Jujube) at Two Stages of Maturity: Distinction by Metabolic Profiling and Biological Assessment
Journal of Agricultural and Food Chemistry, v. 63, (2), January 2015, p. 739-744
Chen, Jianping; Chan, Pui Hei; Lam, Candy Ting Wai; Li, Zhonggui; Lam, Kelly Yin Ching; Yao, Ping; Dong, Tina Ting Xia; Lin, Huangquan; Lam, Henry H N; Tsim, Karl Wah Keung Article
Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β
Journal of Molecular Neuroscience, v. 57, (4), December 2015, p. 561-570
Hu, Shengquan; Cui, Wei; Zhang, Zaijun; Mak, Shinghung; Xu, Daping; Li, Gang; Hu, Yuanjia; Wang, Yuqiang; Lee, Mingyuen; Tsim, Karl Wah Keung; Han, Yifan Article
Inhibiting beta-Amyloid-Associated Alzheimer's Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue
Journal of Molecular Neuroscience, v. 55, (4), March 2015, p. 1014-1021
Hu, Shengquan; Wang, Rui; Cui, Wei; Zhang, Zaijun; Mak, Shinghung; Xu, Daping; Choi, Chunglit; Tsim, Karl Wah Keung; Carlier, Paul R.; Lee, Mingyuen; Han, Yifan Article
Optimizing the Compatibility of Paired-Herb in an Ancient Chinese Herbal Decoction Kai-Xin-San in Activating Neurofilament Expression in Cultured PC12 Cells
Journal of Ethnopharmacology, v. 162, March 2015, p. 155-162
Yan, Lu; Xu, Sherry L.; Zhu, Kevin Y.; Lam, Yin Ching; Xin, Guizhong; Maiwulanjiang, Maitinuer; Li, Ning; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung Article
Reduced Expression of P2Y2 Receptor and Acetylcholinesterase at Neuromuscular Junction of P2Y1 Receptor Knock-out Mice
Journal of Molecular Neuroscience, v. 57, (3), November 2015, p. 446-451
Xu, Miranda Li; Bi, Wenchuan; Cheng, Kwan Wai; Mak, Shinghung; Yao, Ping; Luk, Wilson K.W.; Lau, Kei May; Cheng, Anthony W.M.; Tsim, Karl Wah Keung Article
Robust Neuritogenesis-Promoting Activity by Bis(heptyl)-Cognitin Through the Activation of alpha7-Nicotinic Acetylcholine Receptor/ERK Pathway
CNS Neuroscience and Therapeutics, v. 21, (6), June 2015, p. 520-529
Hu, Sheng-Quan; Cui, Wei; Mak, Shing-Hung; Choi, Chung-Lit; Hu, Yuan-Jia; Li, Gang; Tsim, Karl Wah Keung; Pang, Yuan-Ping; Han, Yi-Fan Article
The Volatile Oil of Nardostachyos Radix et Rhizoma Induces Endothelial Nitric Oxide Synthase Activity in HUVEC Cells
PLoS ONE, v. 10, (2), February 2015, article number e0116761
Maiwulanjiang, Maitinuer; Bi, Wenchuan; Lee, Pinky Sum-chi; Xin, Guizhong; Miernisha, Abudureyimu; Lau, Kei May; Xiong, Aizhen; Li, Ning; Dong, Ting Xia; Aisa, Haji Akber Kber; Tsim, Karl Wah Keung Article
The water extract of Angelica Sinensis Radix protects cultured PC12 cells against oxidative stress: suppression of reactive oxygen species and activation of anti-oxidant response elements
Oxidants and Antioxidants in Medical Science, v. 4, (1), 2015, p. 39-48
Lee, Pinky Sum-Chi; Yan, Artemis Lu; Gong, Amy Guo-Wei; Choi, Roy Chi-Yan; Lin, Huang-Quan; Tsim, Karl Wah Keung Article
Three N-Glycosylation Sites of Human Acetylcholinesterase Shares Similar Glycan Composition
Journal of Molecular Neuroscience, v. 57, (4), December 2015, p. 486-491
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Keiman; Bi, Wenchuan; Cheng, Anthony W.M.; Gong, Amy Guo-wei; Lin, Huangquan; Tsim, Karl Wah Keung Article
Yu Ping Feng San, an Ancient Chinese Herbal Decoction, Induces Gene Expression of Anti-viral Proteins and Inhibits Neuraminidase Activity
Phytotherapy Research, v. 29, (5), May 2015, p. 656-661
Du, Crystal Ying Qing; Zheng, Ken Y.Z.; Bi, Wenchuan; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung Article
冬虫夏草中核苷类成分含量测定及HPLC指纹图谱研究
中药材=Journal of Chinese medicinal materials, v. 38, (5), May 2015, p. 952-956
王冰; 李宁; 董婷霞; 詹华强 Article
浸泡和酸性物质促进硫熏山药脱硫的研究
中药材, v. 38, (2), 2015, p. 271-274
郑玉忠; 谢丽玲; 乐智勇; 贺震旦; 詹华强; 曹晖 Article
硫熏山药对六味地黄丸中有效成分的影响
中国实验方剂学杂志=Chinese Journal of Experimental Traditional Medical Formulae, v. 21, (18), September 2015, p. 48-51
郑玉忠; 张振霞; 张勇; 刘亚群; 谢丽玲; 乐智勇; 贺震旦; 詹华强; 曹晖 Article
Chemical And Biological Studies Of Chinese Date Decoctions
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Lam, C.T.W.; Gong, Amy Guo-wei; Lam, K.Y.C.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Comparison Of Different Authentication Methods On Acori Tatarinowii Rhizoma
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Lam, K.Y.C.; Chan, Kar Lun Gallant; Xin, G.Z.; Lam, C.T.W.; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Cross‐talk of acetylcholinesterase with presenilin‐1
12th International Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12th ChE - PON6), Alicante, Spain, 27 September - 2 October 2015
Saez‐valero, Javier; Vidal, Cecilio J.; Campanari, Maria‐Letizia; Garcla‐ayllón, Maria‐Salud; Tsim, Karl Wah Keung Conference paper
Establishment Of Quality Control Standard For Edible Bird's Nest By Monoclonal Antibodies And Fingerprint
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Wong, Z.C.F.; Chan, Kar Lun Gallant; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Expression of P2Y receptor and acetylcholinesterase in muscle and brain of P2Y1 knock-out mice
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Cui, Di; Bi, Wenchuan; Xu, Miranda Li; Lau, Kitty K.m.; Luk, Wilson K.w.; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Functional and Quantitative PTM Proteomics in Study of Ethylene Signaling
11th Cross-straight Plant Biotechnology Symposium, Southern Central China Agricultural University. Wuhan, China, 2015
Li, Ning Conference paper
Low-Cost Portable Polymer-based Micro Electrochemical Sensor (PMES) System for Rapid Detection of the Cordyceps Sinensis
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Chemical and Biological Microsystems Society (CBMS), 2015, p. 1734-1736
Ma, Shenhui; Riaz, Kashif; Maslova, Anastasia; Gao, Bo; Alsuhaimi, Awadh O.; Lam, Yin Ching; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Zhang, Anping; Lee, Yi-Kuen Conference paper
Protective Functions Of Flavonoids In Nervous System Via Epo Regulation
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Zheng, Xuan; Bi, Wenchuan; Yao, Ping; Yan, Lu; Luk, Wilson K.W.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The bone morphogenetic protein 2 (BMP2)-induced downstream signalings are altered by globular form AChE in cultured osteoblasts
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Bi, Wenchuan; Xu, Miranda Li; Lau, Kitty K.M.; Cui, Di; Lin, Huangquan; Ip, Paul S.P.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The Effect of N-glycosylation on the Enzymatic Activity, Stability and Transportation of Acetylcholinesterase
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Kei Man; Bi, Wenchuan; Cui, Di; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The N‐glycosylation of acetylcholinesterase regulates the enzymatic activity, stability and transport in a recombinant expression system
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Kitty K.M.; Bi, Wenchuan; Cui, Di; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Transcriptional regulation of acetylcholinesterase in different cells
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonas, Elche, Spain, 27 September - 2 October 2015
Tsim, Karl Wah Keung; Luk, Wilson K.w.; Bi, Wenchuan; Yao, Ping; Lau, Kitty K.m.; Xu, Miranda Li; Cui, Di; Dong, Ting Xia Conference paper
2014 36
A Chemically Standardized Extract of Ziziphus jujuba Fruit (Jujube) Stimulates Expressions of Neurotrophic Factors and Anti-oxidant Enzymes in Cultured Astrocytes
Phytotherapy Research, v. 28, (11), 2014, p. 1727-1730
Chen, Jianping; Yan, Artemis Lu; Lam, Kelly Yin Ching; Lam, Candy Ting Wai; Li, Ning; Yao, Ping; Xiong, Aizhen; Dong, Tingxia; Tsim, Karl Wah Keung Article
A Standardized Extract of the Fruit of Ziziphus jujuba (Jujube) Induces Neuronal Differentiation of Cultured PC12 Cells: A Signaling Mediated by Protein Kinase A
Journal of Agricultural and Food Chemistry, v.62, (8), 2014, Feb, p. 1890-1897
Chen, Jianping; Maiwulanjiang, Maitinuer; Lam, Yin Ching; Zhang, Wendyli; Zhan, Yaxian; Lam, Ting Wai; Xu, Li; Zhu, Kevin Yue; Yao, Ping; Lau, David Tai Wai; Dong, Tingxia; Tsim, Karl Wah Keung Article
Acetylcholinesterase Protein Level Is Preserved in the Alzheimer's Brain
Journal of Molecular Neuroscience, v. 53, (3), June 2014, p. 446-453
Campanari, Maria-Letizia; Garcia-Ayllon, Maria-Salud; Blazquez-Llorca, Lidia; Luk, Wilson K.W.; Tsim, Karl Wah Keung; Saez-Valero, Javier Article
Alkaloids of Linderae Radix Suppressed the Lipopolysaccharide-induced Expression of Cytokines in Cultured Macrophage RAW 264.7 cells
TANG: Humanitas Medicine, v. 4, (4), 2014
Chou, Jiyao; Lam, Yin Ching; Chen, Jianping; Yao, Ping; Dong, Tingxia; Xiong, Aizhen; Chou, Guixin; Wang, Zhengtao; Tsim, Karl Wah Keung Article
An application of target profiling analyses in the hepatotoxicity assessment of herbal medicines: comparative characteristic fingerprint and bile acid profiling of Senecio vulgaris L. and Senecio scandens Buch.-Ham
Analytical and Bioanalytical Chemistry, v. 406, (29), November 2014, p. 7715-7727
Xiong, Aizhen; Fang, Lianxiang; Yang, Xiao; Yang, Fan; Qi, Meng; Kang, Hong; Yang, Li; Tsim, Karl Wah Keung; Wang, Zhengtao Article
Characterizations of Cholinesterases in Golden Apple Snail (Pomacea canaliculata)
Journal of Molecular Neuroscience, v. 53, (3), 2014, p. 424-428
Zou, Xiang-Hui; Xie, Heidi Qun-Hui; Zha, Guang-Cai; Chen, Vicky Ping; Sun, Yan-Jie; Zheng, Yu-Zhong; Tsim, Karl Wah Keung; Dong, Tina Ting-Xia; Choi, Roy Chi-Yan; Luk, Wilson Kin-Wai Article
Ferulic acid enhances the chemical and biological properties of Astragali Radix: A stimulator for danggui buxue tang, an ancient chinese herbal decoction
Planta Medica, v. 80, (2-3), February 2014, p. 159-164
Zheng, Ken Yu Zhong; Zhang, Zhenxia; Du, Crystal Ying Qing; Zhang, Wendyli; Bi, Cathy Wen Chuan; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Functions of Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, in Uterus and Liver are Both Estrogen Receptor-Dependent and -Independent
Evidence-based Complementary and Alternative Medicine, v. 2014, 2014, article number 438531
Zierau, Oliver; Zheng, Ken Yuzhong; Papke, Anja; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Vollmer, Guenter Article
Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture
Evidence-based Complementary and Alternative Medicine, v. 2014, 2014, article number 608721
Zhang, Wendy Li; Chen, Jian-Ping; Lam, Kelly Yin-Ching; Zhan, Janis Ya-Xian; Yao, Ping; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung Article
Identification of Angelica oil as a suppressor for the biological properties of Danggui Buxue tang: A Chinese herbal decoction composes of Astragali Radix and Angelica Sinensis Radix
Journal of Ethnopharmacology, v. 154, (3), July 2014, p. 825-831
Zhan, Janis Ya-xian; Zheng, Ken Yu-zhong; Zhang, Wendy Li; Chen, Jian-ping; Yao, Ping; Bi, Cathy Wen-chuan; Dong, Tina Ting-xia; Tsim, Karl Wah Keung Article
Metabolomic and Genomic Evidence for Compromised Bile Acid Homeostasis by Senecionine, a Hepatotoxic Pyrrolizidine Alkaloid
Chemical Research in Toxicology, v. 27, (5), May 2014, p. 775-786
Xiong, Aizhen; Yang, Fan; Fang, Lianxiang; Yang, Li; He, Yuqi; Wan, Yvonne Yu-Jui; Xu, Ying; Qi, Meng; Wang, Xiuli; Yu, Kate; Tsim, Karl Wah Keung; Wang, Zhengtao Article
Metabonomic Analysis of Water Extracts from Different Angelica Roots by 1H-Nuclear Magnetic Resonance Spectroscopy
Molecules, v. 19, (3), 2014, p. 3460-3470
Chan, Pui Hei Nicholas; Zhang, Wendy L.; Lau, Chungho; Cheung, Chi Yuen; Keun, Hector C.; Tsim, Karl Wah Keung; Lam, Henry H N Article
Presenilin-1 Influences Processing of the Acetylcholinesterase Membrane Ancho PRiMA
Neurobiology of Aging, v. 35, (7), July 2014, p. 1526-1536
Garcia-Ayllon, Maria-Salud; Campanari, Maria-Letizia; Montenegro, Maria-Fernanda; Cuchillo-Ibanez, Inmaculada; Belbin, Olivia; Lleo, Alberto; Tsim, Karl Wah Keung; Vidal, Cecilio J.; Saez-Valero, Javier Article
Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by 1H-NMR Metabolic Profiling
Evidence-Based Complementary and Alternative Medicine, v. 2014, 2014, article number 567893
Chan, Pui Hei; Zhang, Wendy L.; Cheung, Chi Yuen; Tsim, Karl W.K.; Lam, Henry Article
Quantification of the Transcripts Encoding Different Forms of AChE in Various Cell Types: Real-Time PCR Coupled with Standards in Revealing the Copy Number
Journal of Molecular Neuroscience, v. 53, (3), July 2014, p. 461-468
Bi, Wenchuan; Luk, Wilson K.W.; Campanari, Maria-Letizia; Liu, Yuen H.; Xu, Li; Lau, Kei May; Xu, Miranda Li; Choi, Chi Yan; Saez-valero, Javier; Tsim, Karl Wah Keung Article
Rapid identification of plant materials by wooden-tip electrospray ionization mass spectrometry and a strategy to differentiate the bulbs of Fritillaria
Analytica Chimica Acta, v. 820, April 2014, p. 84-91
Xin, Guizhong; Hu, Bin; Shi, Zi Qi; Lam, Yin Ching; Dong, Ting Xia; Li, Ping; Yao, Zhong Ping; Tsim, Karl Wah Keung Article
Sunitinib Produces Neuroprotective Effect Via Inhibiting Nitric Oxide Overproduction
CNS Neuroscience and Therapeutics, v. 20, (3), March 2014, p. 244-252
Cui, Wei; Zhang, Zai-Jun; Hu, Sheng-Quan; Mak, Shing-Hung; Xu, Da-Ping; Choi, Chung-Lit; Wang, Yu-Qiang; Tsim, Karl Wah Keung; Lee, Ming-Yuen; Rong, Jian-Hui; Han, Yi-Fan Article
Synergistic Inhibition on Acetylcholinesterase by the Combination of Berberine and Palmatine Originally Isolated from Chinese Medicinal Herbs
Journal of Molecular Neuroscience, v. 53, (3), 2014, p. 511-516
Mak, Shinghung; Luk, Wilson W.K.; Cui, Wei; Hu, Shengquan; Tsim, Karl Wah Keung; Han, Yifan Article
The Extract of Ziziphus jujuba Fruit (Jujube) Induces Expression of Erythropoietin Via Hypoxia-Inducible Factor-1α in Cultured Hep3B Cells
Planta Medica, v. 80, (17), September 2014, p. 1622-1627
Chen, Jianping; Lam, Ting Wai; Kong, Yeung Yeung Ava; Zhang, Li Wendy; Zhan, Yaxian; Bi, Wenchuan; Chan, Kar Lun Gallant; Lam, Yin Ching; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Article
The Standardized Extract of Ziziphus jujuba Fruit (Jujube) Regulates Pro-inflammatory Cytokine Expression in Cultured Murine Macrophages: Suppression of Lipopolysaccharide-stimulated NF-kappa B Activity
Phytotherapy research : PTR, v. 28, (10), October 2014, p. 1527-1532
Chen, Jianping; Du, Crystal Yingqing; Lam, Kelly Yin Ching; Zhang, Wendy L.; Lam, Candy Ting Wai; Yan, Artemis Lu; Yao, Ping; Lau, David Tai Wai; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The sulfur-fumigation reduces chemical composition and biological properties of Angelicae sinensis radix
Phytomedicine, v. 21, (11), September 2014, p. 1318-1324
Zhan, Janis Ya-Xian; Yao, Ping; Bi, Cathy Wen-Chuan; Zheng, Ken Yu-zhong; Zhang, Wendy Li; Chen, Jian-Ping; Dong, Tina Ting-Xia; Su, Zi-Ren; Tsim, Karl Wah Keung Article
The volatile oil of Nardostachyos Radix et Rhizoma inhibits the oxidative stress-induced cell injury via reactive oxygen species scavenging and Akt activation in H9c2 cardiomyocyte
Journal of Ethnopharmacology, v. 153, (2), April 2014, p. 491-498
Maiwulanjiang, Maitinuer; Chen, Jianping; Xin, Guizhong; Gong, Amy G.W.; Miernisha, Abudureyimu; Du, Crystal Y.Q.; Lau, Keiman; Lee, Pinky S.C.; Chen, Jihang; Dong, Tina T.X.; Aisa, Haji A.; Tsim, Karl Wah Keung Article
UPLC-MS/MS法测定吸毒者头发中10种毒品代谢物的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 34, (3), 2014, p. 516-522
谢普; 王铁杰; 殷果; 闫研; 丁振浩; 肖丽和; 詹华强; 梁嘉荣; 李璐; 孙新珺; 毕开顺 Article
Yu Ping Feng San, an Ancient Chinese Herbal Decoction, Regulates the Expression of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 and the Activity of Intestinal Alkaline Phosphatase in Cultures
PLoS ONE, v. 9, (6), June 2014, article number e100382
Du, Crystal Ying Qing; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David Tai Wai; Tsim, Karl Wah Keung Article
中药冬虫夏草的鉴别研究
中国药学杂志=Chinese Pharmaceutical Journal, v. 49, (4), February 2014, p. 283-286
徐红; 董婷霞; 赵奎君; 陈嘉伦; 林燕靖; 詹华强; 王峥涛 Article
紫草药材的HPLC指纹图谱研究及其β-乙酰氧基异戊酰阿卡宁的含量测定
China Pharmacy, (3), 2014, p. 262-265
Miernisha, A.; Dong, Ting Xia; Guo, A.J.Y.; Aisa, HA; Tsim, Karl Wah Keung Article
紫草药材的HPLC指纹图谱研究及其β-乙酰氧基异戊酰阿卡宁的含量测定
中国药房=China Pharmacy, v. 25, (3), 2014, p. 262-265
米尔尼沙·阿不都热依木; 董婷霞; 郭江扬; 阿吉·艾克拜尔艾萨; 詹华强 Article
Authenication of cervi cornu pantotrichum by microscopic and dna analysis
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Lam, Yin Ching; Xu, H.; Chan, Kar Lun Gallant; Xin, GZ; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Flavonoids originated from Chinese medicines possess neuroprotective effects on cultured neurons: Development of health food supplements in preventing Alzheimer's disease
Chinese Chemical Society 10th National Symposium on Natural Organic Chemistry, Guangzhou, China, 21-23 November 2014
Tsim, Karl Wah Keung Conference paper
Optimizing the compatibility of paired-herb in an ancient chinses herbal decoction kai-xin-san in activating neurofilamment expression in cultured pc12 cells
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Yan, Lu; Xu, SL; Zhu, Kevin Y.; Lam, Yin Ching; Xin, GZ; Li, N.; Yao, Ping; Lin, Huangquan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Quality Control of Cooking Oils by GC-MS Profiling and Spectral Fingerprinting
62nd ASMS Conference on Mass Spectrometry and Allied Topics 2014, Baltimore, MD, USA, 15-19 June 2014
Chan, Pui Hei Nicholas; Zhu, Y.; Tsim, Karl Wah Keung; Lam, Henry H N Conference paper
Resource development and biological evaluation: Nardostachyos Radix et Rhizoma and Dracocephali Moldavicae Herba
The 2014 International Seminar for Chinese Medicine & National Medical Resource and 11th Academic Annual Conference for Professional Committee of Natural Medicine Resource of China Society of National Resource, Nanjing, China, 15-18 October 2014
Tsim, Karl Wah Keung Conference paper
The chemical and biological studies of zao tang and jujube extract
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Lam, Ting Wai; Chen, Jianping; Yan, Lu; Lam, Yin Ching; Chan, Pui Hei Nicholas; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The pharmacological properties of calycosin-depleted danggui buxue tang
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Gong, Amy Guo-wei; Li, N.; Gao, QG; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The Quality Assurance of Edible Bird's Nest
Edible Bird Nest Industry Conference 2014, Putrajaya, Malaysia, 24-27 November 2014
Tsim, Karl Wah Keung Conference paper
The role of flavonoids, derived from traditional chinese medicine, in the production of erythropoetin
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Men, WX; Xu, SL; Lin, HQ; Dong, TTX; Tsim, Karl Wah Keung Conference paper
2013 28
Activation of UTP-Sensitive P2Y(2) Receptor Induces the Expression of Cholinergic Genes in Cultured Cortical Neurons: A Signaling Cascade Triggered by Ca2+ Mobilization and Extracellular Regulated Kinase Phosphorylation
Molecular Pharmacology, v. 84, (1), 2013, p. 50-61
Choi, Roy Chi Yan; Chu, Glanice K.Y.; Siow, Nina Lam; Yung, Amanda W.Y.; Yung, Lisa Ying; Lee, Pinky S.C.; Lo, Christopher C.W.; Simon, Joseph; Dong, Tina Ting Xia; Barnard, Eric A.; Tsim, Karl Wah Keung Article
Analysis of HPLC fingerprints and determination of isofraxidin and rosmarinic acid of Sarcandrae Herba from Sarcandra glabra (Thunb.) Nakai
China Pharmacy, v. 24, (47), 2013, p. 4472-4474
Tang, W.L.R.; Ng, Y.Y.; Bi, Dan; Duan, Ran; Tsim, Karl Wah Keung; Dong, Tina Ting Xia Article
Can Hedysari Radix replace Astragali Radix in Danggui Buxue Tang, a Chinese herbal decoction for woman aliment?
Phytomedicine, v. 20, (12), September 2013, p. 1076-1081
Zhang, Wendy Li; Choi, Roy Chi-Yan; Zhan, Janis Ya-Xian; Chen, Jian-Ping; Luk, Wilson Kin-Wai; Yao, Ping; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung Article
Chemical and Biological Assessment of Angelica Roots from Different Cultivated Regions in a Chinese Herbal Decoction Danggui Buxue Tang
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 483286
Zhang, Wendy L.; Zheng, Ken Y.Z.; Zhu, Kevin Y.; Zhan, Janis Y.X.; Bi, Cathy W.C.; Chen, J.P.; Dong, Tina T.X.; Choi, Roy C.Y.; Lau, David T.W.; Tsim, Karl W.K. Article
Chemical and Biological Assessment of Ziziphus jujuba Fruits from China: Different Geographical Sources and Developmental Stages
Journal of agricultural and food chemistry, v.61, (30), July 2013
Chen, Jianping; Li, Zhonggui; Maiwulanjiang, Maitinuer; Zhang, Wendy Li; Zhan, Janis Yaxian; Lam, Candy Ting Wai; Zhu, Kevin Yue; Yao, Ping; Choi, Chiyan; Lau, Taiwai; Dong, Tingxia; Tsim, Karl Wah Keung Article
Chemical changes of Angelicae Sinensis Radix and Chuanxiong Rhizoma by wine treatment: chemical profiling and marker selection by gas chromatography coupled with triple quadrupole mass spectrometry
Chinese Medicine (United Kingdom), v. 8, (1), June 2013, article number 12
Zhan, Janis Ya-Xian; Zhang, Wendy Li; Zheng, Ken Yu-zhong; Zhu, Kevin Yue; Chen, Jian-ping; Chan, Pui-Hei; Dong, Tina Ting-xia; Choi, Roy Chi-yan; Lam, Henry H N; Tsim, Karl Wah Keung; Lau, David Tai-wai Article
Chemical fingerprinting and quantitative analysis of two common Gleditsia sinensis fruits using HPLC-DAD
Acta Pharmaceutica, v. 63, (4), December 2013, p. 505-515
Chen, Jianping; Li, Zhonggui; Zheng, Ken Y.Z.; Guo, Ava J.Y.; Zhu, Kevin Y.; Zhang, Wendy L.; Zhan, Janis Y.X.; Dong, Tina T.X.; Su, Ziren; Tsim, Karl W.K. Article
Determination of free N-acetylneuraminic acid in edible bird nest: A development of chemical marker for quality control
Journal of Ethnobiology and Traditional Medicine, v. 120, October 2013, p. 620-628
Chan, Kar Lun Gallant; Zheng, Ken Yu Zhong; Zhu, Kevin Yue; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Distribution and expression of Kirre, an IgSF molecule, during postnatal development of rat cerebellum
Neuroscience Letters, v. 543, May 2013, p. 22-26
Kong, Lingwei; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Jing, Naihe; Nakayama, Don K.; Wang, Zhongbiao Article
Dual-Index Evaluation of Character Changes in Panax ginseng C. A. Mey Stored in Different Conditions
Journal of Agricultural and Food Chemistry, v. 61, (26), July 2013, p. 6568-6573
Li, Chen-yang; Lau, David Tai-wai; Dong, Tina Ting-xia; Zhang, Jian; Choi, Roy Chi-yan; Wu, Hai-qiang; Wang, Li-yan; Hong, Rui-sha; Li, Shi-he; Song, Xun; Yu, Tian; Su, Wei-wei; Tsim, Karl Wah Keung; He, Zhen-dan Article
Expression of cAMP-responsive Element Binding Proteins (CREBs) in Fast- and Slow-twitch Muscles: A Signaling Pathway to Account for the Synaptic Expression of Collagen-tailed Subunit (ColQ) of Acetylcholinesterase at the Rat Neuromuscular Junction
Chemico-biological Interactions, v. 203, (1), March 2013, p. 282-286
Choi, Roy Chi Yan; Chen, Ping; Luk, Wilson K.W.; Yung, Wai Yi; Ng, Alice H.M.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Flavonoids Induce the Expression of Synaptic Proteins, Synaptotagmin, and Postsynaptic Density Protein-95 in Cultured Rat Cortical Neuron
Planta Medica, v. 79, (18), December 2013, p. 1710-1714
Xu, Sherry Li; Zhu, Kevin Y; Bi, Wenchuan; Choi, Chi Yan; Miernisha, Abudureyimu; Yan, Artemis Lu; Maiwulanjiang, Maitinuer; Men, Simon W.X.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Flavonoids Induce the Synthesis and Secretion of Neurotrophic Factors in Cultured Rat Astrocytes: A Signaling Response Mediated by Estrogen Receptor
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013-06, article number 127075
Xu, Li; Bi, Wenchuan; Choi, Chi Yan; Zhu, Kevin Y; Miernisha, Abudureyimu; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Flavonoids, Derived from Traditional Chinese Medicines, Show Roles in the Differentiation of Neurons: Possible Targets in Developing Health Food Products
Birth Defects Research Part C: Embryo Today: Reviews, v. 99, (4), December 2013, p. 292-299
Xu, Li; Zhu, Kevin Y; Bi, Wenchuan; Yan, Lu; Men, Simon W.X.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
HPLC法同时测定浮小麦中5-二十一烷基间苯二酚和亚油酸的含量
中国药房=China Pharmacy, v. 24, (3), 2013, p. 244-246
高明菊; 毕 丹; 孟 霜; TANG Wai-lun; 徐 畅; 詹华强; 董婷霞 Article
Importance of Wine-Treated Angelica Sinensis Radix in Si Wu Tang, a Traditional Herbal Formula for Treating Women's Ailments
Planta Medica, v. 79, (7), May 2013, p. 533-537
Zhan, Yaxian; Zheng, Ken Y.Z.; Zhu, Kevin Y; Zhang, Li Wendy; Bi, Wenchuan; Chen, Jianping; Du, Crystal Ying Qing; Dong, Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Article
Kai-Xin-San, a Chinese Herbal Decoction Containing Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria, Stimulates the Expression and Secretion of Neurotrophic Factors in Cultured Astrocytes
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 731385
Zhu, Kevin Yue; Xu, Sherry Li; Choi, Roy Chi-Yan; Yan, Artemis Lu; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung Article
Optimizing Combinations of Flavonoids Deriving from Astragali Radix in Activating the Regulatory Element of Erythropoietin by a Feedback System Control Scheme
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 541436
Yu, Hui; Zhang, Wendy Li; Ding, Xianting; Zheng, Ken Yu Zhong; Ho, Chih-Ming; Tsim, Karl Wah Keung; Lee, Yi-Kuen Article
Perimenopause Amelioration of a TCM Recipe Composed of Radix Astragali, Radix Angelicae Sinensis, and Folium Epimedii: An In Vivo Study on Natural Aging Rat Model
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 747240
Su, Ji-Yan; Xie, Qing-Feng; Liu, Wei-Jin; Lai, Ping; Liu, Dan-Dan; Tang, Li-Hai; Dong, Tina Ting Xia; Su, Zi-Ren; Tsim, Karl Wah Keung; Lai, Xiao-Ping; Li, Kun-Yin Article
Song Bu Li Decoction, a Traditional Uyghur Medicine, Protects Cell Death by Regulation of Oxidative Stress and Differentiation in Cultured PC12 Cells
Evidence-Based Complementary and Alternative Medicine, v. 2013, 2013, article number 687958
Maiwulanjiang, Maitinuer; Zhu, Kevin Y.; Chen, Jianping; Abudureyimu miernisha; Xu, Li; Crystal y.q. du; Lau, Kei Man; Choi, Roy C.Y.; Dong, Tina T.X.; Aisa, Haji A.; Tsim, Karl W.K. Article
Surveillance of nitrite level in cubilose: Evaluation of removal method and proposed origin of contamination
Food Control, v. 34, (2), December 2013, p. 637-644
Chan, Gallant Kar Lun; Zhu, Kevinyue; Chou, David J.Y.; Guo, Ava Jiang Yang; Dong, Tinatingxia; Tsim, Karl Wah Keung Article
Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease
Evidence-Based Complementary and Alternative Medicine, v. 2013, 2013, article number 635694
Choi, Roy C.Y.; Zhu, Judy T.T.; Yung, Amanda W.Y.; Lee, Pinky S.C.; Xu, Sherry L.; Guo, Ava J.Y.; Zhu, Kevin Y.; Dong, Tina T.X.; Tsim, Karl W.K. Article
Yu Ping Feng San, an Ancient Chinese Herbal Decoction Containing Astragali Radix, Atractylodis Macrocephalae Rhizoma and Saposhnikoviae Radix, Regulates the Release of Cytokines in Murine Macrophages
PLoS ONE, v. 8, (11), November 2013, article number e78622
Du, Yingqing; Choi, Chi Yan; Zheng, Ken Yu Zhong; Dong, Ting Xia Tina; Lau, D.T.W.; Tsim, Karl Wah Keung Article
射干的质量标准研究
中国药房=China Pharmacy, v. 24, (11), 2013, p. 1023-1025
梁丽娟; 董婷霞; 詹华强; 赵奎君 Article
山豆根急性毒性实验研究
时珍国医国药=Lishizhen Medicine and Materia Medica Research, (4), 2013, p. 771-773
王平; 吴熙; 李俊鹏; 谢天柱; 邬晓鸥; 王晓炜; 文屏; 詹华强; 李军 Article
穿心莲质量标准研究
中国中医药信息杂志=Chinese Journal of Information on TCM, v. 20, (9), September 2013, p. 63-65
梁丽娟; 赵奎君; 董婷霞; 詹华强 Article
肿节风药材的HPLC指纹图谱研究及其异嗪皮啶与迷迭香酸的含量测定
中国药房=China Pharmacy, v. 24, (47), 2013, p. 4472-4474
邓伟麟; 吴莹莹; 毕丹; 段然; 詹华强; 董婷霞 Article
韭菜子的生药学研究
中国药房=China Pharmacy, v. 24, (3), 2013, p. 246-248
徐 红; 董婷霞; 林燕靖; 邓伟麟; 詹华强; 王峥涛 Article
2012 31
A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats
Evidence-based complementary and alternative medicine, v. 2012, 2012, Article number 149256
Zhu, Kevin Yue; Mao, Qing-Qiu; Ip, Siu-Po; Choi, Roy Chi-Yan; Dong, Tina Ting-Xia; Lau, David Tai-Wai; Tsim, Karl Wah Keung Article
Acetylcholinesterase: old questions and new developments
Frontiers in Molecular Neuroscience, v.5, 2013, Jan
Tsim, Karl Wah Keung; Soreq, Hermona Article
Application of Complementary and Alternative Medicine on Neurodegenerative Disorders: Current Status and Future Prospects
Evidence-based complementary and alternative medicine, v.2012, 2012, Article number 930908
Ip, Paul Siu-Po; Tsim, Karl Wah Keung; Chan, Kelvin; Bauer, Rudolf Article
Chemical and biological assessment of Angelica herbal decoction: Comparison of different preparations during historical applications
Phytomedicine, v. 19, (11), August 2012, p. 1042-1048
Zhang, Li Wendy; Zheng, Ken Y Z; Zhu, Kevin Y; Zhan, Yaxian; Bi, Wenchuan; Chen, Jianping; Du, Y.; Zhao, Kuijun; Lau, David T W; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Effect of a derived herbal recipe from an ancient Chinese formula, Danggui Buxue Tang, on ovariectomized rats
Journal of ethnopharmacology, v. 144, (3), December 2012, p. 567-575
Xie, Qing-Feng; Xie, Jian-Hui; Dong, Tina T.X.; Su, Ji-Yan; Cai, Da-Ke; Chen, Jian-Ping; Liu, Liang-Feng; Li, Yu-Cui; Lai, Xiao-Ping; Tsim, Karl Wah Keung; Su, Zi-Ren Article
Er Zhi Wan, an ancient herbal decoction for woman menopausal syndrome, activates the estrogenic response in cultured MCF-7 cells: An evaluation of compatibility in defining the optimized preparation method
Journal of ethnopharmacology, v. 143, (1), August 2012, p. 109-115
Xu, Hong; Su, Zi-Ren; Huang, Wen; Choi, Roy Chi-Yan; Zheng, Yu-Zhong; Lau, David Tai-Wai; Dong, Tina Ting-Xia; Wang, Zheng-Tao; Tsim, Karl Wah Keung Article
Fo Shou San, an Ancient Chinese Herbal Decoction, Protects Endothelial Function through Increasing Endothelial Nitric Oxide Synthase Activity
PLoS ONE, v. 7, (12), 2012, article no. e51670
Bi, Cathy W.C.; Xu, Li; Tian, Xiao Yu; Liu, Jian; Zheng, Ken Y.Z.; Lau, Chi Wai; Lau, David Tai Wai; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Huang, Yu; Tsim, Karl Wah Keung Article
HPLC-ELSD测定肉苁蓉及管花肉苁蓉中半乳糖醇含量
中国中医药信息杂志=Chinese Journal of Information on Traditional Chinese Medicine, v. 19, (8), 2012, p. 52-54
赵奎君; 梁丽娟; 毕丹; 董婷霞; 詹华强 Article
Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor
Evidence-Based Complementary and Alternative Medicine, v. 2012, 2012 article number 278273
Xu, Sherry L.; Choi, Roy C.Y.; Zhu, Kevin Y.; Leung, Ka-Wing; Guo, Ava J.Y.; Bi, Dan; Xu, Hong; Lau, David T.W.; Dong, Tina T.X.; Tsim, Karl W.K. Article
Kaempferol as a flavonoid induces osteoblastic differentiation via estrogen receptor signaling
Chinese Medicine, v. 7, (10), April 2012
Guo, Ava Jiangyang; Choi, Roy Chiyan; Zheng, Ken Yuzhong; Chen, Vicky Ping; Dong, Tina Tingxia; Wang, Zheng-Tao; Vollmer, Günter; Lau, David Taiwai; Tsim, Karl Wah Keung Article
Metabonomic analysis of water extracts from Chinese and American ginsengs by H-1 nuclear magnetic resonance: identification of chemical profile for quality control
Chinese medicine, v. 7, November 2012, Article number 25
Chan, Pui Hei; Zheng, Ken Y.Z.; Tsim, Karl Wah Keung; Lam, Henry H N Article
Microfluidic chip based nano liquid chromatography coupled to tandem mass spectrometry for the determination of abused drugs and metabolites in human hair
Analytical and bioanalytical chemistry, v. 402, (9), March 2012, p. 2805-2815
Zhu, Kevin Yue; Leung, Ka Wing; Ting, Annie K.L.; Wong, Zack C.F.; Ng, Winki Y.Y.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wang, Tiejie; Lau, David Tai Wai; Tsim, Karl Wah Keung Article
N-linked glycosylation of dimeric acetylcholinesterase in erythrocytes is essential for enzyme maturation and membrane targeting
The FEBS journal, v. 279, (17), September 2012, p. 3229-3239
Luk, Wilson Kin Wai; Chen, Vicky Ping; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase
Neuroscience Letters, v. 523, (1), August 2012, p. 71-75
Chan, Wallace Kin Bon; Chen, Vicky Ping; Luk, Wilson K.W.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Salidroside Stimulates the Accumulation of HIF-1 Alpha Protein Resulted in the Induction of EPO Expression: A Signaling via Blocking the Degradation Pathway in Kidney and Liver Cells
European Journal of Pharmacology, v. 679, (1-3), March 2012, p. 34-39
Zheng, Ken Y Z; Zhang, Zhenxia; Guo, A.J.Y.; Bi, Wenchuan; Zhu, Kevin Y; Xu, Li; Zhan, Yaxian; Lau, David T W; Dong, Ting Xia; Choi, Chi Yan; Tsim, Karl Wah Keung Article
The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: A synergistic action of an ancient herbal decoction Danggui Buxue Tang
Journal of pharmaceutical and biomedical analysis, v. 70, 2012, p. 671-679
Zheng, Ken Yu Zhong; Choi, Roy Chi Yan; Guo, Ava Jiang Yang; Bi, Cathy Wei Chuan; Zhu, Kevin Yue; Du, Crystal Ying Qing; Zhang, Zhen Xia; Lau, David Tai Wai; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress
Journal of ethnopharmacology, v. 139, (1), 2012, p. 214-220
Wang, T.; Choi, Roy Chi Yan; Li, J.; Bi, Cathy Wei Chuan; Ran, W.; Chen, X.; Dong, Tina Ting Xia; Bi, K.; Tsim, Karl Wah Keung Article
A flavonol aglycone isorhamnetin possesses neuronal differentiation activity in PC12 cells via the potentiation of NGF on neurite outgrowth
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Xu, SL; Choi, Roy Chi Yan; Zhu, KY; Guo, AJY; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Conference paper
An ancient paired-herbal decoction Fo Shou San, stimulates the blood and circulation functions
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Bi, CWC; Xu, SL; Lau, David Tai Wai; Choi, RCY; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Blood circulation effect of Angelica Radix Sinensis: anti-platelet aggregation and ENTPD gene regulation in human endothelial cells
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Ng, AHM; Choi, RCY; Lau, DTW; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Characterization of Acetylcholinesterase in Oyster, Crassostrea Gigas
11th International Meeting on Cholinesterases, Russia, 2012
Dong, Ting Xia; Sit, BHM; Chen, VP; Chan, Kin Bon Wallace; Luk, WKW; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Chromatographic fingerprint and determination of 5-heneicosylresorcinol and linoleic acid in Fructus Tritici Levis by HPLC
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Bi, Dan; Tang, RWL; Dong, Tina Ting Xia; Wang, ZT; Tsim, Karl Wah Keung Conference paper
Dynamic change of flavonoids during the preparation of Danggui Buxue Tang: an outcome of moderate boiling of Chinese herbal mixture
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Zhang, WL; Zheng, KYZ; Zhu, KY; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Investigation on the bioactive compounds of Chinese dates at two stages of maturity from young or historical trees
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Cheng, JP; Guo, AJY; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Conference paper
Mechanistic study of Yu Ping Feng San-mediated the inhibition of intestinal P-glycoprotein efflux transporter to enhance the bioavailability of Astragali Radix-derived calycosin in Caco-2 cell monolayers
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Du, CYQ; Zheng, KYZ; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Conference paper
Molecular Assembly of Acetylcholinesterase-H Form in Erythrocyte
11th International Meeting on Cholinesterases, Russia, 2012
Luk, WKW; Chen, VP; Choi, RCY; Chan, WKB; Tsim, Karl Wah Keung Conference paper
Neuroprotection effect of Angelica Sinensis Radix against oxidative stress in PC12 neurons
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Yung, AWY; Ng, AHM; Choi, RCY; Dong, Tina Ting Xia; Lau, DTW; Tsim, Karl Wah Keung Conference paper
Studies on pharmacognosy of Lonicerae Japonicae Flos
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Lam, KYC; Dong, Tiina Ting Xia; Wong, ZT; Tsim, Karl Wah Keung Conference paper
The study of the removal methods and the origin of nitrite in edible bird's nest
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Chan, GKL; Zheng, KYZ; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
The wine treatment on Angelicae Sinensis Radix and Chuanxiong Rhizoma: chemical distinction by using triple quadrupole gas chromatography
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, Chimna, 18-19 May 2012
Zhan, JYX; Zhang, WL; Zheng, KYZ; CHENG, JP; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Conference paper
Traditional Uyghur medicine - Song Bu Li, a decoction from Nardostachyos Radix et Rhizoma: development of quality control parameter and evaluation of the biological functions
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Maitinuer, M.; Choi, RCY; Aisa, HA; Lau, DTW; Dong, Tina Ting Xia; Wang, ZT; Tsim, Karl Wah Keung Conference paper
2011 16
A Chinese Herbal Decoction, Danggui Buxue Tang, Stimulates Proliferation, Differentiation and Gene Expression of Cultured Osteosarcoma Cells: Genomic Approach to Reveal Specific Gene Activation
Evidence-based complementary and alternative medicine, (307548), 2011, p. 1-13
Choi, Roy Chi Yan; Gao, Qiu T.; Cheung, Anna Wing Han; Zhu, Judy Ting Ting; Lau, Faye T.C.; Li, Jun; Li, Winnie Z.M.; Chu, Glanice K.Y.; Duan, Ran; Cheung, Jerry K.H.; Ding, An W.; Zhao, Kui J.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Analysis of HPLC fingerprints of Fructus Aurantii from different habitats and contents of naringin, neohesperidin and synephrine
中国药学杂志, v. 46, (12), 2011, p. 955-959
Zhao, Kuijun; Zheng, Yuzhong; Dong, Tingxia; Tsim, Karl Wah Keung Article
Baicalin, a Flavone, Induces the Differentiation of Cultured Osteoblasts AN ACTION VIA THE Wnt/β-CATENIN SIGNALING PATHWAY
Journal of biological chemistry, v. 286, (32), August 2011, p. 27882-27893
Guo, Ava Jiang Yang; Choi, Roy Chi Yan; Cheung, Anna W.H.; Chen, Vicky Ping; Xu, Sherry Li; Dong, Tina Ting Xia; Chen, Ji J.; Tsim, Karl Wah Keung Article
Chemical and Biological Assessment of Angelicae Sinensis Radix after Processing with Wine: An Orthogonal Array Design To Reveal the Optimized Conditions
Journal of agricultural and food chemistry, v. 59, (11), June 2011, p. 6091-6098
Zhan, Janis Y.X.; Zheng, Ken Yu Zhong; Zhu, Kevin Yue; Bi, Cathy Wei Chuan; Zhang, Wendy L.; Du, Crystal Ying Qing; Fu, Qiang; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Lau, David Tai Wai Article
Chemical and DNA authentication of taste variants of Gynostemma pentaphyllum herbal tea
Food chemistry, v. 128, (1), September 2011, p. 70-80
Wu, Pui Kei; Tai, William C.S.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Zhou, Hua; Liu, Xin; Jiang, Zhi-Hong; Hsiao, W. L. Wendy Article
Expression of the IgSF protein Kirre in the rat central nervous system
Life sciences, v. 88, (13-14), 2011, p. 590-597
Kong, L.; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Wang, X.; Peng, G.; Xie, Z.; Tsim, Karl Wah Keung; Jing, N. Article
Flavonoids from Radix Astragali Induce the Expression of Erythropoietin in Cultured Cells: A Signaling Mediated via the Accumulation of Hypoxia-Inducible Factor-1α
Journal of Agricultural and Food Chemistry, v. 59, (5), 2011, p. 1697-1704
Zheng, Ken Y Z; Choi, Chi Yan; Cheung, Wing Han; Guo, A.J.Y.; Bi, Wenchuan; Zhu, Kevin Y; Fu, Qiang; Du, Yingqing; Zhang, Li Wendy; Zhan, Janis Y.X.; Duan, Ran; Lau, David T W; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Fo Shou San, an ancient herbal decoction prepared from Angelicae Sinensis Radix and Chuanxiong Rhizoma, induces erythropoietin expression: A signaling mediated by the reduced degradation of hypoxia-inducible factor in cultured liver cells
Planta medica, v. 78, (2), November 2011, p. 122-127
Bi, Wenchuan; Xu, Li; Zhang, Li Wendy; Zhan, Yaxian; Fu, Qiang; Zheng, Ken Y Z; Chen, Ping; Lau, David T W; Choi, Chi Yan; Wang, Tiejie; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Molecular Assembly and Biosynthesis of Acetylcholinesterase in Brain and Muscle: the Roles of t-peptide, FHB Domain, and N-linked Glycosylation
Frontiers in Molecular Neuroscience, v. 4, 2011, article number 36
Chen, Vicky P.; Luk, Wilson K.W.; Chan, Wallace K.B.; Leung, K. Wing; Guo, Ava J.Y.; Chan, Gallant K.L.; Xu, Sherry L.; Choi, Chi Yan; Tsim, Karl Wah Keung Article
Phenolic compounds from the rhizomes of dioscorea bulbifera
Chemistry & biodiversity, v. 8, (11), 2011, p. 2110-2116
Liu, Hai; Tsim, Karl Wah Keung; Chou, Guixin; Wang, Junming; Ji, Lili; Wang, Zhengtao Article
The Assembly of Proline-rich Membrane Anchor (PRiMA)-linked Acetylcholinesterase Enzyme GLYCOSYLATION IS REQUIRED FOR ENZYMATIC ACTIVITY BUT NOT FOR OLIGOMERIZATION
Journal of biological chemistry, v. 286, (38), September 2011, p. 32948-32961
Chen, Vicky P.; Choi, Roy C.Y.; Chan, Wallace K.B.; Leung, K. Wing; Guo, Ava J.Y.; Chan, Kar Lun Gallant; Luk, Wilson K.W.; Tsim, Karl Wah Keung Article
The establishment of a highly sensitive method in detecting ketamine and norketamine simultaneously in human hairs by HPLC-Chip-MS/MS
Forensic science international, v. 208, May 2011, p. 53-58
Zhu, Kevin Yue; Leung, Ka Wing; Ting, Annie K.L.; Wong, Zack Chun Fai; Fu, Qiang; Ng, Winki Y.Y.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wang, Tiejie; Lau, David Tai Wai; Tsim, Karl Wah Keung Article
The establishment of a sensitive method in determining different neurotransmitters simultaneously in rat brains by using liquid chromatography-electrospray tandem mass spectrometry
Journal of chromatography. B, v. 879, April 2011, p. 737-742
Zhu, Kevin Yue; Fu, Qiang; Leung, Ka Wing; Wong, Zack Chun Fai; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
The Extract of Rhodiolae Crenulatae Radix et Rhizoma Induces the Accumulation of HIF-1 alpha via Blocking the Degradation Pathway in Cultured Kidney Fibroblasts
Planta medica, v. 77, (9), June 2011, p. 894-899
Zheng, Ken Yu Zhong; Guo, Ava Jiang Yang; Bi, Cathy Wei Chuan; Zhu, Kevin Yue; Chan, Kar Lun Gallant; Fu, Qiang; Xu, Sherry Li; Zhan, Janis Y.Z.; Lau, David Tai Wai; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
不同产地枳壳药材HPLC指纹图谱及其柚皮苷、新橙皮苷和辛弗林含量分析
中国药学杂志=Chinese Pharmaceutical Journal, v. 2011, (12), 2011, p. 955-959
赵奎君; 郑玉忠; 董婷霞; 詹华强 Article
1H-NMR metabonomics analysis of Danggui Buxue Tang effects in HEK293T kidney cell lines
China Human Proteome Organization (CNHUPO) 7th Annual Congress, Hangzhou, China, 2011
Chan, Pui Hei Nicholas; Tsim, Karl Wah Keung; Lam, Henry H N Conference paper
2010 35
A Flavonol Glycoside, Isolated From Roots of Panax notoginseng, Reduces Amyloid-beta-Induced Neurotoxicity in Cultured Neurons: Signaling Transduction and Drug Development for Alzheimer's Disease
JOURNAL OF ALZHEIMERS DISEASE, v. 19, (3), 2010, p. 795-811
Choi, Roy Chi Yan; Zhu, Judy Ting Ting; Leung, Ka Wing; Chu, Glanice K.Y.; Xie, Heidi Qunhui; Chen, Vicky Ping; Zheng, Ken Yu Zhong; Lau, David Tai Wai; Dong, Tina Ting Xia; Chow, Peter C.Y.; Han, Yi-Fan; Wang, Zheng-Tao; Tsim, Karl Wah Keung Article
An induction effect of heat shock on the transcript of globular acetylcholinesterase in NG108-15 cells
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), 2010, SEP 6, p. 106-109
Chen, Vicky Ping; Xie, Heidi Qunhui; Chan, Wallace Kin Bon; Leung, Ka Wing; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Antihyperlipidemic Effect of Protodioscin, an Active Ingredient Isolated from the Rhizomes of Dioscorea nipponica
Planta Med., 76, 15, May 2010, p. 1642-1646
Wang, Tiejie; Choi, Chi Yan; Li, Jun; Bi, Wenchuan; Zang, Linquan; Liu, Zhongbo; Dong, Tingxia; Bi, Kaishun; Tsim, Karl Wah Keung Article
Anti-oxidative effects of the biennial flower of Panax notoginseng against H2O2-induced cytotoxicity in cultured PC12 cells
Chinese Medicine, v. 5, 2010
Choi, Roy Chi Yan; Jiang, Z.; Xie, Heidi Qunhui; Cheung, Anna Wing Han; Lau, David Tai Wai; Fu, Qiang; Dong, Tina Ting Xia; Chen, J.; Wang, Z.; Tsim, Karl Wah Keung Article
ATP induces synaptic gene expressions in cortical neurons: Transduction and transcription control via P2Y1 receptors
Molecular Pharmacology, v. 78, (6), 2010, p. 1059-1071
Siow, Nina Lam; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Kong, L.W.; Chu, G.K.Y.; Chan, Kar Lun Gallant; Simon, J.; Barnard, E.A.; Tsim, Karl Wah Keung Article
Differential gene expression profiling on the muscle of acetylcholinesterase knockout mice: A preliminary analysis
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), 2010, SEP 6, p. 120-123
Lin, Huang-Quan; Choi, Roy Chi Yan; Chan, Kam-Leung; Ip, Denis; Tsim, Karl Wah Keung; Wan, David Chi-cheong Article
Expression and Localization of PRiMA-Linked Globular Form Acetylcholinesterase in Vertebrate Neuromuscular Junctions
Journal of Molecular Neuroscience, v. 40, (1-2), January 2010, p. 40-46
Tsim, Karl Wah Keung; Leung, Ka Wing; Mok, Ka Wai; Chen, Ping; Zhu, Kevin Y; Zhu, Judy T T; Guo, A.J.Y.; Bi, Wenchuan; Zheng, Ken Y Z; Lau, David T W; Xie, Qunhui; Choi, Chi Yan Article
Fo Shou San, an Ancient Herbal Decoction Prepared from Rhizoma Chuanxiong and Radix Angelicae Sinensis, Stimulates the Production of Hemoglobin and Erythropoietin in Cultured Cells
Planta medica, v. 76, (14), October 2010, p. 1525-1529
Bi, Wenchuan; Xie, Qunhui; Xu, Li; Li, Jun; Cheung, Wing Han; Zhu, Judy T T; Zheng, Ken Y Z; Chen, Ping; Lau, David T W; Choi, Chi Yan; Wang, Tie Jie; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), September 2010, p. 246-248
Guo, Ava Jiang Yang; Xie, Heidi Qunhui; Choi, Roy Chi Yan; Zheng, Ken Yu Zhong; Bi, Wenchuan; Xu, Sherry Li; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Nerve Growth Factor-Induced Differentiation of PC12 Cells Is Accompanied by Elevated Adenylyl Cyclase Activity
NeuroSignals, v. 18, (1), September 2010, p. 32-42
Yung, H.S.; Lai, K.H.; Chow, Kevin B.S.; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung; Wong, Yung Hou; Wu, Zhenguo; Wise, Helen Article
PRiMA directs a restricted localization of tetrameric AChE at synapses
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), September 2010, p. 78-83
Xie, Qunhui; Leung, Ka Wing; Chen, Ping; Chan, Kar Lun Gallant; Xu, Li; Guo, A.J.Y.; Zhu, Kevin Y; Zheng, Ken Y Z; Bi, Weichuan; Zhan, Yaxian; Chan, Kin Bon Wallace; Choi, Chi Yan; Tsim, Karl Wah Keung Article
Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae
Journal of Separation Science, v. 33, (23-24), 2010, p. 3666-3674
Zhu, Kevin Yue; Fu, Qiang; Xie, Heidi Qunhui; Xu, S.L.; Cheung, Anna Wing Han; Zheng, Ken Yu Zhong; Luk, W.K.W.; Choi, Roy Chi Yan; Lau, David Tai Wai; Dong, Tina Ting Xia; Jiang, Z.Y.; Chen, J.J.; Tsim, Karl Wah Keung Article
Quality Evaluation of Radix Glehniae (Glehnia littoralis) by HPLC-DAD: Chromatographic Fingerprinting and Quantitative Analysis of the Herbs from Different Regions of China
Asian Journal of Traditional Medicines 2010, v. 5, (2), 2010, p. 40-48
Li, Jun; Cheung, Wing Han; Bi, Wenchuan; Duan, Ran; Zheng, Ken Y Z; Huang, Wen; Chen, Ji J.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Synthesis and Anti-inflammatory Activity of a Novel Series of 9,10-Dihydro-4H,8H-chromeno [8,7-e][1,3]oxazin-4-one Derivatives
Chemical Research in Chinese Universities, v. 26, (2), 2010, MAR 25, p. 268-271
Liu, Xiao-ping; Wang, Ying; Lan, Hui-yu; Song, Ai-hua; Tsim, Karl Wah Keung; Dong Tina, Ting-xia; Hu, Chun Article
Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons
Journal of Biological Chemistry, v. 285 (15), pp. 11537-11546
Xie, Heidi Qunhui; Liang, Dong; Leung, Ka Wing; Chen, Vicky Ping; Zhu, Kevin Yue; Chan, Wallace Kin Bon; Choi, Roy Chi Yan; Massoulié, Jean; Tsim, Karl Wah Keung Article
The expression of erythropoietin triggered by Danggui Buxue Tang, a Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells
Journal of Ethnopharmacology, v. 132, (1), October 2010, p. 259-267
Zheng, Ken Y Z; Choi, Chi Yan; Xie, Qunhui; Cheung, Wing Han; Guo, A.J.Y.; Leung, Ka Wing; Chen, Ping; Bi, Weichuan; Zhu, Kevin Y; Chan, Kar Lun Gallant; Fu, Qiang; Lau, David T W; Dong, Ting Xia; Zhao, K.J.; Tsim, Karl Wah Keung Article
The PRiMA-linked cholinesterase tetramers are assembled from homodimers hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain
Journal of biological chemistry, v. 285, (35), 2010, AUG 27, p. 27265-27278
Chen, Vicky Ping; Xie, Heidi Qunhui; Chan, Wallace Kin Bon; Leung, Ka Wing; Chan, Kar Lun Gallant; Choi, Roy Chi Yan; Bon, Suzanne; Massoulie, Jean; Tsim, Karl Wah Keung Article
黄芪中7种活性成分对缺氧诱导因子(HIF-1)表达的影响
中国药房=China Pharmacy, v. 2010, (47), 2010, p. 4422-4424
梁丽娟; 董婷霞; 詹华强; 屠鹏飞; 赵奎君 Article
"Female ginseng" – DANGGUI (当归): study on chemical profile after wine-processing
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Zhan, JYX; Zheng, KYZ; Bi, CWC; Zhu, KY; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
A new species of cholinesterase in chicken brain: PRiMA-linked AChE-BChE hybrid tetramer
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chen, VP; Chan, Kin Bon Wallace; Leung, Ka Wing; Zhang, VQ; Chan, GKL; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
A novel authentication method on edible bird nest by TripleQuad LC-MS/MS
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, XINJIANG CHINA, 2010
Chan, GKL; Li, J.; Wang, SH; Wang, TJ; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
A novel G-protein-coupled receptor complex: heterodimerization of purinergic P2Y1 and P2Y2 receptors
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chan, GKL; Leung, Ka Wing; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Acetylcholinesterase in erythrocytes: A non-cholinergic role in regulating erythropoiesis
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, 2010
Zhang, VQ; Chen, VP; Guo, AJY; Chan, GKL; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Aqueous extract of the root and rhizome of Rhodiola crenuclata induces the accumulation of HIF-1α via blocking the degradation pathway
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, , 2010
Zheng, KYZ; Guo, AJY; Bi, CWC; Zhu, KY; Xu, SL; Zhan, JYX; Chan, GKL; Cheung, Wing Han; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Authentication of dendrobium species by DNA sequencing method: clarification of the definition of Chinese pharmacopeia
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Chan, GKL; Jiang, ZW; Choi, Roy Chi Yan; Lau, David T W; Tsim, Karl Wah Keung Conference paper
Combination of baicalein and daidzein synergistically enhanced the estrogenic and neuroprotective effects: drug development against Alzheimer's disease
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Guo, AJY; Xu, SL; Zheng, KYZ; Cheung, Wing Han; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Estrogenic and neuroprotective effects of baicalein and daizein: drug development against Alzheimer's disease
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Guo, AJY; Cheung, Wing Han; Zhu, KY; Zheng, KYZ; Xu, SL; Lau, David T W; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Fo Shou San, an ancient herbal decoction prepared from Angelica Sinensis Radix and Chuangxiong Rhizoma, stimulates the production of hemoglobin and erythropoietin in cultured cells
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang China, 2010
Bi, CWC; Xie, HQ; Xu, SL; Li, Jun; Cheung, Wing Han; Zheng, KYZ; Lau, DTW; Choi, Chi Yan; Wang, TJ; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Investigation of KAI XIN SAN (开心散) and DING ZHI WAN (定志丸) – two traditional herbal formulae in treating mental disorder elucidation of action mechanism with chemical and biological methods
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, XINJIANG CHINA, 2010
Zhu, KY; Choi, Roy Chi Yan; Luk, WKW; Lau, David T W; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Neuroprotective and neurogenic effect of flavnoids derived from the traditional Chinese medicines
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Xu, SL; Guo, AJY; Cheung, Wing Han; Zhu, KY; Zheng, KYZ; Lau, David T W; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Objectives, delivery and assessment – adoption of the outcome-based education triangular philosophy and methodologies at the program level of a biology program
TARC International Conference on Learning and Teaching TIC2010, Tunku Abdul Rahman College, Malaysia, 18-19, Oct, 2010
Yu, L.; Siow, NL; Tsim, Karl Wah Keung; Chow, King Lau Conference paper
Post-translational modification of PRiMA-linked G4 AChE by glycosylation
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chan, Kin Bon Wallace; Chen, VP; Leung, Ka Wing; Zhang, VQ; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Promoting students' personal development through biology co-curriculum in partnership with non-academic units
TARC International Conference on Learning and Teaching TIC2010, Tunku Abdul Rahman College, Malaysia. October 18-19, 2010
KO, IWP; Chow, King Lau; Ren, YY; Tsim, Karl Wah Keung Conference paper
Tandem mass spectrometric analysis of triterpene saponins in Weilingxian (Roots and Rhizomes of Clematis chinensis) by RRLC-DAD-ESI-MSn
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang China, 2010
Fu, Q.; Zan, K.; Zhao, MB; Zhou, SX; Shi, SP; Tu, PF; Tsim, Karl Wah Keung Conference paper
The optimization of wine-processing of Angelica Sinensis Radix via chemical assessment and GC-MS fingerprinting
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang, China, 2010
Zhan, JYX; Zheng, KYZ; Bi, CWC; Zhu, KY; Fu, Q.; Duan, Ran; Lau, David T W; Dong, Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
2009 19
A new variant of proline-rich membrane anchor (PRiMA) of acetylcholinesterase in chicken: Expression in different muscle fiber types
Neuroscience Letters, v. 461, (2), 2009, SEP 11, p. 202-206
Mok, Mokka K.W.; Leung, Ka Wing; Xie, Heidi Qunhui; Guo, Ava Jiang Yang; Chen, Vicky Ping; Zhu, Judy Ting Ting; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Can Rhizoma Chuanxiong Replace Radix Angelica Sinensis in the Traditional Chinese Herbal Decoction Danggui Buxue Tang?
Planta medica, v. 75, (6), May 2009, p. 602-606
Li, W.Z.M.; Li, Jun; Bi, Wenchuan; Cheung, Anna Wing Hsn; Huang, Wen; Duan, Ran; Choi, Roy Chi Yan; Chen, Ivy S.Y.; Zhao, Kuijun; Dong, Ting Xia; Duan, Jin A.; Tsim, Karl Wah Keung Article
Cordysinocan, a Polysaccharide Isolated from Cultured Cordyceps, Activates Immune Responses in Cultured T-lymphocytes and Macrophages: Signaling Cascade and Induction of Cytokines
Journal of Ethnopharmacology, v. 124, (1), July 2009, p. 61-68
Cheung, Ka Hei; Li, Jun; Cheung, Wing Han; Zhu, Kevin Y; Zheng, Ken Y Z; Bi, Wenchuan; Duan, Ran; Choi, Chi Yan; Lau, David T W; Dong, Ting Xia; Lau, Brad W.C.; Tsim, Karl Wah Keung Article
Differential and Synergistic Effect of Nerve Growth Factor and cAMP on the Regulation of Early Response Genes during Neuronal Differentiation
NeuroSignals, v. 17, (2), May 2009, p. 111-120
Ng, Yu Pong; Wu, Zhenguo; Wise, Helen; Tsim, Karl Wah Keung; Wong, Yung Hou; Ip, Nancy Yuk-Yu Article
Effect of Extraction Solvent on the Bioactivity of an Herbal Formulation
Industrial and Engineering Chemistry Research, v. 48, (10), May 2009, p. 4852-4857
Chan, Kin N.; Lau, Choi C.; Chow, King Lau; Ko, Robert Kam Ming; Tsim, Karl Wah Keung; Ng, Ka Ming Article
Estrogenic and Neuroprotective Properties of Scutellarin from Erigeron breviscapus: A Drug against Postmenopausal Symptoms and Alzheimer's Disease
Planta medica, v. 75, (14), June 2009, p. 1489-1493
Zhu, Judy T T; Choi, Chi Yan; Li, Jun; Xie, Qunhui; Bi, Wenchuan; Cheung, Wing Han; Dong, Ting Xia; Jiang, Zhiyong; Chen, Jijun; Tsim, Karl Wah Keung Article
Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons
Neuroscience Letters, v. 461, (2), September 2009, p. 172-176
Zhu, Judy T T; Choi, Chi Yan; Xie, Qunhui; Zheng, Ken Y Z; Guo, A.J.Y.; Bi, Wenchuan; Lau, David T W; Li, Jun; Dong, Ting Xia; Lau, Brad W.C.; Chen, Ji J.; Tsim, Karl Wah Keung Article
HPLC法测定女贞子药材中女贞苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 29, (5), 2009, p. 824-826
黄雯; 苏子仁; 毕文川; 李军; 施丽琼; 文英强; 詹华强 Article
HPLC测定当归补血片中黄芪甲苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 29, (9), 2009, p. 1553-1555
刘玮锦; 蔡大可; 刘亮锋; 赖平; 董婷霞; 詹华强; 苏子仁 Article
Ligustilide Suppresses the Biological Properties of Danggui Buxue Tang: A Chinese Herbal Decoction Composed of Radix Astragali and Radix Angelica sinensis
Planta medica, v. 76, (5), October 2009, p. 439-443
Zheng, Ken Yu Zhong; Choi, Roy Chi Yan; Li, Jun; Xie, Heidi Qunhui; Cheung, Anna Wing Han; Duan, Ran; Guo, Ava Jiang Yang; Zhu, Judy Ting Ting; Chen, Vicky Ping; Bi, Wenchuan; Zhu, Kevin Yue; Lau, David Tai Wai; Dong, Tina Ting Xia; Lau, Brad Wing Chuen; Tsim, Karl Wah Keung Article
Quality Evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by Using High-performance Liquid Chromatography Coupled with Diode Array Detector and Mass Spectrometry
Journal of Chromatography A, v. 1216, (11), March 2009, p. 2071-2078
Li, Jun; Li, Winnie Z.M.; Huang, Wen; Cheung, Wing Han; Bi, Wenchuan; Duan, Ran; Guo, A.J.Y.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Restricted localization of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase at the neuromuscular junctions - contribution and expression from motor neurons
FEBS JOURNAL, v. 276, (11), 2009, JUN, p. 3031-3042
Leung, Ka Wing; Xie, Heidi Qunhui; Chen, Vicky Ping; Mok, Mokka K.W.; Chu, Glanice K.Y.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines
Chinese Medicine, v. 4, 2009
Guo, Ava Jiang Yang; Choi, Roy Chi-Yan; Cheung, Anna Wing Han; Li, Jun; Chen, Ivy X.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Lau, B.W.C. Article
Transcriptional regulation of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in neuron: An inductive effect of neuron differentiation
Brain research, v. 1265, 2009, APR 10, p. 13-23
Xie, Heidi Qunhui; Choi, Roy Chi Yan; Leung, Ka Wing; Chen, Vicky Ping; Chu, Glanice K.Y.; Tsim, Karl Wah Keung Article
Two new compounds from the roots of Ligusticum chuanxiong
Journal of Asian natural products research, v. 11, (9), 2009, p. 805-810
Chang, Xin-Liang; Jiang, Zhi-Yong; Ma, Yun-Bao; Zhang, Xue-Mei; Tsim, Karl Wah Keung; Chen, Ji-Jun Article
A novel non-cholinergic function of acetylcholinesterase: osteogenic effect in cultured osteocarcoma MG-63 cells
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Sociey of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Guo, A.J.Y.; Zhu, Judy T T; Zheng, Ken Y Z; Bi, Wenchuan; Xie, Qunhui; Tsim, Karl Wah Keung Conference paper
Identification and characterization of splice variants of Proline Rich Membrane Anchor (PRiMA) of acetylcholinesterase (AChE) in different muscle fiber types in chicken
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Society of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Mok, Ka Wai; Chen, Ping; Chu, Kin Yan; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Quality control of ginseng by 1H NMR metabolic profiling
International Conference on Resource Development of Chinese Medicines from Northwestern China, Hong Kong, China, 2009
Chan, Pui Hei Nicholas; Choi, Chi Yan; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung; Lam, Henry H N Conference paper
The molecular assembly of acetylcholinesterase and butyrylcholinesterase: the formation of PRiMA-linked G4 hybrid
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Society of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Chen, Ping; Xie, Qunhui; Leung, Ka Wing; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
2008 15
A chinese herbal decoction prepared from radix astragali and radix angelicae sinensis induces the expression of erythropoietin in cultured Hep3B cells
Planta medica, v. 74, (4), 2008, MAR, p. 392-395
Gao, Qiu T.; Cheung, Jerry K.H.; Choi, Roy Chi Yan; Cheung, Anna Wing Han; Lv, Jun; Jiang, Zhi Y.; Duan, Ran; Zhao, Kui J.; Ding, An W.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Constitutive and agonist-induced dimerizations of the P2Y(1) receptor - Relationship to internalization and scaffolding
Journal of biological chemistry, v. 283, (16), 2008, APR 18, p. 11050-11063
Choi, Roy Chi Yan; Simon, Joseph; Tsim, Karl Wah Keung; Barnard, Eric A. Article
Myocyte enhancer factor 2 mediates acetylcholine-induced expression of acetylcholinesterase-associated collagen ColQ in cultured myotubes
MOLECULAR AND CELLULAR NEUROSCIENCE, v. 39, (3), October 2008, p. 429-438
Lau, Faye T.C.; Choi, Chi Yan; Xie, Qunhui; Leung, Ka Wing; Chen, Ping; Zhu, Judy T T; Bi, Weichuan; Chu, Glanice K.Y.; Tsim, Karl Wah Keung Article
Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity
Biochemical and biophysical research communications, v. 366, (3), 2008, FEB 15, p. 631-636
Fu, Hongjun; Li, Wenming; Luo, Jialie; Lee, Nelson T.K.; Li, Mingtao; Tsim, Karl Wah Keung; Pang, Yuanping; Youdim, Moussa B.H.; Han, Yifan Article
Regulation of PRiMA-linked G(4) AChE by a cAMP-dependent signaling pathway in cultured rat pheochromocyoma PC12 cells
Chemico-biological interactions, v. 175, (1-3, Sp. Iss. SI), 2008, SEP 25, p. 76-78
Choi, Roy Chi Yan; Mok, Mokka K.W.; Cheung, Anna Wing Han; Siow, Nina Lam; Xie, Heidi Qunhui; Tsim, Karl Wah Keung Article
Special Issue: Proceedings of the IXth International Meeting on Cholinesterases Preface
Chemico-biological interactions, v. 175, September 2008, p. 1-2
Doctor, Bhupendra P.; Tsim, Karl Wah Keung; Siow, Nina L. Article
The promoter activity of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in muscle: Suppressive roles of myogenesis and innervating nerve
Chemico-biological interactions, v. 175, (1-3, Sp. Iss. SI), 2008, SEP 25, p. 79-82
Xie, Heidi Qunhui; Leung, Ka Wing; Chen, Vicky Ping; Lau, Faye T.C.; Liu, Lois S.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Transcriptional Control of Different Subunits of AChE in Muscles: Signals Triggered by the Motor Nerve-derived Factors
Chemico-biological interactions, v. 175, (1-3), September 2008, p. 58-63
Tsim, Karl Wah Keung; Choi, Chi Yan; Xie, Qunhui; Zhu, Judy T T; Leung, Ka Wing; Lau, Faye T.C.; Chu, Glanice K.Y.; Chen, Ping; Mok, Mokka K.W.; Cheung, Wing Han; Bi, Weichuan Article
Anti-obesity effect of tectorigenin isolated from rhizoma belamcandae: regulation on apolipoprotein A-IV promoter in Caco2/TC7 enterocytes
The 3rd International Symposium on Functional Foods 2008 - Health Benefits of Plant Polyphenols, organized by PolyU, Hong Kong, 5 April 2008
Guo, Ava Jiangyang; Choi, Chi Yan; Li, Jun; Duan, Ran; Li, Winnie Z.M.; Cheung, J.K.H.; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung Conference paper
Development of new Chinese herbal decoction for anti-obesity
2008 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2008
Guo, Jiangyang; Huang, Wen; Duan, Ran; Li, Jun; Choi, Chi Yan; Dong, Tingxia; Lau, Brad W.C.; Tsim, Karl Wah Keung Conference paper
Localization of Proline-Rich Membrane Anchor (PRiMA)-associated acetylcholinesterase in vertebrate neuromuscular junctions
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, August 16-20, 2008, P17
Leung, Ka Wing; Xie, Qunhui; Bi, Wenchuan; Cheung, Ka Hei; Mok, Ka Wai; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Osteogenic effect of PRiMA-linked acetylcholinesterase in cultured MG-63 osteocarcoma cells
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, 16-20, August, 2008
Choi, Chi Yan; Zhu, Tingting; Xie, Qunhui; Chu, Kin Yan; Lau, Faye; Chen, Ping; Lin, Huangquan; Wan, David C.C.; Tsim, Karl Wah Keung Conference paper
Regulation of PRiMA-linked acetylcholinesterase in muscles, neurons and osteoblasts
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, 16-20 August, 2008
Tsim, Karl Wah Keung; Xie, Qunhui; Leung, Ka Wing; Zhu, Tingting; Chu, Kin Yan; Chen, Ping; Guo, Jiangyang; Choi, Chi Yan Conference paper
Studies on Dangui Buxue Tang: and example of Chinese herbal decoction flavonoids originated from Chinese Materia Medica (CMM): protect neurons against oxidative stress and beta-amyloid-induced cytotoxicity
2008 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six local universities, Hong Kong, 15 August 2008
Zhu, Tingting; Choi, Chi Yan; Cheung, Wing Han; Gao, Qiutao; Li, Jun; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Synergistic action of baicalein and daidzein in estrogenic and neuroprotective effects: development of potential health products and therapeutic drugs against alzheimer's disease
The 3rd International Symposium on Functional Foods 2008 - Health Benefits of Plant Polyphenols, organized by PolyU, Hong Kong, 5 April 2008
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Li, Jun; Li, Winnie Z.M.; Duan, Ran; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
2007 34
Calcitonin gene-related peptide induces the expression of acetylcholinesterase-associated collagen ColQ in muscle: a distinction in driving two different promoters between fast- and slow-twitch muscle fibers
Journal of neurochemistry, v. 102, (4), 2007, AUG, p. 1316-1328
Choi, Roy Chi Yan; Ting, Annie K.L.; Lau, Faye T.C.; Xie, Heidi Quihui; Leung, Ka Wing; Chen, Vicky Ping; Siow, Nina Lam; Tsim, Karl Wah Keung Article
Cloning and characterization of the yjeA gene, encoding a novel deoxyribonuclease, from Bacillus subtilis
Journal of Biochemistry, v. 142, (5), 2007, Nov, p. 647-654
Ng, Ka Lun; Lam, Chui Chi; Fu, Zhibiao; Han, Yi-Fan; Tsim, Karl Wah Keung; Wong, Wan Keung Article
Danggui Buxue Tang - A Chinese herbal decoction activates the phosphorylations of extracellular signal-regulated kinase and estrogen receptor alpha in cultured MCF-7 cells
FEBS letters, v. 581, (2), 2007, JAN 23, p. 233-240
Gao, Qiu T.; Choi, Roy Chi Yan; Cheung, Anna Wing Han; Zhu, Judy Ting Ting; Li, Jun; Chu, Glanice K.Y.; Duan, Ran; Cheung, Jerry K.H.; Jiang, Zhi Y.; Dong, Xiao B.; Zhao, Kui J.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Dang-Gui Buxue Tang protects against oxidant injury by enhancing cellular glutathione in H9c2 cells: Role of glutathione synthesis and regeneration
Planta medica, v. 73, (2), 2007, FEB, p. 134-141
Chiu, Po Yee; Leung, Hoi Yan; Siu, Ada H.Y.; Poon, Michel K.T.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Ko, Kam Ming Article
Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: A comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death
Journal of agricultural and food chemistry, v. 55, (6), 2007, MAR 21, p. 2438-2445
Zhu, Judy Ting Ting; Choi, Roy Chi Yan; Chu, Glanice K.Y.; Cheung, Wing Han; Gao, Qiu T.; Li, Jun; Jiang, Zhi Y.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
HPLC法测定远志中总皂苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2007, (09), 2007, p. 1329-1332
李军; 董晓兵; 姜勇; 董婷霞; 屠鹏飞; 詹华强 Article
Identification and quality control of Radix et Rhizoma Gentianae by chemical fingerprint: evaluation of gentiopicrin from different cultivated regions in China
Asian Journal of the Traditional Medicines, v. 1, (3-4), p. 1-9
Gao, Q.T.; Chou, G.X.; Dong, Tina Tingxia; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Tsim, Karl Wah Keung Article
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons
Journal of proteome research, v. 6, (7), 2007, p. 2435-2446
Fu, Hongjun; Li, Wenming; Liu, Yulin; Lao, Yuanzhi; Liu, Wei; Chen, Cheng; Yu, Hua; Lee, Nelson T.K.; Chang, Donald C.; Li, Peng; Pang, Yuanping; Tsim, Karl Wah Keung; Li, Mingtao; Han, Yifan Article
Regions in China identification and quality control of radix Codonopsis by chemical fingerprint: Evaluation of lobetyolin from different cultivated
Oriental Pharmacy and Experimental Medicine, v. 6, (4), 2006, p. 293-299
Chou, Gui X.; Gao, Qiu T.; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Chu, Glanice K.Y.; Jiang, Zhi Y.; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Regulation of a transcript encoding the proline-rich membrane anchor of globular muscle acetylcholinesterase - The suppressive roles of myogenesis and innervating nerves
Journal of biological chemistry, v. 282, (16), 2007, APR 20, p. 11765-11775
Xie, Heidi Qunhui; Choi, Roy Chi Yan; Leung, Ka Wing; Siow, Nina Lam; Kong, Ling W.; Lau, Faye T.C.; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung Article
Regulation of acetylcholinesterase expression by calcium signaling during calcium ionophore A23187-and thapsigargin-induced apoptosis
International journal of biochemistry & cell biology, v. 39, (1), 2007, p. 93-108
Zhu, Hui; Gao, Wei; Jiang, Hua; Jin, Qi-Huang; Shi, Yu-Fang; Tsim, Karl Wah Keung; Zhang, Xue-Jun Article
Simultaneous determination of phenols in Radix Polygalae by high performance liquid chromatography: Quality assurance of herbs from different regions and seasons
Journal of separation science, v. 30, (16), 2007, NOV, p. 2583-2589
Li, Jun; Dong, Xiaobing; Jiang, Yong; Gao, Qiutao; Jiang, Zhiyong; Cheung, Anna Wing Han; Duan, Ran; Dong, Tina Tingxia; Tu, Pengfei; Tsim, Karl Wah Keung Article
Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase
Molecular pharmacology, v. 71, (5), 2007, May, p. 1258-1267
Li, Wenming; Xue, Jian; Niu, Chunying; Fu, Hongjun; Lam, Colin S.C.; Luo, Jialie; Chan, Hugh H.N.; Xue, Huaiguo; Kan, Kelvin K.W.; Lee, Nelson Tsz Kin; Li, Chaoying; Pang, Yuanping; Li, Mingtao; Tsim, Karl Wah Keung; Jiang, Hualiang; Chen, Kaixian; Li, Xiaoyuan; Han, Yifan Article
Verification of the formulation and efficacy of Danggui Buxue Tang (a decoction of Radix Astragali and Radix Angelicae Sinensis): An exemplifying systematic approach to revealing the complexity of Chinese herbal medicine formulae
Chinese Medicine, v. 2, 2007
Gao, Qiutao; Li, Jun; Cheung, J.K.H.; Duan, Jinao; Ding, Anwei; Cheung, Anna Wing Han; Zhao, Kuijun; Li, Winnie Zhouming; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
测定天王补心丸和归脾丸中细叶远志皂苷的含量
中国中药杂志=China Journal of Chinese Materia Medica, v. 2007, (16), 2007, p. 1647-1649
董晓兵; 李军; 姜勇; 董婷霞; 屠鹏飞; 詹华强 Article
远志皂苷对照品细叶远志皂苷的制备
中药新药与临床药理=Traditional Chinese Drug Research and Clinical Plarmacology, v. 2007, (01), 2007, p. 53-54
董晓兵; 李军; 郑颖; 董婷霞; 詹华强 Article
A Chinese herbal decoction stimulates the expression of apolipoprotein A-IV in cultured enterocytes Caco 2 – TC7 cells: a possible drug for anti-obesity
2007 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six local universities, Hong Kong, 16 August 2007
Guo, A.J.Y.; Cheung, J.K.H.; Li, J.; Duan, Ran; Choi, Chi Yan; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung Conference paper
A Chinese Herbal decoction, Danggui Buxue Tang (DBT), stimulates the release of cytokines in cultured T-lymphocytes: A signal triggered by extracellular signal-regulated kinase
2007 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six loca universities, Hong Kong, 16 August 2007
Cheung, J.K.H.; Gao, Q.T.; Li, J.; Jiang, Z.Y.; Chu, G.K.Y.; Duan, Ran; Cheung, Wing Han; Zhao, K.J.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
A chinese herbal decoction, danggui buxue tang, activates extracellular signal-regulated kinase in cultured T-lymphocytes
FEBS letters, v. 581, (26), 2007, OCT 30, p. 5087-5093
Gao, Qiu T.; Cheung, Jerry K.H.; Li, Jun; Jiang, Zhi Y.; Chu, Glanice K.Y.; Duan, Ran; Cheung, Anna Wing Han; Zhao, Kul J.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Anti-obesity effect of a Chinese herbal decoction: Regulation of apolipoprotein A-IV expression and triglyceride formation
2007 TWGHs Eddie Wang Symposium on Integrated Chinese & Western Medicine, organized by Tung Wah Group of Hospitals & Hospital Authority, Hong Kong, 2 November 2007
Guo, A.J.Y.; Cheung, J.K.H.; Li, J.; Duan, Ran; Choi, Chi Yan; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung Conference paper
ATP induces acetylcholinesterase gene expression in cortical neurons: transduction and transcription control via P2Y1 receptors
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Siow, Nina Lam; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
Characterization of proline-rich membrane anchor (PRiMA)-associated acetylcholinesterase in cholinergic synapses
The IXth International Meeting on Cholinesterases, Suzhou, China
Leung, Ka Wing; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Cloning and characterization of acetylcholinesterase of green pufferfish tetraodon nigroviridis
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Lau, L.S.; Tung, E.; Lin, H.Q.; Tsim, Karl Wah Keung; Wan, D.C. Conference paper
Flavonoids derived from traditional Chinese medicine (TCM) in regulating the transcription of Acetylcholinesterase in osteosarcoma MG63 cells
2007 Hong Kong - Macau postgraduate symposium on Chinese medicine, Hong Kong,16 August 2007
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Xie, Qunhui; Ho, C.L.T.; Tsim, Karl Wah Keung Conference paper
Flavonoids derived from traditional chinese medicine (TCM) regulate the transcription of acetylcholinesterase in osteosarcoma MG63 cells
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Xie, Qunhui; Ho, C.L.T.; Tsim, Karl Wah Keung Conference paper
Flavonoids possess neuroprotective effects by preventing beta-amyloid-induced cell death on cultured neurons
2007 TWGHs Eddie Wang Symposium on Integrated Chinese & Western Medicine, organized by Tung Wah Group of Hospitals & Hospital Authority, Hong Kong, 2 November 2007
Zhu, J.T.; Chu, G.K.Y.; Dong, Ting Xia; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Li, W.; Fu, H.; Liu, Y.L.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Y. Conference paper
Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity
The IXth International Meeting on Cholinesterases, Suzhou, China
Fu, H.; Li, Wenming; Pi, R.B.; Luo, J.L.; Pang, Y.P.; Tsim, Karl Wah Keung; Han, Y. Conference paper
Regulation of a transcript encoding the proline-rich membrane anchor of globular muscle acetylcholinesterase: The suppressive roles of myogenesis and innervating nerves
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Leung, Ka Wing; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Regulation of different subunits of acetylcholinesterase expression during the nerve growth factor-induced neuronal differentiation in cultured PC12 cells
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Choi, Chi Yan; Mok, M.K.W.; Leung, Ka Wing; Siow, Lam; Tsim, Karl Wah Keung Conference paper
Stimulation of collagen-like subunit (ColQ) of acetylcholinesterase by muscular activity in muscle
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Lau, F.T.C.; Chen, Ping; Yim, J.C.H.; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
The expression of P2Y2, P2Y4 and P2Y6 receptors in cultured cortical neurons: signaling leads to acetylcholinesterases expression
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Chu, G.K.Y.; Siow, Lam; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
The motor nerve directs the oligomerization of collagen-tailed form acetylcholinesterase in muscles
The IXth International Meeting on Cholinesterases, Suzhou, China
Chen, Ping; Xie, Qunhui; Lau, F.T.C.; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Transcriptional control of different subunits of AChE in muscle: a regulation mediated by CAMP-dependent signaling cascades
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Tsim, Karl Wah Keung Conference paper
2006 48
A Chinese herbal decoction, Danggui Buxue Tang, prepared from Radix Astragali and Radix Angelicae Sinensis stimulates the immune responses
Planta Medica, v. 72, (13), 2006, Oct, p.1227-1231
Gao, Qiutao; Cheung, J.K.H.; Li, Jun; Chu, Glanice K.Y.; Duan, Ran; Cheung, Anna Wing Han; Zhao, Kuijun; Dong, T.T.X.; Tsim, Karl Wah Keung Article
A fructan, from radix ophiopogonis, stimulates the proliferation of cultured lymphocytes: Structural and functional analyses
Journal of natural products, v. 69, (9), 2006, SEP 22, p. 1257-1260
Wu, Xiangmei; Dai, Hui; Huang, Lixin; Gao, Xiaoming; Tsim, Karl Wah Keung; Tu, Pengfei Article
Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels
Journal of neurochemistry, v. 98, (5), 2006, SEP, p. 1400-1410
Fu, Hongjun; Li, Wenming; Lao, Yuanzhi; Luo, Jialie; Lee, Nelson T.K.; Kan, Kelvin K.W.; Tsang, Hing Wai; Tsim, Karl Wah Keung; Pang, Yuanping; Li, Zhiwang; Chang, Donald C.; Li, Mingtao; Han, Yifan Article
Chemical and biological assessment of a chinese herbal decoction containing radix astragali and radix angelicae sinensis: Determination of drug ratio in having optimized properties
Journal of agricultural and food chemistry, v. 54, (7), 2006, APR 5, p. 2767-2774
Dong, Tina Tingxia; Zhao, Kuijun; Gao, Qiutao; Ji, Zhaoning; Zhu, Ting T.; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Tsim, Karl Wah Keung Article
Chick acetylcholinesterase promoter regulation
Journal of molecular neuroscience, v. 30, (1-2), 2006, p. 33-34
Wan, David Chi Cheong; Zhang, Xiang; Siow, Nina L.; Xie, Heidi Qun Hui; Tsim, Karl Wah Keung Article
Dang-Gui Buxue Tang produces a more potent cardioprotective effect than its component herb extracts and enhances glutathione status in rat heart mitochondria and erythrocytes
Phytotherapy research, v. 20, (7), 2006, JUL, p. 561-567
Mak, Duncan Hon Fai; Chiu, Po Yee; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Ko, Kam Ming Article
Ginsenoside Re attenuate beta-amyloid and serum-free induced neurotoxicity in PC12 cells
Journal of ethnopharmacology, v. 107, (1), 2006, AUG 11, p. 48-52
Ji, Z.N.; Dong, Tina Ting Xia; Ye, W.C.; Choi, Roy Chi Yan; Lo, Chun Kit; Tsim, Karl Wah Keung Article
HPLC-ELSD Determination of Platycodin E in Radix Platcodonis of Different Sources
Chinese Journal of Pharmaceutical Analysis, 2006
Xia, Q.; Dong, Ting Xia; Tsim, Karl Wah Keung; Huang, Z.; Zhang, P. Article
HPLCELSD法测定不同来源桔梗中桔梗皂苷E的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2006, (05), 2006, p. 637-639
夏泉; 董婷霞; 詹华强; 黄赵刚; 张平 Article
Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia
Phytomedicine, v. 13, (6), 2006, Jun, p. 428-433
Li, Shaoping; Zhang, Guihong; Zeng, Qingshu; Huang, Zhaogang; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
ICP-MS法测定4种中药材中重金属含量
高等学校化学学报=China Journal of Chinese Materia Medica, v. 2007, (16）, 2007, p. 1314-1317
温慧敏; 陈晓辉; 董婷霞; 詹华强; 毕开顺 Article
In vitro estrogenic activity of formononetin by two bioassay systems
Gynecological endocrinology, v. 22, (10), 2006, OCT, p. 578-584
Ji, Zhao-Ning; Zhao, W.Y.; Liao, G.R.; Choi, Roy Chi Yan; Lo, Chun Keung; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine
NeuroReport, v. 17, (5), 2006, April, p. 471-474
Li, Wenming; Lee, Nelson Tsz Kin; Fu, Hongjun; Kan, Kelvin K.W.; Pang, Yuanping; Li, Mingtao; Tsim, Karl Wah Keung; Li, Xiaoyuan; Han, Yifan Article
Quality control of Cordyceps sinensis, a valued traditional Chinese medicine
Journal of pharmaceutical and biomedical analysis, v. 41, (5), 2006, Aug, p. 1571-1584
Li, Shaoping; Yang, Fengqing; Tsim, Karl Wah Keung Article
Simultaneous determination of 11 saponins in Panax notoginseng using HPLC-ELSD and pressurized liquid extraction
Journal of separation science, v. 29, (14), 2006, SEP, p. 2190-2196
Wan, Jian-Bo; Li, Peng; Li, Shaoping; Wang, Yitao; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung Article
Transcriptional control of different acetylcholinesterase subunits in formation and maintenance of vertebrate neuromuscular junctions
Journal of molecular neuroscience, v. 30, (1-2), 2006, p. 189-192
Tsim, Karl Wah Keung; Xie, Heidi Qun Hui; Ting, Annie; Siow, Nina L.; Ling, Karen K.Y.; Kong, Lingwei Article
固相萃取-毛细管气相色谱法测定党参、龙胆中15种有机氯农药的残留量
沈阳药科大学学报=Journal of Shenyang Pharmaceutical University, v. 2006, (12), 2006, p. 776-781
张潇潇; 陈晓辉; 董婷霞; 詹华强; 王晓东; 毕开顺 Article
莪术二酮对ADP诱导的兔血小板聚集的抑制作用
中国药理学通报=Chinese Pharmacological Bulletin, v. 2006, (09), 2006, p. 1151-1152
夏泉; 董婷霞; 詹华强; 梁嘉荣; 李绍平 Article
从西方思维看中药现代化
从西方思维看中药现代化 = Modernization of traditional Chinese medicine: a prospect from Western medicine / 孔宪铎, 詹华强着. 香港: 三联书店(香港)有限公司, 2006
Kung, Shain-Dow; Tsim, Karl Wah Keung Book
Quality Control of Cordyceps Sinensis, a Valued Traditional Chinese Medicine
/ Edited by J.N. Govil, V.K. Singh. Houston, Tex.: Studium Press LLC
Li, S.P.; Tsim, Karl Wah Keung Book chapter
A Chinese herbal decoction, Danggui Buxue Tang, prepared from Radix Astragali and Radix Angelicae Sinensis stimulates the immune responses
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Gao, Q.T.; Cheung, J.K.H.; Cheung, Wing Han; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Activation of P2Y1 receptor induces NR2A expression in cultured cortical neurons
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December , 2006
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
ATP Induces Post-Synaptic Specializations in Synapses: Transduction and Transcription control
Croucher Advanced Study Institution (ASI): Signaling in Cell Growth and Deifferentitaion, 16-20 Jan, 2006
Tsim, Karl Wah Keung Conference paper
Cordysinocan, a novel polysaccharide isolated from Cordyceps sinensis, stimulates the immune responses
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Cheung, J.K.H.; Cheung, Wing Han; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 Nanjing International Forum on Traditional Chinese Medicine, organized by Nanjing university of traditional chinese medicine and Administration of TCM of Jiangsu province, Nanjing, 4-6 November, 2006
Tsim, Karl Wah Keung Conference paper
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Tsim, Karl Wah Keung Conference paper
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 Shanghai Forum on International Standardization of Chinese Medicines and Herbal Products, organized by Shanghai University of Traditional Chinese Medicine and Shanghai R&D Center for Standardization of Chinese Medicine, Shanghai, 10 December, 2006
Tsim, Karl Wah Keung Conference paper
Determination of Tectoridin as Irisflorentin in Rhizoma Belamcandae
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Li, J.; Dong, X.B.; Gao, Q.T.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Fractionation of Anti-platelet Aggregation Activity From Roots of Panax notoginsen
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Jiang, Z.Y.; Li, S.P.; Duan, Ran; Chen, J.J.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Identification and characterization of flavonoids from traditional Chinese medicines-drug discovery for neruoprotection
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Zhu, J.T.T.; Chu, G.K.Y.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Identification and characterization of flavonoids from traditional Chinese medicines-Drug discovery for neuroprotection
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Zhu, Judy T T; Chu, G.K.Y.; Cheung, Wing Han; Choi, Chi Yan; Dong, Ting Xia; Li, J.; Gao, Q.T.; Jiang, Z.Y.; Tsim, Karl Wah Keung Conference paper
Identification and characterization of interacting partners of PRiMA, a membrane anchor of acetylcholinesterase-A proteomic approach
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Leung, Ka Wing; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Immuno-stimulating study on polysaccharide isolated from cultured Cordyceps
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Cheung, J.K.H.; Li, S.P.; Li, J.; Tsim, Karl Wah Keung Conference paper
Isolation of active compound responsible for the anti-platelet aggregation from Radix Notoginseng
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Jiang, Z.Y.; Duan, Ran; Chen, J.J.; Leung, D.H.F.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Probing the effects of Chinese Medicine Materials (CMM) in stimulating the apolipoprotein A-IV (Apo A-IV) expression in cultured enterocytes Caco-2 / TC7 cells
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Duan, R.R.; Chan, E.Y.Y.; Li, J.; Raymond, M.P.; Lau, B.W.C.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Quantitative Proteomic Analysis of the Neuroprotection of Bis(7)-Tacrine Against Glutamate-Induced Mitochondrial Dysfunction
36th Annual Meeting of the Society for Neuroscience, Georgia World Congress Center, Atlanta, Georgia (USA), 14-18 Oct 2006
Fu, H.; Li, W.; Liu, Y.; Lao, Y.; Lee, N.T.; Liu, W.; Li, K.C.; Pang, Y.; Chang, Donald C; Tsim, Karl Wah Keung; Li, M.; Han, Y. Conference paper
Radix Polygala protects PC12 cells from amyloid-beta peptide-induced neurotoxicity
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Li, J.; Chu, G.K.Y.; Dong, X.B.; Choi, Chi Yan; Lau, B.W.C.; Wong, Z.C.F.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Radix Polygala Protects PC12 Cells from Amyloid-Peptide-Induced Neurotoxicity
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Li, J.; Chu, G.K.Y.; Dong, X.B.; Choi, Chi Yan; Lau, B.W.C.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Regulation of acetylcholinesterase in neuron: The role of PRiMA in directing the formation of G4 AChE
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Choi, Chi Yan; Siow, Lam; Xie, Qunhui; Tsim, Karl Wah Keung Conference paper
Regulation of Collagen-like subunit (ColQ) of acetylcholinesterase by muscular activity in muscles
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Lau, F.T.C.; Chen, Ping; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Regulation of Transcript Encoding Proline-rich Membrane Anchor (PRiMA) of Globular form Acetylcholinesterase in Muscle: Suppressive Role of Myogenesis and Innervating Nerve
The 4th Congress of Federation of Asian and Oceanian Neuroscience Societies (FAONS), Hong Kong. 30 November - 2 December, 2006
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Leung, Ka Wing; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Specific estrogenic and immune regulatory effects of Danggui Buxue Tang-a traditional Chinaese herbal decoction prepared from Radix Angelicae Sinensis and Radix Astragali
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Gao, Q.T.; Cheung, J.K.H.; Cheung, Wing Han; Jiang, Z.Y.; Li, J.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Synergistic Neuroprotection by BIS(7)-Tacrine Via Moderate Blockade of N-Methyl-D-Aspartate Receptors and Selective Inhibition of Neuronal Nitric Oxide Synthase
36th Annual Meeting of the Society for Neuroscience, Georgia World Congress Center, Atlanta, Georgia (USA), 14-18 Oct 2006
Li, W.; Xue, J.; Niu, C.; Fu, H.; Lam, C.S.; Lee, N.T.; Pang, Y.; Li, M.; Jiang, H.; Chen, K.; Tsim, Karl Wah Keung; Li, X.; Han, Y. Conference paper
The Effects of Zhikang Granules in stimulating the Apolipoprotein A-IV (Apo A-IV) Expression in Cultured Enterocytes Caco-2 / TC7 cells
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Dong, Ting Xia; Duan, Ran; Chan, E.Y.Y.; Li, J.; Tsim, Karl Wah Keung Conference paper
The expression and functional role of P2Y2, P2Y4 and P2Y6 receptors in cultured cortical neurons
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Chu, G.K.Y.; Siow, Lam; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
The motor nerve directs the oligomerization of collagen-tailed form acetylcholinesterase in muscles
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Chen, Ping; Xie, Qunhui; Lau, F.T.C.; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
The Preparation of Tenuifolin as Chemical Market of Radix Polygalae
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Dong, X.B.; Li, J.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Traditional Chinese medicines reduce triglyceride accumulation in cultured adipocyte (3T3-L1 cells)
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Guo, A.J.Y.; Chu, G.K.Y.; Ho, C.L.T.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
2005 37
A DNA microarray for the authentication of toxic traditional Chinese medicinal plants
Planta Medica, v. 71, (6), June 2005, p. 580-584
Carles, Maria C.; Cheung, Kin Lok; Moganti, Shanti; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu; Sucher, Nikolaus J. Article
An arabinogalactan isolated from the stems of Cistanche deserticola induces the proliferation of cultured lymphocytes
International journal of biological macromolecules, v. 37, (5), 2005, Dec, p. 278-282
Wu, Xiangmei; Gao, Xiaoming; Tsim, Karl Wah Keung; Tu, Pengfei Article
ATP induces the post-synaptic gene expression in neuron-neuron synapses: Transcriptional regulation of AChE catalytic subunit
Chemico-biological interactions, December 15, 2005, 157-158:423-426
Siow, Nina L.; Xie, Heidi Q.; Choi, Roy C.Y.; Tsim, Karl Wah Keung Article
ATP potentiates the formation of AChR aggregate in the co-culture of NG108-15 cells with C2C12 myotubes
FEBS letters, v. 579, (11), 2005, APR 25, p. 2469-2474
Ling, KKY; Siow, Nina Lam; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Authentication and quality control of Cordyceps sinensis, a traditional Chinese medicine known as summer-grass winter-worm
Oriental Pharmacy and Experimental Medicine, v.5, (4), p.262-271
Cheung, Jerry K.H.; Li, Shaoping; Tsim, Karl Wah Keung Article
Danggui Buxue Tang (Chinese Angelica Decoction): A Sample Trial in TCM Standardization
Asia-Pacific Biotech News (APBN), v. 8, (23), 2004, Dec, p. 1316-1321
Tsim, Karl Wah Keung Article
Identificaiton of Stellaria medica by PCR
Journal of Chinese Pharmaceutical Sciences, v. 14, (3), 2005, p. 144-148
Huang, Wenzhe; Dong, Tina Tingxia; Qi, Huanyang; Lu, Zhenqiang; Tsim, Karl Wah Keung Article
Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry
Journal of pharmaceutical and biomedical analysis, v. 39, (3-4), 2005, SEP 15, p. 552-558
Yang, Fengqing; Li, Shaoping; Chen, Ying; Lao, Sincheng; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Molecular Genetic and Chemical Assessment of Rhizoma Curcumae in China
Journal of agricultural and food chemistry, v. 53, (15), 2005, Jul, p. 6019-6026
Xia, Quan; Zhao, Kuijun; Huang, Zhaogang; Zhang, Ping; Dong, Ting Xia; Li, Shaoping; Tsim, Karl Wah Keung Article
Novel dimeric acetylcholinesterase inhibitor bis(7)-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors
Journal of biological chemistry, v. 280, (18), 2005, MAY 6, p. 18179-18188
Li, Wenming; Pi, Rongbiao; Chan, Hugh H.N.; Fu, Hongjun; Lee, Nelson; Tsang, HingWai; Pu, Yongmei; Chang, Donald; Li, Chaoying; Luo, Jialie; Xiong, Keming; Li, Zhiwang; Xue, Hong; Carlier, Paul R.; Pang, Yuan-Ping; Tsim, Karl Wah Keung; Li, Mingtao; Han, Yifan Article
Orthogonal array design in optimizing the extraction efficiency of active constituents from roots of Panax notoginseng
Phytotherapy research, v. 19, (8), 2005, Aug, p. 684-688
Dong, Tina Tingxia; Zhao, Kuijun; Huang, W.Z.; Leung, Kawing; Tsim, Karl Wah Keung Article
Quantitative detection of gentiopicrin in Radix Gentianae
Shanghai Journal of Traditional Chinese medicine, v. 39, p.53-55
Chou, G.X.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wang, Z.T.; Yu, Z.L. Article
Regulation of PRiMA: membrane anchor of acetylcholinesterase (AChE) in neuron and muscle
Chemico-biological interactions, 2005, Dec, p. 157-158
Xie, Heidi Q.; Siow, Nina L.; Peng, H. Benjamin; Massoulié, Jean; Tsim, Karl Wah Keung Article
Species identification of Dyers woad leaf by DNA sequences of 5S-rRNA spacer domain and random amplified polymorphic DNA (RAPD)
Oriental Pharmacy and Experimental Medicine, v. 5, (2), p. 117-123
Zhao, K.J.; Dong, Tina Tingxia; Wong, Y.C.; Tu, P.F.; Tsim, Karl Wah Keung Article
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ in fast- and slow-twitch muscle fibers
Chemico-biological interactions, v. 157, (Sp. Iss. SI), 2005, DEC 15, p. 63-70
Ting, Annie; Siow, Nina L.; Kong, Lingwei; Tsim, Karl Wah Keung Article
三七中三七素的含量测定
中国药学杂志=Chinese Pharmaceutical Journal, v. 2005, 13, 2005, p. 1017-1019
崔秀明; 徐珞珊; 王强; 陈中坚; 董婷霞; 詹华强 Article
不同来源莪术中莪术醇、吉马酮、莪术二酮GC-MS定量分析
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2005, (07), 2005, p. 827-830
杨丰庆; 李绍平; 陈莹; 刘倩青; 王一涛; 董婷霞; 詹华强 Article
(43) ATP induces the post-synaptic gene expression in neuron-neuron synapses: Transcriptional regulation of AChE catalytic subunit
Chemico-Biological Interactions, v. 157, 2005, p. 423-426
Siow, Nina Lam; Xie, Heidi Qunhui; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
(48) Regulation of PRiMA: Membrane anchor of acetylcholinesterase (AChE) in neuron and muscle
Chemico-Biological Interactions, v. 157, 2005, p. 432
Xie, Qunhui; Siow, Lam; Peng, Benjamin H; Massoulié, J.; Tsim, Karl Wah Keung Conference paper
A cAMP-dependent Signaling Directs the Post-Synaptic Expression of ColQ, a Subunit of Collagen-Tailed form AChE, at the Vertebrate Neuromuscular Junctions.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Ting, A.K.L.; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
A Flavonol Glycoside, Isolated from Roots of Panax Notoginseng, Protects the Beta-Amyloid-Induced Neurotoxicity in Cultured PC12 Cells
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Zhu, Judy T T; Leung, Ka Wing; Cheung, J.K.H.; Zhao, K.J.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
ATP induces post-synaptic gene expression in neuron-neuron synapses: the transcription regulation of NR2A subunit.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
Calcitonin gene-related peptide mediates synaptic expression of collagen-like subunit (COLQ) of acetylcholinesterase in muscle
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Ting, A.K.L.; Choi, Chi Yan; Lau, F.T.C.; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Characterization of chick AChE promoter: responses to nerve-derived factors
The 12th International Symposium on Cholinergic Mechanisms in Alicante, Spain, October 1-5, 2005
Wan, D.C.C.; Zhang, X.; Siow, Lam; Xie, H.Q.H.; Tsim, Karl Wah Keung Conference paper
Functional roles of P2Y1 receptor in cultured cortical neurons: regulation of AChE expression and small GTPase activation
Neuroscience 2005 in Washington, D.C., 12-16 Nov 2005
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
Identification of Critical Early Genes Involved in Nerve Growth Factor-Induced PC12 Differentiation
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5 - 6 December 2005
Xiao, Fang; Ng, Yu Pong; Tsim, Karl Wah Keung; Wise, Helen; Wong, Yung Hou; Ip, Nancy Yuk-Yu; Wu, Zhenguo Conference paper
NGF-Induced Neuronal Differentiation of PC12 Cells: Delineation of Signaling Molecules and Mapping of Pathways.
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5 - 6 December 2005
Leung, W.K.W.; Choi, Chi Yan; Ip, Nancy Yuk-Yu; Wu, Zhenguo; Wong, Yung Hou; Cheung, P.T.; Tsim, Karl Wah Keung Conference paper
Novel Dimeric Acetylcholinesterase Inhibitor Bis ( 7 ) - Tacrine Exerts Multiple Neuroprotective Activities by Inhibiting Nitric Oxide Synthase
35th Annual Meeting of the Society for Neuroscience, Washington Convention Center, Washington, DC (USA), 12-16 Nov 2005
Li, W.; Chan, H.H.N.; Xue, J.; Xue, Hong; Kan, K.K.W.; Zhao, Y.; Lee, N.T.K.; Luo, J.; Li, Z.; Carlier, P.R.; Pang, Y.; Tsim, Karl Wah Keung; Li, M.; Li, X.; Han, Yilong Conference paper
Regulation of collagen-like subunit (COLQ) of acetylcholinesterase by muscular activity in muscle
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Lau, F.T.C.; Ting, A.K.L.; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Regulation of NR2A, a subunit of N-methyl-d-aspartate receptor, by a cAMP-dependent signaling pathway in neuronal cultures
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Siow, Lam; Choi, Chi Yan; Xie, Qunhui; Tsim, Karl Wah Keung Conference paper
Regulation of P2Y1 Receptor: Signal Transduction, Dimerization, Desensitization and Internalization
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Choi, Chi Yan; Wong, Cecilia S.S.; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
Restricted Localization of P2Y1 Receptor in Cortical Neurons: Functional Role in Small GTPase Activation.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Ling, K.Y.; Kong, L.W.; Tsim, Karl Wah Keung Conference paper
Role of Calmodulin-Dependent Kinase II in Nerve Growth Factor-Induced Differentiation of PC12 Cells.
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5-6 December 2005
Kam, Yuet Fong; Yung, Ying; Wu, Eddy H.T.; Ng, Yu Pong; Wu, Zhenguo; Tsim, Karl Wah Keung; Wise, Helen; Ip, Nancy Yuk-Yu; Wong, Yung Hou Conference paper
Role of PRiMA in Regulating Globular Form of Acetylcholinesterase: The Possible Role of Ache Oligomeriztion
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
The expression and localization of PRiMA, a membrane anchor of acetylcholinesterase, during neuron and muscle differentiation
Neuroscience 2005 in Washington, D.C., 12-16 Nov 2005
Xie, Qunhui; Siow, Lam; Ting, A.K.L.; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Transcriptional control of different subunits of acetylcholinesterase in the formation and maintenance of vertebrate neuromuscular junctions
The 12th International Symposium on Cholinergic Mechanisms in Alicante, Spain, October 1-5, 2005
Tsim, Karl Wah Keung; Xie, Qunhui; Ting, A.K.L.; Siow, Lam; Lau, F.; Kong, L. Conference paper
Transcriptional regulation of PRiMA, a membrane anchor of globular form AChE, in neuron and muscle differentiation.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Xie, Qunhui; Siow, Lam; Ting, A.K.L.; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
2004 19
ATP potentiates agrin-induced AChR aggregation in cultured myotubes - Activation of RhoA in P2Y1 nucleotide receptor signaling at vertebrate neuromuscular junctions
Journal of biological chemistry, v. 279, (30), 2004, JUL 23, p. 31081-31088
Ling, KKY; Siow, Nina Lam; Choi, Roy Chi Yan; Ting, AKL; Kong, LW; Tsim, Karl Wah Keung Article
Chemical and biological assessment of a traditional Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis: Orthogonal array design to optimize the extraction of chemical constituents
Planta medica, v. 70, (12), 2004, DEC, p. 1222-1227
Song, Zong H.; Ji, Zhaoning; Lo, Chunkeung; Dong, Tina Tingxia; Zhao, Kuijun; Ll, O.T.W.; Haines, Christopher John; Kung, Shain D.; Tsim, Karl Wah Keung Article
Distinction of water-soluble constituents between natural and cultured Cordyceps by capillary electrophoresis
Phytomedicine, v. 11, (7-8), 2004, NOV, p. 684-690
Li, Shaoping; Song, Zong H.; Dong, Tina Tingxia; Ji, Zhaoning; Lo, Chunkeung; Zhu, Shangquan; Tsim, Karl Wah Keung Article
Identification and quantification of 13 components in Angelica sinensis (Danggui) by gas chromatography-mass spectrometry coupled with pressurized liquid extraction
Analytica Chimica Acta, v. 526, (2), 2004, Nov, p. 131-137
Lao, Sincheng; Li, Shaoping; Kan, Kelvin K.W.; Li, Peng; Wan, Jianbo; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
P2Y(2) receptor activation regulates the expression of acetylcholinesterase and acetylcholine receptor genes at vertebrate neuromuscular junctions
Molecular pharmacology, v. 66, (4), 2004, OCT, p. 794-806
Tung, EKK; Choi, Roy Chi Yan; Siow, Nina Lam; Jiang, JXS; Ling, KKY; Simon, J.; Barnard, EA; Tsim, Karl Wah Keung Article
Simultaneous determination of ergosterol, nucleosides and their bases from natural and cultured Cordyceps by pressurised liquid extraction and high-performance liquid chromatography
Journal of chromatography A, v. 1036, (2), 2004, May, p. 239-243
Li, Shaoping; Li, Peng; Lai, C.M.; Gong, Yuanxiang; Kan, Kelvin K.W.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wang, Yitao Article
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ - Differential expression in fast and slow twitch muscle fibers is driven by distinct promoters
Journal of biological chemistry, v. 279, (26), 2004, Jun, p. 27098-27107
Lee, Henry H.C.; Choi, Roy Chi Yan; Ting, Annie; Siow, Nina Lam; Jiang, Joy; Massoulié, Jean M.; Tsim, Karl Wah Keung Article
A formula of TCM: Danggui Buxe Tang
Takungpao, 19 February
Tsim, Karl Wah Keung Book
Modernization of Traditional Chinese Medicine: Problems in Safety and Quality Assurance
Vision of 2050: Agriculture in China / Edited by Tso et al. New York
Tsim, Karl Wah Keung; Kung, Shain-Dow Book chapter
The Biological and Pharmacological Properties of Cordyceps Sinensis, a Traditional Chinese medicine, that has Broad Clinical Applications
In: Herbal Medicines: Molecular Basis of Biological Activity and Health; Packer et al ed. Marcel Dekker Inc. New York / p. 657-682
Li, S.P.; Tsim, Karl Wah Keung Book chapter
The Role of P2Y1 Nucleotide Receptors in the Formation and Maintenance of the Skeletal Neuromuscular Junctions
Cholinergic Mechanisms / p. 105-110
Tsim, Karl Wah Keung; Choi, Chi Yan; Siow, Lam; Cheng, Anthony W.M.; Ling, Karen K Y; Tung, E.K.K.; Kong, L.W.; Barnard, E.A. Book chapter
Activation of P2Y1 Receptor Induces the Expression of AChE via MAP Kinase Signalling Pathway in Cultured Cortical Neurons
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 84
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
ATP Induces the Post-Synaptic Gene Expression in Neuron-Neuron Synapses: the Promoter Analysis of AChE Catalytic Subunit.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
ATP-Activated Rho A GTPase Modulate Agrin-Induced AChR Aggregation
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 85
Ling, K.K.Y.; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
PriMA, the Membrane Anchor of Acetylcholinesterase in the Brain: Characterization and Function
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 85
Xie, Qunhui; Genin, A.; Choi, Chi Yan; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Regulation of PRiMA, the Membrane Anchor of of Acetylcholiesterase, During Neuron and Muscle Differentiation.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Xie, Qunhui; Siow, Lam; Ting, A.K. L.,; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Transcription Regulation of Collagen-Tailed Subunit of Acetylcholinesterase in Muscle
6th APSN meeting in Hong Kong, J. Neurochem, v. 88, (suppl), p. 85
Ting, A.K.L.; Lee, H.H.C.; Choi, Chi Yan; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Transcriptional Regulation of AChE-Associated Collagen ColQ: Differential Expression in Fast-and Slow-Twitch Muscle Fibers is Driven by Distinct Promoters.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Tsim, Karl Wah Keung Conference paper
Two Distinct Promoters of AChE Gene in Chicken are Responsible for Tissue-Specific Expression of Different Transcripts
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 38
Tung, E.K.K.; Zhang, X.; Choi, Chi Yan; Tsim, Karl Wah Keung; Wan, D.C.C. Conference paper
2003 17
A polysaccharide isolated from Cordyceps sinensis, a traditional Chinese medicine, protects PC12 cells against hydrogen peroxide-induced injury
Life sciences, v. 73, (19), 2003, SEP 26, p. 2503-2513
Li, Shaoping; Zhao, Kuijun; Ji, Zhaoning; Song, Zong H.; Dong, Tina Tingxia; Lo, Chunkeung; Cheung, J.K.H.; Zhu, Shangquan; Tsim, Karl Wah Keung Article
ATP acts via P2Y(1) receptors to stimulate acetylcholinesterase and acetylcholine receptor expression: Transduction and transcription control
JOURNAL OF NEUROSCIENCE, v. 23, (11), 2003, JUN 1, p. 4445-4456
Choi, Roy Chi Yan; Siow, Nina Lam; Cheng, Anthony WM; Ling, Karen KY; Tung, EKK; Simon, J.; Barnard, EA; Tsim, Karl Wah Keung Article
ATP induces post-synaptic gene expressions in vertebrate skeletal neuromuscular junctions
Journal of neurocytology, v. 32, (5-8), 2003, JUN-SEP, p. 603-617
Tsim, Karl Wah Keung; Choi, Roy Chi Yan; Siow, Nina Lam; Cheng, AWM; Ling, KKY; Jiang, JXS; Tung, EKK; Lee, HHC; Xie, Heidi Qunhui; Simon, J.; Barnard, EA Article
Authentication of Panax notoginseng by 5S-rRNA spacer domain and random amplified polymorphic DNA (RAPD) analysis
Planta medica, v. 69, (6), 2003, Jun, p. 584-586
Cui, Xiuming; Lo, Chunkeung; Yip, K.L.; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
CDNA encodes Xenopus P2Y(1) nucleotide receptor: expression at the neuromuscular junctions
NeuroReport, v. 14, (3), 2003, MAR 3, p. 351-357
Cheng, Anthony WM; Kong, LW; Tung, EKK; Siow, Nina Lam; Choi, Roy Chi Yan; Zhu, SQ; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung Article
Characterization of a rhamnogalacturonan and a xyloglucan from Nerium indicum and their activities on PC12 pheochromocytoma cells
Journal of natural products, v. 66, (1), 2003, Jan, p. 7-10
Ding, Kan; Fang, Jinian; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wu, Houming Article
Chemical assessment of roots of Panax notoginseng in China: Regional and seasonal variations in its active constituents
Journal of agricultural and food chemistry, v. 51, (16), 2003, Jul, p. 4617-4623
Dong, Tina Tingxia; Cui, Xiuming; Song, Zong H.; Zhao, Kuijun; Ji, Zhaoning; Lo, Chunkeung; Tsim, Karl Wah Keung Article
Genetic distinction of Radix Adenophorae from its adulterants by the DNA sequence of 5S-rRNA spacer domains
American Journal of Chinese Medicine, v. 31, (6), 2003, p. 919-926
Zhao, Kuijun; Dong, Tina Tingxia; Cui, Xiuming; Tu, Pengfei; Tsim, Karl Wah Keung Article
Molecular genetic and chemical assessment of radix angelica (Danggui) in China
Journal of agricultural and food chemistry, v. 51, (9), 2003, Apr, p. 2576-2583
Zhao, Kuijun; Dong, Tina Tingxia; Tu, Pengfei; Song, Zong H.; Lo, Chunkeung; Tsim, Karl Wah Keung Article
Muscle induces neuronal expression of acetylcholinesterase in neuron-muscle co-culture - Transcriptional regulation mediated by camp-dependent signaling
Journal of biological chemistry, v. 278, (46), 2003, NOV 14, p. 45435-45444
Jiang, JXS; Choi, Roy Chi Yan; Siow, Nina Lam; Lee, HHC; Wan, DCC; Tsim, Karl Wah Keung Article
Phylogeny of Astragalus in China: Molecular evidence from the DNA sequences of 5S rRNA spacer, ITS, and 18S rRNA
Journal of agricultural and food chemistry, v. 51, (23), 2003, Nov, p. 6709-6714
Dong, Tina Tingxia; Ma, Xiaoqiang; Clarke, Clarles; Song, Zong H.; Ji, Zhaoning; Lo, Chunkeung; Tsim, Karl Wah Keung Article
Signalling pathways and ion channel regulations of P2Y receptors
Drug development research, v. 59, (1), 2003, MAY, p. 36-48
Barnard, Eric A.; Simon, Joseph; Tsim, Karl Wah Keung; Filippov, Alexander K.; Brown, David A. Article
建立评价当归质量的HPLC指纹图谱分析方法
中国药学杂志=Chinese Pharmaceutical Journal, v. 2003, (10), 2003
刘荣霞; 周婷婷; 董婷霞; 詹华强; 毕开顺 Article
Bis(7)-tacrine Attenuates Glutamate-Induced Apoptosis in Rat Cerebellar Granule Neurons by Regulating Calcium Homeostasis
Society for Neuroscience, 33rd Annual Meeting, New Orleans, LA, USA
Li, Wenming; Pi, Rongbiao; Chan, H.H.N.; Lee, N.T.K.; Tsang, H.W.; Pu, Y.M.; Wang, W.Y.; Chan, J.L.N.; Leung, W.C.; Xue, Hong; Chang, Donald C; Sucher, Nikolaus J.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Y. Conference paper
Prevention of b-amyloid-induced Neurotoxicity in Cultured PC12 Cells by Ginsenoside and Favonoid Isolated from Roots of Panax Notoginseng
11th Euroconferecne on Aptoptosis in Ghent, Belgium
Wan, D.C.C.; Ji, Z.N.; Song, Z.H.; Lo, Chun Keung; Cheung, J.K.H.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
PRiMA, the Membrane Anchor of Acetylcholinesterase in the Brain: Searching for its Proteic Partners Using the Yeast-two hybrid system
The 23rd Annual Scientifc Meeting, The Hong Kong Society of Neurosciences, Hong Kong, PP4, 9-10 December
Xie, Qunhui; Genin, Alexis; Choi, Chi Yan; Peng, Benjamin H; Massoulie, Jean; Tsim, Karl Wah Keung Conference paper
Transcriptional Regulation of Collagen-Tailed Subunit (ColQ) of Acetylcholinesterase (AChE) in Muscle
The 23rd Annual Conference of The Hong Kong Society of Neurosciences
Ting, A.K.L.; Lee, H.H.C.; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
2002 21
A cyclic AMP-dependent pathway regulates the expression of acetylcholinesterase during myogenic differentiation of C2C12 cells
Journal of biological chemistry, v. 277, (39), 2002, SEP 27, p. 36129-36136
Siow, Nina Lam; Choi, Roy Chi Yan; Cheng, Anthony WM; Jiang, JXS; Wan, DCC; Zhu, SQ; Tsim, Karl Wah Keung Article
Chemical analysis of Radix Astragali (Huangqi) in China: A Comparison with its Adulterants and Seasonal Variations
Journal of agricultural and food chemistry, v. 50, (17), 2002, Aug, p. 4861-4866
Ma, Xia Q.; Shi, Q.; Duan, Jinao; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Determination of flavonoids in Pana notoginseng
Chinese Traditional and Herbal Drugs, v. 33, (7), p. 611-612
Cui, Xiu M.; Dong, Tina Tingxia; Huang, Wen Z.; Chen, Zhong J.; Tsim, Karl Wah Keung Article
Identification on Panax notoginseng and its adulterants by HPLC fingerprint chromatogram
Chin. Trad. and Herb. Drugs, v. 33, (10), p. 941-943
Cui, Xiu M.; Dong, Tina Tingxia; Chen, Zhong J.; Tsim, Karl Wah Keung Article
The development of TCM formula and patent drugs
Traditional Chinese Drug Research and Clinical Pharmacology, v. 13, (6), p. 343-345
Su, Ziren; Huang, Xiao D.; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The fruiting body and its caterpillar host of Cordyceps sinensis show close resemblance in main constituents and anti-oxidation activity
Phytomedicine, v. 9, (4), 2002, MAY, p. 319-324
Li, Shaoping; Su, Ziren; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The heat-induced degradation of magnolol and honokiol in supercritical fluid CO2 extraction from Magnolia bark
Yaoxue Xuebao, v. 37, (11), 2002, Nov, p. 870-875
Su, Ziren; Dong, Tina Tingxia; Lo, Chunkeung; Tsim, Karl Wah Keung Article
The signaling pathways mediated by P2Y nucleotide receptors in the formation and maintenance of the skeletal neuromuscular junction
NeuroSignals, v. 11, (1), 2002, JAN-FEB, p. 58-64
Tsim, Karl Wah Keung; Barnard, Eric A. Article
三七中黄酮成分的含量测定
中草药=Chinese Traditional and Herbal Drugs, v. 2002, (07), 2002
崔秀明; 董婷霞; 黄文哲; 陈中坚; 詹华强 Article
三七及其混淆品的HPLC指纹图谱鉴定
中草药=Chinese Traditional and Herbal Drugs, v. 2002, (10), 2002
崔秀明; 董婷霞; 陈中坚; 詹华强 Article
三七多糖成分的含量测定及其变化
中国药学杂志=Chinese Pharmaceutical Journal, v. 2002, (11), 2002
崔秀明; 董婷霞; 陈中坚; 王朝梁; 詹华强 Article
高温致厚朴SFE－CO2萃取物中厚朴酚、和厚朴酚降解
药学学报=Acta Pharmaceutica Sinica, v. 2002, (11), 2002, p. 870-875
苏子仁; 董婷霞; 卢振强; 詹华强 Article
Apoptosis in Rat Cerebellar Granule Neurons
Society for Neuroscience, 32nd Annual Meeting, Orlando, Florida
Li, Wenming; Chan, Hiu Nam; Lee, Tsz Kin Nelson; Xie, Y.B.; Ho, Chi Ming; Carlier, P.R.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Yi Fan Conference paper
ATP, Mediated by Rho A GTPase, Potentiates the Agrin-Induced AChR Aggregation in Cultured Chick Myotubes
22nd Annual Conference of The Hong Kong Society of Neurosciences
Ling, Karen K Y; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Expression and Localization of Different P2Y Receptors in Cultured Cortical Neurons
22nd Annual Conference of The Hong Kong Society of Neurosciences
Siow, Lam; Choi, Chi Yan; Barnard, Eric A.; Tsim, Karl Wah Keung Conference paper
Functional Roles of P2Y2 and P2Y4 Nucleotide Receptors in the Formation and Maintenance of the Neuromuscular Junctions
22nd Annual Conference of The Hong Kong Society of Neurosciences
Tung, Edmund K.K.; Choi, Chi Yan; Siow, Lam; Barnard, Eric A.; Tsim, Karl Wah Keung Conference paper
Huperzine A, a Promising Anti-Alzheimer's Agent, Reduces Staurosporine-Induced Apoptosis in NG108-15 Cells
XIth International symposium on cholinergic mechanisms-function and dysfunction & 2nd misrahi symposium on neurobiology, 5-9 May, St. Moritz, Switzerland
Han, Yi Fan; Xiao, Xiao-Qiu; Wu, Dong-Cheng; Gao, Yang; Ho, Wing-Lok; Lee, Tze-Kin Nelson; Fu, Yan; Tsim, Karl Wah Keung Conference paper
PriMA, the Membrane Anchor of AChE in the Brain: Searching for its Proteic Partners Using the Yeast-Two Hybrid System
22nd Annual Conference of The Hong Kong Society of Neurosciences
Xie, Qui H.; Genin, Alexis; Peng, Benjamin H; Massoulie, Jean; Tsim, Karl Wah Keung Conference paper
Regulation of Neuronal AChE Expression by Muscle in Neuron-Muscle Co-Cultures
22nd Annual Conference of The Hong Kong Society of Neurosciences
Jiang, Joy X.S.; Tsim, Karl Wah Keung Conference paper
The Transcriptional Regulation of Collagen-Tailed (ColQ), a Subunit of Asymmetric Acetylcholinesterase is Muscle Fibre-Type-Specific Dependent
22nd Annual Conference of The Hong Kong Society of Neurosciences
Lee, Henry H.C.; Genin, Alexis; Tsim, Karl Wah Keung Conference paper
Two Alternative Promoters for Chicken Acetylcholinesterase Gene and Tissue-Specific Transcription
22nd Annual Conference of The Hong Kong Society of Neurosciences
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C. Conference paper
2001 22
Advance of Anti-tumor for Cordyceps sinensis
Chinese Traditional & Herbal Drugs, v. 32, p. 373-375
Li, Shao Ping; Ji, Hui; Li, Ping; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Li, Wen Qi Article
Anti-oxidation activity of different types of natural Cordyceps sinensis and cultured Cordyceps mycelia
Phytomedicine, v. 8, (3), 2001, May, p. 207-212
Li, Shao Ping; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Authentic Identification of Stigma Croci (Stigma of Crocus sativus) from its Adulterants by Molecular Genetic Analysis
Planta medica, v. 67, (2), 2001, Mar, p. 183-186
Ma, Xia Q.; Zhu, Dayuan; Li, Shao Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction
Nature Neuroscience, v. 4, (4), April 2001, p. 374-381
Fu, Amy Kit Yu; Fu, Wing Yu; Cheung, Janet; Tsim, Karl Wah Keung; Ip, Fanny Chun Fun; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu Article
Chips and Qi: Microcomponent-Based Analysis in Traditional Chinese Medicine
Fresenius Journal of Analytical Chemistry, v. 371, (2), September 2001, p. 190-194
Carles, Maria; Lee, Ming Hung Thomas; Moganti, Shanti; Lenigk, Ralf; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu; Hsing, I-Ming; Sucher, Nikolaus J. Article
Comments on the change of drug nature and innovation of Chinese patent drugs in the preparing process
Traditional Chinese Drug Research and Clinical Pharmacology, v. 13, p. 1-4
Su, Ziren; Chen, Jiannan; Shen, Xiaoling; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Determination of nucleosides in natural Cordyceps sinensis and cultured Cordyceps mycelia by capillary electrophoresis
Electrophoresis, v. 22, (1), 2001, p. 144-150
Li, Shao Ping; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Determination of water-soluble constituents from the drug materials of 'Honghua'
Journal of Pharmaceutical Practice, v. 18, p. 310-311
Ma, Xiaoqing; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Expression of the P2Y1 nucleotide receptor in chick muscle: Its functional role in the regulation of acetylcholinesterase and acetylcholine receptor
Journal of Neuroscience, v. 21, (23), December 2001, p. 9224-9234
Choi, Roy Chi Yan; Man, Menlisa L.S.; Ling, Karen K.Y.; Ip, Nancy Yuk-Yu; Simon, Joseph; Barnard, Eric A.; Tsim, Karl Wah Keung Article
The contents and their change of nucleosides from natural Cordyceps sinensis and cultured Cordyceps mycelia
Yaoxue Xuebao, v. 36, (6), 2001, June, p. 436-439
Li, Shao Ping; Li, Ping; Ji, Hui; Zhang, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The Cyclic AMP-Mediated Expression of Acetylcholinesterase in Myotubes Shows Contrasting Activation and Repression between Avian and Mammalian Enzymes
Molecular and Cellular Neuroscience, v. 17, (4), April 2001, p. 732-745
Choi, Roy Chi Yan; Siow, Nina Lam; Zhu, Shangquan; Wan, David Chi Cheong; Wong, Yung Hou; Tsim, Karl Wah Keung Article
The Nucleosides Contents and Their Variation in Natural Cordyceps sinensis and Cultured Cordyceps Mycelia
Journal of Chinese Pharmaceutical Sciences=药学学报, v. 10 , (4), 2001, p. 175-179
Li, Shaoping; Li, Ping; Ji, Hui; Zhu, Quan; Dong, Tina T.X.; Tsim, Karl Wah Keung Article
The nucleotides contents and their variation in natural Cordyceps sinensis and cultured Cordyceps mycelia
Journal of Chinese Pharmaceutical Sciences, v. 10, (4), 2001, p. 175-179
Li, Shaoping; Li, Ping; Ji, Hui; Zhang, Ping; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
The separation and reconstitution of active ingredients of TCM
Chinese Traditional Patent Medicine, 23: 615-616
Su, Ziren; Dong, Tina Tingxia; Chan, Jian Nan; Tsim, Karl Wah Keung Article
冬虫夏草抗肿瘤作用研究进展
中草药, v. 32, (4), 2001, p. 373-375
李绍平; 季晖; 李萍; 董婷霞; 詹华强; 李文琪 Article
毛细管电泳法测定冬虫夏草中核苷类的含量
药物分析杂志, v. 21, (2), 2001, p. 77-79
李绍平; 李萍; 季晖; 董婷霞; 詹华强 Article
Analysis of Carbohydrates from Natural Cordyceps Sinensis and Cultured Cordyceps Mycelia by HPLC
Forum of Modern Pharmaceutical Analysis, Xinhua Press, Beijing / p. 149-151
Li, Shao Ping; Dong, Ting Xia; Su, Zi Ren; Zhu, Quan; Tsim, Karl Wah Keung Book chapter
Cloning and Characterization of Acetylcholinesterase Gene in Chicken
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C. Conference paper
Cloning of Chicken Acetylcholinesterase Gene and Characterization of its Putative Promoter Activity
The 21st Annual Conference of The Hong Kong Society of Neurosciences
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C. Conference paper
NFkB Regulates the Activity of Human Acetylcholinesterase Promoter in Muscle
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Choi, Chi Yan; Siow, Lam; Cheng, Anthony W.M.; Zhang, Xiang; Wan, David C.C.; Tsim, Karl Wah Keung Conference paper
Regulation of AChR and AChE by of P2Y1 Nucleotide Receptor During the Formation of Neuromuscular Junctions
Annual Meeting Society for Neurosciences (USA), 2001-2002
Tsim, Karl Wah Keung; Choi, Chi Yan; Ling, Karen; Kong, Ling Wei; Barnard, Eric Conference paper
The Role of P2Y Nucleotide Receptors in the Formation of Neuromuscular Junctions
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Tsim, Karl Wah Keung; Barnard, Eric Conference paper
2000 7
Authentication of an animal crude drug, Zaocys, by diagnostic PCR
Biological & pharmaceutical bulletin, v. 23, (5), 2000, May, p. 585-588
Wang, Yiquan; Zhou, Kaiya; Xu, Luoshan; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Chemical comparison of Astragali Radix (Huangqi) from Different Regions of China
Natural Medicines, v. 54, (5), 2000, p. 213-218
Ma, Xia Q.; Duan, Jinao; Zhu, Dayuan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Immunoglobulin G1 Fc Fragment-Tagged Human Opioid Receptor-Like Receptor Retains the Ability to Inhibit cAMP Accumulation
Biological Signals and Receptors, v. 9, (5), September-October 2000, p. 240-247
Yung, Ying; Tsim, Karl Wah Keung; Pei, Gang; Wong, Yung Hou Article
Species identification of Radix Astragali (Huangqi) by DNA sequence of its 5S-rRNA spacer domain
Phytochemistry, v. 54, (4), 2000, Jun, p. 363-368
Ma, Xiaoqiang; Duan, Jinao; Zhu, Dayuan; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The cAMP-dependent protein kinase mediates the expression of AChE in chick myotubes
NeuroReport, v. 11, (4), 2000, MAR 20, p. 801-806
Choi, Roy Chi Yan; Siow, Nina Lam; Zhu, SQ; Tsim, Karl Wah Keung Article
The promoter of human acetylcholinesterase is activated by a cyclic adenosine 3 `,5 `-monophosphate-dependent pathway in cultured NG108-15 neuroblastoma cells
Neuroscience Letters, v. 288, (1), 2000, JUL 7, p. 81-85
Wan, DCC; Choi, Roy Chi Yan; Siow, Nina Lam; Tsim, Karl Wah Keung Article
贝母的分子生物学鉴定方法的研究
药学学报=Acta Pharmaceutica Sinica, v. 35, (4), 2000, p. 309-312
蔡朝晖; 李 萍; 董婷霞; 詹华强 Article
1999 5
A cysteine-rich form of Xenopus neuregulin induces the expression of acetylcholine receptors in cultured myotubes
Molecular and Cellular Neuroscience, v. 13, (6), June 1999, p. 415-429
Yang, Jiefei; Zhou, Hong; Choi, Roy Chi Yan; Ip, Nancy Yuk-Yu; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung Article
Lack of allelic association of dopamine D4 receptor gene polymorphisms with Parkinson's disease in a Chinese population
Movement disorders, v. 14, (2), 1999, Mar, p. 225-229
Wan, David Chi Cheong; Law, Lapkay; Ip, Denis; Cheung, W. T.; Ho, Walter; Tsim, Karl Wah Keung; Kay, Richard; Woo, Jean; Pang, Chipui Article
Molecular diversity of 5S-rRNA spacer domain in Fritillaria species revealed by PCR analysis
Planta medica, v. 65, (4), 1999, May, p. 360-364
Cai, Zhaohui; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Xenopus muscle-specific kinase: molecular cloning and prominent expression in neural tissues during early embryonic development
European Journal of Neuroscience, v. 11, (2), February 1999, p. 373-382
Fu, Amy Kit Yu; Smith, Frances D.; Zhou, Hong; Chu, Apple H.; Tsim, Karl Wah Keung; Peng, Benjamin H.; Ip, Nancy Yuk-Yu Article
蒲圻贝母组织培养鳞茎形成过程中生理生化变化研究
武汉植物学研究, v. 1999, (04), 1999, p. 314-318
蔡朝晖; 李萍; 李会军; 高山林; 董婷霞; 詹华强 Article
1998 3
Cloning of cDNAs encoding Xenopus neuregulin: expression in myotomal muscle during embryo development
Molecular Brain Research, v. 58, (1-2), July 1998, p. 69-73
Yang, Jiefei; Zhou, Hong; Pun, San; Ip, Nancy Yuk-Yu; Peng, H. Benjamin; Tsim, Karl Wah Keung Article
Over-expression of acetylcholinesterase stimulates the expression of agrin in NG108-15 cells
Neuroscience Letters, v. 248, (1), 1998, MAY 22, p. 17-20
Choi, Roy Chi Yan; Yam, SCY; Hui, BD; Wan, DCC; Tsim, Karl Wah Keung Article
The calcitonin gene-related peptide-induced acetylcholinesterase synthesis in cultured chick myotubes is mediated by cyclic AMP
Journal of Neurochemistry, v. 71, (1), July 1998, p. 152-160
Choi, Roy Chi Yan; Yung, Lisa Ying; Dong, Tina Ting Xia; Wan, David C.C.; Wong, Yung Hou; Tsim, Karl Wah Keung Article
1997 12
A globular, not a symmetric, form of acetylcholinesterase is expressed in chick motor neurons: Down-regulation toward maturity and after denervation
Journal of neurochemistry, v. 68, (2), 1997, FEB, p. 479-487
Tsim, Karl Wah Keung; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wan, DCC Article
A role of midkine in the development of the neuromuscular junction
Molecular and Cellular Neurosciences, v. 10, (1-2), 1997, p. 56-70
Zhou, Hong; Muramatsu, Takashi; Halfter, Willi M.; Tsim, Karl Wah Keung; Peng, H. Benjamin Article
Agrin-deficient myotube retains its acetylcholine receptor aggregation ability when challenged with agrin
Journal of Neurochemistry, v. 69, (6), December 1997, p. 2555-2563
Pun, San; Ng, Yu Pong; Yang, Jiefei; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung Article
Antisense agrin cDNA transfection blocks neuroblastoma cell-induced acetylcholine receptor aggregation when co-cultured with myotubes
Molecular and Cellular Neurosciences, v. 10, (1-2), 1997, p. 87-99
Pun, San; Tsim, Karl Wah Keung Article
Chick muscle expresses various ARIA isoforms: Regulation during development, denervation, and regeneration
Molecular and Cellular Neurosciences, v. 9, (2), 1997, p. 132-143
Ng, Yu Pong; Pun, San; Yang, Jiefei; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung Article
Denervation decreases the ipsilateral expression of AChE in chick lumbaric motor neurons
Neuroscience Letters, v. 232, (2), 1997, AUG 29, p. 83-86
Wan, DCC; Ng, Yu Pong; Choi, Roy Chi Yan; Cheung, PWT; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Expression and localization of endothelin converting enzyme in rat vas deferens
Life sciences, v. 60, (18), 1997, Mar, p. 1605-1612
Wan, David Chi Cheong; Luk, Sandy Ka Shing; Tsim, Karl Wah Keung; Cheung, W. T. Article
Muscle-derived neurotrophin-3 increases the aggregation of acetylcholine receptors in neuron-muscle co-cultures
NeuroReport, v. 8, (18), December 1997, p. 3895-3900
Fu, Amy Kit Yu; Ip, Fanny Chun Fai; Lai, Kwok On; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu Article
NG108-15 cells express neuregulin that induces AChR alpha-subunit synthesis in cultured myotubes
FEBS letters, v. 418, (3), 1997, Dec, p. 275-281
Pun, San; Yang, Jiefei; Ng, Yupong; Tsim, Karl Wah Keung Article
NG108-15 cells induce the expression of muscular acetylcholinesterase when co-cultured with myotubes
Neuroscience Letters, v. 236, (3), 1997, NOV 7, p. 167-170
Choi, Roy Chi Yan; Pun, S.; Dong, Tina Ting Xia; Wan, DCC; Tsim, Karl Wah Keung Article
The EGF-like domain of chick acetylcholine receptor-inducing activity (ARIA) contains its full biological activity
FEBS Letters, v. 403, (2), February 1997, p. 163-167
Yang, Jiefei; Ng, Yu Pong; Pun, San; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung Article
组培蒲圻贝母鳞茎形成过程中的同工酶电泳分析
中国中药杂志, v. 1997, (01), 1997
蔡朝晖; 高山林; 李萍; 董婷霞; 詹华强 Article
1996 4
Calcitonin gene-related peptide increases the expression of acetylcholinesterase in cultured chick myotubes
Neuroscience Letters, v. 217, (2-3), 1996, OCT 18, p. 165-168
Choi, Roy Chi Yan; Leung, PWY; Dong, Tina Ting Xia; Wan, DCC; Tsim, Karl Wah Keung Article
Cerebellar granule cells express a specific isoform of agrin that lacks the acetylcholine receptor aggregating activity
FEBS letters, v. 379, (1), 1996, Jan, p. 63-68
So, K. L.; Pun, San; Wan, David Chi Cheong; Tsim, Karl Wah Keung Article
Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury
Journal of Neurochemistry, v. 67, (4), October 1996, p. 1607-1612
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu Article
Extracellular and asymmetric forms of acetylcholinesterase are expressed on cholinergic and noncholinergic terminal neuropil of the developing chick retina
Cell and Tissue Research, v. 286, (1), 1996, Oct, p. 13-22
Rei?, Yvonne; Kr?ger, Stephan; Grassi, Jaques; Tsim, Karl Wah Keung; Willbold, Elmar; Layer, Paul Gottlob Article
1995 3
Cloning of the α component of the chick ciliary neurotrophic factor receptor: Developmental expression and down-regulation in denervated skeletal muscle
Journal of Neurochemistry, v. 65, (6), December 1995, p. 2393-2400
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu Article
Prenatal cocaine exposure revealed minimal postnatal changes in rat striatal dopamine D2 receptor sites and mRNA levels in the offspring
Molecular Neurobiology, v. 11, (1-3),p. 67-76
Stadlin, Alfreda; Choi, Heung Ling; Tsim, Karl Wah Keung; Tsang, David Article
Truncated form of pro-acetycholine receptor-inducing activity (ARIA) induces AChR α-subunit but not AChE transcripts in cultured chick myotubes
Neuroscience Letters, v. 198, (2), 1995, Sep, p. 107-110
Pun, San; Tsim, Karl Wah Keung Article
1992 3
cDNA that encodes active agrin
Neuron, v. 8, (4), 1992, Apr, p. 677-690
Tsim, Karl Wah Keung; Rüegg, Markus Andreas; Escher, Gérard; Kr?ger, Stephan; McMahan, Uel Jackson Article
The agrin gene codes for a family of basal lamina proteins that differ in function and distribution
Neuron, v. 8, (4), 1992, p. 691-699
Rüegg, Markus Andreas; Tsim, Karl Wah Keung; Horton, Sharon E.; Escher, Gérard; Kr?ger, Stephan; McMahan, Uel Jackson Article
Transcripts for the acetylcholine receptor and acetylcholine esterase show distribution differences in cultured chick muscle cells
Journal of Cell Biology, v. 118, (5), 1992, p. 1201-1212
Tsim, Karl Wah Keung; Greenberg, Ian B.; Rimer, Mendell; Randall, William R.; Salpeter, Miriam M. Article
1989 1
Regulation of acetylcholine receptors and acetylcholinesterase in the innervation of skeletal muscle
Neuromuscular Junction., v. 13, 2004, p. 499-514
Barnard, Eric A.; Beeson, David M W; Darlison, Mark G.; Moss, Stephen J.; Randall, W. R.; Tsim, Karl Wah Keung Article
1988 5
Acetylcholinesterase antibodies and thyroid autoimmunity
Clin Exp Immunol, v. 71, 1988, p. 96-99
Weetman, AP; Tse, CK; Randall, WR; Tsim, Karl Wah Keung; Barnard, EA Article
An asymmetric form of muscle acetylcholinesterase contains three subunit types and two enzymic activities in one molecule
Proceedings of the National Academy of Sciences of the United States of America, v. 85, (4), 1988, p. 1262-1266
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A. Article
Identification of a 17S asymmetric butyrylcholinesterase in chick muscle by monoclonal antibodies
Neurosci Lett, v. 86, 1988, p. 245-249
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A. Article
Monoclonal antibodies specific for the different subunits of asymmetric acetylcholinesterase from chick muscle.
Journal of Neurochem, v. 51, (1), 1988, p. 95-104
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A. Article
Synaptic acetylcholinesterase of chicken muscle changes during development from a hybrid to a homogeneous enzyme
EMBO Journal, v. 7, (8), 1988, p. 2451-2456
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A. Article
1987 1
Monoclonal antibodies against chicken brain acetylcholinesterase: their use in immunopurification and immunochemistry to demonstrate allelic variants of the enzyme
European Journal of Biochemistry, v. 164, (1), 1987, p. 95-102
Randall, William R.; Tsim, Karl Wah Keung; Lai, Josephine; Barnard, Eric A. Article
1985 2
Prolactin receptor in rat liver: Sex difference in estrogenic stimulation and imprinting of the responsiveness to estrogen by neonatal androgen in male rats
Molecular and Cellular Endocrinology, v. 40, (2-3), p. 99-105
Tsim, Karl Wah Keung; Pak, Raphael; Cheng, Christopher Hon Ki Article
The role of neonatal and pubertal gonadal hormones in regulating the sex dependence of the hepatic microsomal testosterone 5-reductase activity in the rat
Journal of Endocrinology, v. 106, (1), p. 71-79
Pak, Raphael; Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki Article
1984 3
Evidence for the involvement of essential sulphydryl group in rat hepatic lactogenic receptor but not in somatogenic receptor
Molecular and Cellular Endocrinology, v. 38, (1), 1984, p. 61-66
Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki Article
Pubertal gonadal hormones in modulating the testosterone dependency of hepatic aryl hydrocarbon hydroxylase in female rats
Pharmacology, v. 29, (3), 1984, p. 121-127
Pak, Raphael; Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki Article
Rat hepatic prolactin receptor: Pubertal exposure to sex steroid alters responsively to testosterone
Int J Peptide Protein Res, v. 23, 1984, p. 521-527
Cheng, Christopher H. K.; Tsim, Karl Wah Keung; Wai, M. K. Article
Article 21
A prepared platelet-rich plasma extract, namely Self-Growth Colony, inhibits melanogenesis by down-regulating microphthalmia-associated transcription factor in skin melanocyte
Journal of Cosmetic Dermatology, v. 20, (10), 25 April 2021, p. 3278-3288
Guo, Maggie Suisui; Wu, Qiyun; Lai, Queenie Wing Sze; Wang, Xiaoyang; Bai, Panzhu; Fung, Wing Chi; Dong, Tina Tingxia; Tsim, Karl Wah Keung
A specific and bioactive polysaccharide marker for Cordyceps
Carbohydrate Polymers, v. 269, October 2021, article number 118343
Li, Li-Feng; But, Grace Wing-Chiu; Zhang, Quan-Wei; Liu, Man; Chen, Miao-Miao; Wen, Xin; Wu, Hoi-Yan; Cheng, Hui-Yuan; Puno, Pema-Tenzin; Zhang, Ji-Xia; Fung, Hau-Yee; Bai, Su-Ping; Wong, Tin-Long; Zhao, Zhong-Zhen; Cao, Hui; Tsim, Karl Wah Keung; Shaw, Pang-Chui; Han, Quan-Bin; Sun, Han-Dong
An optimized extract, named Self-Growth Colony, from platelet-rich plasma shows robust skin rejuvenation and anti-ageing properties: a novel technology in development of cosmetics
Skin Pharmacology and Physiology, v. 34, (2), April 2021, p. 74-85
Chan, Kar Lun Gallant; Guo, Suisui Maggie; Dai, Kun; Lai, Wing Sze; Fung, Wing Chi; Zheng, Zhongyu; Wu, Qiyun; Man, King Ki; Dong, Tingxia; Tsim, Karl Wah Keung
Astragaloside IV, a saponin from Astragalus membranaceus var. mongholicus, induces expressions of heme recycle proteins via signaling of Nrf2/ARE in cultured macrophages
Journal of Ethnopharmacology, v. 265, 30 January 2021, article number 113389
Gong, Guowei; Yu, Huiru; Zheng, Yuzhong; Qi, Baohui; He, Huan; Yin, Tianpeng; Dong, Ting Xia; Tsim, Karl Wah Keung
Biological Evaluation and Transcriptomic Analysis of Corylin as an Inhibitor of Osteoclast Differentiation
International Journal of Molecular Sciences, v. 22, (7), March 2021, article number 3540, p. 1-18
Yu, Xiaodan; Xiao, Jian; Zhao, Shizheng; Kong, Xiang-Peng; Kwan, Kin Leung; Zheng, Zhongyu; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung
Copper promoting oyster larval growth and settlement: Molecular insights from RNA-seq
Science of The Total Environment, v. 784, August 2021, article number 147159
Li, Yunlong; Tsim, Wah-Keung; Wang, Wen-Xiong
Danggui Buxue Tang, a Chinese herbal decoction containing Astragali Radix and Angelicae Sinensis Radix, improves mitochrondial bioenergetics in osteoblast
Phytomedicine, v. 88, July 2021, article number 153605
Kwan, Kin Leung; Dong, Ting Xia; Tsim, Karl Wah Keung
Dimeric Tacrine(10)-hupyridone as a Multitarget-Directed Ligand to Treat Alzheimer's Disease
ACS Chemical Neuroscience, v. 12, (13), July 2021, p. 2462-2477
Xuan, Zhenquan; Gu, Xinmei; Yan, Sicheng; Xie, Yanfei; Zhou, Yiying; Zhang, Hui; Jin, Haibo; Hu, Shengquan; Mak, Marvin S.H.; Zhou, Dongsheng; Tsim, Karl Wah Keung; Carlier, Paul R.; Han, Yifan; Cui, Wei
Edible Bird's Nest, an Asian Health Food Supplement, Possesses Moisturizing Effect by Regulating Expression of Filaggrin in Skin Keratinocyte
Frontiers in Pharmacology, v. 12, 20 July 2021, article number 685982
Lai, Wing Sze; Guo, Suisui; Wu, Qiyun; Liao, Zhitao; Guan, Dongshi; Dong, Tingxia; Tong, Penger; Tsim, Karl Wah Keung
Feeding containing the aerial part of Scutellaria baicalensis promotes the growth and nutritive value of rabbit fish Siganus fuscescens
Food Science and Nutrition, 28 July 2021
Xia, Yiteng; Cheng, Hok Chi; Zheng, Zhongyu; Wu, Qiyun; Dong, Ting Xia; Duan, Ran; Qin, Qi Wei; Wang, Wenxiong; Tsim, Karl Wah Keung
Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer
Phytomedicine, v. 80, January 2021, article number 153370
Lou, Jian Shu; Zhao, Li Ping; Huang, Zhi Hui; Chen, Xia Yin; Xu, Jing Ting; Tai, William Chi Shing; Tsim, Karl Wah Keung; Chen, Yi Tao; Xie, Tian
Ginsenosides attenuate bioenergetics and morphology of mitochondria in cultured PC12 cells under the insult of amyloid beta-peptide
Journal of Ginseng Research, v. 45, (4), July 2021, p. 473-481
Kwan, Kin Leung; Yun, Huang; Dong, Ting Xia; Tsim, Karl Wah Keung
Integrated Omics Reveals the Orchestrating Role of Calycosin in Danggui Buxue Tang, a Herbal Formula Containing Angelicae Sinensis Radix and Astragali Radix, in Inducing Osteoblastic Differentiation and Proliferation
Frontiers in Pharmacology, v. 12, June 2021, article number 670947
Kwan, Kin Leung; Wong, Tin Yan; Yu, Xiaodan; Dong, Ting Xia; Lam, Hei Ning; Tsim, Karl Wah Keung
Luteolin stimulates the NGF-induced neurite outgrowth in cultured PC12 cells through binding with NGF and potentiating its receptor signaling
Food & Function, v. 12, (22), 15 November 2021, p. 11525-11525
Gao, Alex Xiong; Xia, Tracy Chen-Xi; Mak, Marvin Shing-Hung; Kwan, Kenneth Kin-Leung; Zheng, Brody Zhong-Yu; Xiao, Jian; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung
Mass spectrometry-based multi-omics analysis reveals the thermogenetic regulation of herbal medicine in rat model of yeast-induced fever
Journal of Ethnopharmacology, v. 279, October 2021, article number 114382
Kwan, Kin Leung; Wong, Tin Yan; Wu, Qiyun; Dong, Ting Xia; Lam, Hei Ning; Tsim, Karl Wah Keung
Promising tacrine/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget
Journal of Neurochemistry, July 2021
Mak, Shing Hung; Li, Wenming; Fu, Hongjun; Luo, Jialie; Cui, Wei; Hu, Shengquan; Pang, Yuanping; Carlier, Paul R.; Tsim, Karl Wah Keung; Pi, Rongbiao; Han, Yifan
The binding of kaempferol-3-O-rutinoside to vascular endothelial growth factor potentiates anti-inflammatory efficiencies in lipopolysaccharide-treated mouse macrophage RAW264.7 cells
Phytomedicine, v. 80, January 2021, article number 153400
Hu, Weihui; Dai, Kun; Zheng, Zhongyu; Duan, Ran; Chan, Kar Lun Gallant; Dong, Ting Xia; Qin, Qi Wei; Tsim, Karl Wah Keung
The Mechanisms of Yu Ping Feng San in Tracking the Cisplatin-Resistance by Regulating ATP-Binding Cassette Transporter and Glutathione S-Transferase in Lung Cancer Cells
Frontiers in Pharmacology, v. 12, May 2021, article number 678126
Du, Yingqing; Zheng, Yuzhong; Yu, Ciel Xiaomei; Zhong, Lishan; Li, Yafang; Wu, Baomeng; Hu, Weihui; Zhu, Elsa Wanyi; Xie, Venus Wei; Xu, Qitian; Zhan, Xingri; Huang, Yamiao; Zeng, Liyi; Zhang, Zhenxia; Liu, Xi; Yin, Jiachuan; Zha, Guangcai; Chan, Kelvin; Tsim, Karl Wah Keung
The osteogenic function of danggui buxue tang, a herbal decoction containing astragali radix and angelicae sinensis radix, is optimized by boiling the two herbs together: Signaling analyses revealed by systems biology
Processes, v. 9, (7), July 2021, article number 1119
Kwan, Kin Leung; Wong, Tin Yan; Yu, Xiaodan; Dong, Ting Xia; Lam, Hei Ning; Tsim, Karl Wah Keung
Trewioidesine A, an Unsaturated Fatty Acid from Rhizomes of Alchornea Trewioides, Shows Synergy with NGF in Inducing Differentiation of Pheochromocytoma PC12 Cells
Natural Product Research, 16 September 2021
Peng, Zhi-Tian; Gao, Xiong; Huo, Hui-Xia; Wang, Huai-You; Guo, Qing-Bo; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung
Unique interplay between Zn2+ and nZnO determined the dynamic cellular stress in zebrafish cells
Environmental Science: Nano, v. 8, (8), August 2021, p. 2324-2335
Sun, Anqi; Tang, Benzhong; Tsim, Karl Wah Keung; Wang, Wen Xiong
Book 1
Phytocosmetics and Cosmetic Science
Phytocosmetics and Cosmetic Science / Edited By Nattaya Lourith, Karl Wah-Keung Tsim. CRC Press, 2021
Lourith, Nattaya; Tsim, Karl Wah Keung
Book chapter 1
Phytocosmetics Derived from Traditional Chinese Medicine
Phytocosmetics and Cosmetic Science / Edited by Nattaya Lourith and Karl W. K. Tsim. Boca Raton, USA : CRC Press, 2021, p. 9-21
Wu, Qiyun; Lai, Wing Sze; Guo, Suisui; Tsim, Karl Wah Keung
Conference paper 12
A screening platform of Chinese medicine in activating Wnt/β-catenin signaling pathway in cultured human embryonic kidney 293T cells: development of health food supplement for hair growth
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Yuen, Ka Wing Gary; Dong, Tingxia; Tsim, Karl Wah Keung
A screening platform of traditional Thai medicine in inhibiting β-amyloid aggregation pathway: drug development for against Alzheimer’s disease
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Ospondpant, Dusadee; Dong, Tingxia; Tsim, Karl Wah Keung
Anti-bacterial effect of traditional Chinese medicine prepared in nano drug delivery system: potential application in aquaculture feedings
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Cheng, Hok Chi; Xia, Yiteng; Dong, Tingxia; Tsim, Karl Wah Keung
Edible bird's nests improve skin barrier functions through moisturization and anti-inflammation
The 17th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 13 August 2021
Lai, Wing Sze; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung
Luteolin stimulates NGF-induced neurite outgrowth in cultured PC12 cells through binding with NGF and upregulated reactive oxygen species
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Gao, Xiong; Xia, Chenxi; Dong, Tingxia; Tsim, Karl Wah Keung
Screening traditional Chinese medicine in promoting fish growth by using growth hormone-IGF1 signaling in HEK293T cells
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Zhang, Hoi Lam; Xia, Yiteng; Cheng, Hok Chi; Dong, Tingxia; Tsim, Karl Wah Keung
Scutellarin, a flavonoid from Scutellaira barbata, enhances growth factors activity on VEGFR and MAPK signaling during wound repair in HaCaT keratinocytes
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Guo, Suisui; Gao, Xiong; Wang, Xiaoyang; Hu, Weihui; Dong, Tingxia; Tsim, Karl Wah Keung
Sea buckthorn flavonoids potentiate NGF-induced neuronal differentiation
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Xia, Chenxi; Gao, Xiong; Dong, Tingxia; Tsim, Karl Wah Keung
The anti-neuroinflammatory effects of berberine and palmatine by targeting on AChE and α7 nAChR
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Xia, Yingjie; Kong, Xiangpeng; Wu, Qiyun; Xia, Yiteng; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung
The extract from aerial part of Scutellaria baicalensis as a feeding additive regulates gut microbiota and promotes the growth of Siganus fuscescens
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Xia, Yiteng; Wu, Qiyun; Cheng, Hok Chi; Dong, Tingxia; Qin, Qiwei; Wang, Wenxiong; Tsim, Karl Wah Keung
Traditional Chinese medicine promotes the anti-inflammatory effect of probiotics in fighting against skin eczema
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Chen, Yanxian; Zheng, Zhongyu; Leung, Ka Wing; Dong, Tingxia; Tsim, Karl Wah Keung
Traditional Chinese medicine protects E. coli from anti-depressants-induced mutation of having resistance to antibiotics
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM 2021), Hong Kong Convention and Exhibition Centre (Online), 12-13 August 2021
Wu, Jiahui; Dong, Tingxia; Wang, Huaiyou; Tsim, Karl Wah Keung
Article 25
A Review of Edible Jujube, the Ziziphus jujuba Fruit: A Heath Food Supplement for Anemia Prevalence
Frontiers in Pharmacology, v. 11, November 2020, article number 593655
Chen, Jianping; Tsim, Karl Wah Keung
A standardized extract of Danggui Buxue Tang decoction selectively exerts estrogenic activities distinctly from tamoxifen
Phytotherapy Research, v. 35, (3), March 2021, p. 1456-1467
Zhou, Liping; Wong, Ka-Ying; Cao, Sisi; Poon, Christina Chui-Wa; Yu, Wenxuan; Dong, Xiaoli; Tsim, Karl Wah Keung; Wong, Man-Sau
Capsaicin Inhibits the Expression of Melanogenic Proteins in Melanocyte via Activation of TRPV1 Channel: Identifying an Inhibitor of Skin Melanogenesis
Journal of Agricultural and Food Chemistry, v. 68, (50), 16 December 2020, p. 14863-14873
Wu, Qiyun; Bai, Panzhu; Xia, Yiteng; Xia, Yingjie; Xu, Bowen; Dai, Kun; Zheng, Zhongyu; Guo, Suisui; Fung, Wing Chi; Dong, Ting Xia; Tsim, Karl Wah Keung
Corylin, a flavonoid derived from Psoralea Fructus, induces osteoblastic differentiation via estrogen and Wnt/β-catenin signaling pathways
FASEB Journal, v. 34, (3), March 2020, p. 4311-4328
Yu, Xiaodan; Xu, Li Miranda; Yao, Ping; Kwan, Kin Leung; Liu, Yongxiang; Duan, Ran; Dong Ting Xia; Ko, Kam Ming; Tsim, Karl Wah Keung
Dehydrocorydaline Accounts the Majority of Anti-Inflammatory Property of Corydalis Rhizoma in Cultured Macrophage
Evidence-based Complementary and Alternative Medicine, v. 2020, November 2020, article number 4181696
Kong, Xiangpeng; Chen, Zhicong; Xia, Yingjie; Liu, Yunle; Ren, Haiqin; Wang, Cheng; Hu, Weihui; Dong, Ting Xia; Pi, Rongbiao; Tsim, Karl Wah Keung
Design, Synthesis, and Biological Evaluation of Novel Multifunctional Rolipram-Tranilast Hybrids As Potential Treatment for Traumatic Brain Injury
ACS Chemical Neuroscience, v. 11, (15), 9 July 2020, p. 2348-2360
Lu, Junfeng; Chen, Chen; Deng, Xiaobing; Mak, Marvin SH; Zhu, Zeyu; He, Xixin; Liang, Jinhao; Maddili, Swetha Kameswari; Tsim, Karl Wah Keung; Han, Yifan; Pi, Rongbiao
Discovery of a Novel Small Molecule PT109 With Multi-Targeted Effects Against Alzheimer's Disease in Vitro and in Vivo
European Journal of Pharmacology, v. 883, 15 September 2020, article number 173361
Chen, Qiuhe; Tu, Yalin; Mak, Shinghung; Chen, Jingkao; Lu, Junfeng; Chen, Chen; Yang, Xiaohong; Wang, Shengnan; Wen, Shijun; Ma, Shanshan; Li, Mingtao; Han, Yifan; Tsim, Karl Wah Keung; Pi, Rongbiao
Evaluation of Anti-Inflammatory Components of Guizhi Fuling Capsule, an Ancient Chinese Herbal Formula, in Human Umbilical Vein Endothelial Cells
Evidence-based Complementary and Alternative Medicine, v. 2020, October 2020, article number 2029134
Zheng, Yuzhong; Xin, Guizhong; Gong, Guowei; Dong, Tingxia; Li, Ping; Tsim, Karl Wah Keung
Fermentation of Danggui Buxue Tang, an ancient Chinese herbal mixture, together with Lactobacillus plantarum enhances the anti-diabetic functions of herbal product
Chinese Medicine (United Kingdom), v. 154, (1), 11 September 2020, article number 98
Guo, Rui; Guo, Shuchen; Gao, Xiong; Wang, Huaiyou; Hu, Weihui; Duan, Ran; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Integrated Assessment of Medicinal Rhubarb by Combination of Delayed Luminescence and HPLC Fingerprint With Emphasized on Bioactivities Based Quality Control
Chinese Medicine (United Kingdom), v. 15, (1), July 2020, article number 72
Sun, Mengmeng; Wu, Hongwei; He, Min; Jia, Yusheng; Wang, Lixue; Liu, Ting; Hui, Lianqiang; Li, Li; Wei, Shengli; Van Wijk, Eduard; Van Wijk, Roeland; Tsim, Karl Wah Keung; Li, Chun; Wang, Mei
Integration of Organ Metabolomics and Proteomics in Exploring the Blood Enriching Mechanism of Danggui Buxue Decoction in Hemorrhagic Anemia Rats
Journal of Ethnopharmacology, v. 261, 28 October 2020, article number 113000
Shi, Xuqin; Zhu, Zhenhua; Yue, Shijun; Tang, Yuping; Chen, Yanyan; Pu, Zongjin; Tao, Huijuan; Zhou, Guisheng; Yang, Ye; Guo, Mengjie; Dong, Ting Xia Tina; Tsim, Karl Wah Keung; Duan, Jinao
Interacting with α7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages
Acta Pharmaceutica Sinica B, v. 10, (10), October 2020, p. 1926-1942
Liu, Yunle; Xia, Yingjie; Kong, Xiangpeng; Guo, Suisui; Yu, Xiaodan Anna; Zheng, Zhongyu; Mak, Shing Hung; Xu, Li; Tsim, Karl Wah Keung
Jellyfish genomes reveal distinct homeobox gene clusters and conservation of small RNA processing
Nature Communications, v. 11, (1), December 2020, article number 3051
Nong, Wenyan; Cao, Jianquan; Li, Yiqian; Qu, Zhe; Sun, Jin; Swale, Thomas; Yip, Ho Yin; Qian, Peiyuan; Qiu, Jian-Wen; Kwan, Hoi Shan; Bendena, William; Tobe, Stephen; Chan, Ting Fung; Yip, Kevin Y.; Chu, Ka Hou; Ngai, Sai Ming; Tsim, Karl Wah Keung; Holland, Peter W.H.; Hui, Jerome H.L.
Kaempferol, a Major Flavonoid in Ginkgo Folium, Potentiates Angiogenic Functions in Cultured Endothelial Cells by Binding to Vascular Endothelial Growth Factor
Frontiers in Pharmacology, v. 11, April 2020, article number 526
Hu, Weihui; Wang, Huai-You; Xia, Yiteng; Dai, Diana Kun; Xiong, Qing-Ping; Dong, Tina Ting-Xia; Duan, Ran; Chan, Kar Lun Gallant; Qin, Qi-Wei; Tsim, Wah-Keung
Piceatannol, a Natural Analog of Resveratrol, Exerts Anti-angiogenic Efficiencies by Blockage of Vascular Endothelial Growth Factor Binding to Its Receptor
Molecules, v. 25, (17), August 2020, article number 3769
Hu, Weihui; Dai, Kun; Zheng, Zhongyu; Duan, Ran; Dong, Tingxia; Qin, Q.-W.; Tsim, Karl Wah Keung
Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties
Frontiers in Pharmacology, v. 10, January 2020, article number 1549
Gong, Guowei; Huang, Jing; Yang, Yang; Qi, Baohui; Han, Guangyi; Zheng, Yuzhong; He, Huan; Chan, Kelvin; Tsim, Karl Wah Keung; Dong, Tingxia
Shexiang Baoxin Pill, a Traditional Chinese Herbal Formula, Rescues the Cognitive Impairments in APP/PS1 Transgenic Mice
Frontiers in Pharmacology, v. 11, July 2020, article number 1045
Hu, Weihui; Mak, Shing Hung; Zheng, Zhongyu; Xia, Yingjie; Xu, Miranda Li; Duan, Ran; Dong, Ting Xia; Li, Shao-Ping; Zhan, Chang-Sen; Shang, Xiao-Hui; Tsim, Karl Wah Keung
Significant combination of Aβ aggregation inhibitory and neuroprotective properties in silico, in vitro and in vivo by bis(propyl)-cognitin, a multifunctional anti-Alzheimer’s agent
European Journal of Pharmacology, v. 876, 5 June 2020, article number 173065
Hu, Shengquan; Xian, Yanfang; Fan, Yubo; Mak, Shinghung; Wang, Jiajun; Tang, Jing; Pang, Yuanping; Pi, Rongbiao; Tsim, Karl Wah Keung; Liu, Fufeng; Lin, Zhixiu; Han, Yifan
Solar light induces expression of acetylcholinesterase in skin keratinocytes: Signalling mediated by activator protein 1 transcription factor
Neurochemistry International, v. 141, December 2020, article number 104861
Wu, Qiyun; Bai, Panzhu; Xia, Yingjie; Queenie W. S. Lai; Guo, Maggie S. S.; Dai, Kun; Zheng, Zhongyu; Ling, Christine S. J.; Dong, Tina T. X.; Pi, Rongbiao; Tsim, Karl Wah Keung
Solar light induces the release of acetylcholine from skin keratinocytes affecting melanogenesis
FASEB Journal, v. 34, (7), July 2020, p. 8941-8958
Wu, Qiyun; Xia, Yiteng; Dai, Kun; Bai, Panzhu; Kwan, Kenneth K. L; Guo, Maggie S.S.; Dong, Tina T.X.; Tsim, Karl Wah Keung
The anti-bacterial effects of aerial parts of Scutellaria baicalensis: Potential application as an additive in aquaculture feedings
Aquaculture, v. 526, September 2020, article number 735418
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Duan, Ran; Hu, Weihui; Qin, Qi-Wei; Wang, Wenxiong; Tsim, Karl Wah Keung
The Chinese Medicinal Herbs of Spleen-meridian Property Regulate Body Temperature in Yeast-induced Fever Rats
Phytomedicine, v. 74, August 2020, article number 152815
Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiangpeng; Dong, Ting Xia; Chen, Yicun; Qin, Qiwei; Tsim, Karl Wah Keung
The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix
Molecules, v. 25, (24), December 2020, article number 5914
Kong, Xiangpeng; Ren, Haiqin; Liu, Yunle; Leung, Ka Wing; Guo, Shuchen; Duan, Ran; Dong, Ting Xia; Tsim, Karl Wah Keung
The Herbal Extract Deriving From Aerial Parts of Scutellaria Baicalensis Shows Anti-inflammation and Anti-hypoxia Responses in Cultured Fin Cells From Rabbit Fish
Fish & Shellfish Immunology, v. 106, November 2020, p. 71-78
Xia, Yiteng; Hu, Weihui; Wu, Qiyun; Dong, Tingxia Tina; Duan, Ran; Xiao, Jian; Li, Shaoping; Wang, Wenxiong; Qin, Qiwei; Tsim, Karl Wah Keung
发酵柴胡地上部分定量分析及其抗菌活性成分预测
中国中药杂志=China Journal of Chinese Materia Medica, v. 45, (17), September 2020, p. 4238-4245
郭舒臣; 郭瑞; 夏翊腾; 董婷霞; 王怀友; 詹华强
Conference paper 4
Corylin inhibits RANKL-induced osteoclastogenesis: signaling mediated by NF-κB pathways and direct target identification
30th Australian & New Zealand Bone and mineral Society Annual Scientific Meeting, Virtual Meeting, 12-14 October 2020
Yu, Xiaodan; Kong, Xiangpeng; Zhao, Shizheng; Kwan, Kenneth Kin-Leung; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung
Edible Bird’s Nests Promote Skin Hydration through Skin Barrier Protection
The 16th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2020
Lai, Wing Sze; Chan, Kar Lun Gallant; Wu, Qiyun; Wong, Chun Fai; Dong, Tingxia; Tsim, Karl Wah Keung
Integrated omics dissection of the effect of natural product decoction on cultured osteoblasts
8th Asia-Oceania Mass Spectrometry Conference (AOMSC 2020), Macau, China, 5-7 January 2020
Kwan, Kin Leung; Tsim, Karl Wah Keung; Lam, Henry
Multi-omics investigation of synergistic effects of traditional Chinese medicine herbal decoction on cultured osteoblasts
68th American Society for Mass Spectrometry Conference (ASMS Reboot 2020), Online, 1-12 June 2020
Kwan, Kin Leung; Wong, Tin Yan; Yu, Anna Xiaodan; Dong, Tingxia; Lam, Henry Hei Ning; Tsim, Karl Wah Keung
Article 26
Activation of G Protein-Coupled Receptor 30 by Flavonoids Leads to Expression of Acetylcholinesterase in Cultured PC12?Cells
Chemico-Biological Interactions, v. 306, June 2019, p. 147-151
Liu, Yunle; Xu, Miranda Li; Xia, Yingjie; Kong, Xiangpeng; Wu, Qiyun; Dong, Tingxia Ting Xia; Tsim, Karl Wah Keung
An Ancient Chinese Herbal Decoction Containing Angelicae Sinensis Radix, Astragali Radix, Jujuba Fructus, and Zingiberis Rhizoma Recens Stimulates the Browning Conversion of White Adipocyte in Cultured 3T3-L1 Cells
Evidence-based Complementary and Alternative Medicine, v. 2019, June 2019, article number 3648685
Gong, Guowei; Han, Guangyi; He, Huan; Dong, Tina T. X.; Tsim, Karl Wah Keung; Zheng, Yuzhong
An Optimization of Ultra-sonication-assisted Extraction From Flowers of Apocynum Venetum in Targeting to Amount of Free Amino Acids Determined by UPLC-MS/MS
Food Quality and Safety, v. 3, (1), 11 April 2019, p. 52-60
Jin, Yan; Wang, Caroline Yang; Hu, Weihui; Huang, Yun; Xu, Li; Wang, Huaiyou; Kong, Xiangpeng; Chen, Yicun; Dong, Tingxia; Qin, Qiwei; Tsim, Karl Wah Keung
Asarones From Acori Tatarinowii Rhizoma Stimulate Expression and Secretion of Neurotrophic Factors in Cultured Astrocytes
Neuroscience Letters, v. 707, August 2019, article number 134308
Lam, Yin Ching; Wu, Qiyun; Hu, Weihui; Yao, Ping; Wang, Huai-You; Dong, Ting Xia; Tsim, Karl Wah Keung
Binding of Resveratrol to Vascular Endothelial Growth Factor Suppresses Angiogenesis by Inhibiting the Receptor Signaling
Journal of Agricultural and Food Chemistry, v. 67, (4), January 2019, p. 1127-1137
Hu, Weihui; Duan, Ran; Xia, Yiteng; Xiong, Qing-Ping; Wang, Huai-You; Chan, Kar Lun Gallant; Liu, Si-Yue; Dong, Ting Xia; Qin, Qi-Wei; Tsim, Karl Wah Keung
Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, Modulates Mitochondrial Bioenergetics in Cultured Cardiomyoblasts
Frontiers in Pharmacology, v. 10, (JUN), June 2019, article number 614
Kwan, Kin Leung; Huang, Yun; Leung, Ka Wing; Dong, Tina Xia; Tsim, Karl Wah Keung
Danggui Buxue Tang, an ancient Chinese herbal decoction, protects β-amyloid-induced cell death in cultured cortical neurons
BMC Complementary and Alternative Medicine, v. 19, (1), January 2019, article number 9
Gong, Guowei; Qi, Baohui; Liang, Yanting; Dong, Ting Xia; Wang, Huai you; Tsim, Karl Wah Keung; Zheng, Yuzhong
Differentiation of Erythroblast Requires the Dimeric Form of Acetylcholinesterase: Interference With Erythropoietin Receptor
Chemico-Biological Interactions, v. 308, August 2019, p. 317-322
Xua, Miranda L.; Luk, Wilson K. W.; Liu, Yunle; Kong, Xiang P.; Wu, Qi Y.; Xia, Yingjie; Dong, Tina T. X.; Tsim, Karl Wah Keung
Isoorientin Derived from Gentiana Veitchiorum Hemsl. Flowers Inhibits Melanogenesis by Down-regulating MITF-induced Tyrosinase Expression
Phytomedicine, v. 57, April 2019, p. 129-136
Wu, Qiyun; Wong, Chun Fai; Wang, Cheng; Fung, Hei Yiu; Wong, Oi Ying; Chan, Kar Lun Gallant; Dong, Tina Ting-Xia; Chen, Yicun; Tsim, Karl Wah Keung
Isorhynchophylline Ameliorates Cognitive Impairment via Modulating Amyloid Pathology, Tau Hyperphosphorylation and Neuroinflammation: Studies in a Transgenic Mouse Model of Alzheimer's Disease
Brain, Behavior, and Immunity, v. 82, November 2019, p. 264-278
Li, Huiqin; Ip, Siu Po; Yuan, Qiuju; Zheng, Guoqing; Tsim, Karl Wah Keung; Dong, Ting Xia; Lin, Ge; Han, Yifan; Liu, Yue; Xian, Yanfang; Lin, Zhixiu
Molecular characteristics and function study of TNF receptor-associated factor 5 from grouper (Epinephelus coioides)
Fish and Shellfish Immunology, v. 87, April 2019, p. 730-736
Yang, Man; Han, Rui; Ni, Luyun; Luo, Xiaochun; Li, Anxing; Dan, Xueming; Tsim, Karl Wah Keung; Li, Yanwei
Ophiopogon Polysaccharide Promotes the In Vitro Metabolism of Ophiopogonins by Human Gut Microbiota
Molecules, v. 24, (16), 8 August 2019, article number 2886
Wang, Huaiyou; Guo, Shuchen; Peng, Zhitian; Wang, Cheng; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung
Polydatin Suppresses VEGF-induced Angiogenesis Through Binding with VEGF and Inhibiting Its Receptor Signaling
FASEB Journal, v. 33, (1), January 2019, p. 532-544
Hu, Weihui; Wang, Huaiyou; Kong, Xiang-Peng; Xiong, Qingping; Poon, Ka Man; Xu, Li; Duan, Ran; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung
Polysaccharide deriving from Ophiopogonis Radix promotes metabolism of ginsenosides in the present of human gut microbiota based on UPLC-MS/MS assay
Journal of Pharmaceutical and Biomedical Analysis, v. 175, 25 October 2019, article number 112779
Wang, Huaiyou; Wang, Cheng; Guo, Shuchen; Chen, Zhicong; Peng, Zhitian; Duan, Ran; Dong, T.T.X.; Tsim, Karl Wah Keung
Polysaccharide From Tuberous Roots of Ophiopogon japonicus Regulates Gut Microbiota and Its Metabolites During Alleviation of High-fat Diet-induced Type-2 Diabetes in Mice
Journal of Functional Foods, v. 63, December 2019, article number 103593
Wang, Huaiyou; Guo, Linxiu; Hu, Weihui; Peng, Zhitian; Wang, Cheng; Chen, Zhicong; Liu, Yunle; Dong, Ting Xia; Wang, Tiejie; Tsim, Karl Wah Keung
Shexiang Baoxin Pill, A Formulated Chinese Herbal Mixture, Induces Neuronal Differentiation of PC12 Cells: A Signaling Triggered by Activation of Protein Kinase A
Frontiers in Pharmacology, v. 10, October 2019, article number e01130
Xu, Miranda Li; Zheng, Zhongyu; Xia, Yingjie; Liu, Yunle; Chan, Stanley Ka Ho; Hu, Weihui; Duan, Ran; Dong, Tina Tingxia; Zhan, Chang-Sen; Shang, Xiao-Hui; Tsim, Karl Wah-Keung
Simultaneous Determination of Short-chain Fatty Acids in Human Feces by HPLC With Ultraviolet Detection Following Chemical Derivatization and Solid-phase Extraction Segmental Elution
Journal of Separation Science, v. 42, (15), August 2019, p. 2500-2509
Wang, Huai You; Wang, Cheng; Guo, Linxiu; Zheng, Yunfeng; Hu, Weihui; Dong, Tingxia; Wang, Tiejie; Tsim, Karl Wah Keung
Synergistic inhibition of acetylcholinesterase by alkaloids derived from Stephaniae tetrandrae radix, Coptidis rhizoma and Phellodendri chinensis cortex
Molecules, v.24, (24), December 2019, article number 4567
Kong, Xiangpeng; Liu, Etta Yun Le; Chen, Zhicong; Xu, Miranda Li; Yu, Anna X.D.; Wu, Qiyun; Xia, Yingjie; Duan, Ran; Dong,Ting Xia; Tsim, Karl Wah Keung
Synergy of ginkgetin and resveratrol in suppressing vegf-induced angiogenesis: A therapy in treating colorectal cancer
Cancers, v. 11, (12), December 2019, article number 1828
Hu, Weihui; Chan, Kar Lun Gallant; Duan, Ran; Wang, Huaiyou; Kong, Xiangpeng; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Tectorigenin, an isoflavone aglycone from the rhizome of Belamcanda chinensis, induces neuronal expression of erythropoietin via accumulation of hypoxia-inducible factor-1α
Phytotherapy Research, 2019
Liu, Etta Y.; Zheng, Zoey X.; Zheng, Brody Z.; Xia, Yingjie; Guo, Maggie S.; Dong, Tina T.; Tsim, Karl Wah Keung
The effect of methanol extract from Saussurea involucrata in the lipopolysaccharide-stimulated inflammation in cultured RAW 264.7 cells
Journal of Ethnopharmacology, v. 251, article number 112532
Gong, Guowei; Xie, Feng; Zheng, Yuzhong; Hu, Weihui; Qi, Baohui; He, Huan; Dong, Ting Xia; Tsim, Karl Wah Keung
The Effects of Shexiang Baoxin Pill in Alzheimer’s Disease and Inflammation
Research on Pharmacology, v. 1, (1), September 2019, p. 1-14
Xia, Yingjie; Xu, Li; Zheng, Zhongyu; Zhan, Changsen; Shang, Xiaohui; Dong, Tingxia; Hu, Weihui; Chan, Ka Ho; Duan, Ran; Tsim, Karl Wah Keung
UPLC-MS/MS法与HPLC-FLD法分析检测中药中的黄曲霉毒素
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 39, (7), 2019, p. 1272-1278
郭舒臣; 汪成; 彭治添; 董婷霞; 詹华强
毛冬青质量标准的改进研究
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 39, (8), 2019, p. 1416-1424
王怀友; 汪成; 郑玉忠; 邓伟麟; 段然; 董婷霞; 詹华强
瓜子金质量标准研究
时珍国医国药=Lishizhen Medicine and Materia Medica Research, v. 30, (9), September 2019, p. 2159-2163
王怀友; 汪成; 郑玉忠; 邓伟麟; 段然; 董婷霞; 詹华强
药对配伍效应与功效物质现代研究方法与策略
药学学报=Acta Pharmaceutica Sinica, v. 54, (9), September 2019, p. 1564-1573
唐于平; 尚尔鑫; 陈艳琰; 乐世俊; 史旭芹; 董婷霞; 詹华强; 段金廒
Conference paper 20
AChE regulates LPS-induced inflammatory response in macrophages
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Xia, Yingjie; Liu, Yunle; Kong, Xiangpeng; Wu, Qiyun; Guo, Suisui; Zheng, Zhongyu; Mak, Shing Hung; Sui, Yixuan; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung
Assembly of PRiMA-linked form of acetylcholinesterase in neurons: the role of enzyme inhibitor acting as a chemical chaperon
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Mak, Shing Hung; Liu, Yunle; Xia, Yingjie; Kong, Xiangpeng; Guo, Suisui; Yu, Xiaodan; Zheng, Zhongyu; Duan, Ran; Tsim, Karl Wah Keung
Capsaicin inhibits melanogenesis through downregulating tyrosinase expression
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Wu, Qiyun; Bai, Panzhu; Xia, Yiteng; Dai, Kun; Zheng, Zhongyu; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung
Corylin induces bone differentiation and metabolic profiling: illustration by using cultured osteoblasts and bone micromass
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Yu, Xiaodan; Xu, Li; Yao, Ping; Kwan, Kin Leung; Liu, Yongxiang; Dong, Tingxia; Ko, Kam Ming; Tsim, Karl Wah Keung
Fractionation of proteins in identifying and understanding the health-promoting functions of edible bird’s nests
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15 - 16 August 2019
Lai, Wing Sze; Chan, Kar Lun Gallant; Wu, Qiyun; Zheng, Zhongyu; Dong, Tingxia; Tsim, Karl Wah Keung
HerboChips: a screening platform for drug development from traditional Chinese medicine on a chip
19th International Congress of the International Society for Ethanopharmacology, ISE 2019, Dresden, Germany, 12-14 June 2019
Tsim, Karl Wah Keung; Hu, Weihui; Duan, Ran; Dong, Tingxia; Wang, Huaiyou; Xia, Yiteng
Kaempferol, a major flavonoid in Ginkgo Folium, binds to vascular endothelial growth factor and potentiates angiogenic functions in cultured endothelial cells
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Hu, Weihui; Wang, Huaiyou; Duan, Ran; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung
Kaempferol, a major flavonoid in Ginkgo Folium, binds to vascular endothelial growth factor and potentiates angiogenic functions in cultured endothelial cells
19th International Congress of the International Society for Ethanopharmacology, ISE 2019, Dresden, Germany, 12-14 June 2019
Hu, Weihui; Xia, Yiteng; Duan, Ran; Dong, Tingxia; Wang, Huaiyou; Tsim, Karl Wah Keung
Mass spectrometry based omics technology to reveal the effect of herbal decoction in cultured osteoblasts
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Kwan, Kin Leung; Wong, Tin Yan; Yu, Xiaodan; Leung, Ka Wing; Dong, Tingxia; Lam, Hei Ning; Tsim, Karl Wah Keung
Mass-Spectrometry-Based Omics Technology to Reveal the Effect of Herbal Decoction in Cultured Osteoblasts
67th ASMS Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, 2-6 June 2019
Kwan, Kin Leung; Wong, Tin Yan; Yu, Xiaodan; Leung, Ka Wing; Dong, Tingxia; Lam, Hei Ning; Tsim, Karl Wah Keung
Pharmacological characterizations of multifunctional anti-dementia NMDA receptor antagonist memantine nitrates
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Mak, Shing Hung; Han, Yifan; Zhang, Zaijun; Tsim, Karl Wah Keung
Polysaccharide from tuberous roots of Ophiopogon japonicus regulates gut microbiota and its metabolites during alleviation of HFD-induced type-2 diabetes in mice
19th International Congress of the International Society for Ethanopharmacology, ISE 2019, Dresden, Germany, 12-14 June 2019
Wang, Huaiyou; Wang, Cheng; Hu, Weihui; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung
SGC - An advance autologous skin rejuvenalim lechnoIogy
Cosmetic and Beauty International Conference 2019 (CBIC 2019): Sustainable Cosmetic and Beauty Innovations, Mae Fah Luang University, Thailand, 7-9 October 2019
Chan, Kar Lun Gallant; Tsim, Karl Wah Keung
Sunlight stimulation induces the release of acetylcholine from skin keratinocyte via signaling mediated by opsin
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Wu, Qiyun; Xia, Yiteng; Xia, Yingjie; Bai, Panzhu; Dai, Kun; Chen, Yicun; Dong, Ting Xia; Tsim, Karl Wah Keung
The anti-bacterial effects of aerial parts of Scutellaria baicalnsis: potential application as an additive in aquaculture feedings
15th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Duan, Ran; Qin, Qiwei; Wang, Wenxiong; Tsim, Karl Wah Keung
The anti-bacterial effects of aerial parts of Scutellaria baicalnsis: potential application as an additive in aquaculture feedings
19th International Congress of the International Society for Ethanopharmacology, ISE 2019, Dresden, Germany, 12-14 June 2019
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Duan, Ran; Qin, Qiwei; Wang, Wenxiong; Tsim, Karl Wah Keung
The anti-inflammatory efficiencies of kaempferol-3-O-rutinoside and donepezil in lipopolysaccharide-treated mouse macrophage RAW264.7 cells
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Hu, Weihui; Duan, Ran; Xia, Yingjie; Dong, Ting Xia; Tsim, Karl Wah Keung
The effect of Shexiang Baoxin Pill in Alzheimer’s disease and inflammation
5th International Postgraduate Symposium on Chinese Medicine, IPSCM 2019 第15届国际研究生中医药研讨会, Hong Kong, 15-16 August 2019
Xia, Yingjie; Xu, Li; Zheng, Zhongyu; Dong, Tingxia; Hu, Weihui; Chan, Ka Ho; Duan, Ran; Tsim, Karl Wah Keung
Traditional Chinese medicine as the innovative cosmetics
Cosmetic and Beauty International Conference 2019 (CBIC 2019): Sustainable Cosmetic and Beauty Innovations, Mae Fah Luang University, Thailand, 7-9 October 2019
Tsim, Karl Wah Keung
Transcriptional regulation of acetylcholinesterase in skin during melanogenesis: an enzyme in controlling skin color
The 16th International Symposium on Cholinergic Mechanisms (ISCM-XVI), Weizmann Institute of Science, Rehovot, Israel, 8-13 December 2019
Tsim, Karl Wah Keung; Mak, Shing Hung; Wu, Qiyun; Xia, Yingjie; Hu, Weihui; Dong, Tingxia; Duan, Ran; Chen, Yicun
Article 27
2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Alterations in Myogenic Differentiation of C2C12 Cells
Environmental Pollution, v.235, April 2018, p. 965-973
Xie, Heidi Q.; Xia, Yingjie; Xu, Tuan; Chen, Yangsheng; Fu, Hualing; Li, Yunping; Luo, Yali; Xu, Li; Tsim, Karl Wah Keung; Zhao, Bin
A Chinese herbal decoction, Jian-Pi-Yi-Shen, regulates the expressions of erythropoietin and pro-inflammatory cytokines in cultured cells
BMC Complementary and Alternative Medicine, v. 18, (1), 3 April 2018, article number 119
Chen, jianping; Gong, Guowei; Liu, xiaoyan; Li, Zhonggui; Qi, airong; Dong, tingxia; Yi, tiegang; Tsim, Karl Wah Keung; Li, shunmin
A Chinese Herbal Preparation, Xiao-Er-An-Shen Decoction, Exerts Neuron Protection by Modulation of Differentiation and Antioxidant Activity in Cultured PC12 Cells
Evidence-based Complementary and Alternative Medicine, v. 2018, 2018, article number 8670421
Li, Zhonggui; Lam, Yin Ching; Liu, Xiaoyan; Qi, Airong; Yao, Ping; Dong, Tina T. X.; Yi, Tiegang; Tsim, Karl Wah Keung; Chen, Jianping
A Comprehensive Proteomics Study on Edible Bird's Nest Using New Monoclonal Antibody Approach And Application In Quality Control
Journal of Food Composition And Analysis, v. 66, March 2018, p. 145-151
Wong, Chun Fai; Chan, Kar Lun Gallant; Wu, Long; Lam, Hei Ning; Yao, Ping; Dong, Tina T. X.; Tsim, Karl Wah Keung
An UPLC-MS/MS method for simultaneous determination of multiple constituents in Guizhi Fuling capsule with ultrafast positive/negative ionization switching
Chinese Journal of Natural Medicines, v. 16, (4), April 2018, p. 313-320
Zhang, Rong-Hua; Li, Chao-Ran; Yang, Hua; Li, Meng-Ning; Tsim, Karl Wah Keung; Li, Ping; Gao, Wen
Bone Protective Effects of Danggui Buxue Tang Alone and in Combination With Tamoxifen or Raloxifene in vivo and in vitro
Frontiers in Pharmacology, v. 9, 13 August 2018, article number 779
Zhou, Li-Ping; Wong, Ka-Ying; Yeung, Hoi-Ting; Dong, Xiao-Li; Xiao, Hui-Hui; Gong, G. W. Amy; Tsim, Karl Wah Keung; Wong, Man-Sau
Calycosin Orchestrates Osteogenesis of Danggui Buxue Tang in Cultured Osteoblasts: Evaluating the Mechanism of Action by Omics and Chemical Knock-out Methodologies
Frontiers in Pharmacology, v. 9, (36), February 2018, article number 36
Gong, Amy G. W.; Duan, Ran; Wang, Huai Y.; Dong, Ting Xia; Tsim, Karl Wah Keung
Complete digestion of edible bird's nest releases free N-acetylneuraminic acid and small peptides: an efficient method to improve functional properties
Food & Function, v. 9, (10), October 2018, p. 5139-5149
Wong, Chun Fai; Chan, Kar Lun Gallant; Wu, Qiyun; Poon, Ka Man; Chen, Yicun; Dong, Tingxia; Tsim, Karl Wah Keung
Discrimination of three Siegesbeckiae Herba species using UPLC-QTOF/MS-based metabolomics approach
Food and Chemical Toxicology, v. 119, September 2018, p. 400-406
Tao, Hong-Xun; Xiong, Wei; Zhao, Guan-Ding; Peng, Yu; Zhong, Zhang-Feng; Xu, Liiang; Duan, Ran; Tsim, Karl Wah Keung; Yu, Hua; Wang, Yi-Tao
Erythropoietin Regulates The Expression of Dimeric Form of Acetylcholinesterase During Differentiation of Erythroblast
Journal of Neurochemistry, v. 146, April 2018, article number 14448, p. 390-402
Xu, Li; Luk, Kin Wai Wilson; Bi, Wenchuan; Liu, Yunle; Wu, Qiyun; Yao, Ping; Dong, tingxia; Tsim, Karl Wah Keung
Evaluation of the Pharmaceutical Properties and Value of Astragali Radix
Medicines (Basel)., v. 5, (2), 21 May 2018, article number 46
Gong, Guowei; Duan, Ran; Wang, Huaiyou; Kong, xiang; Dong, Tingxia; Tsim, Karl Wah Keung; Chan, Kelvin
Flavonoids are identified from the extract of Scutellariae Radix to suppress inflammatory-induced angiogenic responses in cultured RAW 264.7 macrophages
Scientific Reportsvolume, v. 8, (1), December 2018, article number 17412
Gong, Guowei; Wang, Huaiyou; Kong, Xiangpeng; Duan, Ran; Dong, Ting Xia; Tsim, Karl Wah Keung
Flavonoids, a Potential New Insight of Leucaena leucocephala Foliage in Ruminant Health
Journal of Agricultural and Food Chemistry, v. 66, (29), July 2018, p. 7616-7626
Xu, Yingchao; Tao, Zhenru; Jin, Yu; Yuan, Yunfei; Dong, Ting Xia; Tsim, Karl Wah Keung; Zhou, Zhongyu
Genistein, a Phytoestrogen in Soybean, Induces the Expression of Acetylcholinesterase via G Protein-coupled Receptor 30 in PC12 Cells
Frontiers in Molecular Neuroscience, v. 11, February 2018, article number 59
Liu, Yunle; Xu, Miranda L.; Jin, Yan; Wu, Qiyun; Dong, Tina T. X.; Tsim, Karl Wah Keung
Ginseng extracts modulate mitochondrial bioenergetics of live cardiomyoblasts: a functional comparison of different extraction solvents
Journal of Ginseng Research, v. 43, (4), October 2019, p. 517-526
Huang, Yun; Kwan, Kin Leung; Leung, Ka Wing; Yao, Ping; Wang, Huaiyou; Dong, Tingxia; Tsim, Karl Wah Keung
Jasmonate-Elicited Stress Induces Metabolic Change in the Leaves of Leucaena leucocephala
Molecules, v. 23, (2), January 2018, article number 188
Xu, Yingchao; Tao, Zhenru; Jin, Yu; Chen, Shuangyan; Zhou, Zhongyu; Gong, Guowei; Yuan, Yunfei; Dong, Ting Xia; Tsim, Karl Wah Keung
Microphthalmia-associated transcription factor up-regulates acetylcholinesterase expression during melanogenesis of murine melanoma cells.
The Journal of Biological Chemistry, v. 293, (37), 2018, p. 14417-14428
Wu, Qiyun; Fung, Hei Yiu; Xu, Li; Poon, Ka Man; Liu, Yunle; Kong, Xiang Peng; Yao, Ping; Xiong, Q.P.; Dong, Tingxia; Tsim, Karl Wah Keung
Origin of Red Color in Edible Bird's Nests Directed by the Binding of Fe Ions to Acidic Mammalian Chitinase-like Protein
Journal of Agricultural and Food Chemistry, v. 66, (22), June 2018, p. 5644-5653
Wong, Chun Fai; Chan, Kar Lun Gallant; Dong, Ting Xia; Tsim, Karl Wah Keung
Prenylated Flavonoids from Roots of Glycyrrhiza uralensis Induce Differentiation of B16-F10 Melanoma Cells
International Journal of Molecular Sciences, v. 19, (8), 16 August 2018, article number 2422
Zheng, Yunfeng; Wang, Huaiyou; Yang, Min; Peng, Guoping; Dong, Tingxia; Xu, Li; Tsim, Karl Wah Keung
Quercetin Potentiates the NGF-Induced Effects in Cultured PC 12 Cells: Identification by HerboChips Showing a Binding with NGF
Evidence-based Complementary and Alternative Medicine, v. 2018, 2018, article number 1502457
Chan, Kar Lun Gallant; Hu, Weihui; Zheng, Xuan; Huang, M.; Lin, Xuyan; Wang, Yang; Gong, Guowei; Yang, X. Y.; Tsim, Karl Wah Keung; Dong, Tingxia
Searching for Active Ingredients in Edible Bird’s Nest
Journal of Complementory Medicine and Alternative Healthcare, v. 6, (2), May 2018, p. 1-5
Chan, Kar Lun Gallant; Wu, Kevin Q.Y.; Fung, Aster H.Y.; Poon, Karmen K M.; Wang, Caroline Y.W.; Gridneva, Elizaveta; Huang, Rena R.H.; Fung, Sisley Y.Z.; Xia, Y.T.; Hu, Winnie W.H.; Wong, Chun Fai Zack; Tsim, Karl Wah Keung
Surveillance of Drug Abuse in Hong Kong by Hair Analysis Using LC-MS/MS
Drug Testing and Analysis, v. 10, (6), June 2018, p. 977-983
Leung, Ka Wing; Wong, Chun Fai; Ho, Yuen Man; Yip, Wan Suet; Cheung, Ka Hei; Ho, Ka Lam Karen; Duan, Ran; Tsim, Karl Wah Keung
The Extract of Polygoni Cuspidati Rhizoma et Radix Suppresses the Vascularendothelial Growth Factor-induced Angiogenesis
Phytomedicine, v. 42, March 2018, p. 135-143
Hu, Wei Hui; Chan, Kar-Lun Gallant; Lou, Jian-Shu; Wu, Qi-Yun; Wang, Huai-You; Duan, Ran; Cheng, Michael Yu-Tung; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung
The extracts and major compounds derived from astragali radix alter mitochondrial bioenergetics in cultured cardiomyocytes: Comparison of various polar solvents and compounds
International Journal of Molecular Sciences, v. 19, (6), January 2018, article number 1574
Huang, Yun; Kwan, Kin Leung; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiang Peng; Dong, Ting Xia; Tsim, Karl Wah Keung
The WT1/MVP-mediated stabilization on mTOR/AKT Axis enhances the effects of cisplatin in non-small cell lung cancer by a reformulated Yu Ping Feng San herbal preparation
Frontiers in Pharmacology, v. 9, (AUG), August 2018, article number 853
Lou, Jianshu; Xia, Yiteng; Wang, Huaiyou; Kong, Xiangpeng; Yao, Ping; Dong, Tingxia; Zhou, Zhongyu; Tsim, Karl Wah Keung
The Yin-Yang Property of Chinese Medicinal Herbs Relates to Chemical Composition but Not Anti-Oxidative Activity: An Illustration Using Spleen-Meridian Herbs
Frontiers in Pharmacology, v. 9, November 2018, article number 1304
Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiang Peng; Wang, Long; Dong, Ting Xia; Chen, Yicun; Tsim, Karl Wah Keung
健妇胶囊对雌激素、孕激素和促红细胞生成素水平的影响
中药新药与临床药理=Traditional Chinese Drug Research and Clinical Pharmacology, v. 2018, (4), 2018, p. 428-432
董婷霞; 姚娉; 宫帼唯; 詹华强
Conference paper 23
Acetylcholinesterase regulates inflammatory responses in cultured macrophages: a player in cholinergic anti-inflammatory pathway
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Liu, Yunle; Xu, Li; Kong, Xiang P; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung
Alkaloids derived from traditional Chinese medicine are inhibitors for inflammation and acetylcholinesterase
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Kong, Xiang Peng; Xu, Li; Liu, Yunle; Wu, Qiyun; Dong, Tingxia; Wan, David CC; Tsim, Karl Wah Keung
Applications of edible bird’s nest (EBN) in cosmetics development
10th International Conference on Skin Ageing and Challenges, Portugal, 25-27 February 2018
Chan, Kar Lun Gallant; Wong, Chun Fai; Wu, Qiyun; Fung, Hei Yiu; Poon, Ka Man; Gridneva, Elizaveta; Xia, Yiteng; Dong, Tingxia; Tsim, Karl Wah Keung
Assembly of PRiMA-linked form of acetylcholinesterase in neurons: the role of enzyme inhibitor acting as chemical chaperon
13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Tsim, Karl Wah Keung; Liu, Yunle; Xu, Li; Kong, Xiang P; Wu, Qiyun; Duan, Ran; Dong, Tingxia
Comparison of the thermoregulatory effects of spleen-meridian herbs with different herbal properties on yeast induced animal model
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huai-you; Kong, Xiang-Peng; Dong, Tingxia; Chen, Yi-Cun; Tsim, Karl Wah Keung
Compatibility study of Danggui Buxue Tang and its chemical ingredients, a simple Chinese herbal decoction prepared from Astragali Radix and Angelicae Sinensis Radix, triggers the expression of neurotropic erythropoietin in cultured NTERA-2 neuron cell model
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Kwan, Kin Leung; Liang, Yanting; Fung, Yun Zhen; Dong, Tingxia; Tsim, Karl Wah Keung
Corylin induced the differentiation, mineralization and metabolic activity in rat osteoblasts and micromass cultures
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Yu, Xiaodan; Xu, Li; Yao, Ping; Dai, Kun; Dong, Tingxia; Ko, Kam Ming; Tsim, Karl Wah Keung
Danggui Buxue Tang, an ancient Chinese herbal decoction, protects β-amyloid-induced cell death in cultured cortical neurons
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Gong, Guowei; Dai, Kun; Duan, Ran; Dong, Tingxia; Wang, Huai-You; Tsim, Karl Wah Keung
Evidence-based Advanced Personalized Skincare Treatment of SGC Technology with Regeneration, Whitening and Antiageing Properties
The 10th International Conference on Skin Ageing and Challenges, Portugal, 25-27 February 2018
Fung, Hei Yiu; Poon, Ka Man; Chan, Kar Lun Gallant; Wu, Qiyun; Dong, Tingxia; Tsoi, Wai Ki Vickie; Tsoi, Venice; Tsim, Karl Wah Keung
Generation of digested products from edible bird’s nest (EBN): development of products for skin whitening
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Chan, Kar Lun Gallant; Wu, Qiyun; Poon, Ka Man; Xiong, Qing-Ping; Dong, Tingxia; Tsim, Karl Wah Keung
Genistein, a phytoestrogen in soybean, induces the expression of acetylcholinesterase via G protein-coupled receptor 30 in PC12 cells
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 09-14 September 2018
Liu, Yunle; Xu, Li; Wu, Qiyun; Dong, Tingxia; Chen, Sibao; Tsim, Karl Wah Keung
Indication of vascular endothelial growth factor (VEGF) binding components from extracts of Ginkgo Folium by Herbochips: a platform for drug screening on a chip
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Hu, Weihui; Wang, Huai-You; Duan, Ran; Xiong, Qing-Ping; Xia, Yi-Teng; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung
Isoorientin derived from Gentiana veitchiorum flower inhibits melanogenesis through down-regulating the expression of microphthalmia-associated transcription factor and tyrosinase
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Wu, Qiyun; Chan, Kar Lun Gallant; Dai, Kun; Kong, Xiang-Peng; Wang, Huai-You; Chen, Yi-Cun; Dong, Tingxia; Tsim, Karl Wah Keung
Isoorientin deriving from Gentiana veitchiorum flower inhibits melanogenesis through down-regulating the expression of microphthalmia-associated transcription factor and tyrosinase
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Wu, Qiyun; Chan, Kar Lun Gallant; Fung, Hei Yiu; Kong, Xiang-Peng; Wang, Huaiyou; Dong, Tingxia; Tsim, Karl Wah Keung
Microphthalmia-associated transcription factor regulates acetylcholinesterase expression during melanogenesis of B16F10 cells: a cholinergic regulator in pigmentation
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Wu, Qiyun; Fung, Hei Yiu; Xu, Li; Liu, Yunle; Duan, Ran; Yao, Ping; Dong, Tingxia; Tsim, Karl Wah Keung
Phytoestrogen induces the expression of acetylcholinesterase via G protein-coupled receptor 30 in cultured PC12 cells
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Liu, Yunle; Xu, Li; Kong, Xiang-Peng; Dai, Kun; Wu, Qiyun; Dong, Tingxia; Tsim, Karl Wah Keung
Polydatin suppresses the vascular endothelial growth factor (VEGF)-induced angiogenesis through binding with VEGF and inhibiting its receptor signaling
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Hu, Weihui; Wang, Huaiyou; Kong, Xiang-Peng; Duan, Ran; Chan, Kar Lun Gallant; Dong, Tingxia; Tsim, Karl Wah Keung
Regulation of Acetlcholinesterase via a cAMP-Dependent Pathway During Melanogenesis in Human Skin Cell
10th International Conference on Skin Ageing and Challenges, Portugal, 25-27 February 2018
Wu, Qiyun; Chan, Kar Lun Gallant; Fung, Hei Yiu; Poon, Ka Man; Dong, Tingxia; Tsim, Karl Wah Keung
Stimulatory effects of corylin on differentiation, mineralization and metabolic activity in rat osteoblasts and micromass cultures
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Yu, Xiaodan; Xu, Li; Yao, Ping; Dong, Tingxia; Ko, Kam Ming; Tsim, Karl Wah Keung
Study on the correlation between “Yin-Yang” nature of spleen-meridian herbs with the chemical composition, antioxidant activity and effects to energy metabolism
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, Hong Kong, 16-17 August 2018
Huang, Yun; Yao, Ping; Leung, Ka Wing; Wang, Huaiyou; Kong, Xiang-Peng; Dong, Tingxia; Tsim, Karl Wah Keung
The antibacterial effects of non-medicinal part of Scutellaria baicalnsis and potential application as an additive in aquaculture feedings
International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2018: Inheritance and Innovation - In Commemoration of the 500th Anniversary of the Birth of Li Shizhen, Hong Kong, 16-17 August 2018
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huaiyou; Dong, Tingxia; Kong, Xiang-peng; Tsim, Karl Wah Keung
The antibacterial effects of non-medicinal part of Scutellaria baicalnsis and potential application as an additive in aquaculture feedings
The 6th International Symposium on Edible & Medical Plant Resources and the Bioactive Ingredients, ISEPR2018, Nanjing, China, 14-17 October 2018
Xia, Yiteng; Chan, Kar Lun Gallant; Wang, Huai-You; Duan, Ran; Dong, Tingxia; Kong, Xiang-Peng; Tsim, Karl Wah Keung
Wnt3a induces the transcription of acetylcholinesterase: an enzyme playing a role in osteoblastic differentiation
The 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Czech Republic, 9-14 September 2018
Xu, Li; Liu, Yunle; Wu, Qiyun; Duan, Ran; Dong, Tingxia; Tsim, Karl Wah Keung
Article 16
A modified Chinese herbal decoction (Kai-Xin-San) promotes NGF-induced neuronal differentiation in PC12 cells via up-regulating Trk A signaling
Frontiers in Cell and Developmental Biology, v. 5, (DEC), December 2017, article number 118
Yan, Lu; Wei, Min; Gong, Amy Guo-wei; Song, Pingping; Lou, Jianshu; Bi, Wenchuan; Xu, Li; Xiong, Aizhen; Dong, Ting Xia; Tsim, Karl Wah Keung
A Novel Combination of Four Flavonoids Derived from Astragali Radix Relieves the Symptoms of Cyclophosphamide-Induced Anemic Rats
FEBS Open Bio, v. 7, (3), 1 March 2017, p. 318-323
Zhang, Li Wendy; Gong, Guo-wei; Riaz, Kashif; Deng, Jun Y.; Ho, Chih M.; Lin, Huangquan; Dong, Ting Xia; Lee, Yi-Kuen; Tsim, Karl Wah Keung
A Review of Dietary Ziziphus Jujuba Fruit (Jujube): Developing Health Food Supplements for Brain Protection
Evidence - Based Complementary and Alternative Medicine, v. 2017, 2017, Article number 3019568
Chen, Jianping; Liu, Xiaoyan; Li, Zhonggui; Qi, Airong; Yao, Ping; Zhou, Zhongyu; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Asarone from Acori Tatarinowii Rhizome prevents oxidative stress-induced cell injury in cultured astrocytes: A signaling triggered by Akt activation
PLoS ONE, v. 12, (6), June 2017, article number 0179077
Lam, Kelly Yin Ching; Yao, Ping; Wang, Huaiyou; Duan, Ran; Dong, Tina T. X.; Tsim, Karl W. K.
Cancer Treatment by Using Traditional Chinese Medicine: Probing Active Compounds in Anti-multidrug Resistance During Drug Therapy
Current Medicinal Chemistry, v. 25, (38), 2018, p. 5128-5141
Lou, Jianshu; Yao, Ping; Tsim, Karl Wah Keung
Chemical Differentiation of Dendrobium officinale and Dendrobium devonianum by Using HPLC Fingerprints, HPLC-ESI-MS, and HPTLC Analyses
Evidence-Based Complementary and Alternative Medicine, v. 2017, 2017, article number 8647212
Ye, Zi; Dai, Jia-Rong; Zhang, Cheng-Gang; Lu, Ye; Wu, Lei-Lei; Gong, Amy Guo-wei; Xu, Hong; Tsim, Karl Wah Keung; Wang, Zheng-Tao
Comparative Study of Different Acorus Species in Potentiating Neuronal Differentiation in Cultured PC12 Cells
PHYTOTHERAPY RESEARCH, v.31, (11), November 2017, p. 1757-1764
Lam, Yin Ching; Huang, Yun; Yao, Ping; Wang, Huai You; Dong, Ting Xia; Zhou, Zhongyu; Tsim, Karl W. K.
Danggui Buxue Tang (Astragali Radix and Angelicae Sinensis Radix) for menopausal symptoms: A review.
Journal of Ethnopharmacology, v. 199, March 2017, p. 205-210
Lin, Huang Quan; Gong, Amy Guo-wei; Wang, Huaiyou; Duan, Ran; Dong, Ting Xia; Zhao, Kui Jun; Tsim, Karl Wah Keung
Danggui Buxue Tang, a Simple Chinese Formula Containing Astragali Radix and Angelicae Sinensis Radix, Stimulates the Expressions of Neurotrophic Factors in Cultured Sh-sy5y Cells
Chinese Medicine, v. 12, (24), August 2017, article number 24
Gong, Amy Guo-wei; Wang, Huai You; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Zheng, Y. Z.
Ginkgetin Induces Autophagic Cell Death Through p62/SQSTM1- Mediated Autolysosome Formation and Redox Setting in Nonsmall Cell Lung Cancer
Oncotarget, v. 8, (54), October 2017, p. 93131-93148
Lou, Jianshu; Bi, Wenchuan; Chan, Kar Lun Gallant; Jin, Yan; Wong, Chau Wing; Zhou, Zhongyu; Wang, Huai You; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung
Identification of chemical constituents of Ophiopogon japonicus in Shenmai Injection
Chinese Traditional Patent Medicine, v. 2017, 11, 2017, p. 2340-2344
Li, Ning; Huang, Xing; Zhang, Jia-yu; Wang, Huaiyou; Dong, Tingxia; Tsim, Karl Wah Keung; Tu, Pengfei
Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway
Cellular and Molecular Neurobiology, v. 37, (4), May 2017, p. 655-664
Yu, Jie; Zheng, Jiacheng; Lin, Jiajia; Jin, Linlu; Yu, Rui; Mak, Shinghung; Hu, Shengquan; Sun, Hongya; Wu, Xiang; Zhang, Zaijun; Lee, Mingyuen; Tsim, Karl Wah Keung; Su, Wei; Zhou, Wenhua; Cui, Wei; Han, Yifan; Wang, Qinwen
Kai-Xin-San Series Formulae Alleviate Depressive-like Behaviors on Chronic Mild Stressed Mice via Regulating Neurotrophic Factor System on Hippocampus
Scientific Reports, v. 7, (1), December 2017, article number 1467
Zhu, Yue; Chao, Cheng; Duan, Xiuzhu; Cheng, Xiaoxuan; Liu, Pei; Su, Shulan; Duan, Jinao; Dong, Tina Tingxia; Tsim, Karl Wah-Keung
Polysaccharide of Danggui Buxue Tang, an Ancient Chinese Herbal Decoction, Induces Expression of Pro-inflammatory Cytokines Possibly Via Activation of NFκB Signaling in Cultured RAW 264.7 Cells
Phytotherapy Research, v. 31, (2), February 2017, p. 274-283
Gong, Amy Guo-Wei; Zhang, Minglu; Lam, Ting Wai; Xu, Miranda Li; Wang, Huai You; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
Wnt3a Induces the Expression of Acetylcholinesterase during Osteoblast Differentiation via the Runx2 Transcription Factor
Journal of Biological Chemistry, v. 292, (30), Jun 2017, p. 12667-12678
Xu, Miranda Li; Bi, Wenchuan; Liu, Yunle; Dong, Ting Xia; Tsim, Karl Wah Keung
参麦注射液中麦冬化学成分的鉴定
中成药=Chinese Traditional Patent Medicine, v. 39, (11), 2017, p. 2340-2344
李宁; 黄星; 王冰; 张加余; 王怀友; 董婷霞; 詹华强; 屠鹏飞
Conference paper 2
Acetylcholinesterase knock-out mice develop osteoporosis: a role of the globular form enzyme in osteoblastic differentiation
Journal of Neurochemistry, v. 142, (Supplement S2), August 2017, p. 204-204, Special issue on Cholinergic Mechanisms, Guest Editor: Israel Silman, Associate Guest Editors: Pascale Marchot and Marco Prado
Tsim, Karl Wah Keung; Bi, Wenchuan; Xu, Miranda Li; Liu, Yunle; Dong, Tingxia
Flavonoids induce the expression of acetylcholinesterase in cultured osteoblasts
Journal of Neurochemistry, v. 142, (Supplement S2), August 2017, p. 207-207, Special issue on Cholinergic Mechanisms, Guest Editor: Israel Silman, Associate Guest Editors: Pascale Marchot and Marco Prado
Bi, Wenchuan; Xu, Li; Liu, Yunle; Dong, Ting Xia; Tsim, Karl Wah Keung
Article 25
2,3,7,8-Tetrachlorodibenzo-P-Dioxin Suppress AChE Activity in NGF Treated PC12 Cells
Chemico-Biological Interactions, v. 259, November 2016, p. 282-285
Xu, Li; Chen, Yangsheng; Xie, Heidi Qun Hui; Xu, Tuan; Fu, Hualing; Zhang, Songyan; Tsim, Karl Wah Keung; Bi, Wenchuan; Zhao, Bin
A Chinese Herbal Decoction, Reformulated from Kai-Xin-San, Relieves the Depression-like Symptoms in Stressed Rats and Induces Neurogenesis in Cultured Neurons
Scientific Reports, v. 6, July 2016, article number 30014
Yan, Lu; Hu, Qinghua; Mak, Marvin S.H.; Lou, Jianshu; Xu, Li; Bi, Wenchuan; Zhu, Yue; Wang, Huai You; Dong, Ting Xia; Tsim, Karl Wah Keung
A High Throughput Screening Platform for Skin Tuning Properties from Natural Products: Identification of Skin Tanning Compounds
Journal of Cosmetics, Dermatological Sciences and Applications, v. 6, (5), December 2016, p. 199-209
Chan, Kar Lun Gallant; Wu, Qiyun; Wong, Chun Fai; Fung, Hei Yiu; Lin, Xuyan; Lou, Jianshu; Dong, Tingxia; Tsim, Karl Wah Keung
Anxiety and Depression with Neurogenesis Defects in Exchange Protein Directly Activated by cAMP 2-Deficient Mice are Ameliorated by a Selective Serotonin Reuptake Inhibitor, Prozac
Translational Psychiatry, v. 6, (9), September 2016, article number e881
Zhou, L.; Ma, Sukling; Yeung, Patrick Ka Kit; Wong, Yung Hou; Tsim, Karl Wah Keung; So, K. F.; Lam, L.C.W.; Chung, S.K.
Asarone from Acori Tatarinowii Rhizoma Potentiates the Nerve Growth Factor-Induced Neuronal Differentiation in Cultured PC12 Cells: A Signaling Mediated by Protein Kinase A
PLoS ONE, v. 11, (9), September 2016, article number e0163337
Lam, Yin Ching; Chen, Jianping; Lam, Ting Wai; Wu, Qiyun; Yao, Ping; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung
Authentication of Acori Tatarinowii Rhizoma (Shi Chang Pu) and its Adulterants by Morphological Distinction, Chemical Composition and ITS Sequencing
Chinese Medicine, v. 11, (1), September 2016, Article number 41
Lam, Yin Ching; Ku, Chuen Fai; Wang, Huai You; Chan, Kar Lun Gallant; Yao, Ping; Lin, Huang Quan; Dong, Ting Xia; Zhang, Hong Jie; Tsim, Karl Wah Keung
Badiranji Buya Keli, a Traditional Uyghur Medicine, Induces Vasodilation in Rat Artery: Signaling Mediated by Nitric Oxide Production in Endothelial Cells
Phytotherapy Research, v. 30, (1), January 2016, p. 16-24
Miernisha, Abudureyimu; Bi, Wenchuan; Cheng, Kwan Wai; Xing, J.G.; Liu, Jian; Maiwulanjiang, Maitinuer; Aisa, Haji Akber Kber; Dong, Ting Xia; Lin, Huangquan; Huang, Y.; Tsim, Karl Wah Keung
Chemical and biological assessment of Jujube (Ziziphus jujuba)-containing herbal decoctions: Induction of erythropoietin expression in cultures
Journal of Chromatography B, v. 1026, July 2016, p. 254-262
Lam, Ting Wai; Chan, Pui Hei; Lee, Pinky Sum-chi; Lau, Kei Man; Kong, Yeung Yeung Ava; Gong, Amy Guo-wei; Xu, Miranda Li; Lam, Yin Ching; Dong, Tingxia; Lin, Huangquan; Tsim, Karl Wah Keung
Clivorine, an Otonecine Pyrrolizidine Alkaloid from Ligularia Species, Impairs Neuronal Differentiation via NGF-Induced Signaling Pathway in Cultured PC12 Cells
Phytomedicine, v. 23, (9), August 2016, p. 931-938
Xiong, Aizhen; Yan, Artemis Lu; Bi, Wenchuan; Lam, Yin Ching; Chan, Kar Lun Gallant; Lau, Kei May; Dong, Ting Xia; Lin, Huangquan; Yang, Li; Wang, Zhengtao; Tsim, Karl Wah Keung
Danggui Buxue Tang, a Chinese Herbal Decoction, Induces Nitric Oxide Production in Cultured Endothelial Cells: Probing Calycosin as a Key Player by Chemical Knock-out Approach
Journal of Research and Development, March 2016, S1:1
Gong, Guowei; Lam, Ting Wai; Zhang, Minglu; Deng, Junyang; Wang, Huaiyou; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung
Danggui Buxue Tang, Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, Induces Production of Nitric Oxide in Endothelial Cells: Signaling Mediated by Phosphorylation of ndothelial Nitric Oxide Synthase
Planta medica, v. 82, (5), March 2016, p. 418-423
Gong, Amy Guowei; Lau, Keiman; Zhang, Minglu; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
Determination of hair ketamine cut-off value from Hong Kong ketamine users by LC-MS/MS analysis
Forensic Science International, v. 259, February 2016, p. 53-58
Leung, Ka Wing; Wong, Zack C.F.; Ho, Janet Y.M.; Yip, Ada W.S.; Ng, Jenny S.C.; Ip, Stanley P.H.; Ng, Winki Y.Y.; Ho, Karen K.L.; Duan, Ran; Zhu, Kevin Y.; Tsim, Karl Wah Keung
Expression of Globular form Acetylcholinesterase is not Altered in P2Y1R Knock-Out Mouse Brain
Chemico-Biological Interactions, v. 259, November 2016, p. 291-294
Cui, Di; Xu, Miranda Li; Liu, Yunle; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung; Bi, Wenchuan
Extract of Ziziphus jujuba Fruit (Jujube) Stimulates Expression of Enzymes Responsible for Heme Recycle via Anti-oxidant Response Element in Cultured Murine Macrophages
Phytotherapy Research, v. 30, (2), February 2016, p. 267-271
Chen, Jianping; Lam, Candy T.W.; Li, Zhonggui; Yao, Ping; Lin, Huangquan; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Ferulic Acid Orchestrates Anti-oxidation Properties of Danggui Buxue Tang, an Ancient Herbal Decoction: Elucidation by Chemical Knock-out Approach
PLoS ONE, v. 11, (11), November 2016, Article number e0165486
Gong, Amy Guo-wei; Huang, Yun; Wang, Huai You; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
Indication of Nerve Growth Factor Binding Components from Herbal Extracts by HerboChip: A Platform for Drug Screening on a Chip
Chinese Medicine, v. 11, (1), July 2016, article number 34
Lee, Pinky Sum-chi; Zhang, Minglu; Yan, Lu; Lam, Yin Ching; Dong, Ting Xia; Lin, Huangquan; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung
Jujube-containing herbal decoctions induce neuronal differentiation and the expression of anti-oxidant enzymes in cultured PC12 cells
Journal of Ethnopharmacology, v. 188, July 2016, p. 275-283
Lam, Ting Wai; Gong, Amy Guo-wei; Lam, Yin Ching; Zhang, Laura M.; Chen, Jian-Ping; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung
Kai-Xin-San, a Standardized Traditional Chinese Medicine Formula, Up-Regulates the Expressions of Synaptic Proteins on Hippocampus of Chronic Mild Stress Induced Depressive Rats and Primary Cultured Rat Hippocampal Neuron
Journal of Ethnopharmacology, v. 193, December 2016, p. 423-432
Zhu, Yue; Duan, Xiuzhu; Cheng, Xiaoxuan; Cheng, Xiaonan; Li, Xu; Zhang, Liu; Liu, Pei; Su, Shulan; Duan, Jinao; Dong, Ting Xia; Tsim, Karl Wah Keung; Huang, Fei
Kai-Xin-San, a Traditional Chinese Medicine Formula, Induces Neuronal Differentiation of Cultured PC12 Cells: Modulating Neurotransmitter Regulation Enzymes and Potentiating NGF Inducing Neurite Outgrowth
Journal of Ethnopharmacology, v. 193, December 2016, p. 272-282
Zhu, Yue; Duan, Xiuzhu; Huang, Feiyu; Cheng, Xiaonan; Zhang, Liu; Liu, Pei; Shulan, Su; Duan, Jinao; Dong, Tinatingxia; Tsim, Karl Wah Keung
Neuroprotection Against Glutamate-Induced Excitotoxicity and Induction of Neurite Outgrowth by T-006, a Novel Multifunctional Derivative of Tetramethylpyrazine in Neuronal Cell Models
Neurochemistry International, v. 99, October 2016, p. 194-205
Xu, Daping; Chen, Haiyun; Mak, Shinghung; Hu, Shengquan; Tsim, Karl Wah Keung; Hu, Yuanjia; Sun, Yewei; Zhang, Gaoxiao; Wang, Yuqiang; Zhang, Zaijun; Han, Yifan
New Perspectives for Multi-Level Regulations of Neuronal Acetylcholinesterase by Dioxins
Chemico-Biological Interactions, v. 259, November 2016, p. 286-290
Xie, Heidi Qun Hui; Xu, Tuan; Chen, Yangsheng; Li, Yunping; Xia, Yingjie; Xu, Sherry Li; Wang, Lingyun; Tsim, Karl Wah Keung; Zhao, Bin
Quantitative Analysis of Nucleosides and Nucleobases in Deer Antler: Variation in Different Species
Pharmaceutica Analytica Acta, v. 7, (4), April 2016, article number 1000474
Bi, Dan; Zhang, L.M.L.; Tang, Wai Lun; Duan, Ran; Leung, Ka Wing; Dong, Tingxia; Wong, Yung Hou; Lin, Huangquan; Tsim, Karl Wah Keung
The Estrogenic Properties Of Danggui Buxue Tang, A Chinese Herbal Decoction, Are Triggered Predominantly By Calycosin In Mcf-7 Cells
Journal of ethnopharmacology, v. 189, Aug 2016, p. 81-89
Gong, Amy Guo-wei; Lau, Kei Man; Xu, Miranda Li; Lin, Huangquan; Dong, Ting Xia; Zheng, Ken Y.Z.; Zhao, K.J.; Tsim, Karl Wah Keung
Transcriptional activity of acetylcholinesterase gene is regulated by DNA methylation during C2C12 myogenesis Transcriptional activity of acetylcholinesterase gene is regulated by DNA methylation during C2C12 myogenesis
Brain research, v. 1642, July 2016, p. 114-123
Lau, Kei Man; Gong, Amy Guowei; Xu, Miranda Li; Lam, Ting Wai; Zhang, Minglu; Bi, Wenchuan; Cui, Di; Cheng, Wai Ming Anthony; Dong, Ting Xia; Tsim, Karl Wah Keung; Lin, Huangquan
Yu Ping Feng San Reverses Cisplatin-induced Multi-drug Resistance in Lung Cancer Cells via Regulating Drug Transporters and p62/TRAF6 Signalling
Scientific Reports, v. 6, August 2016, article number 31926
Lou, Jianshu; Yan, Lu; Bi, Wenchuan; Chan, Kar Lun Gallant; Wu, Qiyun; Liu, Yunle; Huang, Yun; Yao, Ping; Du, Crystal Y.Q.; Dong, Ting Xia; Tsim, Karl Wah Keung
Book chapter 1
Chemical and Biological Assessment of Ziziphus jujuba (Jujubes) Fruit from China of Different Geographical Sources and Developmental Stages: Chemical Composition and Possible Targets in Developing Health Food Products
Chinese Dates: A Traditional Functional Food / Dongheng Liu, Xingqian Ye, Yueming Jiang, editors. Boca Raton : CRC Press - Taylor & Francis Group, 2016, p. 83-97
Chen, Jianping; Lam, Ting Wai; Li, Zhonggui; Yao, Ping; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung
Conference paper 11
Asarone from Acori Tatarinowii Rhizoma potentiates the nerve growth factor-induced neuronal differentiation in cultured PC12 cells: A signaling mediated by protein kinase A
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 12 August 2016
Lam, Yin Ching; Lin, Huangquan; Dong, Ting Xia; Yao, Ping; Lam, Ting Wai; Tsim, Karl Wah Keung
Authentication of Acori Tatarinowii Rhizoma and its adulterants: Morphological distinction, chemical composition and DNA analysis
China Medicinal Materials Resources Conference, Xian, China, August 2016
Tsim, Karl Wah Keung; Lam, Yin Ching; Wang, Huaiyou; Dong, Tingxia
Characterisation of spleen-meridian herbs using HPLC and UPLC/Q-TOF-MS ?ngerprints combined with principal component analysis
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, August 12th, 2016
Huang, Yun; Dong, Ting Xia; Yao, Ping; Zhou, Zhongyu; Lin, Huangquan; Tsim, Karl Wah Keung
Chemical and biological assessment of Ziziphus jujube fruits from China: different geographical sources and development stages
第五届可食和药用植物资源及功能成分国际学术研讨会, 深圳, 2016年11月4日至11月7日
Tsim, Karl Wah Keung
Chemical and biological assessment of Ziziphus jujube fruits from China: different geographical sources and development stages
China Medicinal Materials Resources Conference, Xian, China, 10 August, 2016
Tsim, Karl Wah Keung; Lam, Candy T.W.; Chen, Jianping; Zhou, Zhongyu; Gong, Guowei; Wang, Huaiyou; Yao, Ping; Duan, Ran
Erythropoietin (Epo)-induced Signaling is Interfered by Acetylcholinesterase (AChE) in Erythroblasts and Neurons
Journal of Neurochemistry, v. 142, August 2017, p. 214-215
Liu, Yunle; Dong, Ting Xia; Xu, Miranda Li; Bi, Wenchuan; Luk, Wilson K.W.; Tsim, Karl Wah Keung
Flavonoids Induce the Expression of Acetylcholinesterase in Cultured Osteoblasts
Chemico-Biological Interactions, v. 259, (B), 25 November 2016, p. 295-300
Xu, Miranda Li; Bi, Wenchuan; Kong, Yeung Yeung Ava; Dong, Ting Xia; Wong, Yung Hou; Tsim, Karl Wah Keung
Numerical Simulations of Electrochemical Impedance Spectroscopy of Polymer-based Micro Electrochemical Sensors for Rapid Identification of DNA Molecules from Traditional Chinese Medicine
8th International Symposium on Microchemistry and Microsystems (ISMM 2016), Hong Kong, 30 May-1 June 2016
Gao, Bo; Xu, Wei; Ma, Shenhui; Lee, Yi-Kuen; Tsim, Karl Wah Keung; Dong, Tingxia; Lam, Kelly Y.C.; Zhang, Anping
The Content of Arsenic (AS) in Cordyceps Sinensis
China Medicinal Materials Resources Conference, Xian, China, August 2016
Tsim, Karl Wah Keung; Dong, Tingxia; Duan, Ran; Tang, Wai Lun; Lam, Yin Ching
The osteogenic properties of Danggui Buxue Tang, a Chinese herbal decoction containing Astragali Radix and Angelicae Sinensis Radix: transcriptomics analysis of specific chemical knock-out herbal decoction
International Conference on DNA Technology for Authentication, Quality Control and Conservation of Herbal Material, The Chinese University of Hong Kong, 12 - 14 December, 2016
Gong, Amy G.W.; Dong, Tina Ting-xia; Tsim, Karl Wah Keung
Yu Ping Feng San, a Chinese herbal decoction, reverses cisplatin induced multi-drug resistance in non-small cell lung cancer
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, August 12th, 2016
Lou, Jianshu; Yao, Ping; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung
Article 18
Authentication of Cordyceps sinensis by DNA Analyses: Comparison of ITS Sequence Analysis and RAPD-Derived Molecular Markers
Molecules, v. 20, (12), December 2015, p. 22454-22462
Lam, Yin Ching; Chan, Kar Lun Gallant; Xin, Guizhong; Xu, Hong; Ku, Chuen Fai; Chen, Jianping; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
Calycosin orchestrates the functions of Danggui Buxue Tang, a Chinese herbal decoction composing of Astragali Radix and Angelica Sinensis Radix: An evaluation by using calycosin-knock out herbal extract
Journal of Ethnopharmacology, v. 168, June 2015, p. 150-157
Gong, Amy Guo-wei; Li, Ning; Lau, Kei Man; Lee, Pinky Sum-chi; Yan, Lu; Xu, Miranda Li; Lam, Ting Wai; Kong, Yeung Yeung Ava; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
Edible Bird’s Nest, an Asian Health Food Supplement, Possesses Skin Lightening Activities: Identification of N-Acetylneuraminic Acid as Active Ingredient
Journal of Cosmetics, Dermatological Sciences and Applications, v. 5, (4), November 2015, article number 61507, p. 262-274
Chan, Kar Lun Gallant; Wong, Chun Fai; Lam, Yin Ching; Cheng, Kwan Wai; Zhang, Minglu; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung
Evaluation of Hemostatic and Anti-inflammatory Activities of Extracts from Different Lagochilus Species in Experimental Animals: Comparison of Different Extractives and Sources
Phytotherapy Research, v. 29, (1), 2015, p. 22-29
Jiao, Ying; Chen, Pei-Hua; Xiong, Aizhen; Wang, Zheng-Tao; Tsim, Karl Wah Keung; Chou, Gui-Xin; Xu, Hong
Fast Simultaneous Determination of 13 Nucleosides and Nucleobases in Cordyceps sinensis by UHPLC-ESI-MS/MS
Molecules, v. 20, (12), December 2015, p. 21816-21825
Zong, Shiyu; Han, Han; Wang, Bing; Li, Ning; Dong, Ting Xia; Zhang, Tong; Tsim, Karl Wah Keung
Fruit of Ziziphus jujuba (Jujube) at Two Stages of Maturity: Distinction by Metabolic Profiling and Biological Assessment
Journal of Agricultural and Food Chemistry, v. 63, (2), January 2015, p. 739-744
Chen, Jianping; Chan, Pui Hei; Lam, Candy Ting Wai; Li, Zhonggui; Lam, Kelly Yin Ching; Yao, Ping; Dong, Tina Ting Xia; Lin, Huangquan; Lam, Henry H N; Tsim, Karl Wah Keung
Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β
Journal of Molecular Neuroscience, v. 57, (4), December 2015, p. 561-570
Hu, Shengquan; Cui, Wei; Zhang, Zaijun; Mak, Shinghung; Xu, Daping; Li, Gang; Hu, Yuanjia; Wang, Yuqiang; Lee, Mingyuen; Tsim, Karl Wah Keung; Han, Yifan
Inhibiting beta-Amyloid-Associated Alzheimer's Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue
Journal of Molecular Neuroscience, v. 55, (4), March 2015, p. 1014-1021
Hu, Shengquan; Wang, Rui; Cui, Wei; Zhang, Zaijun; Mak, Shinghung; Xu, Daping; Choi, Chunglit; Tsim, Karl Wah Keung; Carlier, Paul R.; Lee, Mingyuen; Han, Yifan
Optimizing the Compatibility of Paired-Herb in an Ancient Chinese Herbal Decoction Kai-Xin-San in Activating Neurofilament Expression in Cultured PC12 Cells
Journal of Ethnopharmacology, v. 162, March 2015, p. 155-162
Yan, Lu; Xu, Sherry L.; Zhu, Kevin Y.; Lam, Yin Ching; Xin, Guizhong; Maiwulanjiang, Maitinuer; Li, Ning; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung
Reduced Expression of P2Y2 Receptor and Acetylcholinesterase at Neuromuscular Junction of P2Y1 Receptor Knock-out Mice
Journal of Molecular Neuroscience, v. 57, (3), November 2015, p. 446-451
Xu, Miranda Li; Bi, Wenchuan; Cheng, Kwan Wai; Mak, Shinghung; Yao, Ping; Luk, Wilson K.W.; Lau, Kei May; Cheng, Anthony W.M.; Tsim, Karl Wah Keung
Robust Neuritogenesis-Promoting Activity by Bis(heptyl)-Cognitin Through the Activation of alpha7-Nicotinic Acetylcholine Receptor/ERK Pathway
CNS Neuroscience and Therapeutics, v. 21, (6), June 2015, p. 520-529
Hu, Sheng-Quan; Cui, Wei; Mak, Shing-Hung; Choi, Chung-Lit; Hu, Yuan-Jia; Li, Gang; Tsim, Karl Wah Keung; Pang, Yuan-Ping; Han, Yi-Fan
The Volatile Oil of Nardostachyos Radix et Rhizoma Induces Endothelial Nitric Oxide Synthase Activity in HUVEC Cells
PLoS ONE, v. 10, (2), February 2015, article number e0116761
Maiwulanjiang, Maitinuer; Bi, Wenchuan; Lee, Pinky Sum-chi; Xin, Guizhong; Miernisha, Abudureyimu; Lau, Kei May; Xiong, Aizhen; Li, Ning; Dong, Ting Xia; Aisa, Haji Akber Kber; Tsim, Karl Wah Keung
The water extract of Angelica Sinensis Radix protects cultured PC12 cells against oxidative stress: suppression of reactive oxygen species and activation of anti-oxidant response elements
Oxidants and Antioxidants in Medical Science, v. 4, (1), 2015, p. 39-48
Lee, Pinky Sum-Chi; Yan, Artemis Lu; Gong, Amy Guo-Wei; Choi, Roy Chi-Yan; Lin, Huang-Quan; Tsim, Karl Wah Keung
Three N-Glycosylation Sites of Human Acetylcholinesterase Shares Similar Glycan Composition
Journal of Molecular Neuroscience, v. 57, (4), December 2015, p. 486-491
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Keiman; Bi, Wenchuan; Cheng, Anthony W.M.; Gong, Amy Guo-wei; Lin, Huangquan; Tsim, Karl Wah Keung
Yu Ping Feng San, an Ancient Chinese Herbal Decoction, Induces Gene Expression of Anti-viral Proteins and Inhibits Neuraminidase Activity
Phytotherapy Research, v. 29, (5), May 2015, p. 656-661
Du, Crystal Ying Qing; Zheng, Ken Y.Z.; Bi, Wenchuan; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung
冬虫夏草中核苷类成分含量测定及HPLC指纹图谱研究
中药材=Journal of Chinese medicinal materials, v. 38, (5), May 2015, p. 952-956
王冰; 李宁; 董婷霞; 詹华强
浸泡和酸性物质促进硫熏山药脱硫的研究
中药材, v. 38, (2), 2015, p. 271-274
郑玉忠; 谢丽玲; 乐智勇; 贺震旦; 詹华强; 曹晖
硫熏山药对六味地黄丸中有效成分的影响
中国实验方剂学杂志=Chinese Journal of Experimental Traditional Medical Formulae, v. 21, (18), September 2015, p. 48-51
郑玉忠; 张振霞; 张勇; 刘亚群; 谢丽玲; 乐智勇; 贺震旦; 詹华强; 曹晖
Conference paper 12
Chemical And Biological Studies Of Chinese Date Decoctions
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Lam, C.T.W.; Gong, Amy Guo-wei; Lam, K.Y.C.; Dong, Ting Xia; Tsim, Karl Wah Keung
Comparison Of Different Authentication Methods On Acori Tatarinowii Rhizoma
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Lam, K.Y.C.; Chan, Kar Lun Gallant; Xin, G.Z.; Lam, C.T.W.; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
Cross‐talk of acetylcholinesterase with presenilin‐1
12th International Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12th ChE - PON6), Alicante, Spain, 27 September - 2 October 2015
Saez‐valero, Javier; Vidal, Cecilio J.; Campanari, Maria‐Letizia; Garcla‐ayllón, Maria‐Salud; Tsim, Karl Wah Keung
Establishment Of Quality Control Standard For Edible Bird's Nest By Monoclonal Antibodies And Fingerprint
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Wong, Z.C.F.; Chan, Kar Lun Gallant; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung
Expression of P2Y receptor and acetylcholinesterase in muscle and brain of P2Y1 knock-out mice
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Cui, Di; Bi, Wenchuan; Xu, Miranda Li; Lau, Kitty K.m.; Luk, Wilson K.w.; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
Functional and Quantitative PTM Proteomics in Study of Ethylene Signaling
11th Cross-straight Plant Biotechnology Symposium, Southern Central China Agricultural University. Wuhan, China, 2015
Li, Ning
Low-Cost Portable Polymer-based Micro Electrochemical Sensor (PMES) System for Rapid Detection of the Cordyceps Sinensis
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Chemical and Biological Microsystems Society (CBMS), 2015, p. 1734-1736
Ma, Shenhui; Riaz, Kashif; Maslova, Anastasia; Gao, Bo; Alsuhaimi, Awadh O.; Lam, Yin Ching; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Zhang, Anping; Lee, Yi-Kuen
Protective Functions Of Flavonoids In Nervous System Via Epo Regulation
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Zheng, Xuan; Bi, Wenchuan; Yao, Ping; Yan, Lu; Luk, Wilson K.W.; Dong, Ting Xia; Tsim, Karl Wah Keung
The bone morphogenetic protein 2 (BMP2)-induced downstream signalings are altered by globular form AChE in cultured osteoblasts
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Bi, Wenchuan; Xu, Miranda Li; Lau, Kitty K.M.; Cui, Di; Lin, Huangquan; Ip, Paul S.P.; Dong, Ting Xia; Tsim, Karl Wah Keung
The Effect of N-glycosylation on the Enzymatic Activity, Stability and Transportation of Acetylcholinesterase
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Kei Man; Bi, Wenchuan; Cui, Di; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
The N‐glycosylation of acetylcholinesterase regulates the enzymatic activity, stability and transport in a recombinant expression system
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Kitty K.M.; Bi, Wenchuan; Cui, Di; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
Transcriptional regulation of acetylcholinesterase in different cells
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonas, Elche, Spain, 27 September - 2 October 2015
Tsim, Karl Wah Keung; Luk, Wilson K.w.; Bi, Wenchuan; Yao, Ping; Lau, Kitty K.m.; Xu, Miranda Li; Cui, Di; Dong, Ting Xia
Article 27
A Chemically Standardized Extract of Ziziphus jujuba Fruit (Jujube) Stimulates Expressions of Neurotrophic Factors and Anti-oxidant Enzymes in Cultured Astrocytes
Phytotherapy Research, v. 28, (11), 2014, p. 1727-1730
Chen, Jianping; Yan, Artemis Lu; Lam, Kelly Yin Ching; Lam, Candy Ting Wai; Li, Ning; Yao, Ping; Xiong, Aizhen; Dong, Tingxia; Tsim, Karl Wah Keung
A Standardized Extract of the Fruit of Ziziphus jujuba (Jujube) Induces Neuronal Differentiation of Cultured PC12 Cells: A Signaling Mediated by Protein Kinase A
Journal of Agricultural and Food Chemistry, v.62, (8), 2014, Feb, p. 1890-1897
Chen, Jianping; Maiwulanjiang, Maitinuer; Lam, Yin Ching; Zhang, Wendyli; Zhan, Yaxian; Lam, Ting Wai; Xu, Li; Zhu, Kevin Yue; Yao, Ping; Lau, David Tai Wai; Dong, Tingxia; Tsim, Karl Wah Keung
Acetylcholinesterase Protein Level Is Preserved in the Alzheimer's Brain
Journal of Molecular Neuroscience, v. 53, (3), June 2014, p. 446-453
Campanari, Maria-Letizia; Garcia-Ayllon, Maria-Salud; Blazquez-Llorca, Lidia; Luk, Wilson K.W.; Tsim, Karl Wah Keung; Saez-Valero, Javier
Alkaloids of Linderae Radix Suppressed the Lipopolysaccharide-induced Expression of Cytokines in Cultured Macrophage RAW 264.7 cells
TANG: Humanitas Medicine, v. 4, (4), 2014
Chou, Jiyao; Lam, Yin Ching; Chen, Jianping; Yao, Ping; Dong, Tingxia; Xiong, Aizhen; Chou, Guixin; Wang, Zhengtao; Tsim, Karl Wah Keung
An application of target profiling analyses in the hepatotoxicity assessment of herbal medicines: comparative characteristic fingerprint and bile acid profiling of Senecio vulgaris L. and Senecio scandens Buch.-Ham
Analytical and Bioanalytical Chemistry, v. 406, (29), November 2014, p. 7715-7727
Xiong, Aizhen; Fang, Lianxiang; Yang, Xiao; Yang, Fan; Qi, Meng; Kang, Hong; Yang, Li; Tsim, Karl Wah Keung; Wang, Zhengtao
Characterizations of Cholinesterases in Golden Apple Snail (Pomacea canaliculata)
Journal of Molecular Neuroscience, v. 53, (3), 2014, p. 424-428
Zou, Xiang-Hui; Xie, Heidi Qun-Hui; Zha, Guang-Cai; Chen, Vicky Ping; Sun, Yan-Jie; Zheng, Yu-Zhong; Tsim, Karl Wah Keung; Dong, Tina Ting-Xia; Choi, Roy Chi-Yan; Luk, Wilson Kin-Wai
Ferulic acid enhances the chemical and biological properties of Astragali Radix: A stimulator for danggui buxue tang, an ancient chinese herbal decoction
Planta Medica, v. 80, (2-3), February 2014, p. 159-164
Zheng, Ken Yu Zhong; Zhang, Zhenxia; Du, Crystal Ying Qing; Zhang, Wendyli; Bi, Cathy Wen Chuan; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Functions of Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, in Uterus and Liver are Both Estrogen Receptor-Dependent and -Independent
Evidence-based Complementary and Alternative Medicine, v. 2014, 2014, article number 438531
Zierau, Oliver; Zheng, Ken Yuzhong; Papke, Anja; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Vollmer, Guenter
Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture
Evidence-based Complementary and Alternative Medicine, v. 2014, 2014, article number 608721
Zhang, Wendy Li; Chen, Jian-Ping; Lam, Kelly Yin-Ching; Zhan, Janis Ya-Xian; Yao, Ping; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung
Identification of Angelica oil as a suppressor for the biological properties of Danggui Buxue tang: A Chinese herbal decoction composes of Astragali Radix and Angelica Sinensis Radix
Journal of Ethnopharmacology, v. 154, (3), July 2014, p. 825-831
Zhan, Janis Ya-xian; Zheng, Ken Yu-zhong; Zhang, Wendy Li; Chen, Jian-ping; Yao, Ping; Bi, Cathy Wen-chuan; Dong, Tina Ting-xia; Tsim, Karl Wah Keung
Metabolomic and Genomic Evidence for Compromised Bile Acid Homeostasis by Senecionine, a Hepatotoxic Pyrrolizidine Alkaloid
Chemical Research in Toxicology, v. 27, (5), May 2014, p. 775-786
Xiong, Aizhen; Yang, Fan; Fang, Lianxiang; Yang, Li; He, Yuqi; Wan, Yvonne Yu-Jui; Xu, Ying; Qi, Meng; Wang, Xiuli; Yu, Kate; Tsim, Karl Wah Keung; Wang, Zhengtao
Metabonomic Analysis of Water Extracts from Different Angelica Roots by 1H-Nuclear Magnetic Resonance Spectroscopy
Molecules, v. 19, (3), 2014, p. 3460-3470
Chan, Pui Hei Nicholas; Zhang, Wendy L.; Lau, Chungho; Cheung, Chi Yuen; Keun, Hector C.; Tsim, Karl Wah Keung; Lam, Henry H N
Presenilin-1 Influences Processing of the Acetylcholinesterase Membrane Ancho PRiMA
Neurobiology of Aging, v. 35, (7), July 2014, p. 1526-1536
Garcia-Ayllon, Maria-Salud; Campanari, Maria-Letizia; Montenegro, Maria-Fernanda; Cuchillo-Ibanez, Inmaculada; Belbin, Olivia; Lleo, Alberto; Tsim, Karl Wah Keung; Vidal, Cecilio J.; Saez-Valero, Javier
Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by 1H-NMR Metabolic Profiling
Evidence-Based Complementary and Alternative Medicine, v. 2014, 2014, article number 567893
Chan, Pui Hei; Zhang, Wendy L.; Cheung, Chi Yuen; Tsim, Karl W.K.; Lam, Henry
Quantification of the Transcripts Encoding Different Forms of AChE in Various Cell Types: Real-Time PCR Coupled with Standards in Revealing the Copy Number
Journal of Molecular Neuroscience, v. 53, (3), July 2014, p. 461-468
Bi, Wenchuan; Luk, Wilson K.W.; Campanari, Maria-Letizia; Liu, Yuen H.; Xu, Li; Lau, Kei May; Xu, Miranda Li; Choi, Chi Yan; Saez-valero, Javier; Tsim, Karl Wah Keung
Rapid identification of plant materials by wooden-tip electrospray ionization mass spectrometry and a strategy to differentiate the bulbs of Fritillaria
Analytica Chimica Acta, v. 820, April 2014, p. 84-91
Xin, Guizhong; Hu, Bin; Shi, Zi Qi; Lam, Yin Ching; Dong, Ting Xia; Li, Ping; Yao, Zhong Ping; Tsim, Karl Wah Keung
Sunitinib Produces Neuroprotective Effect Via Inhibiting Nitric Oxide Overproduction
CNS Neuroscience and Therapeutics, v. 20, (3), March 2014, p. 244-252
Cui, Wei; Zhang, Zai-Jun; Hu, Sheng-Quan; Mak, Shing-Hung; Xu, Da-Ping; Choi, Chung-Lit; Wang, Yu-Qiang; Tsim, Karl Wah Keung; Lee, Ming-Yuen; Rong, Jian-Hui; Han, Yi-Fan
Synergistic Inhibition on Acetylcholinesterase by the Combination of Berberine and Palmatine Originally Isolated from Chinese Medicinal Herbs
Journal of Molecular Neuroscience, v. 53, (3), 2014, p. 511-516
Mak, Shinghung; Luk, Wilson W.K.; Cui, Wei; Hu, Shengquan; Tsim, Karl Wah Keung; Han, Yifan
The Extract of Ziziphus jujuba Fruit (Jujube) Induces Expression of Erythropoietin Via Hypoxia-Inducible Factor-1α in Cultured Hep3B Cells
Planta Medica, v. 80, (17), September 2014, p. 1622-1627
Chen, Jianping; Lam, Ting Wai; Kong, Yeung Yeung Ava; Zhang, Li Wendy; Zhan, Yaxian; Bi, Wenchuan; Chan, Kar Lun Gallant; Lam, Yin Ching; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung
The Standardized Extract of Ziziphus jujuba Fruit (Jujube) Regulates Pro-inflammatory Cytokine Expression in Cultured Murine Macrophages: Suppression of Lipopolysaccharide-stimulated NF-kappa B Activity
Phytotherapy research : PTR, v. 28, (10), October 2014, p. 1527-1532
Chen, Jianping; Du, Crystal Yingqing; Lam, Kelly Yin Ching; Zhang, Wendy L.; Lam, Candy Ting Wai; Yan, Artemis Lu; Yao, Ping; Lau, David Tai Wai; Dong, Tina Tingxia; Tsim, Karl Wah Keung
The sulfur-fumigation reduces chemical composition and biological properties of Angelicae sinensis radix
Phytomedicine, v. 21, (11), September 2014, p. 1318-1324
Zhan, Janis Ya-Xian; Yao, Ping; Bi, Cathy Wen-Chuan; Zheng, Ken Yu-zhong; Zhang, Wendy Li; Chen, Jian-Ping; Dong, Tina Ting-Xia; Su, Zi-Ren; Tsim, Karl Wah Keung
The volatile oil of Nardostachyos Radix et Rhizoma inhibits the oxidative stress-induced cell injury via reactive oxygen species scavenging and Akt activation in H9c2 cardiomyocyte
Journal of Ethnopharmacology, v. 153, (2), April 2014, p. 491-498
Maiwulanjiang, Maitinuer; Chen, Jianping; Xin, Guizhong; Gong, Amy G.W.; Miernisha, Abudureyimu; Du, Crystal Y.Q.; Lau, Keiman; Lee, Pinky S.C.; Chen, Jihang; Dong, Tina T.X.; Aisa, Haji A.; Tsim, Karl Wah Keung
UPLC-MS/MS法测定吸毒者头发中10种毒品代谢物的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 34, (3), 2014, p. 516-522
谢普; 王铁杰; 殷果; 闫研; 丁振浩; 肖丽和; 詹华强; 梁嘉荣; 李璐; 孙新珺; 毕开顺
Yu Ping Feng San, an Ancient Chinese Herbal Decoction, Regulates the Expression of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 and the Activity of Intestinal Alkaline Phosphatase in Cultures
PLoS ONE, v. 9, (6), June 2014, article number e100382
Du, Crystal Ying Qing; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David Tai Wai; Tsim, Karl Wah Keung
中药冬虫夏草的鉴别研究
中国药学杂志=Chinese Pharmaceutical Journal, v. 49, (4), February 2014, p. 283-286
徐红; 董婷霞; 赵奎君; 陈嘉伦; 林燕靖; 詹华强; 王峥涛
紫草药材的HPLC指纹图谱研究及其β-乙酰氧基异戊酰阿卡宁的含量测定
China Pharmacy, (3), 2014, p. 262-265
Miernisha, A.; Dong, Ting Xia; Guo, A.J.Y.; Aisa, HA; Tsim, Karl Wah Keung
紫草药材的HPLC指纹图谱研究及其β-乙酰氧基异戊酰阿卡宁的含量测定
中国药房=China Pharmacy, v. 25, (3), 2014, p. 262-265
米尔尼沙·阿不都热依木; 董婷霞; 郭江扬; 阿吉·艾克拜尔艾萨; 詹华强
Conference paper 9
Authenication of cervi cornu pantotrichum by microscopic and dna analysis
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Lam, Yin Ching; Xu, H.; Chan, Kar Lun Gallant; Xin, GZ; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung
Flavonoids originated from Chinese medicines possess neuroprotective effects on cultured neurons: Development of health food supplements in preventing Alzheimer's disease
Chinese Chemical Society 10th National Symposium on Natural Organic Chemistry, Guangzhou, China, 21-23 November 2014
Tsim, Karl Wah Keung
Optimizing the compatibility of paired-herb in an ancient chinses herbal decoction kai-xin-san in activating neurofilamment expression in cultured pc12 cells
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Yan, Lu; Xu, SL; Zhu, Kevin Y.; Lam, Yin Ching; Xin, GZ; Li, N.; Yao, Ping; Lin, Huangquan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Quality Control of Cooking Oils by GC-MS Profiling and Spectral Fingerprinting
62nd ASMS Conference on Mass Spectrometry and Allied Topics 2014, Baltimore, MD, USA, 15-19 June 2014
Chan, Pui Hei Nicholas; Zhu, Y.; Tsim, Karl Wah Keung; Lam, Henry H N
Resource development and biological evaluation: Nardostachyos Radix et Rhizoma and Dracocephali Moldavicae Herba
The 2014 International Seminar for Chinese Medicine & National Medical Resource and 11th Academic Annual Conference for Professional Committee of Natural Medicine Resource of China Society of National Resource, Nanjing, China, 15-18 October 2014
Tsim, Karl Wah Keung
The chemical and biological studies of zao tang and jujube extract
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Lam, Ting Wai; Chen, Jianping; Yan, Lu; Lam, Yin Ching; Chan, Pui Hei Nicholas; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
The pharmacological properties of calycosin-depleted danggui buxue tang
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Gong, Amy Guo-wei; Li, N.; Gao, QG; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung
The Quality Assurance of Edible Bird's Nest
Edible Bird Nest Industry Conference 2014, Putrajaya, Malaysia, 24-27 November 2014
Tsim, Karl Wah Keung
The role of flavonoids, derived from traditional chinese medicine, in the production of erythropoetin
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Men, WX; Xu, SL; Lin, HQ; Dong, TTX; Tsim, Karl Wah Keung
Article 28
Activation of UTP-Sensitive P2Y(2) Receptor Induces the Expression of Cholinergic Genes in Cultured Cortical Neurons: A Signaling Cascade Triggered by Ca2+ Mobilization and Extracellular Regulated Kinase Phosphorylation
Molecular Pharmacology, v. 84, (1), 2013, p. 50-61
Choi, Roy Chi Yan; Chu, Glanice K.Y.; Siow, Nina Lam; Yung, Amanda W.Y.; Yung, Lisa Ying; Lee, Pinky S.C.; Lo, Christopher C.W.; Simon, Joseph; Dong, Tina Ting Xia; Barnard, Eric A.; Tsim, Karl Wah Keung
Analysis of HPLC fingerprints and determination of isofraxidin and rosmarinic acid of Sarcandrae Herba from Sarcandra glabra (Thunb.) Nakai
China Pharmacy, v. 24, (47), 2013, p. 4472-4474
Tang, W.L.R.; Ng, Y.Y.; Bi, Dan; Duan, Ran; Tsim, Karl Wah Keung; Dong, Tina Ting Xia
Can Hedysari Radix replace Astragali Radix in Danggui Buxue Tang, a Chinese herbal decoction for woman aliment?
Phytomedicine, v. 20, (12), September 2013, p. 1076-1081
Zhang, Wendy Li; Choi, Roy Chi-Yan; Zhan, Janis Ya-Xian; Chen, Jian-Ping; Luk, Wilson Kin-Wai; Yao, Ping; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung
Chemical and Biological Assessment of Angelica Roots from Different Cultivated Regions in a Chinese Herbal Decoction Danggui Buxue Tang
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 483286
Zhang, Wendy L.; Zheng, Ken Y.Z.; Zhu, Kevin Y.; Zhan, Janis Y.X.; Bi, Cathy W.C.; Chen, J.P.; Dong, Tina T.X.; Choi, Roy C.Y.; Lau, David T.W.; Tsim, Karl W.K.
Chemical and Biological Assessment of Ziziphus jujuba Fruits from China: Different Geographical Sources and Developmental Stages
Journal of agricultural and food chemistry, v.61, (30), July 2013
Chen, Jianping; Li, Zhonggui; Maiwulanjiang, Maitinuer; Zhang, Wendy Li; Zhan, Janis Yaxian; Lam, Candy Ting Wai; Zhu, Kevin Yue; Yao, Ping; Choi, Chiyan; Lau, Taiwai; Dong, Tingxia; Tsim, Karl Wah Keung
Chemical changes of Angelicae Sinensis Radix and Chuanxiong Rhizoma by wine treatment: chemical profiling and marker selection by gas chromatography coupled with triple quadrupole mass spectrometry
Chinese Medicine (United Kingdom), v. 8, (1), June 2013, article number 12
Zhan, Janis Ya-Xian; Zhang, Wendy Li; Zheng, Ken Yu-zhong; Zhu, Kevin Yue; Chen, Jian-ping; Chan, Pui-Hei; Dong, Tina Ting-xia; Choi, Roy Chi-yan; Lam, Henry H N; Tsim, Karl Wah Keung; Lau, David Tai-wai
Chemical fingerprinting and quantitative analysis of two common Gleditsia sinensis fruits using HPLC-DAD
Acta Pharmaceutica, v. 63, (4), December 2013, p. 505-515
Chen, Jianping; Li, Zhonggui; Zheng, Ken Y.Z.; Guo, Ava J.Y.; Zhu, Kevin Y.; Zhang, Wendy L.; Zhan, Janis Y.X.; Dong, Tina T.X.; Su, Ziren; Tsim, Karl W.K.
Determination of free N-acetylneuraminic acid in edible bird nest: A development of chemical marker for quality control
Journal of Ethnobiology and Traditional Medicine, v. 120, October 2013, p. 620-628
Chan, Kar Lun Gallant; Zheng, Ken Yu Zhong; Zhu, Kevin Yue; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Distribution and expression of Kirre, an IgSF molecule, during postnatal development of rat cerebellum
Neuroscience Letters, v. 543, May 2013, p. 22-26
Kong, Lingwei; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Jing, Naihe; Nakayama, Don K.; Wang, Zhongbiao
Dual-Index Evaluation of Character Changes in Panax ginseng C. A. Mey Stored in Different Conditions
Journal of Agricultural and Food Chemistry, v. 61, (26), July 2013, p. 6568-6573
Li, Chen-yang; Lau, David Tai-wai; Dong, Tina Ting-xia; Zhang, Jian; Choi, Roy Chi-yan; Wu, Hai-qiang; Wang, Li-yan; Hong, Rui-sha; Li, Shi-he; Song, Xun; Yu, Tian; Su, Wei-wei; Tsim, Karl Wah Keung; He, Zhen-dan
Expression of cAMP-responsive Element Binding Proteins (CREBs) in Fast- and Slow-twitch Muscles: A Signaling Pathway to Account for the Synaptic Expression of Collagen-tailed Subunit (ColQ) of Acetylcholinesterase at the Rat Neuromuscular Junction
Chemico-biological Interactions, v. 203, (1), March 2013, p. 282-286
Choi, Roy Chi Yan; Chen, Ping; Luk, Wilson K.W.; Yung, Wai Yi; Ng, Alice H.M.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Flavonoids Induce the Expression of Synaptic Proteins, Synaptotagmin, and Postsynaptic Density Protein-95 in Cultured Rat Cortical Neuron
Planta Medica, v. 79, (18), December 2013, p. 1710-1714
Xu, Sherry Li; Zhu, Kevin Y; Bi, Wenchuan; Choi, Chi Yan; Miernisha, Abudureyimu; Yan, Artemis Lu; Maiwulanjiang, Maitinuer; Men, Simon W.X.; Dong, Ting Xia; Tsim, Karl Wah Keung
Flavonoids Induce the Synthesis and Secretion of Neurotrophic Factors in Cultured Rat Astrocytes: A Signaling Response Mediated by Estrogen Receptor
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013-06, article number 127075
Xu, Li; Bi, Wenchuan; Choi, Chi Yan; Zhu, Kevin Y; Miernisha, Abudureyimu; Dong, Ting Xia; Tsim, Karl Wah Keung
Flavonoids, Derived from Traditional Chinese Medicines, Show Roles in the Differentiation of Neurons: Possible Targets in Developing Health Food Products
Birth Defects Research Part C: Embryo Today: Reviews, v. 99, (4), December 2013, p. 292-299
Xu, Li; Zhu, Kevin Y; Bi, Wenchuan; Yan, Lu; Men, Simon W.X.; Dong, Ting Xia; Tsim, Karl Wah Keung
HPLC法同时测定浮小麦中5-二十一烷基间苯二酚和亚油酸的含量
中国药房=China Pharmacy, v. 24, (3), 2013, p. 244-246
高明菊; 毕 丹; 孟 霜; TANG Wai-lun; 徐 畅; 詹华强; 董婷霞
Importance of Wine-Treated Angelica Sinensis Radix in Si Wu Tang, a Traditional Herbal Formula for Treating Women's Ailments
Planta Medica, v. 79, (7), May 2013, p. 533-537
Zhan, Yaxian; Zheng, Ken Y.Z.; Zhu, Kevin Y; Zhang, Li Wendy; Bi, Wenchuan; Chen, Jianping; Du, Crystal Ying Qing; Dong, Ting Xia; Lau, David T W; Tsim, Karl Wah Keung
Kai-Xin-San, a Chinese Herbal Decoction Containing Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria, Stimulates the Expression and Secretion of Neurotrophic Factors in Cultured Astrocytes
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 731385
Zhu, Kevin Yue; Xu, Sherry Li; Choi, Roy Chi-Yan; Yan, Artemis Lu; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung
Optimizing Combinations of Flavonoids Deriving from Astragali Radix in Activating the Regulatory Element of Erythropoietin by a Feedback System Control Scheme
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 541436
Yu, Hui; Zhang, Wendy Li; Ding, Xianting; Zheng, Ken Yu Zhong; Ho, Chih-Ming; Tsim, Karl Wah Keung; Lee, Yi-Kuen
Perimenopause Amelioration of a TCM Recipe Composed of Radix Astragali, Radix Angelicae Sinensis, and Folium Epimedii: An In Vivo Study on Natural Aging Rat Model
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 747240
Su, Ji-Yan; Xie, Qing-Feng; Liu, Wei-Jin; Lai, Ping; Liu, Dan-Dan; Tang, Li-Hai; Dong, Tina Ting Xia; Su, Zi-Ren; Tsim, Karl Wah Keung; Lai, Xiao-Ping; Li, Kun-Yin
Song Bu Li Decoction, a Traditional Uyghur Medicine, Protects Cell Death by Regulation of Oxidative Stress and Differentiation in Cultured PC12 Cells
Evidence-Based Complementary and Alternative Medicine, v. 2013, 2013, article number 687958
Maiwulanjiang, Maitinuer; Zhu, Kevin Y.; Chen, Jianping; Abudureyimu miernisha; Xu, Li; Crystal y.q. du; Lau, Kei Man; Choi, Roy C.Y.; Dong, Tina T.X.; Aisa, Haji A.; Tsim, Karl W.K.
Surveillance of nitrite level in cubilose: Evaluation of removal method and proposed origin of contamination
Food Control, v. 34, (2), December 2013, p. 637-644
Chan, Gallant Kar Lun; Zhu, Kevinyue; Chou, David J.Y.; Guo, Ava Jiang Yang; Dong, Tinatingxia; Tsim, Karl Wah Keung
Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease
Evidence-Based Complementary and Alternative Medicine, v. 2013, 2013, article number 635694
Choi, Roy C.Y.; Zhu, Judy T.T.; Yung, Amanda W.Y.; Lee, Pinky S.C.; Xu, Sherry L.; Guo, Ava J.Y.; Zhu, Kevin Y.; Dong, Tina T.X.; Tsim, Karl W.K.
Yu Ping Feng San, an Ancient Chinese Herbal Decoction Containing Astragali Radix, Atractylodis Macrocephalae Rhizoma and Saposhnikoviae Radix, Regulates the Release of Cytokines in Murine Macrophages
PLoS ONE, v. 8, (11), November 2013, article number e78622
Du, Yingqing; Choi, Chi Yan; Zheng, Ken Yu Zhong; Dong, Ting Xia Tina; Lau, D.T.W.; Tsim, Karl Wah Keung
射干的质量标准研究
中国药房=China Pharmacy, v. 24, (11), 2013, p. 1023-1025
梁丽娟; 董婷霞; 詹华强; 赵奎君
山豆根急性毒性实验研究
时珍国医国药=Lishizhen Medicine and Materia Medica Research, (4), 2013, p. 771-773
王平; 吴熙; 李俊鹏; 谢天柱; 邬晓鸥; 王晓炜; 文屏; 詹华强; 李军
穿心莲质量标准研究
中国中医药信息杂志=Chinese Journal of Information on TCM, v. 20, (9), September 2013, p. 63-65
梁丽娟; 赵奎君; 董婷霞; 詹华强
肿节风药材的HPLC指纹图谱研究及其异嗪皮啶与迷迭香酸的含量测定
中国药房=China Pharmacy, v. 24, (47), 2013, p. 4472-4474
邓伟麟; 吴莹莹; 毕丹; 段然; 詹华强; 董婷霞
韭菜子的生药学研究
中国药房=China Pharmacy, v. 24, (3), 2013, p. 246-248
徐 红; 董婷霞; 林燕靖; 邓伟麟; 詹华强; 王峥涛
Article 17
A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats
Evidence-based complementary and alternative medicine, v. 2012, 2012, Article number 149256
Zhu, Kevin Yue; Mao, Qing-Qiu; Ip, Siu-Po; Choi, Roy Chi-Yan; Dong, Tina Ting-Xia; Lau, David Tai-Wai; Tsim, Karl Wah Keung
Acetylcholinesterase: old questions and new developments
Frontiers in Molecular Neuroscience, v.5, 2013, Jan
Tsim, Karl Wah Keung; Soreq, Hermona
Application of Complementary and Alternative Medicine on Neurodegenerative Disorders: Current Status and Future Prospects
Evidence-based complementary and alternative medicine, v.2012, 2012, Article number 930908
Ip, Paul Siu-Po; Tsim, Karl Wah Keung; Chan, Kelvin; Bauer, Rudolf
Chemical and biological assessment of Angelica herbal decoction: Comparison of different preparations during historical applications
Phytomedicine, v. 19, (11), August 2012, p. 1042-1048
Zhang, Li Wendy; Zheng, Ken Y Z; Zhu, Kevin Y; Zhan, Yaxian; Bi, Wenchuan; Chen, Jianping; Du, Y.; Zhao, Kuijun; Lau, David T W; Dong, Ting Xia; Tsim, Karl Wah Keung
Effect of a derived herbal recipe from an ancient Chinese formula, Danggui Buxue Tang, on ovariectomized rats
Journal of ethnopharmacology, v. 144, (3), December 2012, p. 567-575
Xie, Qing-Feng; Xie, Jian-Hui; Dong, Tina T.X.; Su, Ji-Yan; Cai, Da-Ke; Chen, Jian-Ping; Liu, Liang-Feng; Li, Yu-Cui; Lai, Xiao-Ping; Tsim, Karl Wah Keung; Su, Zi-Ren
Er Zhi Wan, an ancient herbal decoction for woman menopausal syndrome, activates the estrogenic response in cultured MCF-7 cells: An evaluation of compatibility in defining the optimized preparation method
Journal of ethnopharmacology, v. 143, (1), August 2012, p. 109-115
Xu, Hong; Su, Zi-Ren; Huang, Wen; Choi, Roy Chi-Yan; Zheng, Yu-Zhong; Lau, David Tai-Wai; Dong, Tina Ting-Xia; Wang, Zheng-Tao; Tsim, Karl Wah Keung
Fo Shou San, an Ancient Chinese Herbal Decoction, Protects Endothelial Function through Increasing Endothelial Nitric Oxide Synthase Activity
PLoS ONE, v. 7, (12), 2012, article no. e51670
Bi, Cathy W.C.; Xu, Li; Tian, Xiao Yu; Liu, Jian; Zheng, Ken Y.Z.; Lau, Chi Wai; Lau, David Tai Wai; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Huang, Yu; Tsim, Karl Wah Keung
HPLC-ELSD测定肉苁蓉及管花肉苁蓉中半乳糖醇含量
中国中医药信息杂志=Chinese Journal of Information on Traditional Chinese Medicine, v. 19, (8), 2012, p. 52-54
赵奎君; 梁丽娟; 毕丹; 董婷霞; 詹华强
Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor
Evidence-Based Complementary and Alternative Medicine, v. 2012, 2012 article number 278273
Xu, Sherry L.; Choi, Roy C.Y.; Zhu, Kevin Y.; Leung, Ka-Wing; Guo, Ava J.Y.; Bi, Dan; Xu, Hong; Lau, David T.W.; Dong, Tina T.X.; Tsim, Karl W.K.
Kaempferol as a flavonoid induces osteoblastic differentiation via estrogen receptor signaling
Chinese Medicine, v. 7, (10), April 2012
Guo, Ava Jiangyang; Choi, Roy Chiyan; Zheng, Ken Yuzhong; Chen, Vicky Ping; Dong, Tina Tingxia; Wang, Zheng-Tao; Vollmer, Günter; Lau, David Taiwai; Tsim, Karl Wah Keung
Metabonomic analysis of water extracts from Chinese and American ginsengs by H-1 nuclear magnetic resonance: identification of chemical profile for quality control
Chinese medicine, v. 7, November 2012, Article number 25
Chan, Pui Hei; Zheng, Ken Y.Z.; Tsim, Karl Wah Keung; Lam, Henry H N
Microfluidic chip based nano liquid chromatography coupled to tandem mass spectrometry for the determination of abused drugs and metabolites in human hair
Analytical and bioanalytical chemistry, v. 402, (9), March 2012, p. 2805-2815
Zhu, Kevin Yue; Leung, Ka Wing; Ting, Annie K.L.; Wong, Zack C.F.; Ng, Winki Y.Y.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wang, Tiejie; Lau, David Tai Wai; Tsim, Karl Wah Keung
N-linked glycosylation of dimeric acetylcholinesterase in erythrocytes is essential for enzyme maturation and membrane targeting
The FEBS journal, v. 279, (17), September 2012, p. 3229-3239
Luk, Wilson Kin Wai; Chen, Vicky Ping; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase
Neuroscience Letters, v. 523, (1), August 2012, p. 71-75
Chan, Wallace Kin Bon; Chen, Vicky Ping; Luk, Wilson K.W.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Salidroside Stimulates the Accumulation of HIF-1 Alpha Protein Resulted in the Induction of EPO Expression: A Signaling via Blocking the Degradation Pathway in Kidney and Liver Cells
European Journal of Pharmacology, v. 679, (1-3), March 2012, p. 34-39
Zheng, Ken Y Z; Zhang, Zhenxia; Guo, A.J.Y.; Bi, Wenchuan; Zhu, Kevin Y; Xu, Li; Zhan, Yaxian; Lau, David T W; Dong, Ting Xia; Choi, Chi Yan; Tsim, Karl Wah Keung
The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: A synergistic action of an ancient herbal decoction Danggui Buxue Tang
Journal of pharmaceutical and biomedical analysis, v. 70, 2012, p. 671-679
Zheng, Ken Yu Zhong; Choi, Roy Chi Yan; Guo, Ava Jiang Yang; Bi, Cathy Wei Chuan; Zhu, Kevin Yue; Du, Crystal Ying Qing; Zhang, Zhen Xia; Lau, David Tai Wai; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress
Journal of ethnopharmacology, v. 139, (1), 2012, p. 214-220
Wang, T.; Choi, Roy Chi Yan; Li, J.; Bi, Cathy Wei Chuan; Ran, W.; Chen, X.; Dong, Tina Ting Xia; Bi, K.; Tsim, Karl Wah Keung
Conference paper 14
A flavonol aglycone isorhamnetin possesses neuronal differentiation activity in PC12 cells via the potentiation of NGF on neurite outgrowth
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Xu, SL; Choi, Roy Chi Yan; Zhu, KY; Guo, AJY; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung
An ancient paired-herbal decoction Fo Shou San, stimulates the blood and circulation functions
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Bi, CWC; Xu, SL; Lau, David Tai Wai; Choi, RCY; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Blood circulation effect of Angelica Radix Sinensis: anti-platelet aggregation and ENTPD gene regulation in human endothelial cells
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Ng, AHM; Choi, RCY; Lau, DTW; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Characterization of Acetylcholinesterase in Oyster, Crassostrea Gigas
11th International Meeting on Cholinesterases, Russia, 2012
Dong, Ting Xia; Sit, BHM; Chen, VP; Chan, Kin Bon Wallace; Luk, WKW; Choi, Chi Yan; Tsim, Karl Wah Keung
Chromatographic fingerprint and determination of 5-heneicosylresorcinol and linoleic acid in Fructus Tritici Levis by HPLC
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Bi, Dan; Tang, RWL; Dong, Tina Ting Xia; Wang, ZT; Tsim, Karl Wah Keung
Dynamic change of flavonoids during the preparation of Danggui Buxue Tang: an outcome of moderate boiling of Chinese herbal mixture
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Zhang, WL; Zheng, KYZ; Zhu, KY; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Investigation on the bioactive compounds of Chinese dates at two stages of maturity from young or historical trees
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Cheng, JP; Guo, AJY; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung
Mechanistic study of Yu Ping Feng San-mediated the inhibition of intestinal P-glycoprotein efflux transporter to enhance the bioavailability of Astragali Radix-derived calycosin in Caco-2 cell monolayers
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Du, CYQ; Zheng, KYZ; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung
Molecular Assembly of Acetylcholinesterase-H Form in Erythrocyte
11th International Meeting on Cholinesterases, Russia, 2012
Luk, WKW; Chen, VP; Choi, RCY; Chan, WKB; Tsim, Karl Wah Keung
Neuroprotection effect of Angelica Sinensis Radix against oxidative stress in PC12 neurons
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Yung, AWY; Ng, AHM; Choi, RCY; Dong, Tina Ting Xia; Lau, DTW; Tsim, Karl Wah Keung
Studies on pharmacognosy of Lonicerae Japonicae Flos
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Lam, KYC; Dong, Tiina Ting Xia; Wong, ZT; Tsim, Karl Wah Keung
The study of the removal methods and the origin of nitrite in edible bird's nest
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Chan, GKL; Zheng, KYZ; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
The wine treatment on Angelicae Sinensis Radix and Chuanxiong Rhizoma: chemical distinction by using triple quadrupole gas chromatography
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, Chimna, 18-19 May 2012
Zhan, JYX; Zhang, WL; Zheng, KYZ; CHENG, JP; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung
Traditional Uyghur medicine - Song Bu Li, a decoction from Nardostachyos Radix et Rhizoma: development of quality control parameter and evaluation of the biological functions
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Maitinuer, M.; Choi, RCY; Aisa, HA; Lau, DTW; Dong, Tina Ting Xia; Wang, ZT; Tsim, Karl Wah Keung
Article 15
A Chinese Herbal Decoction, Danggui Buxue Tang, Stimulates Proliferation, Differentiation and Gene Expression of Cultured Osteosarcoma Cells: Genomic Approach to Reveal Specific Gene Activation
Evidence-based complementary and alternative medicine, (307548), 2011, p. 1-13
Choi, Roy Chi Yan; Gao, Qiu T.; Cheung, Anna Wing Han; Zhu, Judy Ting Ting; Lau, Faye T.C.; Li, Jun; Li, Winnie Z.M.; Chu, Glanice K.Y.; Duan, Ran; Cheung, Jerry K.H.; Ding, An W.; Zhao, Kui J.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Analysis of HPLC fingerprints of Fructus Aurantii from different habitats and contents of naringin, neohesperidin and synephrine
中国药学杂志, v. 46, (12), 2011, p. 955-959
Zhao, Kuijun; Zheng, Yuzhong; Dong, Tingxia; Tsim, Karl Wah Keung
Baicalin, a Flavone, Induces the Differentiation of Cultured Osteoblasts AN ACTION VIA THE Wnt/β-CATENIN SIGNALING PATHWAY
Journal of biological chemistry, v. 286, (32), August 2011, p. 27882-27893
Guo, Ava Jiang Yang; Choi, Roy Chi Yan; Cheung, Anna W.H.; Chen, Vicky Ping; Xu, Sherry Li; Dong, Tina Ting Xia; Chen, Ji J.; Tsim, Karl Wah Keung
Chemical and Biological Assessment of Angelicae Sinensis Radix after Processing with Wine: An Orthogonal Array Design To Reveal the Optimized Conditions
Journal of agricultural and food chemistry, v. 59, (11), June 2011, p. 6091-6098
Zhan, Janis Y.X.; Zheng, Ken Yu Zhong; Zhu, Kevin Yue; Bi, Cathy Wei Chuan; Zhang, Wendy L.; Du, Crystal Ying Qing; Fu, Qiang; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Lau, David Tai Wai
Chemical and DNA authentication of taste variants of Gynostemma pentaphyllum herbal tea
Food chemistry, v. 128, (1), September 2011, p. 70-80
Wu, Pui Kei; Tai, William C.S.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Zhou, Hua; Liu, Xin; Jiang, Zhi-Hong; Hsiao, W. L. Wendy
Expression of the IgSF protein Kirre in the rat central nervous system
Life sciences, v. 88, (13-14), 2011, p. 590-597
Kong, L.; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Wang, X.; Peng, G.; Xie, Z.; Tsim, Karl Wah Keung; Jing, N.
Flavonoids from Radix Astragali Induce the Expression of Erythropoietin in Cultured Cells: A Signaling Mediated via the Accumulation of Hypoxia-Inducible Factor-1α
Journal of Agricultural and Food Chemistry, v. 59, (5), 2011, p. 1697-1704
Zheng, Ken Y Z; Choi, Chi Yan; Cheung, Wing Han; Guo, A.J.Y.; Bi, Wenchuan; Zhu, Kevin Y; Fu, Qiang; Du, Yingqing; Zhang, Li Wendy; Zhan, Janis Y.X.; Duan, Ran; Lau, David T W; Dong, Ting Xia; Tsim, Karl Wah Keung
Fo Shou San, an ancient herbal decoction prepared from Angelicae Sinensis Radix and Chuanxiong Rhizoma, induces erythropoietin expression: A signaling mediated by the reduced degradation of hypoxia-inducible factor in cultured liver cells
Planta medica, v. 78, (2), November 2011, p. 122-127
Bi, Wenchuan; Xu, Li; Zhang, Li Wendy; Zhan, Yaxian; Fu, Qiang; Zheng, Ken Y Z; Chen, Ping; Lau, David T W; Choi, Chi Yan; Wang, Tiejie; Dong, Ting Xia; Tsim, Karl Wah Keung
Molecular Assembly and Biosynthesis of Acetylcholinesterase in Brain and Muscle: the Roles of t-peptide, FHB Domain, and N-linked Glycosylation
Frontiers in Molecular Neuroscience, v. 4, 2011, article number 36
Chen, Vicky P.; Luk, Wilson K.W.; Chan, Wallace K.B.; Leung, K. Wing; Guo, Ava J.Y.; Chan, Gallant K.L.; Xu, Sherry L.; Choi, Chi Yan; Tsim, Karl Wah Keung
Phenolic compounds from the rhizomes of dioscorea bulbifera
Chemistry & biodiversity, v. 8, (11), 2011, p. 2110-2116
Liu, Hai; Tsim, Karl Wah Keung; Chou, Guixin; Wang, Junming; Ji, Lili; Wang, Zhengtao
The Assembly of Proline-rich Membrane Anchor (PRiMA)-linked Acetylcholinesterase Enzyme GLYCOSYLATION IS REQUIRED FOR ENZYMATIC ACTIVITY BUT NOT FOR OLIGOMERIZATION
Journal of biological chemistry, v. 286, (38), September 2011, p. 32948-32961
Chen, Vicky P.; Choi, Roy C.Y.; Chan, Wallace K.B.; Leung, K. Wing; Guo, Ava J.Y.; Chan, Kar Lun Gallant; Luk, Wilson K.W.; Tsim, Karl Wah Keung
The establishment of a highly sensitive method in detecting ketamine and norketamine simultaneously in human hairs by HPLC-Chip-MS/MS
Forensic science international, v. 208, May 2011, p. 53-58
Zhu, Kevin Yue; Leung, Ka Wing; Ting, Annie K.L.; Wong, Zack Chun Fai; Fu, Qiang; Ng, Winki Y.Y.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wang, Tiejie; Lau, David Tai Wai; Tsim, Karl Wah Keung
The establishment of a sensitive method in determining different neurotransmitters simultaneously in rat brains by using liquid chromatography-electrospray tandem mass spectrometry
Journal of chromatography. B, v. 879, April 2011, p. 737-742
Zhu, Kevin Yue; Fu, Qiang; Leung, Ka Wing; Wong, Zack Chun Fai; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
The Extract of Rhodiolae Crenulatae Radix et Rhizoma Induces the Accumulation of HIF-1 alpha via Blocking the Degradation Pathway in Cultured Kidney Fibroblasts
Planta medica, v. 77, (9), June 2011, p. 894-899
Zheng, Ken Yu Zhong; Guo, Ava Jiang Yang; Bi, Cathy Wei Chuan; Zhu, Kevin Yue; Chan, Kar Lun Gallant; Fu, Qiang; Xu, Sherry Li; Zhan, Janis Y.Z.; Lau, David Tai Wai; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
不同产地枳壳药材HPLC指纹图谱及其柚皮苷、新橙皮苷和辛弗林含量分析
中国药学杂志=Chinese Pharmaceutical Journal, v. 2011, (12), 2011, p. 955-959
赵奎君; 郑玉忠; 董婷霞; 詹华强
Conference paper 1
1H-NMR metabonomics analysis of Danggui Buxue Tang effects in HEK293T kidney cell lines
China Human Proteome Organization (CNHUPO) 7th Annual Congress, Hangzhou, China, 2011
Chan, Pui Hei Nicholas; Tsim, Karl Wah Keung; Lam, Henry H N
Article 18
A Flavonol Glycoside, Isolated From Roots of Panax notoginseng, Reduces Amyloid-beta-Induced Neurotoxicity in Cultured Neurons: Signaling Transduction and Drug Development for Alzheimer's Disease
JOURNAL OF ALZHEIMERS DISEASE, v. 19, (3), 2010, p. 795-811
Choi, Roy Chi Yan; Zhu, Judy Ting Ting; Leung, Ka Wing; Chu, Glanice K.Y.; Xie, Heidi Qunhui; Chen, Vicky Ping; Zheng, Ken Yu Zhong; Lau, David Tai Wai; Dong, Tina Ting Xia; Chow, Peter C.Y.; Han, Yi-Fan; Wang, Zheng-Tao; Tsim, Karl Wah Keung
An induction effect of heat shock on the transcript of globular acetylcholinesterase in NG108-15 cells
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), 2010, SEP 6, p. 106-109
Chen, Vicky Ping; Xie, Heidi Qunhui; Chan, Wallace Kin Bon; Leung, Ka Wing; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Antihyperlipidemic Effect of Protodioscin, an Active Ingredient Isolated from the Rhizomes of Dioscorea nipponica
Planta Med., 76, 15, May 2010, p. 1642-1646
Wang, Tiejie; Choi, Chi Yan; Li, Jun; Bi, Wenchuan; Zang, Linquan; Liu, Zhongbo; Dong, Tingxia; Bi, Kaishun; Tsim, Karl Wah Keung
Anti-oxidative effects of the biennial flower of Panax notoginseng against H2O2-induced cytotoxicity in cultured PC12 cells
Chinese Medicine, v. 5, 2010
Choi, Roy Chi Yan; Jiang, Z.; Xie, Heidi Qunhui; Cheung, Anna Wing Han; Lau, David Tai Wai; Fu, Qiang; Dong, Tina Ting Xia; Chen, J.; Wang, Z.; Tsim, Karl Wah Keung
ATP induces synaptic gene expressions in cortical neurons: Transduction and transcription control via P2Y1 receptors
Molecular Pharmacology, v. 78, (6), 2010, p. 1059-1071
Siow, Nina Lam; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Kong, L.W.; Chu, G.K.Y.; Chan, Kar Lun Gallant; Simon, J.; Barnard, E.A.; Tsim, Karl Wah Keung
Differential gene expression profiling on the muscle of acetylcholinesterase knockout mice: A preliminary analysis
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), 2010, SEP 6, p. 120-123
Lin, Huang-Quan; Choi, Roy Chi Yan; Chan, Kam-Leung; Ip, Denis; Tsim, Karl Wah Keung; Wan, David Chi-cheong
Expression and Localization of PRiMA-Linked Globular Form Acetylcholinesterase in Vertebrate Neuromuscular Junctions
Journal of Molecular Neuroscience, v. 40, (1-2), January 2010, p. 40-46
Tsim, Karl Wah Keung; Leung, Ka Wing; Mok, Ka Wai; Chen, Ping; Zhu, Kevin Y; Zhu, Judy T T; Guo, A.J.Y.; Bi, Wenchuan; Zheng, Ken Y Z; Lau, David T W; Xie, Qunhui; Choi, Chi Yan
Fo Shou San, an Ancient Herbal Decoction Prepared from Rhizoma Chuanxiong and Radix Angelicae Sinensis, Stimulates the Production of Hemoglobin and Erythropoietin in Cultured Cells
Planta medica, v. 76, (14), October 2010, p. 1525-1529
Bi, Wenchuan; Xie, Qunhui; Xu, Li; Li, Jun; Cheung, Wing Han; Zhu, Judy T T; Zheng, Ken Y Z; Chen, Ping; Lau, David T W; Choi, Chi Yan; Wang, Tie Jie; Dong, Ting Xia; Tsim, Karl Wah Keung
Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), September 2010, p. 246-248
Guo, Ava Jiang Yang; Xie, Heidi Qunhui; Choi, Roy Chi Yan; Zheng, Ken Yu Zhong; Bi, Wenchuan; Xu, Sherry Li; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Nerve Growth Factor-Induced Differentiation of PC12 Cells Is Accompanied by Elevated Adenylyl Cyclase Activity
NeuroSignals, v. 18, (1), September 2010, p. 32-42
Yung, H.S.; Lai, K.H.; Chow, Kevin B.S.; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung; Wong, Yung Hou; Wu, Zhenguo; Wise, Helen
PRiMA directs a restricted localization of tetrameric AChE at synapses
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), September 2010, p. 78-83
Xie, Qunhui; Leung, Ka Wing; Chen, Ping; Chan, Kar Lun Gallant; Xu, Li; Guo, A.J.Y.; Zhu, Kevin Y; Zheng, Ken Y Z; Bi, Weichuan; Zhan, Yaxian; Chan, Kin Bon Wallace; Choi, Chi Yan; Tsim, Karl Wah Keung
Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae
Journal of Separation Science, v. 33, (23-24), 2010, p. 3666-3674
Zhu, Kevin Yue; Fu, Qiang; Xie, Heidi Qunhui; Xu, S.L.; Cheung, Anna Wing Han; Zheng, Ken Yu Zhong; Luk, W.K.W.; Choi, Roy Chi Yan; Lau, David Tai Wai; Dong, Tina Ting Xia; Jiang, Z.Y.; Chen, J.J.; Tsim, Karl Wah Keung
Quality Evaluation of Radix Glehniae (Glehnia littoralis) by HPLC-DAD: Chromatographic Fingerprinting and Quantitative Analysis of the Herbs from Different Regions of China
Asian Journal of Traditional Medicines 2010, v. 5, (2), 2010, p. 40-48
Li, Jun; Cheung, Wing Han; Bi, Wenchuan; Duan, Ran; Zheng, Ken Y Z; Huang, Wen; Chen, Ji J.; Dong, Ting Xia; Tsim, Karl Wah Keung
Synthesis and Anti-inflammatory Activity of a Novel Series of 9,10-Dihydro-4H,8H-chromeno [8,7-e][1,3]oxazin-4-one Derivatives
Chemical Research in Chinese Universities, v. 26, (2), 2010, MAR 25, p. 268-271
Liu, Xiao-ping; Wang, Ying; Lan, Hui-yu; Song, Ai-hua; Tsim, Karl Wah Keung; Dong Tina, Ting-xia; Hu, Chun
Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons
Journal of Biological Chemistry, v. 285 (15), pp. 11537-11546
Xie, Heidi Qunhui; Liang, Dong; Leung, Ka Wing; Chen, Vicky Ping; Zhu, Kevin Yue; Chan, Wallace Kin Bon; Choi, Roy Chi Yan; Massoulié, Jean; Tsim, Karl Wah Keung
The expression of erythropoietin triggered by Danggui Buxue Tang, a Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells
Journal of Ethnopharmacology, v. 132, (1), October 2010, p. 259-267
Zheng, Ken Y Z; Choi, Chi Yan; Xie, Qunhui; Cheung, Wing Han; Guo, A.J.Y.; Leung, Ka Wing; Chen, Ping; Bi, Weichuan; Zhu, Kevin Y; Chan, Kar Lun Gallant; Fu, Qiang; Lau, David T W; Dong, Ting Xia; Zhao, K.J.; Tsim, Karl Wah Keung
The PRiMA-linked cholinesterase tetramers are assembled from homodimers hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain
Journal of biological chemistry, v. 285, (35), 2010, AUG 27, p. 27265-27278
Chen, Vicky Ping; Xie, Heidi Qunhui; Chan, Wallace Kin Bon; Leung, Ka Wing; Chan, Kar Lun Gallant; Choi, Roy Chi Yan; Bon, Suzanne; Massoulie, Jean; Tsim, Karl Wah Keung
黄芪中7种活性成分对缺氧诱导因子(HIF-1)表达的影响
中国药房=China Pharmacy, v. 2010, (47), 2010, p. 4422-4424
梁丽娟; 董婷霞; 詹华强; 屠鹏飞; 赵奎君
Conference paper 17
"Female ginseng" – DANGGUI (当归): study on chemical profile after wine-processing
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Zhan, JYX; Zheng, KYZ; Bi, CWC; Zhu, KY; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
A new species of cholinesterase in chicken brain: PRiMA-linked AChE-BChE hybrid tetramer
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chen, VP; Chan, Kin Bon Wallace; Leung, Ka Wing; Zhang, VQ; Chan, GKL; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
A novel authentication method on edible bird nest by TripleQuad LC-MS/MS
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, XINJIANG CHINA, 2010
Chan, GKL; Li, J.; Wang, SH; Wang, TJ; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
A novel G-protein-coupled receptor complex: heterodimerization of purinergic P2Y1 and P2Y2 receptors
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chan, GKL; Leung, Ka Wing; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Acetylcholinesterase in erythrocytes: A non-cholinergic role in regulating erythropoiesis
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, 2010
Zhang, VQ; Chen, VP; Guo, AJY; Chan, GKL; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Aqueous extract of the root and rhizome of Rhodiola crenuclata induces the accumulation of HIF-1α via blocking the degradation pathway
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, , 2010
Zheng, KYZ; Guo, AJY; Bi, CWC; Zhu, KY; Xu, SL; Zhan, JYX; Chan, GKL; Cheung, Wing Han; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Authentication of dendrobium species by DNA sequencing method: clarification of the definition of Chinese pharmacopeia
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Chan, GKL; Jiang, ZW; Choi, Roy Chi Yan; Lau, David T W; Tsim, Karl Wah Keung
Combination of baicalein and daidzein synergistically enhanced the estrogenic and neuroprotective effects: drug development against Alzheimer's disease
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Guo, AJY; Xu, SL; Zheng, KYZ; Cheung, Wing Han; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Estrogenic and neuroprotective effects of baicalein and daizein: drug development against Alzheimer's disease
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Guo, AJY; Cheung, Wing Han; Zhu, KY; Zheng, KYZ; Xu, SL; Lau, David T W; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Fo Shou San, an ancient herbal decoction prepared from Angelica Sinensis Radix and Chuangxiong Rhizoma, stimulates the production of hemoglobin and erythropoietin in cultured cells
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang China, 2010
Bi, CWC; Xie, HQ; Xu, SL; Li, Jun; Cheung, Wing Han; Zheng, KYZ; Lau, DTW; Choi, Chi Yan; Wang, TJ; Dong, Ting Xia; Tsim, Karl Wah Keung
Investigation of KAI XIN SAN (开心散) and DING ZHI WAN (定志丸) – two traditional herbal formulae in treating mental disorder elucidation of action mechanism with chemical and biological methods
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, XINJIANG CHINA, 2010
Zhu, KY; Choi, Roy Chi Yan; Luk, WKW; Lau, David T W; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Neuroprotective and neurogenic effect of flavnoids derived from the traditional Chinese medicines
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Xu, SL; Guo, AJY; Cheung, Wing Han; Zhu, KY; Zheng, KYZ; Lau, David T W; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Objectives, delivery and assessment – adoption of the outcome-based education triangular philosophy and methodologies at the program level of a biology program
TARC International Conference on Learning and Teaching TIC2010, Tunku Abdul Rahman College, Malaysia, 18-19, Oct, 2010
Yu, L.; Siow, NL; Tsim, Karl Wah Keung; Chow, King Lau
Post-translational modification of PRiMA-linked G4 AChE by glycosylation
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chan, Kin Bon Wallace; Chen, VP; Leung, Ka Wing; Zhang, VQ; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Promoting students' personal development through biology co-curriculum in partnership with non-academic units
TARC International Conference on Learning and Teaching TIC2010, Tunku Abdul Rahman College, Malaysia. October 18-19, 2010
KO, IWP; Chow, King Lau; Ren, YY; Tsim, Karl Wah Keung
Tandem mass spectrometric analysis of triterpene saponins in Weilingxian (Roots and Rhizomes of Clematis chinensis) by RRLC-DAD-ESI-MSn
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang China, 2010
Fu, Q.; Zan, K.; Zhao, MB; Zhou, SX; Shi, SP; Tu, PF; Tsim, Karl Wah Keung
The optimization of wine-processing of Angelica Sinensis Radix via chemical assessment and GC-MS fingerprinting
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang, China, 2010
Zhan, JYX; Zheng, KYZ; Bi, CWC; Zhu, KY; Fu, Q.; Duan, Ran; Lau, David T W; Dong, Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Article 15
A new variant of proline-rich membrane anchor (PRiMA) of acetylcholinesterase in chicken: Expression in different muscle fiber types
Neuroscience Letters, v. 461, (2), 2009, SEP 11, p. 202-206
Mok, Mokka K.W.; Leung, Ka Wing; Xie, Heidi Qunhui; Guo, Ava Jiang Yang; Chen, Vicky Ping; Zhu, Judy Ting Ting; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Can Rhizoma Chuanxiong Replace Radix Angelica Sinensis in the Traditional Chinese Herbal Decoction Danggui Buxue Tang?
Planta medica, v. 75, (6), May 2009, p. 602-606
Li, W.Z.M.; Li, Jun; Bi, Wenchuan; Cheung, Anna Wing Hsn; Huang, Wen; Duan, Ran; Choi, Roy Chi Yan; Chen, Ivy S.Y.; Zhao, Kuijun; Dong, Ting Xia; Duan, Jin A.; Tsim, Karl Wah Keung
Cordysinocan, a Polysaccharide Isolated from Cultured Cordyceps, Activates Immune Responses in Cultured T-lymphocytes and Macrophages: Signaling Cascade and Induction of Cytokines
Journal of Ethnopharmacology, v. 124, (1), July 2009, p. 61-68
Cheung, Ka Hei; Li, Jun; Cheung, Wing Han; Zhu, Kevin Y; Zheng, Ken Y Z; Bi, Wenchuan; Duan, Ran; Choi, Chi Yan; Lau, David T W; Dong, Ting Xia; Lau, Brad W.C.; Tsim, Karl Wah Keung
Differential and Synergistic Effect of Nerve Growth Factor and cAMP on the Regulation of Early Response Genes during Neuronal Differentiation
NeuroSignals, v. 17, (2), May 2009, p. 111-120
Ng, Yu Pong; Wu, Zhenguo; Wise, Helen; Tsim, Karl Wah Keung; Wong, Yung Hou; Ip, Nancy Yuk-Yu
Effect of Extraction Solvent on the Bioactivity of an Herbal Formulation
Industrial and Engineering Chemistry Research, v. 48, (10), May 2009, p. 4852-4857
Chan, Kin N.; Lau, Choi C.; Chow, King Lau; Ko, Robert Kam Ming; Tsim, Karl Wah Keung; Ng, Ka Ming
Estrogenic and Neuroprotective Properties of Scutellarin from Erigeron breviscapus: A Drug against Postmenopausal Symptoms and Alzheimer's Disease
Planta medica, v. 75, (14), June 2009, p. 1489-1493
Zhu, Judy T T; Choi, Chi Yan; Li, Jun; Xie, Qunhui; Bi, Wenchuan; Cheung, Wing Han; Dong, Ting Xia; Jiang, Zhiyong; Chen, Jijun; Tsim, Karl Wah Keung
Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons
Neuroscience Letters, v. 461, (2), September 2009, p. 172-176
Zhu, Judy T T; Choi, Chi Yan; Xie, Qunhui; Zheng, Ken Y Z; Guo, A.J.Y.; Bi, Wenchuan; Lau, David T W; Li, Jun; Dong, Ting Xia; Lau, Brad W.C.; Chen, Ji J.; Tsim, Karl Wah Keung
HPLC法测定女贞子药材中女贞苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 29, (5), 2009, p. 824-826
黄雯; 苏子仁; 毕文川; 李军; 施丽琼; 文英强; 詹华强
HPLC测定当归补血片中黄芪甲苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 29, (9), 2009, p. 1553-1555
刘玮锦; 蔡大可; 刘亮锋; 赖平; 董婷霞; 詹华强; 苏子仁
Ligustilide Suppresses the Biological Properties of Danggui Buxue Tang: A Chinese Herbal Decoction Composed of Radix Astragali and Radix Angelica sinensis
Planta medica, v. 76, (5), October 2009, p. 439-443
Zheng, Ken Yu Zhong; Choi, Roy Chi Yan; Li, Jun; Xie, Heidi Qunhui; Cheung, Anna Wing Han; Duan, Ran; Guo, Ava Jiang Yang; Zhu, Judy Ting Ting; Chen, Vicky Ping; Bi, Wenchuan; Zhu, Kevin Yue; Lau, David Tai Wai; Dong, Tina Ting Xia; Lau, Brad Wing Chuen; Tsim, Karl Wah Keung
Quality Evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by Using High-performance Liquid Chromatography Coupled with Diode Array Detector and Mass Spectrometry
Journal of Chromatography A, v. 1216, (11), March 2009, p. 2071-2078
Li, Jun; Li, Winnie Z.M.; Huang, Wen; Cheung, Wing Han; Bi, Wenchuan; Duan, Ran; Guo, A.J.Y.; Dong, Ting Xia; Tsim, Karl Wah Keung
Restricted localization of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase at the neuromuscular junctions - contribution and expression from motor neurons
FEBS JOURNAL, v. 276, (11), 2009, JUN, p. 3031-3042
Leung, Ka Wing; Xie, Heidi Qunhui; Chen, Vicky Ping; Mok, Mokka K.W.; Chu, Glanice K.Y.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines
Chinese Medicine, v. 4, 2009
Guo, Ava Jiang Yang; Choi, Roy Chi-Yan; Cheung, Anna Wing Han; Li, Jun; Chen, Ivy X.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Lau, B.W.C.
Transcriptional regulation of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in neuron: An inductive effect of neuron differentiation
Brain research, v. 1265, 2009, APR 10, p. 13-23
Xie, Heidi Qunhui; Choi, Roy Chi Yan; Leung, Ka Wing; Chen, Vicky Ping; Chu, Glanice K.Y.; Tsim, Karl Wah Keung
Two new compounds from the roots of Ligusticum chuanxiong
Journal of Asian natural products research, v. 11, (9), 2009, p. 805-810
Chang, Xin-Liang; Jiang, Zhi-Yong; Ma, Yun-Bao; Zhang, Xue-Mei; Tsim, Karl Wah Keung; Chen, Ji-Jun
Conference paper 4
A novel non-cholinergic function of acetylcholinesterase: osteogenic effect in cultured osteocarcoma MG-63 cells
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Sociey of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Guo, A.J.Y.; Zhu, Judy T T; Zheng, Ken Y Z; Bi, Wenchuan; Xie, Qunhui; Tsim, Karl Wah Keung
Identification and characterization of splice variants of Proline Rich Membrane Anchor (PRiMA) of acetylcholinesterase (AChE) in different muscle fiber types in chicken
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Society of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Mok, Ka Wai; Chen, Ping; Chu, Kin Yan; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung
Quality control of ginseng by 1H NMR metabolic profiling
International Conference on Resource Development of Chinese Medicines from Northwestern China, Hong Kong, China, 2009
Chan, Pui Hei Nicholas; Choi, Chi Yan; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung; Lam, Henry H N
The molecular assembly of acetylcholinesterase and butyrylcholinesterase: the formation of PRiMA-linked G4 hybrid
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Society of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Chen, Ping; Xie, Qunhui; Leung, Ka Wing; Choi, Chi Yan; Tsim, Karl Wah Keung
Article 8
A chinese herbal decoction prepared from radix astragali and radix angelicae sinensis induces the expression of erythropoietin in cultured Hep3B cells
Planta medica, v. 74, (4), 2008, MAR, p. 392-395
Gao, Qiu T.; Cheung, Jerry K.H.; Choi, Roy Chi Yan; Cheung, Anna Wing Han; Lv, Jun; Jiang, Zhi Y.; Duan, Ran; Zhao, Kui J.; Ding, An W.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Constitutive and agonist-induced dimerizations of the P2Y(1) receptor - Relationship to internalization and scaffolding
Journal of biological chemistry, v. 283, (16), 2008, APR 18, p. 11050-11063
Choi, Roy Chi Yan; Simon, Joseph; Tsim, Karl Wah Keung; Barnard, Eric A.
Myocyte enhancer factor 2 mediates acetylcholine-induced expression of acetylcholinesterase-associated collagen ColQ in cultured myotubes
MOLECULAR AND CELLULAR NEUROSCIENCE, v. 39, (3), October 2008, p. 429-438
Lau, Faye T.C.; Choi, Chi Yan; Xie, Qunhui; Leung, Ka Wing; Chen, Ping; Zhu, Judy T T; Bi, Weichuan; Chu, Glanice K.Y.; Tsim, Karl Wah Keung
Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity
Biochemical and biophysical research communications, v. 366, (3), 2008, FEB 15, p. 631-636
Fu, Hongjun; Li, Wenming; Luo, Jialie; Lee, Nelson T.K.; Li, Mingtao; Tsim, Karl Wah Keung; Pang, Yuanping; Youdim, Moussa B.H.; Han, Yifan
Regulation of PRiMA-linked G(4) AChE by a cAMP-dependent signaling pathway in cultured rat pheochromocyoma PC12 cells
Chemico-biological interactions, v. 175, (1-3, Sp. Iss. SI), 2008, SEP 25, p. 76-78
Choi, Roy Chi Yan; Mok, Mokka K.W.; Cheung, Anna Wing Han; Siow, Nina Lam; Xie, Heidi Qunhui; Tsim, Karl Wah Keung
Special Issue: Proceedings of the IXth International Meeting on Cholinesterases Preface
Chemico-biological interactions, v. 175, September 2008, p. 1-2
Doctor, Bhupendra P.; Tsim, Karl Wah Keung; Siow, Nina L.
The promoter activity of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in muscle: Suppressive roles of myogenesis and innervating nerve
Chemico-biological interactions, v. 175, (1-3, Sp. Iss. SI), 2008, SEP 25, p. 79-82
Xie, Heidi Qunhui; Leung, Ka Wing; Chen, Vicky Ping; Lau, Faye T.C.; Liu, Lois S.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Transcriptional Control of Different Subunits of AChE in Muscles: Signals Triggered by the Motor Nerve-derived Factors
Chemico-biological interactions, v. 175, (1-3), September 2008, p. 58-63
Tsim, Karl Wah Keung; Choi, Chi Yan; Xie, Qunhui; Zhu, Judy T T; Leung, Ka Wing; Lau, Faye T.C.; Chu, Glanice K.Y.; Chen, Ping; Mok, Mokka K.W.; Cheung, Wing Han; Bi, Weichuan
Conference paper 7
Anti-obesity effect of tectorigenin isolated from rhizoma belamcandae: regulation on apolipoprotein A-IV promoter in Caco2/TC7 enterocytes
The 3rd International Symposium on Functional Foods 2008 - Health Benefits of Plant Polyphenols, organized by PolyU, Hong Kong, 5 April 2008
Guo, Ava Jiangyang; Choi, Chi Yan; Li, Jun; Duan, Ran; Li, Winnie Z.M.; Cheung, J.K.H.; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung
Development of new Chinese herbal decoction for anti-obesity
2008 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2008
Guo, Jiangyang; Huang, Wen; Duan, Ran; Li, Jun; Choi, Chi Yan; Dong, Tingxia; Lau, Brad W.C.; Tsim, Karl Wah Keung
Localization of Proline-Rich Membrane Anchor (PRiMA)-associated acetylcholinesterase in vertebrate neuromuscular junctions
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, August 16-20, 2008, P17
Leung, Ka Wing; Xie, Qunhui; Bi, Wenchuan; Cheung, Ka Hei; Mok, Ka Wai; Choi, Chi Yan; Tsim, Karl Wah Keung
Osteogenic effect of PRiMA-linked acetylcholinesterase in cultured MG-63 osteocarcoma cells
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, 16-20, August, 2008
Choi, Chi Yan; Zhu, Tingting; Xie, Qunhui; Chu, Kin Yan; Lau, Faye; Chen, Ping; Lin, Huangquan; Wan, David C.C.; Tsim, Karl Wah Keung
Regulation of PRiMA-linked acetylcholinesterase in muscles, neurons and osteoblasts
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, 16-20 August, 2008
Tsim, Karl Wah Keung; Xie, Qunhui; Leung, Ka Wing; Zhu, Tingting; Chu, Kin Yan; Chen, Ping; Guo, Jiangyang; Choi, Chi Yan
Studies on Dangui Buxue Tang: and example of Chinese herbal decoction flavonoids originated from Chinese Materia Medica (CMM): protect neurons against oxidative stress and beta-amyloid-induced cytotoxicity
2008 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six local universities, Hong Kong, 15 August 2008
Zhu, Tingting; Choi, Chi Yan; Cheung, Wing Han; Gao, Qiutao; Li, Jun; Dong, Tingxia; Tsim, Karl Wah Keung
Synergistic action of baicalein and daidzein in estrogenic and neuroprotective effects: development of potential health products and therapeutic drugs against alzheimer's disease
The 3rd International Symposium on Functional Foods 2008 - Health Benefits of Plant Polyphenols, organized by PolyU, Hong Kong, 5 April 2008
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Li, Jun; Li, Winnie Z.M.; Duan, Ran; Dong, Ting Xia; Tsim, Karl Wah Keung
Article 16
Calcitonin gene-related peptide induces the expression of acetylcholinesterase-associated collagen ColQ in muscle: a distinction in driving two different promoters between fast- and slow-twitch muscle fibers
Journal of neurochemistry, v. 102, (4), 2007, AUG, p. 1316-1328
Choi, Roy Chi Yan; Ting, Annie K.L.; Lau, Faye T.C.; Xie, Heidi Quihui; Leung, Ka Wing; Chen, Vicky Ping; Siow, Nina Lam; Tsim, Karl Wah Keung
Cloning and characterization of the yjeA gene, encoding a novel deoxyribonuclease, from Bacillus subtilis
Journal of Biochemistry, v. 142, (5), 2007, Nov, p. 647-654
Ng, Ka Lun; Lam, Chui Chi; Fu, Zhibiao; Han, Yi-Fan; Tsim, Karl Wah Keung; Wong, Wan Keung
Danggui Buxue Tang - A Chinese herbal decoction activates the phosphorylations of extracellular signal-regulated kinase and estrogen receptor alpha in cultured MCF-7 cells
FEBS letters, v. 581, (2), 2007, JAN 23, p. 233-240
Gao, Qiu T.; Choi, Roy Chi Yan; Cheung, Anna Wing Han; Zhu, Judy Ting Ting; Li, Jun; Chu, Glanice K.Y.; Duan, Ran; Cheung, Jerry K.H.; Jiang, Zhi Y.; Dong, Xiao B.; Zhao, Kui J.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Dang-Gui Buxue Tang protects against oxidant injury by enhancing cellular glutathione in H9c2 cells: Role of glutathione synthesis and regeneration
Planta medica, v. 73, (2), 2007, FEB, p. 134-141
Chiu, Po Yee; Leung, Hoi Yan; Siu, Ada H.Y.; Poon, Michel K.T.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Ko, Kam Ming
Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: A comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death
Journal of agricultural and food chemistry, v. 55, (6), 2007, MAR 21, p. 2438-2445
Zhu, Judy Ting Ting; Choi, Roy Chi Yan; Chu, Glanice K.Y.; Cheung, Wing Han; Gao, Qiu T.; Li, Jun; Jiang, Zhi Y.; Dong, Ting Xia; Tsim, Karl Wah Keung
HPLC法测定远志中总皂苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2007, (09), 2007, p. 1329-1332
李军; 董晓兵; 姜勇; 董婷霞; 屠鹏飞; 詹华强
Identification and quality control of Radix et Rhizoma Gentianae by chemical fingerprint: evaluation of gentiopicrin from different cultivated regions in China
Asian Journal of the Traditional Medicines, v. 1, (3-4), p. 1-9
Gao, Q.T.; Chou, G.X.; Dong, Tina Tingxia; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Tsim, Karl Wah Keung
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons
Journal of proteome research, v. 6, (7), 2007, p. 2435-2446
Fu, Hongjun; Li, Wenming; Liu, Yulin; Lao, Yuanzhi; Liu, Wei; Chen, Cheng; Yu, Hua; Lee, Nelson T.K.; Chang, Donald C.; Li, Peng; Pang, Yuanping; Tsim, Karl Wah Keung; Li, Mingtao; Han, Yifan
Regions in China identification and quality control of radix Codonopsis by chemical fingerprint: Evaluation of lobetyolin from different cultivated
Oriental Pharmacy and Experimental Medicine, v. 6, (4), 2006, p. 293-299
Chou, Gui X.; Gao, Qiu T.; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Chu, Glanice K.Y.; Jiang, Zhi Y.; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Regulation of a transcript encoding the proline-rich membrane anchor of globular muscle acetylcholinesterase - The suppressive roles of myogenesis and innervating nerves
Journal of biological chemistry, v. 282, (16), 2007, APR 20, p. 11765-11775
Xie, Heidi Qunhui; Choi, Roy Chi Yan; Leung, Ka Wing; Siow, Nina Lam; Kong, Ling W.; Lau, Faye T.C.; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung
Regulation of acetylcholinesterase expression by calcium signaling during calcium ionophore A23187-and thapsigargin-induced apoptosis
International journal of biochemistry & cell biology, v. 39, (1), 2007, p. 93-108
Zhu, Hui; Gao, Wei; Jiang, Hua; Jin, Qi-Huang; Shi, Yu-Fang; Tsim, Karl Wah Keung; Zhang, Xue-Jun
Simultaneous determination of phenols in Radix Polygalae by high performance liquid chromatography: Quality assurance of herbs from different regions and seasons
Journal of separation science, v. 30, (16), 2007, NOV, p. 2583-2589
Li, Jun; Dong, Xiaobing; Jiang, Yong; Gao, Qiutao; Jiang, Zhiyong; Cheung, Anna Wing Han; Duan, Ran; Dong, Tina Tingxia; Tu, Pengfei; Tsim, Karl Wah Keung
Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase
Molecular pharmacology, v. 71, (5), 2007, May, p. 1258-1267
Li, Wenming; Xue, Jian; Niu, Chunying; Fu, Hongjun; Lam, Colin S.C.; Luo, Jialie; Chan, Hugh H.N.; Xue, Huaiguo; Kan, Kelvin K.W.; Lee, Nelson Tsz Kin; Li, Chaoying; Pang, Yuanping; Li, Mingtao; Tsim, Karl Wah Keung; Jiang, Hualiang; Chen, Kaixian; Li, Xiaoyuan; Han, Yifan
Verification of the formulation and efficacy of Danggui Buxue Tang (a decoction of Radix Astragali and Radix Angelicae Sinensis): An exemplifying systematic approach to revealing the complexity of Chinese herbal medicine formulae
Chinese Medicine, v. 2, 2007
Gao, Qiutao; Li, Jun; Cheung, J.K.H.; Duan, Jinao; Ding, Anwei; Cheung, Anna Wing Han; Zhao, Kuijun; Li, Winnie Zhouming; Dong, Tina Tingxia; Tsim, Karl Wah Keung
测定天王补心丸和归脾丸中细叶远志皂苷的含量
中国中药杂志=China Journal of Chinese Materia Medica, v. 2007, (16), 2007, p. 1647-1649
董晓兵; 李军; 姜勇; 董婷霞; 屠鹏飞; 詹华强
远志皂苷对照品细叶远志皂苷的制备
中药新药与临床药理=Traditional Chinese Drug Research and Clinical Plarmacology, v. 2007, (01), 2007, p. 53-54
董晓兵; 李军; 郑颖; 董婷霞; 詹华强
Conference paper 18
A Chinese herbal decoction stimulates the expression of apolipoprotein A-IV in cultured enterocytes Caco 2 – TC7 cells: a possible drug for anti-obesity
2007 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six local universities, Hong Kong, 16 August 2007
Guo, A.J.Y.; Cheung, J.K.H.; Li, J.; Duan, Ran; Choi, Chi Yan; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung
A Chinese Herbal decoction, Danggui Buxue Tang (DBT), stimulates the release of cytokines in cultured T-lymphocytes: A signal triggered by extracellular signal-regulated kinase
2007 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six loca universities, Hong Kong, 16 August 2007
Cheung, J.K.H.; Gao, Q.T.; Li, J.; Jiang, Z.Y.; Chu, G.K.Y.; Duan, Ran; Cheung, Wing Han; Zhao, K.J.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung
A chinese herbal decoction, danggui buxue tang, activates extracellular signal-regulated kinase in cultured T-lymphocytes
FEBS letters, v. 581, (26), 2007, OCT 30, p. 5087-5093
Gao, Qiu T.; Cheung, Jerry K.H.; Li, Jun; Jiang, Zhi Y.; Chu, Glanice K.Y.; Duan, Ran; Cheung, Anna Wing Han; Zhao, Kul J.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Anti-obesity effect of a Chinese herbal decoction: Regulation of apolipoprotein A-IV expression and triglyceride formation
2007 TWGHs Eddie Wang Symposium on Integrated Chinese & Western Medicine, organized by Tung Wah Group of Hospitals & Hospital Authority, Hong Kong, 2 November 2007
Guo, A.J.Y.; Cheung, J.K.H.; Li, J.; Duan, Ran; Choi, Chi Yan; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung
ATP induces acetylcholinesterase gene expression in cortical neurons: transduction and transcription control via P2Y1 receptors
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Siow, Nina Lam; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Barnard, E.A.; Tsim, Karl Wah Keung
Characterization of proline-rich membrane anchor (PRiMA)-associated acetylcholinesterase in cholinergic synapses
The IXth International Meeting on Cholinesterases, Suzhou, China
Leung, Ka Wing; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung
Cloning and characterization of acetylcholinesterase of green pufferfish tetraodon nigroviridis
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Lau, L.S.; Tung, E.; Lin, H.Q.; Tsim, Karl Wah Keung; Wan, D.C.
Flavonoids derived from traditional Chinese medicine (TCM) in regulating the transcription of Acetylcholinesterase in osteosarcoma MG63 cells
2007 Hong Kong - Macau postgraduate symposium on Chinese medicine, Hong Kong,16 August 2007
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Xie, Qunhui; Ho, C.L.T.; Tsim, Karl Wah Keung
Flavonoids derived from traditional chinese medicine (TCM) regulate the transcription of acetylcholinesterase in osteosarcoma MG63 cells
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Xie, Qunhui; Ho, C.L.T.; Tsim, Karl Wah Keung
Flavonoids possess neuroprotective effects by preventing beta-amyloid-induced cell death on cultured neurons
2007 TWGHs Eddie Wang Symposium on Integrated Chinese & Western Medicine, organized by Tung Wah Group of Hospitals & Hospital Authority, Hong Kong, 2 November 2007
Zhu, J.T.; Chu, G.K.Y.; Dong, Ting Xia; Choi, Chi Yan; Tsim, Karl Wah Keung
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Li, W.; Fu, H.; Liu, Y.L.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Y.
Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity
The IXth International Meeting on Cholinesterases, Suzhou, China
Fu, H.; Li, Wenming; Pi, R.B.; Luo, J.L.; Pang, Y.P.; Tsim, Karl Wah Keung; Han, Y.
Regulation of a transcript encoding the proline-rich membrane anchor of globular muscle acetylcholinesterase: The suppressive roles of myogenesis and innervating nerves
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Leung, Ka Wing; Massoulie, J.; Tsim, Karl Wah Keung
Regulation of different subunits of acetylcholinesterase expression during the nerve growth factor-induced neuronal differentiation in cultured PC12 cells
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Choi, Chi Yan; Mok, M.K.W.; Leung, Ka Wing; Siow, Lam; Tsim, Karl Wah Keung
Stimulation of collagen-like subunit (ColQ) of acetylcholinesterase by muscular activity in muscle
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Lau, F.T.C.; Chen, Ping; Yim, J.C.H.; Choi, Chi Yan; Tsim, Karl Wah Keung
The expression of P2Y2, P2Y4 and P2Y6 receptors in cultured cortical neurons: signaling leads to acetylcholinesterases expression
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Chu, G.K.Y.; Siow, Lam; Choi, Chi Yan; Tsim, Karl Wah Keung
The motor nerve directs the oligomerization of collagen-tailed form acetylcholinesterase in muscles
The IXth International Meeting on Cholinesterases, Suzhou, China
Chen, Ping; Xie, Qunhui; Lau, F.T.C.; Choi, Chi Yan; Tsim, Karl Wah Keung
Transcriptional control of different subunits of AChE in muscle: a regulation mediated by CAMP-dependent signaling cascades
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Tsim, Karl Wah Keung
Article 18
A Chinese herbal decoction, Danggui Buxue Tang, prepared from Radix Astragali and Radix Angelicae Sinensis stimulates the immune responses
Planta Medica, v. 72, (13), 2006, Oct, p.1227-1231
Gao, Qiutao; Cheung, J.K.H.; Li, Jun; Chu, Glanice K.Y.; Duan, Ran; Cheung, Anna Wing Han; Zhao, Kuijun; Dong, T.T.X.; Tsim, Karl Wah Keung
A fructan, from radix ophiopogonis, stimulates the proliferation of cultured lymphocytes: Structural and functional analyses
Journal of natural products, v. 69, (9), 2006, SEP 22, p. 1257-1260
Wu, Xiangmei; Dai, Hui; Huang, Lixin; Gao, Xiaoming; Tsim, Karl Wah Keung; Tu, Pengfei
Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels
Journal of neurochemistry, v. 98, (5), 2006, SEP, p. 1400-1410
Fu, Hongjun; Li, Wenming; Lao, Yuanzhi; Luo, Jialie; Lee, Nelson T.K.; Kan, Kelvin K.W.; Tsang, Hing Wai; Tsim, Karl Wah Keung; Pang, Yuanping; Li, Zhiwang; Chang, Donald C.; Li, Mingtao; Han, Yifan
Chemical and biological assessment of a chinese herbal decoction containing radix astragali and radix angelicae sinensis: Determination of drug ratio in having optimized properties
Journal of agricultural and food chemistry, v. 54, (7), 2006, APR 5, p. 2767-2774
Dong, Tina Tingxia; Zhao, Kuijun; Gao, Qiutao; Ji, Zhaoning; Zhu, Ting T.; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Tsim, Karl Wah Keung
Chick acetylcholinesterase promoter regulation
Journal of molecular neuroscience, v. 30, (1-2), 2006, p. 33-34
Wan, David Chi Cheong; Zhang, Xiang; Siow, Nina L.; Xie, Heidi Qun Hui; Tsim, Karl Wah Keung
Dang-Gui Buxue Tang produces a more potent cardioprotective effect than its component herb extracts and enhances glutathione status in rat heart mitochondria and erythrocytes
Phytotherapy research, v. 20, (7), 2006, JUL, p. 561-567
Mak, Duncan Hon Fai; Chiu, Po Yee; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Ko, Kam Ming
Ginsenoside Re attenuate beta-amyloid and serum-free induced neurotoxicity in PC12 cells
Journal of ethnopharmacology, v. 107, (1), 2006, AUG 11, p. 48-52
Ji, Z.N.; Dong, Tina Ting Xia; Ye, W.C.; Choi, Roy Chi Yan; Lo, Chun Kit; Tsim, Karl Wah Keung
HPLC-ELSD Determination of Platycodin E in Radix Platcodonis of Different Sources
Chinese Journal of Pharmaceutical Analysis, 2006
Xia, Q.; Dong, Ting Xia; Tsim, Karl Wah Keung; Huang, Z.; Zhang, P.
HPLCELSD法测定不同来源桔梗中桔梗皂苷E的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2006, (05), 2006, p. 637-639
夏泉; 董婷霞; 詹华强; 黄赵刚; 张平
Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia
Phytomedicine, v. 13, (6), 2006, Jun, p. 428-433
Li, Shaoping; Zhang, Guihong; Zeng, Qingshu; Huang, Zhaogang; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung
ICP-MS法测定4种中药材中重金属含量
高等学校化学学报=China Journal of Chinese Materia Medica, v. 2007, (16）, 2007, p. 1314-1317
温慧敏; 陈晓辉; 董婷霞; 詹华强; 毕开顺
In vitro estrogenic activity of formononetin by two bioassay systems
Gynecological endocrinology, v. 22, (10), 2006, OCT, p. 578-584
Ji, Zhao-Ning; Zhao, W.Y.; Liao, G.R.; Choi, Roy Chi Yan; Lo, Chun Keung; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine
NeuroReport, v. 17, (5), 2006, April, p. 471-474
Li, Wenming; Lee, Nelson Tsz Kin; Fu, Hongjun; Kan, Kelvin K.W.; Pang, Yuanping; Li, Mingtao; Tsim, Karl Wah Keung; Li, Xiaoyuan; Han, Yifan
Quality control of Cordyceps sinensis, a valued traditional Chinese medicine
Journal of pharmaceutical and biomedical analysis, v. 41, (5), 2006, Aug, p. 1571-1584
Li, Shaoping; Yang, Fengqing; Tsim, Karl Wah Keung
Simultaneous determination of 11 saponins in Panax notoginseng using HPLC-ELSD and pressurized liquid extraction
Journal of separation science, v. 29, (14), 2006, SEP, p. 2190-2196
Wan, Jian-Bo; Li, Peng; Li, Shaoping; Wang, Yitao; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung
Transcriptional control of different acetylcholinesterase subunits in formation and maintenance of vertebrate neuromuscular junctions
Journal of molecular neuroscience, v. 30, (1-2), 2006, p. 189-192
Tsim, Karl Wah Keung; Xie, Heidi Qun Hui; Ting, Annie; Siow, Nina L.; Ling, Karen K.Y.; Kong, Lingwei
固相萃取-毛细管气相色谱法测定党参、龙胆中15种有机氯农药的残留量
沈阳药科大学学报=Journal of Shenyang Pharmaceutical University, v. 2006, (12), 2006, p. 776-781
张潇潇; 陈晓辉; 董婷霞; 詹华强; 王晓东; 毕开顺
莪术二酮对ADP诱导的兔血小板聚集的抑制作用
中国药理学通报=Chinese Pharmacological Bulletin, v. 2006, (09), 2006, p. 1151-1152
夏泉; 董婷霞; 詹华强; 梁嘉荣; 李绍平
Book 1
从西方思维看中药现代化
从西方思维看中药现代化 = Modernization of traditional Chinese medicine: a prospect from Western medicine / 孔宪铎, 詹华强着. 香港: 三联书店(香港)有限公司, 2006
Kung, Shain-Dow; Tsim, Karl Wah Keung
Book chapter 1
Quality Control of Cordyceps Sinensis, a Valued Traditional Chinese Medicine
/ Edited by J.N. Govil, V.K. Singh. Houston, Tex.: Studium Press LLC
Li, S.P.; Tsim, Karl Wah Keung
Conference paper 28
A Chinese herbal decoction, Danggui Buxue Tang, prepared from Radix Astragali and Radix Angelicae Sinensis stimulates the immune responses
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Gao, Q.T.; Cheung, J.K.H.; Cheung, Wing Han; Dong, Ting Xia; Tsim, Karl Wah Keung
Activation of P2Y1 receptor induces NR2A expression in cultured cortical neurons
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December , 2006
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung
ATP Induces Post-Synaptic Specializations in Synapses: Transduction and Transcription control
Croucher Advanced Study Institution (ASI): Signaling in Cell Growth and Deifferentitaion, 16-20 Jan, 2006
Tsim, Karl Wah Keung
Cordysinocan, a novel polysaccharide isolated from Cordyceps sinensis, stimulates the immune responses
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Cheung, J.K.H.; Cheung, Wing Han; Dong, Ting Xia; Tsim, Karl Wah Keung
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 Nanjing International Forum on Traditional Chinese Medicine, organized by Nanjing university of traditional chinese medicine and Administration of TCM of Jiangsu province, Nanjing, 4-6 November, 2006
Tsim, Karl Wah Keung
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Tsim, Karl Wah Keung
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 Shanghai Forum on International Standardization of Chinese Medicines and Herbal Products, organized by Shanghai University of Traditional Chinese Medicine and Shanghai R&D Center for Standardization of Chinese Medicine, Shanghai, 10 December, 2006
Tsim, Karl Wah Keung
Determination of Tectoridin as Irisflorentin in Rhizoma Belamcandae
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Li, J.; Dong, X.B.; Gao, Q.T.; Dong, Ting Xia; Tsim, Karl Wah Keung
Fractionation of Anti-platelet Aggregation Activity From Roots of Panax notoginsen
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Jiang, Z.Y.; Li, S.P.; Duan, Ran; Chen, J.J.; Dong, Ting Xia; Tsim, Karl Wah Keung
Identification and characterization of flavonoids from traditional Chinese medicines-drug discovery for neruoprotection
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Zhu, J.T.T.; Chu, G.K.Y.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung
Identification and characterization of flavonoids from traditional Chinese medicines-Drug discovery for neuroprotection
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Zhu, Judy T T; Chu, G.K.Y.; Cheung, Wing Han; Choi, Chi Yan; Dong, Ting Xia; Li, J.; Gao, Q.T.; Jiang, Z.Y.; Tsim, Karl Wah Keung
Identification and characterization of interacting partners of PRiMA, a membrane anchor of acetylcholinesterase-A proteomic approach
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Leung, Ka Wing; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung
Immuno-stimulating study on polysaccharide isolated from cultured Cordyceps
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Cheung, J.K.H.; Li, S.P.; Li, J.; Tsim, Karl Wah Keung
Isolation of active compound responsible for the anti-platelet aggregation from Radix Notoginseng
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Jiang, Z.Y.; Duan, Ran; Chen, J.J.; Leung, D.H.F.; Dong, Ting Xia; Tsim, Karl Wah Keung
Probing the effects of Chinese Medicine Materials (CMM) in stimulating the apolipoprotein A-IV (Apo A-IV) expression in cultured enterocytes Caco-2 / TC7 cells
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Duan, R.R.; Chan, E.Y.Y.; Li, J.; Raymond, M.P.; Lau, B.W.C.; Dong, Ting Xia; Tsim, Karl Wah Keung
Quantitative Proteomic Analysis of the Neuroprotection of Bis(7)-Tacrine Against Glutamate-Induced Mitochondrial Dysfunction
36th Annual Meeting of the Society for Neuroscience, Georgia World Congress Center, Atlanta, Georgia (USA), 14-18 Oct 2006
Fu, H.; Li, W.; Liu, Y.; Lao, Y.; Lee, N.T.; Liu, W.; Li, K.C.; Pang, Y.; Chang, Donald C; Tsim, Karl Wah Keung; Li, M.; Han, Y.
Radix Polygala protects PC12 cells from amyloid-beta peptide-induced neurotoxicity
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Li, J.; Chu, G.K.Y.; Dong, X.B.; Choi, Chi Yan; Lau, B.W.C.; Wong, Z.C.F.; Dong, Ting Xia; Tsim, Karl Wah Keung
Radix Polygala Protects PC12 Cells from Amyloid-Peptide-Induced Neurotoxicity
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Li, J.; Chu, G.K.Y.; Dong, X.B.; Choi, Chi Yan; Lau, B.W.C.; Dong, Ting Xia; Tsim, Karl Wah Keung
Regulation of acetylcholinesterase in neuron: The role of PRiMA in directing the formation of G4 AChE
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Choi, Chi Yan; Siow, Lam; Xie, Qunhui; Tsim, Karl Wah Keung
Regulation of Collagen-like subunit (ColQ) of acetylcholinesterase by muscular activity in muscles
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Lau, F.T.C.; Chen, Ping; Choi, Chi Yan; Tsim, Karl Wah Keung
Regulation of Transcript Encoding Proline-rich Membrane Anchor (PRiMA) of Globular form Acetylcholinesterase in Muscle: Suppressive Role of Myogenesis and Innervating Nerve
The 4th Congress of Federation of Asian and Oceanian Neuroscience Societies (FAONS), Hong Kong. 30 November - 2 December, 2006
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Leung, Ka Wing; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung
Specific estrogenic and immune regulatory effects of Danggui Buxue Tang-a traditional Chinaese herbal decoction prepared from Radix Angelicae Sinensis and Radix Astragali
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Gao, Q.T.; Cheung, J.K.H.; Cheung, Wing Han; Jiang, Z.Y.; Li, J.; Dong, Ting Xia; Tsim, Karl Wah Keung
Synergistic Neuroprotection by BIS(7)-Tacrine Via Moderate Blockade of N-Methyl-D-Aspartate Receptors and Selective Inhibition of Neuronal Nitric Oxide Synthase
36th Annual Meeting of the Society for Neuroscience, Georgia World Congress Center, Atlanta, Georgia (USA), 14-18 Oct 2006
Li, W.; Xue, J.; Niu, C.; Fu, H.; Lam, C.S.; Lee, N.T.; Pang, Y.; Li, M.; Jiang, H.; Chen, K.; Tsim, Karl Wah Keung; Li, X.; Han, Y.
The Effects of Zhikang Granules in stimulating the Apolipoprotein A-IV (Apo A-IV) Expression in Cultured Enterocytes Caco-2 / TC7 cells
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Dong, Ting Xia; Duan, Ran; Chan, E.Y.Y.; Li, J.; Tsim, Karl Wah Keung
The expression and functional role of P2Y2, P2Y4 and P2Y6 receptors in cultured cortical neurons
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Chu, G.K.Y.; Siow, Lam; Choi, Chi Yan; Tsim, Karl Wah Keung
The motor nerve directs the oligomerization of collagen-tailed form acetylcholinesterase in muscles
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Chen, Ping; Xie, Qunhui; Lau, F.T.C.; Choi, Chi Yan; Tsim, Karl Wah Keung
The Preparation of Tenuifolin as Chemical Market of Radix Polygalae
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Dong, X.B.; Li, J.; Dong, Ting Xia; Tsim, Karl Wah Keung
Traditional Chinese medicines reduce triglyceride accumulation in cultured adipocyte (3T3-L1 cells)
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Guo, A.J.Y.; Chu, G.K.Y.; Ho, C.L.T.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung
Article 17
A DNA microarray for the authentication of toxic traditional Chinese medicinal plants
Planta Medica, v. 71, (6), June 2005, p. 580-584
Carles, Maria C.; Cheung, Kin Lok; Moganti, Shanti; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu; Sucher, Nikolaus J.
An arabinogalactan isolated from the stems of Cistanche deserticola induces the proliferation of cultured lymphocytes
International journal of biological macromolecules, v. 37, (5), 2005, Dec, p. 278-282
Wu, Xiangmei; Gao, Xiaoming; Tsim, Karl Wah Keung; Tu, Pengfei
ATP induces the post-synaptic gene expression in neuron-neuron synapses: Transcriptional regulation of AChE catalytic subunit
Chemico-biological interactions, December 15, 2005, 157-158:423-426
Siow, Nina L.; Xie, Heidi Q.; Choi, Roy C.Y.; Tsim, Karl Wah Keung
ATP potentiates the formation of AChR aggregate in the co-culture of NG108-15 cells with C2C12 myotubes
FEBS letters, v. 579, (11), 2005, APR 25, p. 2469-2474
Ling, KKY; Siow, Nina Lam; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
Authentication and quality control of Cordyceps sinensis, a traditional Chinese medicine known as summer-grass winter-worm
Oriental Pharmacy and Experimental Medicine, v.5, (4), p.262-271
Cheung, Jerry K.H.; Li, Shaoping; Tsim, Karl Wah Keung
Danggui Buxue Tang (Chinese Angelica Decoction): A Sample Trial in TCM Standardization
Asia-Pacific Biotech News (APBN), v. 8, (23), 2004, Dec, p. 1316-1321
Tsim, Karl Wah Keung
Identificaiton of Stellaria medica by PCR
Journal of Chinese Pharmaceutical Sciences, v. 14, (3), 2005, p. 144-148
Huang, Wenzhe; Dong, Tina Tingxia; Qi, Huanyang; Lu, Zhenqiang; Tsim, Karl Wah Keung
Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry
Journal of pharmaceutical and biomedical analysis, v. 39, (3-4), 2005, SEP 15, p. 552-558
Yang, Fengqing; Li, Shaoping; Chen, Ying; Lao, Sincheng; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Molecular Genetic and Chemical Assessment of Rhizoma Curcumae in China
Journal of agricultural and food chemistry, v. 53, (15), 2005, Jul, p. 6019-6026
Xia, Quan; Zhao, Kuijun; Huang, Zhaogang; Zhang, Ping; Dong, Ting Xia; Li, Shaoping; Tsim, Karl Wah Keung
Novel dimeric acetylcholinesterase inhibitor bis(7)-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors
Journal of biological chemistry, v. 280, (18), 2005, MAY 6, p. 18179-18188
Li, Wenming; Pi, Rongbiao; Chan, Hugh H.N.; Fu, Hongjun; Lee, Nelson; Tsang, HingWai; Pu, Yongmei; Chang, Donald; Li, Chaoying; Luo, Jialie; Xiong, Keming; Li, Zhiwang; Xue, Hong; Carlier, Paul R.; Pang, Yuan-Ping; Tsim, Karl Wah Keung; Li, Mingtao; Han, Yifan
Orthogonal array design in optimizing the extraction efficiency of active constituents from roots of Panax notoginseng
Phytotherapy research, v. 19, (8), 2005, Aug, p. 684-688
Dong, Tina Tingxia; Zhao, Kuijun; Huang, W.Z.; Leung, Kawing; Tsim, Karl Wah Keung
Quantitative detection of gentiopicrin in Radix Gentianae
Shanghai Journal of Traditional Chinese medicine, v. 39, p.53-55
Chou, G.X.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wang, Z.T.; Yu, Z.L.
Regulation of PRiMA: membrane anchor of acetylcholinesterase (AChE) in neuron and muscle
Chemico-biological interactions, 2005, Dec, p. 157-158
Xie, Heidi Q.; Siow, Nina L.; Peng, H. Benjamin; Massoulié, Jean; Tsim, Karl Wah Keung
Species identification of Dyers woad leaf by DNA sequences of 5S-rRNA spacer domain and random amplified polymorphic DNA (RAPD)
Oriental Pharmacy and Experimental Medicine, v. 5, (2), p. 117-123
Zhao, K.J.; Dong, Tina Tingxia; Wong, Y.C.; Tu, P.F.; Tsim, Karl Wah Keung
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ in fast- and slow-twitch muscle fibers
Chemico-biological interactions, v. 157, (Sp. Iss. SI), 2005, DEC 15, p. 63-70
Ting, Annie; Siow, Nina L.; Kong, Lingwei; Tsim, Karl Wah Keung
三七中三七素的含量测定
中国药学杂志=Chinese Pharmaceutical Journal, v. 2005, 13, 2005, p. 1017-1019
崔秀明; 徐珞珊; 王强; 陈中坚; 董婷霞; 詹华强
不同来源莪术中莪术醇、吉马酮、莪术二酮GC-MS定量分析
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2005, (07), 2005, p. 827-830
杨丰庆; 李绍平; 陈莹; 刘倩青; 王一涛; 董婷霞; 詹华强
Conference paper 20
(43) ATP induces the post-synaptic gene expression in neuron-neuron synapses: Transcriptional regulation of AChE catalytic subunit
Chemico-Biological Interactions, v. 157, 2005, p. 423-426
Siow, Nina Lam; Xie, Heidi Qunhui; Choi, Roy Chi Yan; Tsim, Karl Wah Keung
(48) Regulation of PRiMA: Membrane anchor of acetylcholinesterase (AChE) in neuron and muscle
Chemico-Biological Interactions, v. 157, 2005, p. 432
Xie, Qunhui; Siow, Lam; Peng, Benjamin H; Massoulié, J.; Tsim, Karl Wah Keung
A cAMP-dependent Signaling Directs the Post-Synaptic Expression of ColQ, a Subunit of Collagen-Tailed form AChE, at the Vertebrate Neuromuscular Junctions.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Ting, A.K.L.; Massoulie, J.; Tsim, Karl Wah Keung
A Flavonol Glycoside, Isolated from Roots of Panax Notoginseng, Protects the Beta-Amyloid-Induced Neurotoxicity in Cultured PC12 Cells
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Zhu, Judy T T; Leung, Ka Wing; Cheung, J.K.H.; Zhao, K.J.; Dong, Ting Xia; Tsim, Karl Wah Keung
ATP induces post-synaptic gene expression in neuron-neuron synapses: the transcription regulation of NR2A subunit.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung
Calcitonin gene-related peptide mediates synaptic expression of collagen-like subunit (COLQ) of acetylcholinesterase in muscle
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Ting, A.K.L.; Choi, Chi Yan; Lau, F.T.C.; Massoulie, J.; Tsim, Karl Wah Keung
Characterization of chick AChE promoter: responses to nerve-derived factors
The 12th International Symposium on Cholinergic Mechanisms in Alicante, Spain, October 1-5, 2005
Wan, D.C.C.; Zhang, X.; Siow, Lam; Xie, H.Q.H.; Tsim, Karl Wah Keung
Functional roles of P2Y1 receptor in cultured cortical neurons: regulation of AChE expression and small GTPase activation
Neuroscience 2005 in Washington, D.C., 12-16 Nov 2005
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung
Identification of Critical Early Genes Involved in Nerve Growth Factor-Induced PC12 Differentiation
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5 - 6 December 2005
Xiao, Fang; Ng, Yu Pong; Tsim, Karl Wah Keung; Wise, Helen; Wong, Yung Hou; Ip, Nancy Yuk-Yu; Wu, Zhenguo
NGF-Induced Neuronal Differentiation of PC12 Cells: Delineation of Signaling Molecules and Mapping of Pathways.
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5 - 6 December 2005
Leung, W.K.W.; Choi, Chi Yan; Ip, Nancy Yuk-Yu; Wu, Zhenguo; Wong, Yung Hou; Cheung, P.T.; Tsim, Karl Wah Keung
Novel Dimeric Acetylcholinesterase Inhibitor Bis ( 7 ) - Tacrine Exerts Multiple Neuroprotective Activities by Inhibiting Nitric Oxide Synthase
35th Annual Meeting of the Society for Neuroscience, Washington Convention Center, Washington, DC (USA), 12-16 Nov 2005
Li, W.; Chan, H.H.N.; Xue, J.; Xue, Hong; Kan, K.K.W.; Zhao, Y.; Lee, N.T.K.; Luo, J.; Li, Z.; Carlier, P.R.; Pang, Y.; Tsim, Karl Wah Keung; Li, M.; Li, X.; Han, Yilong
Regulation of collagen-like subunit (COLQ) of acetylcholinesterase by muscular activity in muscle
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Lau, F.T.C.; Ting, A.K.L.; Massoulie, J.; Tsim, Karl Wah Keung
Regulation of NR2A, a subunit of N-methyl-d-aspartate receptor, by a cAMP-dependent signaling pathway in neuronal cultures
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Siow, Lam; Choi, Chi Yan; Xie, Qunhui; Tsim, Karl Wah Keung
Regulation of P2Y1 Receptor: Signal Transduction, Dimerization, Desensitization and Internalization
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Choi, Chi Yan; Wong, Cecilia S.S.; Barnard, E.A.; Tsim, Karl Wah Keung
Restricted Localization of P2Y1 Receptor in Cortical Neurons: Functional Role in Small GTPase Activation.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Ling, K.Y.; Kong, L.W.; Tsim, Karl Wah Keung
Role of Calmodulin-Dependent Kinase II in Nerve Growth Factor-Induced Differentiation of PC12 Cells.
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5-6 December 2005
Kam, Yuet Fong; Yung, Ying; Wu, Eddy H.T.; Ng, Yu Pong; Wu, Zhenguo; Tsim, Karl Wah Keung; Wise, Helen; Ip, Nancy Yuk-Yu; Wong, Yung Hou
Role of PRiMA in Regulating Globular Form of Acetylcholinesterase: The Possible Role of Ache Oligomeriztion
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung
The expression and localization of PRiMA, a membrane anchor of acetylcholinesterase, during neuron and muscle differentiation
Neuroscience 2005 in Washington, D.C., 12-16 Nov 2005
Xie, Qunhui; Siow, Lam; Ting, A.K.L.; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung
Transcriptional control of different subunits of acetylcholinesterase in the formation and maintenance of vertebrate neuromuscular junctions
The 12th International Symposium on Cholinergic Mechanisms in Alicante, Spain, October 1-5, 2005
Tsim, Karl Wah Keung; Xie, Qunhui; Ting, A.K.L.; Siow, Lam; Lau, F.; Kong, L.
Transcriptional regulation of PRiMA, a membrane anchor of globular form AChE, in neuron and muscle differentiation.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Xie, Qunhui; Siow, Lam; Ting, A.K.L.; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung
Article 7
ATP potentiates agrin-induced AChR aggregation in cultured myotubes - Activation of RhoA in P2Y1 nucleotide receptor signaling at vertebrate neuromuscular junctions
Journal of biological chemistry, v. 279, (30), 2004, JUL 23, p. 31081-31088
Ling, KKY; Siow, Nina Lam; Choi, Roy Chi Yan; Ting, AKL; Kong, LW; Tsim, Karl Wah Keung
Chemical and biological assessment of a traditional Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis: Orthogonal array design to optimize the extraction of chemical constituents
Planta medica, v. 70, (12), 2004, DEC, p. 1222-1227
Song, Zong H.; Ji, Zhaoning; Lo, Chunkeung; Dong, Tina Tingxia; Zhao, Kuijun; Ll, O.T.W.; Haines, Christopher John; Kung, Shain D.; Tsim, Karl Wah Keung
Distinction of water-soluble constituents between natural and cultured Cordyceps by capillary electrophoresis
Phytomedicine, v. 11, (7-8), 2004, NOV, p. 684-690
Li, Shaoping; Song, Zong H.; Dong, Tina Tingxia; Ji, Zhaoning; Lo, Chunkeung; Zhu, Shangquan; Tsim, Karl Wah Keung
Identification and quantification of 13 components in Angelica sinensis (Danggui) by gas chromatography-mass spectrometry coupled with pressurized liquid extraction
Analytica Chimica Acta, v. 526, (2), 2004, Nov, p. 131-137
Lao, Sincheng; Li, Shaoping; Kan, Kelvin K.W.; Li, Peng; Wan, Jianbo; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung
P2Y(2) receptor activation regulates the expression of acetylcholinesterase and acetylcholine receptor genes at vertebrate neuromuscular junctions
Molecular pharmacology, v. 66, (4), 2004, OCT, p. 794-806
Tung, EKK; Choi, Roy Chi Yan; Siow, Nina Lam; Jiang, JXS; Ling, KKY; Simon, J.; Barnard, EA; Tsim, Karl Wah Keung
Simultaneous determination of ergosterol, nucleosides and their bases from natural and cultured Cordyceps by pressurised liquid extraction and high-performance liquid chromatography
Journal of chromatography A, v. 1036, (2), 2004, May, p. 239-243
Li, Shaoping; Li, Peng; Lai, C.M.; Gong, Yuanxiang; Kan, Kelvin K.W.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wang, Yitao
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ - Differential expression in fast and slow twitch muscle fibers is driven by distinct promoters
Journal of biological chemistry, v. 279, (26), 2004, Jun, p. 27098-27107
Lee, Henry H.C.; Choi, Roy Chi Yan; Ting, Annie; Siow, Nina Lam; Jiang, Joy; Massoulié, Jean M.; Tsim, Karl Wah Keung
Book 1
A formula of TCM: Danggui Buxe Tang
Takungpao, 19 February
Tsim, Karl Wah Keung
Book chapter 3
Modernization of Traditional Chinese Medicine: Problems in Safety and Quality Assurance
Vision of 2050: Agriculture in China / Edited by Tso et al. New York
Tsim, Karl Wah Keung; Kung, Shain-Dow
The Biological and Pharmacological Properties of Cordyceps Sinensis, a Traditional Chinese medicine, that has Broad Clinical Applications
In: Herbal Medicines: Molecular Basis of Biological Activity and Health; Packer et al ed. Marcel Dekker Inc. New York / p. 657-682
Li, S.P.; Tsim, Karl Wah Keung
The Role of P2Y1 Nucleotide Receptors in the Formation and Maintenance of the Skeletal Neuromuscular Junctions
Cholinergic Mechanisms / p. 105-110
Tsim, Karl Wah Keung; Choi, Chi Yan; Siow, Lam; Cheng, Anthony W.M.; Ling, Karen K Y; Tung, E.K.K.; Kong, L.W.; Barnard, E.A.
Conference paper 8
Activation of P2Y1 Receptor Induces the Expression of AChE via MAP Kinase Signalling Pathway in Cultured Cortical Neurons
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 84
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung
ATP Induces the Post-Synaptic Gene Expression in Neuron-Neuron Synapses: the Promoter Analysis of AChE Catalytic Subunit.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung
ATP-Activated Rho A GTPase Modulate Agrin-Induced AChR Aggregation
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 85
Ling, K.K.Y.; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung
PriMA, the Membrane Anchor of Acetylcholinesterase in the Brain: Characterization and Function
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 85
Xie, Qunhui; Genin, A.; Choi, Chi Yan; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung
Regulation of PRiMA, the Membrane Anchor of of Acetylcholiesterase, During Neuron and Muscle Differentiation.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Xie, Qunhui; Siow, Lam; Ting, A.K. L.,; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung
Transcription Regulation of Collagen-Tailed Subunit of Acetylcholinesterase in Muscle
6th APSN meeting in Hong Kong, J. Neurochem, v. 88, (suppl), p. 85
Ting, A.K.L.; Lee, H.H.C.; Choi, Chi Yan; Massoulie, J.; Tsim, Karl Wah Keung
Transcriptional Regulation of AChE-Associated Collagen ColQ: Differential Expression in Fast-and Slow-Twitch Muscle Fibers is Driven by Distinct Promoters.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Tsim, Karl Wah Keung
Two Distinct Promoters of AChE Gene in Chicken are Responsible for Tissue-Specific Expression of Different Transcripts
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 38
Tung, E.K.K.; Zhang, X.; Choi, Chi Yan; Tsim, Karl Wah Keung; Wan, D.C.C.
Article 13
A polysaccharide isolated from Cordyceps sinensis, a traditional Chinese medicine, protects PC12 cells against hydrogen peroxide-induced injury
Life sciences, v. 73, (19), 2003, SEP 26, p. 2503-2513
Li, Shaoping; Zhao, Kuijun; Ji, Zhaoning; Song, Zong H.; Dong, Tina Tingxia; Lo, Chunkeung; Cheung, J.K.H.; Zhu, Shangquan; Tsim, Karl Wah Keung
ATP acts via P2Y(1) receptors to stimulate acetylcholinesterase and acetylcholine receptor expression: Transduction and transcription control
JOURNAL OF NEUROSCIENCE, v. 23, (11), 2003, JUN 1, p. 4445-4456
Choi, Roy Chi Yan; Siow, Nina Lam; Cheng, Anthony WM; Ling, Karen KY; Tung, EKK; Simon, J.; Barnard, EA; Tsim, Karl Wah Keung
ATP induces post-synaptic gene expressions in vertebrate skeletal neuromuscular junctions
Journal of neurocytology, v. 32, (5-8), 2003, JUN-SEP, p. 603-617
Tsim, Karl Wah Keung; Choi, Roy Chi Yan; Siow, Nina Lam; Cheng, AWM; Ling, KKY; Jiang, JXS; Tung, EKK; Lee, HHC; Xie, Heidi Qunhui; Simon, J.; Barnard, EA
Authentication of Panax notoginseng by 5S-rRNA spacer domain and random amplified polymorphic DNA (RAPD) analysis
Planta medica, v. 69, (6), 2003, Jun, p. 584-586
Cui, Xiuming; Lo, Chunkeung; Yip, K.L.; Dong, Tina Tingxia; Tsim, Karl Wah Keung
CDNA encodes Xenopus P2Y(1) nucleotide receptor: expression at the neuromuscular junctions
NeuroReport, v. 14, (3), 2003, MAR 3, p. 351-357
Cheng, Anthony WM; Kong, LW; Tung, EKK; Siow, Nina Lam; Choi, Roy Chi Yan; Zhu, SQ; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung
Characterization of a rhamnogalacturonan and a xyloglucan from Nerium indicum and their activities on PC12 pheochromocytoma cells
Journal of natural products, v. 66, (1), 2003, Jan, p. 7-10
Ding, Kan; Fang, Jinian; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wu, Houming
Chemical assessment of roots of Panax notoginseng in China: Regional and seasonal variations in its active constituents
Journal of agricultural and food chemistry, v. 51, (16), 2003, Jul, p. 4617-4623
Dong, Tina Tingxia; Cui, Xiuming; Song, Zong H.; Zhao, Kuijun; Ji, Zhaoning; Lo, Chunkeung; Tsim, Karl Wah Keung
Genetic distinction of Radix Adenophorae from its adulterants by the DNA sequence of 5S-rRNA spacer domains
American Journal of Chinese Medicine, v. 31, (6), 2003, p. 919-926
Zhao, Kuijun; Dong, Tina Tingxia; Cui, Xiuming; Tu, Pengfei; Tsim, Karl Wah Keung
Molecular genetic and chemical assessment of radix angelica (Danggui) in China
Journal of agricultural and food chemistry, v. 51, (9), 2003, Apr, p. 2576-2583
Zhao, Kuijun; Dong, Tina Tingxia; Tu, Pengfei; Song, Zong H.; Lo, Chunkeung; Tsim, Karl Wah Keung
Muscle induces neuronal expression of acetylcholinesterase in neuron-muscle co-culture - Transcriptional regulation mediated by camp-dependent signaling
Journal of biological chemistry, v. 278, (46), 2003, NOV 14, p. 45435-45444
Jiang, JXS; Choi, Roy Chi Yan; Siow, Nina Lam; Lee, HHC; Wan, DCC; Tsim, Karl Wah Keung
Phylogeny of Astragalus in China: Molecular evidence from the DNA sequences of 5S rRNA spacer, ITS, and 18S rRNA
Journal of agricultural and food chemistry, v. 51, (23), 2003, Nov, p. 6709-6714
Dong, Tina Tingxia; Ma, Xiaoqiang; Clarke, Clarles; Song, Zong H.; Ji, Zhaoning; Lo, Chunkeung; Tsim, Karl Wah Keung
Signalling pathways and ion channel regulations of P2Y receptors
Drug development research, v. 59, (1), 2003, MAY, p. 36-48
Barnard, Eric A.; Simon, Joseph; Tsim, Karl Wah Keung; Filippov, Alexander K.; Brown, David A.
建立评价当归质量的HPLC指纹图谱分析方法
中国药学杂志=Chinese Pharmaceutical Journal, v. 2003, (10), 2003
刘荣霞; 周婷婷; 董婷霞; 詹华强; 毕开顺
Conference paper 4
Bis(7)-tacrine Attenuates Glutamate-Induced Apoptosis in Rat Cerebellar Granule Neurons by Regulating Calcium Homeostasis
Society for Neuroscience, 33rd Annual Meeting, New Orleans, LA, USA
Li, Wenming; Pi, Rongbiao; Chan, H.H.N.; Lee, N.T.K.; Tsang, H.W.; Pu, Y.M.; Wang, W.Y.; Chan, J.L.N.; Leung, W.C.; Xue, Hong; Chang, Donald C; Sucher, Nikolaus J.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Y.
Prevention of b-amyloid-induced Neurotoxicity in Cultured PC12 Cells by Ginsenoside and Favonoid Isolated from Roots of Panax Notoginseng
11th Euroconferecne on Aptoptosis in Ghent, Belgium
Wan, D.C.C.; Ji, Z.N.; Song, Z.H.; Lo, Chun Keung; Cheung, J.K.H.; Dong, Ting Xia; Tsim, Karl Wah Keung
PRiMA, the Membrane Anchor of Acetylcholinesterase in the Brain: Searching for its Proteic Partners Using the Yeast-two hybrid system
The 23rd Annual Scientifc Meeting, The Hong Kong Society of Neurosciences, Hong Kong, PP4, 9-10 December
Xie, Qunhui; Genin, Alexis; Choi, Chi Yan; Peng, Benjamin H; Massoulie, Jean; Tsim, Karl Wah Keung
Transcriptional Regulation of Collagen-Tailed Subunit (ColQ) of Acetylcholinesterase (AChE) in Muscle
The 23rd Annual Conference of The Hong Kong Society of Neurosciences
Ting, A.K.L.; Lee, H.H.C.; Massoulie, J.; Tsim, Karl Wah Keung
Article 12
A cyclic AMP-dependent pathway regulates the expression of acetylcholinesterase during myogenic differentiation of C2C12 cells
Journal of biological chemistry, v. 277, (39), 2002, SEP 27, p. 36129-36136
Siow, Nina Lam; Choi, Roy Chi Yan; Cheng, Anthony WM; Jiang, JXS; Wan, DCC; Zhu, SQ; Tsim, Karl Wah Keung
Chemical analysis of Radix Astragali (Huangqi) in China: A Comparison with its Adulterants and Seasonal Variations
Journal of agricultural and food chemistry, v. 50, (17), 2002, Aug, p. 4861-4866
Ma, Xia Q.; Shi, Q.; Duan, Jinao; Dong, Ting Xia; Tsim, Karl Wah Keung
Determination of flavonoids in Pana notoginseng
Chinese Traditional and Herbal Drugs, v. 33, (7), p. 611-612
Cui, Xiu M.; Dong, Tina Tingxia; Huang, Wen Z.; Chen, Zhong J.; Tsim, Karl Wah Keung
Identification on Panax notoginseng and its adulterants by HPLC fingerprint chromatogram
Chin. Trad. and Herb. Drugs, v. 33, (10), p. 941-943
Cui, Xiu M.; Dong, Tina Tingxia; Chen, Zhong J.; Tsim, Karl Wah Keung
The development of TCM formula and patent drugs
Traditional Chinese Drug Research and Clinical Pharmacology, v. 13, (6), p. 343-345
Su, Ziren; Huang, Xiao D.; Dong, Tina Tingxia; Tsim, Karl Wah Keung
The fruiting body and its caterpillar host of Cordyceps sinensis show close resemblance in main constituents and anti-oxidation activity
Phytomedicine, v. 9, (4), 2002, MAY, p. 319-324
Li, Shaoping; Su, Ziren; Dong, Tina Tingxia; Tsim, Karl Wah Keung
The heat-induced degradation of magnolol and honokiol in supercritical fluid CO2 extraction from Magnolia bark
Yaoxue Xuebao, v. 37, (11), 2002, Nov, p. 870-875
Su, Ziren; Dong, Tina Tingxia; Lo, Chunkeung; Tsim, Karl Wah Keung
The signaling pathways mediated by P2Y nucleotide receptors in the formation and maintenance of the skeletal neuromuscular junction
NeuroSignals, v. 11, (1), 2002, JAN-FEB, p. 58-64
Tsim, Karl Wah Keung; Barnard, Eric A.
三七中黄酮成分的含量测定
中草药=Chinese Traditional and Herbal Drugs, v. 2002, (07), 2002
崔秀明; 董婷霞; 黄文哲; 陈中坚; 詹华强
三七及其混淆品的HPLC指纹图谱鉴定
中草药=Chinese Traditional and Herbal Drugs, v. 2002, (10), 2002
崔秀明; 董婷霞; 陈中坚; 詹华强
三七多糖成分的含量测定及其变化
中国药学杂志=Chinese Pharmaceutical Journal, v. 2002, (11), 2002
崔秀明; 董婷霞; 陈中坚; 王朝梁; 詹华强
高温致厚朴SFE－CO2萃取物中厚朴酚、和厚朴酚降解
药学学报=Acta Pharmaceutica Sinica, v. 2002, (11), 2002, p. 870-875
苏子仁; 董婷霞; 卢振强; 詹华强
Conference paper 9
Apoptosis in Rat Cerebellar Granule Neurons
Society for Neuroscience, 32nd Annual Meeting, Orlando, Florida
Li, Wenming; Chan, Hiu Nam; Lee, Tsz Kin Nelson; Xie, Y.B.; Ho, Chi Ming; Carlier, P.R.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Yi Fan
ATP, Mediated by Rho A GTPase, Potentiates the Agrin-Induced AChR Aggregation in Cultured Chick Myotubes
22nd Annual Conference of The Hong Kong Society of Neurosciences
Ling, Karen K Y; Choi, Chi Yan; Tsim, Karl Wah Keung
Expression and Localization of Different P2Y Receptors in Cultured Cortical Neurons
22nd Annual Conference of The Hong Kong Society of Neurosciences
Siow, Lam; Choi, Chi Yan; Barnard, Eric A.; Tsim, Karl Wah Keung
Functional Roles of P2Y2 and P2Y4 Nucleotide Receptors in the Formation and Maintenance of the Neuromuscular Junctions
22nd Annual Conference of The Hong Kong Society of Neurosciences
Tung, Edmund K.K.; Choi, Chi Yan; Siow, Lam; Barnard, Eric A.; Tsim, Karl Wah Keung
Huperzine A, a Promising Anti-Alzheimer's Agent, Reduces Staurosporine-Induced Apoptosis in NG108-15 Cells
XIth International symposium on cholinergic mechanisms-function and dysfunction & 2nd misrahi symposium on neurobiology, 5-9 May, St. Moritz, Switzerland
Han, Yi Fan; Xiao, Xiao-Qiu; Wu, Dong-Cheng; Gao, Yang; Ho, Wing-Lok; Lee, Tze-Kin Nelson; Fu, Yan; Tsim, Karl Wah Keung
PriMA, the Membrane Anchor of AChE in the Brain: Searching for its Proteic Partners Using the Yeast-Two Hybrid System
22nd Annual Conference of The Hong Kong Society of Neurosciences
Xie, Qui H.; Genin, Alexis; Peng, Benjamin H; Massoulie, Jean; Tsim, Karl Wah Keung
Regulation of Neuronal AChE Expression by Muscle in Neuron-Muscle Co-Cultures
22nd Annual Conference of The Hong Kong Society of Neurosciences
Jiang, Joy X.S.; Tsim, Karl Wah Keung
The Transcriptional Regulation of Collagen-Tailed (ColQ), a Subunit of Asymmetric Acetylcholinesterase is Muscle Fibre-Type-Specific Dependent
22nd Annual Conference of The Hong Kong Society of Neurosciences
Lee, Henry H.C.; Genin, Alexis; Tsim, Karl Wah Keung
Two Alternative Promoters for Chicken Acetylcholinesterase Gene and Tissue-Specific Transcription
22nd Annual Conference of The Hong Kong Society of Neurosciences
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C.
Article 16
Advance of Anti-tumor for Cordyceps sinensis
Chinese Traditional & Herbal Drugs, v. 32, p. 373-375
Li, Shao Ping; Ji, Hui; Li, Ping; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Li, Wen Qi
Anti-oxidation activity of different types of natural Cordyceps sinensis and cultured Cordyceps mycelia
Phytomedicine, v. 8, (3), 2001, May, p. 207-212
Li, Shao Ping; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Authentic Identification of Stigma Croci (Stigma of Crocus sativus) from its Adulterants by Molecular Genetic Analysis
Planta medica, v. 67, (2), 2001, Mar, p. 183-186
Ma, Xia Q.; Zhu, Dayuan; Li, Shao Ping; Dong, Ting Xia; Tsim, Karl Wah Keung
Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction
Nature Neuroscience, v. 4, (4), April 2001, p. 374-381
Fu, Amy Kit Yu; Fu, Wing Yu; Cheung, Janet; Tsim, Karl Wah Keung; Ip, Fanny Chun Fun; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu
Chips and Qi: Microcomponent-Based Analysis in Traditional Chinese Medicine
Fresenius Journal of Analytical Chemistry, v. 371, (2), September 2001, p. 190-194
Carles, Maria; Lee, Ming Hung Thomas; Moganti, Shanti; Lenigk, Ralf; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu; Hsing, I-Ming; Sucher, Nikolaus J.
Comments on the change of drug nature and innovation of Chinese patent drugs in the preparing process
Traditional Chinese Drug Research and Clinical Pharmacology, v. 13, p. 1-4
Su, Ziren; Chen, Jiannan; Shen, Xiaoling; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Determination of nucleosides in natural Cordyceps sinensis and cultured Cordyceps mycelia by capillary electrophoresis
Electrophoresis, v. 22, (1), 2001, p. 144-150
Li, Shao Ping; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Determination of water-soluble constituents from the drug materials of 'Honghua'
Journal of Pharmaceutical Practice, v. 18, p. 310-311
Ma, Xiaoqing; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Expression of the P2Y1 nucleotide receptor in chick muscle: Its functional role in the regulation of acetylcholinesterase and acetylcholine receptor
Journal of Neuroscience, v. 21, (23), December 2001, p. 9224-9234
Choi, Roy Chi Yan; Man, Menlisa L.S.; Ling, Karen K.Y.; Ip, Nancy Yuk-Yu; Simon, Joseph; Barnard, Eric A.; Tsim, Karl Wah Keung
The contents and their change of nucleosides from natural Cordyceps sinensis and cultured Cordyceps mycelia
Yaoxue Xuebao, v. 36, (6), 2001, June, p. 436-439
Li, Shao Ping; Li, Ping; Ji, Hui; Zhang, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung
The Cyclic AMP-Mediated Expression of Acetylcholinesterase in Myotubes Shows Contrasting Activation and Repression between Avian and Mammalian Enzymes
Molecular and Cellular Neuroscience, v. 17, (4), April 2001, p. 732-745
Choi, Roy Chi Yan; Siow, Nina Lam; Zhu, Shangquan; Wan, David Chi Cheong; Wong, Yung Hou; Tsim, Karl Wah Keung
The Nucleosides Contents and Their Variation in Natural Cordyceps sinensis and Cultured Cordyceps Mycelia
Journal of Chinese Pharmaceutical Sciences=药学学报, v. 10 , (4), 2001, p. 175-179
Li, Shaoping; Li, Ping; Ji, Hui; Zhu, Quan; Dong, Tina T.X.; Tsim, Karl Wah Keung
The nucleotides contents and their variation in natural Cordyceps sinensis and cultured Cordyceps mycelia
Journal of Chinese Pharmaceutical Sciences, v. 10, (4), 2001, p. 175-179
Li, Shaoping; Li, Ping; Ji, Hui; Zhang, Ping; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
The separation and reconstitution of active ingredients of TCM
Chinese Traditional Patent Medicine, 23: 615-616
Su, Ziren; Dong, Tina Tingxia; Chan, Jian Nan; Tsim, Karl Wah Keung
冬虫夏草抗肿瘤作用研究进展
中草药, v. 32, (4), 2001, p. 373-375
李绍平; 季晖; 李萍; 董婷霞; 詹华强; 李文琪
毛细管电泳法测定冬虫夏草中核苷类的含量
药物分析杂志, v. 21, (2), 2001, p. 77-79
李绍平; 李萍; 季晖; 董婷霞; 詹华强
Book chapter 1
Analysis of Carbohydrates from Natural Cordyceps Sinensis and Cultured Cordyceps Mycelia by HPLC
Forum of Modern Pharmaceutical Analysis, Xinhua Press, Beijing / p. 149-151
Li, Shao Ping; Dong, Ting Xia; Su, Zi Ren; Zhu, Quan; Tsim, Karl Wah Keung
Conference paper 5
Cloning and Characterization of Acetylcholinesterase Gene in Chicken
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C.
Cloning of Chicken Acetylcholinesterase Gene and Characterization of its Putative Promoter Activity
The 21st Annual Conference of The Hong Kong Society of Neurosciences
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C.
NFkB Regulates the Activity of Human Acetylcholinesterase Promoter in Muscle
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Choi, Chi Yan; Siow, Lam; Cheng, Anthony W.M.; Zhang, Xiang; Wan, David C.C.; Tsim, Karl Wah Keung
Regulation of AChR and AChE by of P2Y1 Nucleotide Receptor During the Formation of Neuromuscular Junctions
Annual Meeting Society for Neurosciences (USA), 2001-2002
Tsim, Karl Wah Keung; Choi, Chi Yan; Ling, Karen; Kong, Ling Wei; Barnard, Eric
The Role of P2Y Nucleotide Receptors in the Formation of Neuromuscular Junctions
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Tsim, Karl Wah Keung; Barnard, Eric
Article 7
Authentication of an animal crude drug, Zaocys, by diagnostic PCR
Biological & pharmaceutical bulletin, v. 23, (5), 2000, May, p. 585-588
Wang, Yiquan; Zhou, Kaiya; Xu, Luoshan; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Chemical comparison of Astragali Radix (Huangqi) from Different Regions of China
Natural Medicines, v. 54, (5), 2000, p. 213-218
Ma, Xia Q.; Duan, Jinao; Zhu, Dayuan; Dong, Ting Xia; Tsim, Karl Wah Keung
Immunoglobulin G1 Fc Fragment-Tagged Human Opioid Receptor-Like Receptor Retains the Ability to Inhibit cAMP Accumulation
Biological Signals and Receptors, v. 9, (5), September-October 2000, p. 240-247
Yung, Ying; Tsim, Karl Wah Keung; Pei, Gang; Wong, Yung Hou
Species identification of Radix Astragali (Huangqi) by DNA sequence of its 5S-rRNA spacer domain
Phytochemistry, v. 54, (4), 2000, Jun, p. 363-368
Ma, Xiaoqiang; Duan, Jinao; Zhu, Dayuan; Dong, Tina Tingxia; Tsim, Karl Wah Keung
The cAMP-dependent protein kinase mediates the expression of AChE in chick myotubes
NeuroReport, v. 11, (4), 2000, MAR 20, p. 801-806
Choi, Roy Chi Yan; Siow, Nina Lam; Zhu, SQ; Tsim, Karl Wah Keung
The promoter of human acetylcholinesterase is activated by a cyclic adenosine 3 `,5 `-monophosphate-dependent pathway in cultured NG108-15 neuroblastoma cells
Neuroscience Letters, v. 288, (1), 2000, JUL 7, p. 81-85
Wan, DCC; Choi, Roy Chi Yan; Siow, Nina Lam; Tsim, Karl Wah Keung
贝母的分子生物学鉴定方法的研究
药学学报=Acta Pharmaceutica Sinica, v. 35, (4), 2000, p. 309-312
蔡朝晖; 李 萍; 董婷霞; 詹华强
Article 5
A cysteine-rich form of Xenopus neuregulin induces the expression of acetylcholine receptors in cultured myotubes
Molecular and Cellular Neuroscience, v. 13, (6), June 1999, p. 415-429
Yang, Jiefei; Zhou, Hong; Choi, Roy Chi Yan; Ip, Nancy Yuk-Yu; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung
Lack of allelic association of dopamine D4 receptor gene polymorphisms with Parkinson's disease in a Chinese population
Movement disorders, v. 14, (2), 1999, Mar, p. 225-229
Wan, David Chi Cheong; Law, Lapkay; Ip, Denis; Cheung, W. T.; Ho, Walter; Tsim, Karl Wah Keung; Kay, Richard; Woo, Jean; Pang, Chipui
Molecular diversity of 5S-rRNA spacer domain in Fritillaria species revealed by PCR analysis
Planta medica, v. 65, (4), 1999, May, p. 360-364
Cai, Zhaohui; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung
Xenopus muscle-specific kinase: molecular cloning and prominent expression in neural tissues during early embryonic development
European Journal of Neuroscience, v. 11, (2), February 1999, p. 373-382
Fu, Amy Kit Yu; Smith, Frances D.; Zhou, Hong; Chu, Apple H.; Tsim, Karl Wah Keung; Peng, Benjamin H.; Ip, Nancy Yuk-Yu
蒲圻贝母组织培养鳞茎形成过程中生理生化变化研究
武汉植物学研究, v. 1999, (04), 1999, p. 314-318
蔡朝晖; 李萍; 李会军; 高山林; 董婷霞; 詹华强
Article 3
Cloning of cDNAs encoding Xenopus neuregulin: expression in myotomal muscle during embryo development
Molecular Brain Research, v. 58, (1-2), July 1998, p. 69-73
Yang, Jiefei; Zhou, Hong; Pun, San; Ip, Nancy Yuk-Yu; Peng, H. Benjamin; Tsim, Karl Wah Keung
Over-expression of acetylcholinesterase stimulates the expression of agrin in NG108-15 cells
Neuroscience Letters, v. 248, (1), 1998, MAY 22, p. 17-20
Choi, Roy Chi Yan; Yam, SCY; Hui, BD; Wan, DCC; Tsim, Karl Wah Keung
The calcitonin gene-related peptide-induced acetylcholinesterase synthesis in cultured chick myotubes is mediated by cyclic AMP
Journal of Neurochemistry, v. 71, (1), July 1998, p. 152-160
Choi, Roy Chi Yan; Yung, Lisa Ying; Dong, Tina Ting Xia; Wan, David C.C.; Wong, Yung Hou; Tsim, Karl Wah Keung
Article 12
A globular, not a symmetric, form of acetylcholinesterase is expressed in chick motor neurons: Down-regulation toward maturity and after denervation
Journal of neurochemistry, v. 68, (2), 1997, FEB, p. 479-487
Tsim, Karl Wah Keung; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wan, DCC
A role of midkine in the development of the neuromuscular junction
Molecular and Cellular Neurosciences, v. 10, (1-2), 1997, p. 56-70
Zhou, Hong; Muramatsu, Takashi; Halfter, Willi M.; Tsim, Karl Wah Keung; Peng, H. Benjamin
Agrin-deficient myotube retains its acetylcholine receptor aggregation ability when challenged with agrin
Journal of Neurochemistry, v. 69, (6), December 1997, p. 2555-2563
Pun, San; Ng, Yu Pong; Yang, Jiefei; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung
Antisense agrin cDNA transfection blocks neuroblastoma cell-induced acetylcholine receptor aggregation when co-cultured with myotubes
Molecular and Cellular Neurosciences, v. 10, (1-2), 1997, p. 87-99
Pun, San; Tsim, Karl Wah Keung
Chick muscle expresses various ARIA isoforms: Regulation during development, denervation, and regeneration
Molecular and Cellular Neurosciences, v. 9, (2), 1997, p. 132-143
Ng, Yu Pong; Pun, San; Yang, Jiefei; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung
Denervation decreases the ipsilateral expression of AChE in chick lumbaric motor neurons
Neuroscience Letters, v. 232, (2), 1997, AUG 29, p. 83-86
Wan, DCC; Ng, Yu Pong; Choi, Roy Chi Yan; Cheung, PWT; Dong, Tina Ting Xia; Tsim, Karl Wah Keung
Expression and localization of endothelin converting enzyme in rat vas deferens
Life sciences, v. 60, (18), 1997, Mar, p. 1605-1612
Wan, David Chi Cheong; Luk, Sandy Ka Shing; Tsim, Karl Wah Keung; Cheung, W. T.
Muscle-derived neurotrophin-3 increases the aggregation of acetylcholine receptors in neuron-muscle co-cultures
NeuroReport, v. 8, (18), December 1997, p. 3895-3900
Fu, Amy Kit Yu; Ip, Fanny Chun Fai; Lai, Kwok On; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
NG108-15 cells express neuregulin that induces AChR alpha-subunit synthesis in cultured myotubes
FEBS letters, v. 418, (3), 1997, Dec, p. 275-281
Pun, San; Yang, Jiefei; Ng, Yupong; Tsim, Karl Wah Keung
NG108-15 cells induce the expression of muscular acetylcholinesterase when co-cultured with myotubes
Neuroscience Letters, v. 236, (3), 1997, NOV 7, p. 167-170
Choi, Roy Chi Yan; Pun, S.; Dong, Tina Ting Xia; Wan, DCC; Tsim, Karl Wah Keung
The EGF-like domain of chick acetylcholine receptor-inducing activity (ARIA) contains its full biological activity
FEBS Letters, v. 403, (2), February 1997, p. 163-167
Yang, Jiefei; Ng, Yu Pong; Pun, San; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung
组培蒲圻贝母鳞茎形成过程中的同工酶电泳分析
中国中药杂志, v. 1997, (01), 1997
蔡朝晖; 高山林; 李萍; 董婷霞; 詹华强
Article 4
Calcitonin gene-related peptide increases the expression of acetylcholinesterase in cultured chick myotubes
Neuroscience Letters, v. 217, (2-3), 1996, OCT 18, p. 165-168
Choi, Roy Chi Yan; Leung, PWY; Dong, Tina Ting Xia; Wan, DCC; Tsim, Karl Wah Keung
Cerebellar granule cells express a specific isoform of agrin that lacks the acetylcholine receptor aggregating activity
FEBS letters, v. 379, (1), 1996, Jan, p. 63-68
So, K. L.; Pun, San; Wan, David Chi Cheong; Tsim, Karl Wah Keung
Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury
Journal of Neurochemistry, v. 67, (4), October 1996, p. 1607-1612
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
Extracellular and asymmetric forms of acetylcholinesterase are expressed on cholinergic and noncholinergic terminal neuropil of the developing chick retina
Cell and Tissue Research, v. 286, (1), 1996, Oct, p. 13-22
Rei?, Yvonne; Kr?ger, Stephan; Grassi, Jaques; Tsim, Karl Wah Keung; Willbold, Elmar; Layer, Paul Gottlob
Article 3
Cloning of the α component of the chick ciliary neurotrophic factor receptor: Developmental expression and down-regulation in denervated skeletal muscle
Journal of Neurochemistry, v. 65, (6), December 1995, p. 2393-2400
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu
Prenatal cocaine exposure revealed minimal postnatal changes in rat striatal dopamine D2 receptor sites and mRNA levels in the offspring
Molecular Neurobiology, v. 11, (1-3),p. 67-76
Stadlin, Alfreda; Choi, Heung Ling; Tsim, Karl Wah Keung; Tsang, David
Truncated form of pro-acetycholine receptor-inducing activity (ARIA) induces AChR α-subunit but not AChE transcripts in cultured chick myotubes
Neuroscience Letters, v. 198, (2), 1995, Sep, p. 107-110
Pun, San; Tsim, Karl Wah Keung
Article 3
cDNA that encodes active agrin
Neuron, v. 8, (4), 1992, Apr, p. 677-690
Tsim, Karl Wah Keung; Rüegg, Markus Andreas; Escher, Gérard; Kr?ger, Stephan; McMahan, Uel Jackson
The agrin gene codes for a family of basal lamina proteins that differ in function and distribution
Neuron, v. 8, (4), 1992, p. 691-699
Rüegg, Markus Andreas; Tsim, Karl Wah Keung; Horton, Sharon E.; Escher, Gérard; Kr?ger, Stephan; McMahan, Uel Jackson
Transcripts for the acetylcholine receptor and acetylcholine esterase show distribution differences in cultured chick muscle cells
Journal of Cell Biology, v. 118, (5), 1992, p. 1201-1212
Tsim, Karl Wah Keung; Greenberg, Ian B.; Rimer, Mendell; Randall, William R.; Salpeter, Miriam M.
Article 1
Regulation of acetylcholine receptors and acetylcholinesterase in the innervation of skeletal muscle
Neuromuscular Junction., v. 13, 2004, p. 499-514
Barnard, Eric A.; Beeson, David M W; Darlison, Mark G.; Moss, Stephen J.; Randall, W. R.; Tsim, Karl Wah Keung
Article 5
Acetylcholinesterase antibodies and thyroid autoimmunity
Clin Exp Immunol, v. 71, 1988, p. 96-99
Weetman, AP; Tse, CK; Randall, WR; Tsim, Karl Wah Keung; Barnard, EA
An asymmetric form of muscle acetylcholinesterase contains three subunit types and two enzymic activities in one molecule
Proceedings of the National Academy of Sciences of the United States of America, v. 85, (4), 1988, p. 1262-1266
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A.
Identification of a 17S asymmetric butyrylcholinesterase in chick muscle by monoclonal antibodies
Neurosci Lett, v. 86, 1988, p. 245-249
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A.
Monoclonal antibodies specific for the different subunits of asymmetric acetylcholinesterase from chick muscle.
Journal of Neurochem, v. 51, (1), 1988, p. 95-104
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A.
Synaptic acetylcholinesterase of chicken muscle changes during development from a hybrid to a homogeneous enzyme
EMBO Journal, v. 7, (8), 1988, p. 2451-2456
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A.
Article 1
Monoclonal antibodies against chicken brain acetylcholinesterase: their use in immunopurification and immunochemistry to demonstrate allelic variants of the enzyme
European Journal of Biochemistry, v. 164, (1), 1987, p. 95-102
Randall, William R.; Tsim, Karl Wah Keung; Lai, Josephine; Barnard, Eric A.
Article 2
Prolactin receptor in rat liver: Sex difference in estrogenic stimulation and imprinting of the responsiveness to estrogen by neonatal androgen in male rats
Molecular and Cellular Endocrinology, v. 40, (2-3), p. 99-105
Tsim, Karl Wah Keung; Pak, Raphael; Cheng, Christopher Hon Ki
The role of neonatal and pubertal gonadal hormones in regulating the sex dependence of the hepatic microsomal testosterone 5-reductase activity in the rat
Journal of Endocrinology, v. 106, (1), p. 71-79
Pak, Raphael; Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki
Article 3
Evidence for the involvement of essential sulphydryl group in rat hepatic lactogenic receptor but not in somatogenic receptor
Molecular and Cellular Endocrinology, v. 38, (1), 1984, p. 61-66
Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki
Pubertal gonadal hormones in modulating the testosterone dependency of hepatic aryl hydrocarbon hydroxylase in female rats
Pharmacology, v. 29, (3), 1984, p. 121-127
Pak, Raphael; Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki
Rat hepatic prolactin receptor: Pubertal exposure to sex steroid alters responsively to testosterone
Int J Peptide Protein Res, v. 23, 1984, p. 521-527
Cheng, Christopher H. K.; Tsim, Karl Wah Keung; Wai, M. K.
2016 37
2,3,7,8-Tetrachlorodibenzo-P-Dioxin Suppress AChE Activity in NGF Treated PC12 Cells
Chemico-Biological Interactions, v. 259, November 2016, p. 282-285
Xu, Li; Chen, Yangsheng; Xie, Heidi Qun Hui; Xu, Tuan; Fu, Hualing; Zhang, Songyan; Tsim, Karl Wah Keung; Bi, Wenchuan; Zhao, Bin Article
A Chinese Herbal Decoction, Reformulated from Kai-Xin-San, Relieves the Depression-like Symptoms in Stressed Rats and Induces Neurogenesis in Cultured Neurons
Scientific Reports, v. 6, July 2016, article number 30014
Yan, Lu; Hu, Qinghua; Mak, Marvin S.H.; Lou, Jianshu; Xu, Li; Bi, Wenchuan; Zhu, Yue; Wang, Huai You; Dong, Ting Xia; Tsim, Karl Wah Keung Article
A High Throughput Screening Platform for Skin Tuning Properties from Natural Products: Identification of Skin Tanning Compounds
Journal of Cosmetics, Dermatological Sciences and Applications, v. 6, (5), December 2016, p. 199-209
Chan, Kar Lun Gallant; Wu, Qiyun; Wong, Chun Fai; Fung, Hei Yiu; Lin, Xuyan; Lou, Jianshu; Dong, Tingxia; Tsim, Karl Wah Keung Article
Anxiety and Depression with Neurogenesis Defects in Exchange Protein Directly Activated by cAMP 2-Deficient Mice are Ameliorated by a Selective Serotonin Reuptake Inhibitor, Prozac
Translational Psychiatry, v. 6, (9), September 2016, article number e881
Zhou, L.; Ma, Sukling; Yeung, Patrick Ka Kit; Wong, Yung Hou; Tsim, Karl Wah Keung; So, K. F.; Lam, L.C.W.; Chung, S.K. Article
Asarone from Acori Tatarinowii Rhizoma Potentiates the Nerve Growth Factor-Induced Neuronal Differentiation in Cultured PC12 Cells: A Signaling Mediated by Protein Kinase A
PLoS ONE, v. 11, (9), September 2016, article number e0163337
Lam, Yin Ching; Chen, Jianping; Lam, Ting Wai; Wu, Qiyun; Yao, Ping; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung Article
Authentication of Acori Tatarinowii Rhizoma (Shi Chang Pu) and its Adulterants by Morphological Distinction, Chemical Composition and ITS Sequencing
Chinese Medicine, v. 11, (1), September 2016, Article number 41
Lam, Yin Ching; Ku, Chuen Fai; Wang, Huai You; Chan, Kar Lun Gallant; Yao, Ping; Lin, Huang Quan; Dong, Ting Xia; Zhang, Hong Jie; Tsim, Karl Wah Keung Article
Badiranji Buya Keli, a Traditional Uyghur Medicine, Induces Vasodilation in Rat Artery: Signaling Mediated by Nitric Oxide Production in Endothelial Cells
Phytotherapy Research, v. 30, (1), January 2016, p. 16-24
Miernisha, Abudureyimu; Bi, Wenchuan; Cheng, Kwan Wai; Xing, J.G.; Liu, Jian; Maiwulanjiang, Maitinuer; Aisa, Haji Akber Kber; Dong, Ting Xia; Lin, Huangquan; Huang, Y.; Tsim, Karl Wah Keung Article
Chemical and biological assessment of Jujube (Ziziphus jujuba)-containing herbal decoctions: Induction of erythropoietin expression in cultures
Journal of Chromatography B, v. 1026, July 2016, p. 254-262
Lam, Ting Wai; Chan, Pui Hei; Lee, Pinky Sum-chi; Lau, Kei Man; Kong, Yeung Yeung Ava; Gong, Amy Guo-wei; Xu, Miranda Li; Lam, Yin Ching; Dong, Tingxia; Lin, Huangquan; Tsim, Karl Wah Keung Article
Clivorine, an Otonecine Pyrrolizidine Alkaloid from Ligularia Species, Impairs Neuronal Differentiation via NGF-Induced Signaling Pathway in Cultured PC12 Cells
Phytomedicine, v. 23, (9), August 2016, p. 931-938
Xiong, Aizhen; Yan, Artemis Lu; Bi, Wenchuan; Lam, Yin Ching; Chan, Kar Lun Gallant; Lau, Kei May; Dong, Ting Xia; Lin, Huangquan; Yang, Li; Wang, Zhengtao; Tsim, Karl Wah Keung Article
Danggui Buxue Tang, a Chinese Herbal Decoction, Induces Nitric Oxide Production in Cultured Endothelial Cells: Probing Calycosin as a Key Player by Chemical Knock-out Approach
Journal of Research and Development, March 2016, S1:1
Gong, Guowei; Lam, Ting Wai; Zhang, Minglu; Deng, Junyang; Wang, Huaiyou; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung Article
Danggui Buxue Tang, Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, Induces Production of Nitric Oxide in Endothelial Cells: Signaling Mediated by Phosphorylation of ndothelial Nitric Oxide Synthase
Planta medica, v. 82, (5), March 2016, p. 418-423
Gong, Amy Guowei; Lau, Keiman; Zhang, Minglu; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Determination of hair ketamine cut-off value from Hong Kong ketamine users by LC-MS/MS analysis
Forensic Science International, v. 259, February 2016, p. 53-58
Leung, Ka Wing; Wong, Zack C.F.; Ho, Janet Y.M.; Yip, Ada W.S.; Ng, Jenny S.C.; Ip, Stanley P.H.; Ng, Winki Y.Y.; Ho, Karen K.L.; Duan, Ran; Zhu, Kevin Y.; Tsim, Karl Wah Keung Article
Expression of Globular form Acetylcholinesterase is not Altered in P2Y1R Knock-Out Mouse Brain
Chemico-Biological Interactions, v. 259, November 2016, p. 291-294
Cui, Di; Xu, Miranda Li; Liu, Yunle; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung; Bi, Wenchuan Article
Extract of Ziziphus jujuba Fruit (Jujube) Stimulates Expression of Enzymes Responsible for Heme Recycle via Anti-oxidant Response Element in Cultured Murine Macrophages
Phytotherapy Research, v. 30, (2), February 2016, p. 267-271
Chen, Jianping; Lam, Candy T.W.; Li, Zhonggui; Yao, Ping; Lin, Huangquan; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Ferulic Acid Orchestrates Anti-oxidation Properties of Danggui Buxue Tang, an Ancient Herbal Decoction: Elucidation by Chemical Knock-out Approach
PLoS ONE, v. 11, (11), November 2016, Article number e0165486
Gong, Amy Guo-wei; Huang, Yun; Wang, Huai You; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Indication of Nerve Growth Factor Binding Components from Herbal Extracts by HerboChip: A Platform for Drug Screening on a Chip
Chinese Medicine, v. 11, (1), July 2016, article number 34
Lee, Pinky Sum-chi; Zhang, Minglu; Yan, Lu; Lam, Yin Ching; Dong, Ting Xia; Lin, Huangquan; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung Article
Jujube-containing herbal decoctions induce neuronal differentiation and the expression of anti-oxidant enzymes in cultured PC12 cells
Journal of Ethnopharmacology, v. 188, July 2016, p. 275-283
Lam, Ting Wai; Gong, Amy Guo-wei; Lam, Yin Ching; Zhang, Laura M.; Chen, Jian-Ping; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung Article
Kai-Xin-San, a Standardized Traditional Chinese Medicine Formula, Up-Regulates the Expressions of Synaptic Proteins on Hippocampus of Chronic Mild Stress Induced Depressive Rats and Primary Cultured Rat Hippocampal Neuron
Journal of Ethnopharmacology, v. 193, December 2016, p. 423-432
Zhu, Yue; Duan, Xiuzhu; Cheng, Xiaoxuan; Cheng, Xiaonan; Li, Xu; Zhang, Liu; Liu, Pei; Su, Shulan; Duan, Jinao; Dong, Ting Xia; Tsim, Karl Wah Keung; Huang, Fei Article
Kai-Xin-San, a Traditional Chinese Medicine Formula, Induces Neuronal Differentiation of Cultured PC12 Cells: Modulating Neurotransmitter Regulation Enzymes and Potentiating NGF Inducing Neurite Outgrowth
Journal of Ethnopharmacology, v. 193, December 2016, p. 272-282
Zhu, Yue; Duan, Xiuzhu; Huang, Feiyu; Cheng, Xiaonan; Zhang, Liu; Liu, Pei; Shulan, Su; Duan, Jinao; Dong, Tinatingxia; Tsim, Karl Wah Keung Article
Neuroprotection Against Glutamate-Induced Excitotoxicity and Induction of Neurite Outgrowth by T-006, a Novel Multifunctional Derivative of Tetramethylpyrazine in Neuronal Cell Models
Neurochemistry International, v. 99, October 2016, p. 194-205
Xu, Daping; Chen, Haiyun; Mak, Shinghung; Hu, Shengquan; Tsim, Karl Wah Keung; Hu, Yuanjia; Sun, Yewei; Zhang, Gaoxiao; Wang, Yuqiang; Zhang, Zaijun; Han, Yifan Article
New Perspectives for Multi-Level Regulations of Neuronal Acetylcholinesterase by Dioxins
Chemico-Biological Interactions, v. 259, November 2016, p. 286-290
Xie, Heidi Qun Hui; Xu, Tuan; Chen, Yangsheng; Li, Yunping; Xia, Yingjie; Xu, Sherry Li; Wang, Lingyun; Tsim, Karl Wah Keung; Zhao, Bin Article
Quantitative Analysis of Nucleosides and Nucleobases in Deer Antler: Variation in Different Species
Pharmaceutica Analytica Acta, v. 7, (4), April 2016, article number 1000474
Bi, Dan; Zhang, L.M.L.; Tang, Wai Lun; Duan, Ran; Leung, Ka Wing; Dong, Tingxia; Wong, Yung Hou; Lin, Huangquan; Tsim, Karl Wah Keung Article
The Estrogenic Properties Of Danggui Buxue Tang, A Chinese Herbal Decoction, Are Triggered Predominantly By Calycosin In Mcf-7 Cells
Journal of ethnopharmacology, v. 189, Aug 2016, p. 81-89
Gong, Amy Guo-wei; Lau, Kei Man; Xu, Miranda Li; Lin, Huangquan; Dong, Ting Xia; Zheng, Ken Y.Z.; Zhao, K.J.; Tsim, Karl Wah Keung Article
Transcriptional activity of acetylcholinesterase gene is regulated by DNA methylation during C2C12 myogenesis Transcriptional activity of acetylcholinesterase gene is regulated by DNA methylation during C2C12 myogenesis
Brain research, v. 1642, July 2016, p. 114-123
Lau, Kei Man; Gong, Amy Guowei; Xu, Miranda Li; Lam, Ting Wai; Zhang, Minglu; Bi, Wenchuan; Cui, Di; Cheng, Wai Ming Anthony; Dong, Ting Xia; Tsim, Karl Wah Keung; Lin, Huangquan Article
Yu Ping Feng San Reverses Cisplatin-induced Multi-drug Resistance in Lung Cancer Cells via Regulating Drug Transporters and p62/TRAF6 Signalling
Scientific Reports, v. 6, August 2016, article number 31926
Lou, Jianshu; Yan, Lu; Bi, Wenchuan; Chan, Kar Lun Gallant; Wu, Qiyun; Liu, Yunle; Huang, Yun; Yao, Ping; Du, Crystal Y.Q.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Chemical and Biological Assessment of Ziziphus jujuba (Jujubes) Fruit from China of Different Geographical Sources and Developmental Stages: Chemical Composition and Possible Targets in Developing Health Food Products
Chinese Dates: A Traditional Functional Food / Dongheng Liu, Xingqian Ye, Yueming Jiang, editors. Boca Raton : CRC Press - Taylor & Francis Group, 2016, p. 83-97
Chen, Jianping; Lam, Ting Wai; Li, Zhonggui; Yao, Ping; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung Book chapter
Asarone from Acori Tatarinowii Rhizoma potentiates the nerve growth factor-induced neuronal differentiation in cultured PC12 cells: A signaling mediated by protein kinase A
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 12 August 2016
Lam, Yin Ching; Lin, Huangquan; Dong, Ting Xia; Yao, Ping; Lam, Ting Wai; Tsim, Karl Wah Keung Conference paper
Authentication of Acori Tatarinowii Rhizoma and its adulterants: Morphological distinction, chemical composition and DNA analysis
China Medicinal Materials Resources Conference, Xian, China, August 2016
Tsim, Karl Wah Keung; Lam, Yin Ching; Wang, Huaiyou; Dong, Tingxia Conference paper
Characterisation of spleen-meridian herbs using HPLC and UPLC/Q-TOF-MS ?ngerprints combined with principal component analysis
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, August 12th, 2016
Huang, Yun; Dong, Ting Xia; Yao, Ping; Zhou, Zhongyu; Lin, Huangquan; Tsim, Karl Wah Keung Conference paper
Chemical and biological assessment of Ziziphus jujube fruits from China: different geographical sources and development stages
第五届可食和药用植物资源及功能成分国际学术研讨会, 深圳, 2016年11月4日至11月7日
Tsim, Karl Wah Keung Conference paper
Chemical and biological assessment of Ziziphus jujube fruits from China: different geographical sources and development stages
China Medicinal Materials Resources Conference, Xian, China, 10 August, 2016
Tsim, Karl Wah Keung; Lam, Candy T.W.; Chen, Jianping; Zhou, Zhongyu; Gong, Guowei; Wang, Huaiyou; Yao, Ping; Duan, Ran Conference paper
Erythropoietin (Epo)-induced Signaling is Interfered by Acetylcholinesterase (AChE) in Erythroblasts and Neurons
Journal of Neurochemistry, v. 142, August 2017, p. 214-215
Liu, Yunle; Dong, Ting Xia; Xu, Miranda Li; Bi, Wenchuan; Luk, Wilson K.W.; Tsim, Karl Wah Keung Conference paper
Flavonoids Induce the Expression of Acetylcholinesterase in Cultured Osteoblasts
Chemico-Biological Interactions, v. 259, (B), 25 November 2016, p. 295-300
Xu, Miranda Li; Bi, Wenchuan; Kong, Yeung Yeung Ava; Dong, Ting Xia; Wong, Yung Hou; Tsim, Karl Wah Keung Conference paper
Numerical Simulations of Electrochemical Impedance Spectroscopy of Polymer-based Micro Electrochemical Sensors for Rapid Identification of DNA Molecules from Traditional Chinese Medicine
8th International Symposium on Microchemistry and Microsystems (ISMM 2016), Hong Kong, 30 May-1 June 2016
Gao, Bo; Xu, Wei; Ma, Shenhui; Lee, Yi-Kuen; Tsim, Karl Wah Keung; Dong, Tingxia; Lam, Kelly Y.C.; Zhang, Anping Conference paper
The Content of Arsenic (AS) in Cordyceps Sinensis
China Medicinal Materials Resources Conference, Xian, China, August 2016
Tsim, Karl Wah Keung; Dong, Tingxia; Duan, Ran; Tang, Wai Lun; Lam, Yin Ching Conference paper
The osteogenic properties of Danggui Buxue Tang, a Chinese herbal decoction containing Astragali Radix and Angelicae Sinensis Radix: transcriptomics analysis of specific chemical knock-out herbal decoction
International Conference on DNA Technology for Authentication, Quality Control and Conservation of Herbal Material, The Chinese University of Hong Kong, 12 - 14 December, 2016
Gong, Amy G.W.; Dong, Tina Ting-xia; Tsim, Karl Wah Keung Conference paper
Yu Ping Feng San, a Chinese herbal decoction, reverses cisplatin induced multi-drug resistance in non-small cell lung cancer
The 12th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, August 12th, 2016
Lou, Jianshu; Yao, Ping; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung Conference paper
2015 30
Authentication of Cordyceps sinensis by DNA Analyses: Comparison of ITS Sequence Analysis and RAPD-Derived Molecular Markers
Molecules, v. 20, (12), December 2015, p. 22454-22462
Lam, Yin Ching; Chan, Kar Lun Gallant; Xin, Guizhong; Xu, Hong; Ku, Chuen Fai; Chen, Jianping; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Calycosin orchestrates the functions of Danggui Buxue Tang, a Chinese herbal decoction composing of Astragali Radix and Angelica Sinensis Radix: An evaluation by using calycosin-knock out herbal extract
Journal of Ethnopharmacology, v. 168, June 2015, p. 150-157
Gong, Amy Guo-wei; Li, Ning; Lau, Kei Man; Lee, Pinky Sum-chi; Yan, Lu; Xu, Miranda Li; Lam, Ting Wai; Kong, Yeung Yeung Ava; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Edible Bird’s Nest, an Asian Health Food Supplement, Possesses Skin Lightening Activities: Identification of N-Acetylneuraminic Acid as Active Ingredient
Journal of Cosmetics, Dermatological Sciences and Applications, v. 5, (4), November 2015, article number 61507, p. 262-274
Chan, Kar Lun Gallant; Wong, Chun Fai; Lam, Yin Ching; Cheng, Kwan Wai; Zhang, Minglu; Lin, Huangquan; Dong, Tingxia; Tsim, Karl Wah Keung Article
Evaluation of Hemostatic and Anti-inflammatory Activities of Extracts from Different Lagochilus Species in Experimental Animals: Comparison of Different Extractives and Sources
Phytotherapy Research, v. 29, (1), 2015, p. 22-29
Jiao, Ying; Chen, Pei-Hua; Xiong, Aizhen; Wang, Zheng-Tao; Tsim, Karl Wah Keung; Chou, Gui-Xin; Xu, Hong Article
Fast Simultaneous Determination of 13 Nucleosides and Nucleobases in Cordyceps sinensis by UHPLC-ESI-MS/MS
Molecules, v. 20, (12), December 2015, p. 21816-21825
Zong, Shiyu; Han, Han; Wang, Bing; Li, Ning; Dong, Ting Xia; Zhang, Tong; Tsim, Karl Wah Keung Article
Fruit of Ziziphus jujuba (Jujube) at Two Stages of Maturity: Distinction by Metabolic Profiling and Biological Assessment
Journal of Agricultural and Food Chemistry, v. 63, (2), January 2015, p. 739-744
Chen, Jianping; Chan, Pui Hei; Lam, Candy Ting Wai; Li, Zhonggui; Lam, Kelly Yin Ching; Yao, Ping; Dong, Tina Ting Xia; Lin, Huangquan; Lam, Henry H N; Tsim, Karl Wah Keung Article
Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β
Journal of Molecular Neuroscience, v. 57, (4), December 2015, p. 561-570
Hu, Shengquan; Cui, Wei; Zhang, Zaijun; Mak, Shinghung; Xu, Daping; Li, Gang; Hu, Yuanjia; Wang, Yuqiang; Lee, Mingyuen; Tsim, Karl Wah Keung; Han, Yifan Article
Inhibiting beta-Amyloid-Associated Alzheimer's Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue
Journal of Molecular Neuroscience, v. 55, (4), March 2015, p. 1014-1021
Hu, Shengquan; Wang, Rui; Cui, Wei; Zhang, Zaijun; Mak, Shinghung; Xu, Daping; Choi, Chunglit; Tsim, Karl Wah Keung; Carlier, Paul R.; Lee, Mingyuen; Han, Yifan Article
Optimizing the Compatibility of Paired-Herb in an Ancient Chinese Herbal Decoction Kai-Xin-San in Activating Neurofilament Expression in Cultured PC12 Cells
Journal of Ethnopharmacology, v. 162, March 2015, p. 155-162
Yan, Lu; Xu, Sherry L.; Zhu, Kevin Y.; Lam, Yin Ching; Xin, Guizhong; Maiwulanjiang, Maitinuer; Li, Ning; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung Article
Reduced Expression of P2Y2 Receptor and Acetylcholinesterase at Neuromuscular Junction of P2Y1 Receptor Knock-out Mice
Journal of Molecular Neuroscience, v. 57, (3), November 2015, p. 446-451
Xu, Miranda Li; Bi, Wenchuan; Cheng, Kwan Wai; Mak, Shinghung; Yao, Ping; Luk, Wilson K.W.; Lau, Kei May; Cheng, Anthony W.M.; Tsim, Karl Wah Keung Article
Robust Neuritogenesis-Promoting Activity by Bis(heptyl)-Cognitin Through the Activation of alpha7-Nicotinic Acetylcholine Receptor/ERK Pathway
CNS Neuroscience and Therapeutics, v. 21, (6), June 2015, p. 520-529
Hu, Sheng-Quan; Cui, Wei; Mak, Shing-Hung; Choi, Chung-Lit; Hu, Yuan-Jia; Li, Gang; Tsim, Karl Wah Keung; Pang, Yuan-Ping; Han, Yi-Fan Article
The Volatile Oil of Nardostachyos Radix et Rhizoma Induces Endothelial Nitric Oxide Synthase Activity in HUVEC Cells
PLoS ONE, v. 10, (2), February 2015, article number e0116761
Maiwulanjiang, Maitinuer; Bi, Wenchuan; Lee, Pinky Sum-chi; Xin, Guizhong; Miernisha, Abudureyimu; Lau, Kei May; Xiong, Aizhen; Li, Ning; Dong, Ting Xia; Aisa, Haji Akber Kber; Tsim, Karl Wah Keung Article
The water extract of Angelica Sinensis Radix protects cultured PC12 cells against oxidative stress: suppression of reactive oxygen species and activation of anti-oxidant response elements
Oxidants and Antioxidants in Medical Science, v. 4, (1), 2015, p. 39-48
Lee, Pinky Sum-Chi; Yan, Artemis Lu; Gong, Amy Guo-Wei; Choi, Roy Chi-Yan; Lin, Huang-Quan; Tsim, Karl Wah Keung Article
Three N-Glycosylation Sites of Human Acetylcholinesterase Shares Similar Glycan Composition
Journal of Molecular Neuroscience, v. 57, (4), December 2015, p. 486-491
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Keiman; Bi, Wenchuan; Cheng, Anthony W.M.; Gong, Amy Guo-wei; Lin, Huangquan; Tsim, Karl Wah Keung Article
Yu Ping Feng San, an Ancient Chinese Herbal Decoction, Induces Gene Expression of Anti-viral Proteins and Inhibits Neuraminidase Activity
Phytotherapy Research, v. 29, (5), May 2015, p. 656-661
Du, Crystal Ying Qing; Zheng, Ken Y.Z.; Bi, Wenchuan; Dong, Ting Xia; Lin, Huangquan; Tsim, Karl Wah Keung Article
冬虫夏草中核苷类成分含量测定及HPLC指纹图谱研究
中药材=Journal of Chinese medicinal materials, v. 38, (5), May 2015, p. 952-956
王冰; 李宁; 董婷霞; 詹华强 Article
浸泡和酸性物质促进硫熏山药脱硫的研究
中药材, v. 38, (2), 2015, p. 271-274
郑玉忠; 谢丽玲; 乐智勇; 贺震旦; 詹华强; 曹晖 Article
硫熏山药对六味地黄丸中有效成分的影响
中国实验方剂学杂志=Chinese Journal of Experimental Traditional Medical Formulae, v. 21, (18), September 2015, p. 48-51
郑玉忠; 张振霞; 张勇; 刘亚群; 谢丽玲; 乐智勇; 贺震旦; 詹华强; 曹晖 Article
Chemical And Biological Studies Of Chinese Date Decoctions
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Lam, C.T.W.; Gong, Amy Guo-wei; Lam, K.Y.C.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Comparison Of Different Authentication Methods On Acori Tatarinowii Rhizoma
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Lam, K.Y.C.; Chan, Kar Lun Gallant; Xin, G.Z.; Lam, C.T.W.; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Cross‐talk of acetylcholinesterase with presenilin‐1
12th International Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12th ChE - PON6), Alicante, Spain, 27 September - 2 October 2015
Saez‐valero, Javier; Vidal, Cecilio J.; Campanari, Maria‐Letizia; Garcla‐ayllón, Maria‐Salud; Tsim, Karl Wah Keung Conference paper
Establishment Of Quality Control Standard For Edible Bird's Nest By Monoclonal Antibodies And Fingerprint
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Wong, Z.C.F.; Chan, Kar Lun Gallant; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Expression of P2Y receptor and acetylcholinesterase in muscle and brain of P2Y1 knock-out mice
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Cui, Di; Bi, Wenchuan; Xu, Miranda Li; Lau, Kitty K.m.; Luk, Wilson K.w.; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Functional and Quantitative PTM Proteomics in Study of Ethylene Signaling
11th Cross-straight Plant Biotechnology Symposium, Southern Central China Agricultural University. Wuhan, China, 2015
Li, Ning Conference paper
Low-Cost Portable Polymer-based Micro Electrochemical Sensor (PMES) System for Rapid Detection of the Cordyceps Sinensis
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Chemical and Biological Microsystems Society (CBMS), 2015, p. 1734-1736
Ma, Shenhui; Riaz, Kashif; Maslova, Anastasia; Gao, Bo; Alsuhaimi, Awadh O.; Lam, Yin Ching; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Zhang, Anping; Lee, Yi-Kuen Conference paper
Protective Functions Of Flavonoids In Nervous System Via Epo Regulation
The 11th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, 14 August 2015
Zheng, Xuan; Bi, Wenchuan; Yao, Ping; Yan, Lu; Luk, Wilson K.W.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The bone morphogenetic protein 2 (BMP2)-induced downstream signalings are altered by globular form AChE in cultured osteoblasts
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Bi, Wenchuan; Xu, Miranda Li; Lau, Kitty K.M.; Cui, Di; Lin, Huangquan; Ip, Paul S.P.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The Effect of N-glycosylation on the Enzymatic Activity, Stability and Transportation of Acetylcholinesterase
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Kei Man; Bi, Wenchuan; Cui, Di; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The N‐glycosylation of acetylcholinesterase regulates the enzymatic activity, stability and transport in a recombinant expression system
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonase, Elche, Spain, 27 September - 2 October 2015
Xu, Miranda Li; Luk, Wilson K.W.; Lau, Kitty K.M.; Bi, Wenchuan; Cui, Di; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Transcriptional regulation of acetylcholinesterase in different cells
12th International Meeting on Cholinesterases and 6th Conference on Paraoxonas, Elche, Spain, 27 September - 2 October 2015
Tsim, Karl Wah Keung; Luk, Wilson K.w.; Bi, Wenchuan; Yao, Ping; Lau, Kitty K.m.; Xu, Miranda Li; Cui, Di; Dong, Ting Xia Conference paper
2014 36
A Chemically Standardized Extract of Ziziphus jujuba Fruit (Jujube) Stimulates Expressions of Neurotrophic Factors and Anti-oxidant Enzymes in Cultured Astrocytes
Phytotherapy Research, v. 28, (11), 2014, p. 1727-1730
Chen, Jianping; Yan, Artemis Lu; Lam, Kelly Yin Ching; Lam, Candy Ting Wai; Li, Ning; Yao, Ping; Xiong, Aizhen; Dong, Tingxia; Tsim, Karl Wah Keung Article
A Standardized Extract of the Fruit of Ziziphus jujuba (Jujube) Induces Neuronal Differentiation of Cultured PC12 Cells: A Signaling Mediated by Protein Kinase A
Journal of Agricultural and Food Chemistry, v.62, (8), 2014, Feb, p. 1890-1897
Chen, Jianping; Maiwulanjiang, Maitinuer; Lam, Yin Ching; Zhang, Wendyli; Zhan, Yaxian; Lam, Ting Wai; Xu, Li; Zhu, Kevin Yue; Yao, Ping; Lau, David Tai Wai; Dong, Tingxia; Tsim, Karl Wah Keung Article
Acetylcholinesterase Protein Level Is Preserved in the Alzheimer's Brain
Journal of Molecular Neuroscience, v. 53, (3), June 2014, p. 446-453
Campanari, Maria-Letizia; Garcia-Ayllon, Maria-Salud; Blazquez-Llorca, Lidia; Luk, Wilson K.W.; Tsim, Karl Wah Keung; Saez-Valero, Javier Article
Alkaloids of Linderae Radix Suppressed the Lipopolysaccharide-induced Expression of Cytokines in Cultured Macrophage RAW 264.7 cells
TANG: Humanitas Medicine, v. 4, (4), 2014
Chou, Jiyao; Lam, Yin Ching; Chen, Jianping; Yao, Ping; Dong, Tingxia; Xiong, Aizhen; Chou, Guixin; Wang, Zhengtao; Tsim, Karl Wah Keung Article
An application of target profiling analyses in the hepatotoxicity assessment of herbal medicines: comparative characteristic fingerprint and bile acid profiling of Senecio vulgaris L. and Senecio scandens Buch.-Ham
Analytical and Bioanalytical Chemistry, v. 406, (29), November 2014, p. 7715-7727
Xiong, Aizhen; Fang, Lianxiang; Yang, Xiao; Yang, Fan; Qi, Meng; Kang, Hong; Yang, Li; Tsim, Karl Wah Keung; Wang, Zhengtao Article
Characterizations of Cholinesterases in Golden Apple Snail (Pomacea canaliculata)
Journal of Molecular Neuroscience, v. 53, (3), 2014, p. 424-428
Zou, Xiang-Hui; Xie, Heidi Qun-Hui; Zha, Guang-Cai; Chen, Vicky Ping; Sun, Yan-Jie; Zheng, Yu-Zhong; Tsim, Karl Wah Keung; Dong, Tina Ting-Xia; Choi, Roy Chi-Yan; Luk, Wilson Kin-Wai Article
Ferulic acid enhances the chemical and biological properties of Astragali Radix: A stimulator for danggui buxue tang, an ancient chinese herbal decoction
Planta Medica, v. 80, (2-3), February 2014, p. 159-164
Zheng, Ken Yu Zhong; Zhang, Zhenxia; Du, Crystal Ying Qing; Zhang, Wendyli; Bi, Cathy Wen Chuan; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Functions of Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, in Uterus and Liver are Both Estrogen Receptor-Dependent and -Independent
Evidence-based Complementary and Alternative Medicine, v. 2014, 2014, article number 438531
Zierau, Oliver; Zheng, Ken Yuzhong; Papke, Anja; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Vollmer, Guenter Article
Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture
Evidence-based Complementary and Alternative Medicine, v. 2014, 2014, article number 608721
Zhang, Wendy Li; Chen, Jian-Ping; Lam, Kelly Yin-Ching; Zhan, Janis Ya-Xian; Yao, Ping; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung Article
Identification of Angelica oil as a suppressor for the biological properties of Danggui Buxue tang: A Chinese herbal decoction composes of Astragali Radix and Angelica Sinensis Radix
Journal of Ethnopharmacology, v. 154, (3), July 2014, p. 825-831
Zhan, Janis Ya-xian; Zheng, Ken Yu-zhong; Zhang, Wendy Li; Chen, Jian-ping; Yao, Ping; Bi, Cathy Wen-chuan; Dong, Tina Ting-xia; Tsim, Karl Wah Keung Article
Metabolomic and Genomic Evidence for Compromised Bile Acid Homeostasis by Senecionine, a Hepatotoxic Pyrrolizidine Alkaloid
Chemical Research in Toxicology, v. 27, (5), May 2014, p. 775-786
Xiong, Aizhen; Yang, Fan; Fang, Lianxiang; Yang, Li; He, Yuqi; Wan, Yvonne Yu-Jui; Xu, Ying; Qi, Meng; Wang, Xiuli; Yu, Kate; Tsim, Karl Wah Keung; Wang, Zhengtao Article
Metabonomic Analysis of Water Extracts from Different Angelica Roots by 1H-Nuclear Magnetic Resonance Spectroscopy
Molecules, v. 19, (3), 2014, p. 3460-3470
Chan, Pui Hei Nicholas; Zhang, Wendy L.; Lau, Chungho; Cheung, Chi Yuen; Keun, Hector C.; Tsim, Karl Wah Keung; Lam, Henry H N Article
Presenilin-1 Influences Processing of the Acetylcholinesterase Membrane Ancho PRiMA
Neurobiology of Aging, v. 35, (7), July 2014, p. 1526-1536
Garcia-Ayllon, Maria-Salud; Campanari, Maria-Letizia; Montenegro, Maria-Fernanda; Cuchillo-Ibanez, Inmaculada; Belbin, Olivia; Lleo, Alberto; Tsim, Karl Wah Keung; Vidal, Cecilio J.; Saez-Valero, Javier Article
Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by 1H-NMR Metabolic Profiling
Evidence-Based Complementary and Alternative Medicine, v. 2014, 2014, article number 567893
Chan, Pui Hei; Zhang, Wendy L.; Cheung, Chi Yuen; Tsim, Karl W.K.; Lam, Henry Article
Quantification of the Transcripts Encoding Different Forms of AChE in Various Cell Types: Real-Time PCR Coupled with Standards in Revealing the Copy Number
Journal of Molecular Neuroscience, v. 53, (3), July 2014, p. 461-468
Bi, Wenchuan; Luk, Wilson K.W.; Campanari, Maria-Letizia; Liu, Yuen H.; Xu, Li; Lau, Kei May; Xu, Miranda Li; Choi, Chi Yan; Saez-valero, Javier; Tsim, Karl Wah Keung Article
Rapid identification of plant materials by wooden-tip electrospray ionization mass spectrometry and a strategy to differentiate the bulbs of Fritillaria
Analytica Chimica Acta, v. 820, April 2014, p. 84-91
Xin, Guizhong; Hu, Bin; Shi, Zi Qi; Lam, Yin Ching; Dong, Ting Xia; Li, Ping; Yao, Zhong Ping; Tsim, Karl Wah Keung Article
Sunitinib Produces Neuroprotective Effect Via Inhibiting Nitric Oxide Overproduction
CNS Neuroscience and Therapeutics, v. 20, (3), March 2014, p. 244-252
Cui, Wei; Zhang, Zai-Jun; Hu, Sheng-Quan; Mak, Shing-Hung; Xu, Da-Ping; Choi, Chung-Lit; Wang, Yu-Qiang; Tsim, Karl Wah Keung; Lee, Ming-Yuen; Rong, Jian-Hui; Han, Yi-Fan Article
Synergistic Inhibition on Acetylcholinesterase by the Combination of Berberine and Palmatine Originally Isolated from Chinese Medicinal Herbs
Journal of Molecular Neuroscience, v. 53, (3), 2014, p. 511-516
Mak, Shinghung; Luk, Wilson W.K.; Cui, Wei; Hu, Shengquan; Tsim, Karl Wah Keung; Han, Yifan Article
The Extract of Ziziphus jujuba Fruit (Jujube) Induces Expression of Erythropoietin Via Hypoxia-Inducible Factor-1α in Cultured Hep3B Cells
Planta Medica, v. 80, (17), September 2014, p. 1622-1627
Chen, Jianping; Lam, Ting Wai; Kong, Yeung Yeung Ava; Zhang, Li Wendy; Zhan, Yaxian; Bi, Wenchuan; Chan, Kar Lun Gallant; Lam, Yin Ching; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Article
The Standardized Extract of Ziziphus jujuba Fruit (Jujube) Regulates Pro-inflammatory Cytokine Expression in Cultured Murine Macrophages: Suppression of Lipopolysaccharide-stimulated NF-kappa B Activity
Phytotherapy research : PTR, v. 28, (10), October 2014, p. 1527-1532
Chen, Jianping; Du, Crystal Yingqing; Lam, Kelly Yin Ching; Zhang, Wendy L.; Lam, Candy Ting Wai; Yan, Artemis Lu; Yao, Ping; Lau, David Tai Wai; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The sulfur-fumigation reduces chemical composition and biological properties of Angelicae sinensis radix
Phytomedicine, v. 21, (11), September 2014, p. 1318-1324
Zhan, Janis Ya-Xian; Yao, Ping; Bi, Cathy Wen-Chuan; Zheng, Ken Yu-zhong; Zhang, Wendy Li; Chen, Jian-Ping; Dong, Tina Ting-Xia; Su, Zi-Ren; Tsim, Karl Wah Keung Article
The volatile oil of Nardostachyos Radix et Rhizoma inhibits the oxidative stress-induced cell injury via reactive oxygen species scavenging and Akt activation in H9c2 cardiomyocyte
Journal of Ethnopharmacology, v. 153, (2), April 2014, p. 491-498
Maiwulanjiang, Maitinuer; Chen, Jianping; Xin, Guizhong; Gong, Amy G.W.; Miernisha, Abudureyimu; Du, Crystal Y.Q.; Lau, Keiman; Lee, Pinky S.C.; Chen, Jihang; Dong, Tina T.X.; Aisa, Haji A.; Tsim, Karl Wah Keung Article
UPLC-MS/MS法测定吸毒者头发中10种毒品代谢物的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 34, (3), 2014, p. 516-522
谢普; 王铁杰; 殷果; 闫研; 丁振浩; 肖丽和; 詹华强; 梁嘉荣; 李璐; 孙新珺; 毕开顺 Article
Yu Ping Feng San, an Ancient Chinese Herbal Decoction, Regulates the Expression of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 and the Activity of Intestinal Alkaline Phosphatase in Cultures
PLoS ONE, v. 9, (6), June 2014, article number e100382
Du, Crystal Ying Qing; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David Tai Wai; Tsim, Karl Wah Keung Article
中药冬虫夏草的鉴别研究
中国药学杂志=Chinese Pharmaceutical Journal, v. 49, (4), February 2014, p. 283-286
徐红; 董婷霞; 赵奎君; 陈嘉伦; 林燕靖; 詹华强; 王峥涛 Article
紫草药材的HPLC指纹图谱研究及其β-乙酰氧基异戊酰阿卡宁的含量测定
China Pharmacy, (3), 2014, p. 262-265
Miernisha, A.; Dong, Ting Xia; Guo, A.J.Y.; Aisa, HA; Tsim, Karl Wah Keung Article
紫草药材的HPLC指纹图谱研究及其β-乙酰氧基异戊酰阿卡宁的含量测定
中国药房=China Pharmacy, v. 25, (3), 2014, p. 262-265
米尔尼沙·阿不都热依木; 董婷霞; 郭江扬; 阿吉·艾克拜尔艾萨; 詹华强 Article
Authenication of cervi cornu pantotrichum by microscopic and dna analysis
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Lam, Yin Ching; Xu, H.; Chan, Kar Lun Gallant; Xin, GZ; Yao, Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Flavonoids originated from Chinese medicines possess neuroprotective effects on cultured neurons: Development of health food supplements in preventing Alzheimer's disease
Chinese Chemical Society 10th National Symposium on Natural Organic Chemistry, Guangzhou, China, 21-23 November 2014
Tsim, Karl Wah Keung Conference paper
Optimizing the compatibility of paired-herb in an ancient chinses herbal decoction kai-xin-san in activating neurofilamment expression in cultured pc12 cells
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Yan, Lu; Xu, SL; Zhu, Kevin Y.; Lam, Yin Ching; Xin, GZ; Li, N.; Yao, Ping; Lin, Huangquan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Quality Control of Cooking Oils by GC-MS Profiling and Spectral Fingerprinting
62nd ASMS Conference on Mass Spectrometry and Allied Topics 2014, Baltimore, MD, USA, 15-19 June 2014
Chan, Pui Hei Nicholas; Zhu, Y.; Tsim, Karl Wah Keung; Lam, Henry H N Conference paper
Resource development and biological evaluation: Nardostachyos Radix et Rhizoma and Dracocephali Moldavicae Herba
The 2014 International Seminar for Chinese Medicine & National Medical Resource and 11th Academic Annual Conference for Professional Committee of Natural Medicine Resource of China Society of National Resource, Nanjing, China, 15-18 October 2014
Tsim, Karl Wah Keung Conference paper
The chemical and biological studies of zao tang and jujube extract
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Lam, Ting Wai; Chen, Jianping; Yan, Lu; Lam, Yin Ching; Chan, Pui Hei Nicholas; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The pharmacological properties of calycosin-depleted danggui buxue tang
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Gong, Amy Guo-wei; Li, N.; Gao, QG; Yao, Ping; Lin, Huangquan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
The Quality Assurance of Edible Bird's Nest
Edible Bird Nest Industry Conference 2014, Putrajaya, Malaysia, 24-27 November 2014
Tsim, Karl Wah Keung Conference paper
The role of flavonoids, derived from traditional chinese medicine, in the production of erythropoetin
2014 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2014
Men, WX; Xu, SL; Lin, HQ; Dong, TTX; Tsim, Karl Wah Keung Conference paper
2013 28
Activation of UTP-Sensitive P2Y(2) Receptor Induces the Expression of Cholinergic Genes in Cultured Cortical Neurons: A Signaling Cascade Triggered by Ca2+ Mobilization and Extracellular Regulated Kinase Phosphorylation
Molecular Pharmacology, v. 84, (1), 2013, p. 50-61
Choi, Roy Chi Yan; Chu, Glanice K.Y.; Siow, Nina Lam; Yung, Amanda W.Y.; Yung, Lisa Ying; Lee, Pinky S.C.; Lo, Christopher C.W.; Simon, Joseph; Dong, Tina Ting Xia; Barnard, Eric A.; Tsim, Karl Wah Keung Article
Analysis of HPLC fingerprints and determination of isofraxidin and rosmarinic acid of Sarcandrae Herba from Sarcandra glabra (Thunb.) Nakai
China Pharmacy, v. 24, (47), 2013, p. 4472-4474
Tang, W.L.R.; Ng, Y.Y.; Bi, Dan; Duan, Ran; Tsim, Karl Wah Keung; Dong, Tina Ting Xia Article
Can Hedysari Radix replace Astragali Radix in Danggui Buxue Tang, a Chinese herbal decoction for woman aliment?
Phytomedicine, v. 20, (12), September 2013, p. 1076-1081
Zhang, Wendy Li; Choi, Roy Chi-Yan; Zhan, Janis Ya-Xian; Chen, Jian-Ping; Luk, Wilson Kin-Wai; Yao, Ping; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung Article
Chemical and Biological Assessment of Angelica Roots from Different Cultivated Regions in a Chinese Herbal Decoction Danggui Buxue Tang
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 483286
Zhang, Wendy L.; Zheng, Ken Y.Z.; Zhu, Kevin Y.; Zhan, Janis Y.X.; Bi, Cathy W.C.; Chen, J.P.; Dong, Tina T.X.; Choi, Roy C.Y.; Lau, David T.W.; Tsim, Karl W.K. Article
Chemical and Biological Assessment of Ziziphus jujuba Fruits from China: Different Geographical Sources and Developmental Stages
Journal of agricultural and food chemistry, v.61, (30), July 2013
Chen, Jianping; Li, Zhonggui; Maiwulanjiang, Maitinuer; Zhang, Wendy Li; Zhan, Janis Yaxian; Lam, Candy Ting Wai; Zhu, Kevin Yue; Yao, Ping; Choi, Chiyan; Lau, Taiwai; Dong, Tingxia; Tsim, Karl Wah Keung Article
Chemical changes of Angelicae Sinensis Radix and Chuanxiong Rhizoma by wine treatment: chemical profiling and marker selection by gas chromatography coupled with triple quadrupole mass spectrometry
Chinese Medicine (United Kingdom), v. 8, (1), June 2013, article number 12
Zhan, Janis Ya-Xian; Zhang, Wendy Li; Zheng, Ken Yu-zhong; Zhu, Kevin Yue; Chen, Jian-ping; Chan, Pui-Hei; Dong, Tina Ting-xia; Choi, Roy Chi-yan; Lam, Henry H N; Tsim, Karl Wah Keung; Lau, David Tai-wai Article
Chemical fingerprinting and quantitative analysis of two common Gleditsia sinensis fruits using HPLC-DAD
Acta Pharmaceutica, v. 63, (4), December 2013, p. 505-515
Chen, Jianping; Li, Zhonggui; Zheng, Ken Y.Z.; Guo, Ava J.Y.; Zhu, Kevin Y.; Zhang, Wendy L.; Zhan, Janis Y.X.; Dong, Tina T.X.; Su, Ziren; Tsim, Karl W.K. Article
Determination of free N-acetylneuraminic acid in edible bird nest: A development of chemical marker for quality control
Journal of Ethnobiology and Traditional Medicine, v. 120, October 2013, p. 620-628
Chan, Kar Lun Gallant; Zheng, Ken Yu Zhong; Zhu, Kevin Yue; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Distribution and expression of Kirre, an IgSF molecule, during postnatal development of rat cerebellum
Neuroscience Letters, v. 543, May 2013, p. 22-26
Kong, Lingwei; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Jing, Naihe; Nakayama, Don K.; Wang, Zhongbiao Article
Dual-Index Evaluation of Character Changes in Panax ginseng C. A. Mey Stored in Different Conditions
Journal of Agricultural and Food Chemistry, v. 61, (26), July 2013, p. 6568-6573
Li, Chen-yang; Lau, David Tai-wai; Dong, Tina Ting-xia; Zhang, Jian; Choi, Roy Chi-yan; Wu, Hai-qiang; Wang, Li-yan; Hong, Rui-sha; Li, Shi-he; Song, Xun; Yu, Tian; Su, Wei-wei; Tsim, Karl Wah Keung; He, Zhen-dan Article
Expression of cAMP-responsive Element Binding Proteins (CREBs) in Fast- and Slow-twitch Muscles: A Signaling Pathway to Account for the Synaptic Expression of Collagen-tailed Subunit (ColQ) of Acetylcholinesterase at the Rat Neuromuscular Junction
Chemico-biological Interactions, v. 203, (1), March 2013, p. 282-286
Choi, Roy Chi Yan; Chen, Ping; Luk, Wilson K.W.; Yung, Wai Yi; Ng, Alice H.M.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Flavonoids Induce the Expression of Synaptic Proteins, Synaptotagmin, and Postsynaptic Density Protein-95 in Cultured Rat Cortical Neuron
Planta Medica, v. 79, (18), December 2013, p. 1710-1714
Xu, Sherry Li; Zhu, Kevin Y; Bi, Wenchuan; Choi, Chi Yan; Miernisha, Abudureyimu; Yan, Artemis Lu; Maiwulanjiang, Maitinuer; Men, Simon W.X.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Flavonoids Induce the Synthesis and Secretion of Neurotrophic Factors in Cultured Rat Astrocytes: A Signaling Response Mediated by Estrogen Receptor
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013-06, article number 127075
Xu, Li; Bi, Wenchuan; Choi, Chi Yan; Zhu, Kevin Y; Miernisha, Abudureyimu; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Flavonoids, Derived from Traditional Chinese Medicines, Show Roles in the Differentiation of Neurons: Possible Targets in Developing Health Food Products
Birth Defects Research Part C: Embryo Today: Reviews, v. 99, (4), December 2013, p. 292-299
Xu, Li; Zhu, Kevin Y; Bi, Wenchuan; Yan, Lu; Men, Simon W.X.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
HPLC法同时测定浮小麦中5-二十一烷基间苯二酚和亚油酸的含量
中国药房=China Pharmacy, v. 24, (3), 2013, p. 244-246
高明菊; 毕 丹; 孟 霜; TANG Wai-lun; 徐 畅; 詹华强; 董婷霞 Article
Importance of Wine-Treated Angelica Sinensis Radix in Si Wu Tang, a Traditional Herbal Formula for Treating Women's Ailments
Planta Medica, v. 79, (7), May 2013, p. 533-537
Zhan, Yaxian; Zheng, Ken Y.Z.; Zhu, Kevin Y; Zhang, Li Wendy; Bi, Wenchuan; Chen, Jianping; Du, Crystal Ying Qing; Dong, Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Article
Kai-Xin-San, a Chinese Herbal Decoction Containing Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria, Stimulates the Expression and Secretion of Neurotrophic Factors in Cultured Astrocytes
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 731385
Zhu, Kevin Yue; Xu, Sherry Li; Choi, Roy Chi-Yan; Yan, Artemis Lu; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung Article
Optimizing Combinations of Flavonoids Deriving from Astragali Radix in Activating the Regulatory Element of Erythropoietin by a Feedback System Control Scheme
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 541436
Yu, Hui; Zhang, Wendy Li; Ding, Xianting; Zheng, Ken Yu Zhong; Ho, Chih-Ming; Tsim, Karl Wah Keung; Lee, Yi-Kuen Article
Perimenopause Amelioration of a TCM Recipe Composed of Radix Astragali, Radix Angelicae Sinensis, and Folium Epimedii: An In Vivo Study on Natural Aging Rat Model
Evidence-based Complementary and Alternative Medicine, v. 2013, 2013, article number 747240
Su, Ji-Yan; Xie, Qing-Feng; Liu, Wei-Jin; Lai, Ping; Liu, Dan-Dan; Tang, Li-Hai; Dong, Tina Ting Xia; Su, Zi-Ren; Tsim, Karl Wah Keung; Lai, Xiao-Ping; Li, Kun-Yin Article
Song Bu Li Decoction, a Traditional Uyghur Medicine, Protects Cell Death by Regulation of Oxidative Stress and Differentiation in Cultured PC12 Cells
Evidence-Based Complementary and Alternative Medicine, v. 2013, 2013, article number 687958
Maiwulanjiang, Maitinuer; Zhu, Kevin Y.; Chen, Jianping; Abudureyimu miernisha; Xu, Li; Crystal y.q. du; Lau, Kei Man; Choi, Roy C.Y.; Dong, Tina T.X.; Aisa, Haji A.; Tsim, Karl W.K. Article
Surveillance of nitrite level in cubilose: Evaluation of removal method and proposed origin of contamination
Food Control, v. 34, (2), December 2013, p. 637-644
Chan, Gallant Kar Lun; Zhu, Kevinyue; Chou, David J.Y.; Guo, Ava Jiang Yang; Dong, Tinatingxia; Tsim, Karl Wah Keung Article
Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease
Evidence-Based Complementary and Alternative Medicine, v. 2013, 2013, article number 635694
Choi, Roy C.Y.; Zhu, Judy T.T.; Yung, Amanda W.Y.; Lee, Pinky S.C.; Xu, Sherry L.; Guo, Ava J.Y.; Zhu, Kevin Y.; Dong, Tina T.X.; Tsim, Karl W.K. Article
Yu Ping Feng San, an Ancient Chinese Herbal Decoction Containing Astragali Radix, Atractylodis Macrocephalae Rhizoma and Saposhnikoviae Radix, Regulates the Release of Cytokines in Murine Macrophages
PLoS ONE, v. 8, (11), November 2013, article number e78622
Du, Yingqing; Choi, Chi Yan; Zheng, Ken Yu Zhong; Dong, Ting Xia Tina; Lau, D.T.W.; Tsim, Karl Wah Keung Article
射干的质量标准研究
中国药房=China Pharmacy, v. 24, (11), 2013, p. 1023-1025
梁丽娟; 董婷霞; 詹华强; 赵奎君 Article
山豆根急性毒性实验研究
时珍国医国药=Lishizhen Medicine and Materia Medica Research, (4), 2013, p. 771-773
王平; 吴熙; 李俊鹏; 谢天柱; 邬晓鸥; 王晓炜; 文屏; 詹华强; 李军 Article
穿心莲质量标准研究
中国中医药信息杂志=Chinese Journal of Information on TCM, v. 20, (9), September 2013, p. 63-65
梁丽娟; 赵奎君; 董婷霞; 詹华强 Article
肿节风药材的HPLC指纹图谱研究及其异嗪皮啶与迷迭香酸的含量测定
中国药房=China Pharmacy, v. 24, (47), 2013, p. 4472-4474
邓伟麟; 吴莹莹; 毕丹; 段然; 詹华强; 董婷霞 Article
韭菜子的生药学研究
中国药房=China Pharmacy, v. 24, (3), 2013, p. 246-248
徐 红; 董婷霞; 林燕靖; 邓伟麟; 詹华强; 王峥涛 Article
2012 31
A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats
Evidence-based complementary and alternative medicine, v. 2012, 2012, Article number 149256
Zhu, Kevin Yue; Mao, Qing-Qiu; Ip, Siu-Po; Choi, Roy Chi-Yan; Dong, Tina Ting-Xia; Lau, David Tai-Wai; Tsim, Karl Wah Keung Article
Acetylcholinesterase: old questions and new developments
Frontiers in Molecular Neuroscience, v.5, 2013, Jan
Tsim, Karl Wah Keung; Soreq, Hermona Article
Application of Complementary and Alternative Medicine on Neurodegenerative Disorders: Current Status and Future Prospects
Evidence-based complementary and alternative medicine, v.2012, 2012, Article number 930908
Ip, Paul Siu-Po; Tsim, Karl Wah Keung; Chan, Kelvin; Bauer, Rudolf Article
Chemical and biological assessment of Angelica herbal decoction: Comparison of different preparations during historical applications
Phytomedicine, v. 19, (11), August 2012, p. 1042-1048
Zhang, Li Wendy; Zheng, Ken Y Z; Zhu, Kevin Y; Zhan, Yaxian; Bi, Wenchuan; Chen, Jianping; Du, Y.; Zhao, Kuijun; Lau, David T W; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Effect of a derived herbal recipe from an ancient Chinese formula, Danggui Buxue Tang, on ovariectomized rats
Journal of ethnopharmacology, v. 144, (3), December 2012, p. 567-575
Xie, Qing-Feng; Xie, Jian-Hui; Dong, Tina T.X.; Su, Ji-Yan; Cai, Da-Ke; Chen, Jian-Ping; Liu, Liang-Feng; Li, Yu-Cui; Lai, Xiao-Ping; Tsim, Karl Wah Keung; Su, Zi-Ren Article
Er Zhi Wan, an ancient herbal decoction for woman menopausal syndrome, activates the estrogenic response in cultured MCF-7 cells: An evaluation of compatibility in defining the optimized preparation method
Journal of ethnopharmacology, v. 143, (1), August 2012, p. 109-115
Xu, Hong; Su, Zi-Ren; Huang, Wen; Choi, Roy Chi-Yan; Zheng, Yu-Zhong; Lau, David Tai-Wai; Dong, Tina Ting-Xia; Wang, Zheng-Tao; Tsim, Karl Wah Keung Article
Fo Shou San, an Ancient Chinese Herbal Decoction, Protects Endothelial Function through Increasing Endothelial Nitric Oxide Synthase Activity
PLoS ONE, v. 7, (12), 2012, article no. e51670
Bi, Cathy W.C.; Xu, Li; Tian, Xiao Yu; Liu, Jian; Zheng, Ken Y.Z.; Lau, Chi Wai; Lau, David Tai Wai; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Huang, Yu; Tsim, Karl Wah Keung Article
HPLC-ELSD测定肉苁蓉及管花肉苁蓉中半乳糖醇含量
中国中医药信息杂志=Chinese Journal of Information on Traditional Chinese Medicine, v. 19, (8), 2012, p. 52-54
赵奎君; 梁丽娟; 毕丹; 董婷霞; 詹华强 Article
Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor
Evidence-Based Complementary and Alternative Medicine, v. 2012, 2012 article number 278273
Xu, Sherry L.; Choi, Roy C.Y.; Zhu, Kevin Y.; Leung, Ka-Wing; Guo, Ava J.Y.; Bi, Dan; Xu, Hong; Lau, David T.W.; Dong, Tina T.X.; Tsim, Karl W.K. Article
Kaempferol as a flavonoid induces osteoblastic differentiation via estrogen receptor signaling
Chinese Medicine, v. 7, (10), April 2012
Guo, Ava Jiangyang; Choi, Roy Chiyan; Zheng, Ken Yuzhong; Chen, Vicky Ping; Dong, Tina Tingxia; Wang, Zheng-Tao; Vollmer, Günter; Lau, David Taiwai; Tsim, Karl Wah Keung Article
Metabonomic analysis of water extracts from Chinese and American ginsengs by H-1 nuclear magnetic resonance: identification of chemical profile for quality control
Chinese medicine, v. 7, November 2012, Article number 25
Chan, Pui Hei; Zheng, Ken Y.Z.; Tsim, Karl Wah Keung; Lam, Henry H N Article
Microfluidic chip based nano liquid chromatography coupled to tandem mass spectrometry for the determination of abused drugs and metabolites in human hair
Analytical and bioanalytical chemistry, v. 402, (9), March 2012, p. 2805-2815
Zhu, Kevin Yue; Leung, Ka Wing; Ting, Annie K.L.; Wong, Zack C.F.; Ng, Winki Y.Y.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wang, Tiejie; Lau, David Tai Wai; Tsim, Karl Wah Keung Article
N-linked glycosylation of dimeric acetylcholinesterase in erythrocytes is essential for enzyme maturation and membrane targeting
The FEBS journal, v. 279, (17), September 2012, p. 3229-3239
Luk, Wilson Kin Wai; Chen, Vicky Ping; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase
Neuroscience Letters, v. 523, (1), August 2012, p. 71-75
Chan, Wallace Kin Bon; Chen, Vicky Ping; Luk, Wilson K.W.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Salidroside Stimulates the Accumulation of HIF-1 Alpha Protein Resulted in the Induction of EPO Expression: A Signaling via Blocking the Degradation Pathway in Kidney and Liver Cells
European Journal of Pharmacology, v. 679, (1-3), March 2012, p. 34-39
Zheng, Ken Y Z; Zhang, Zhenxia; Guo, A.J.Y.; Bi, Wenchuan; Zhu, Kevin Y; Xu, Li; Zhan, Yaxian; Lau, David T W; Dong, Ting Xia; Choi, Chi Yan; Tsim, Karl Wah Keung Article
The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: A synergistic action of an ancient herbal decoction Danggui Buxue Tang
Journal of pharmaceutical and biomedical analysis, v. 70, 2012, p. 671-679
Zheng, Ken Yu Zhong; Choi, Roy Chi Yan; Guo, Ava Jiang Yang; Bi, Cathy Wei Chuan; Zhu, Kevin Yue; Du, Crystal Ying Qing; Zhang, Zhen Xia; Lau, David Tai Wai; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress
Journal of ethnopharmacology, v. 139, (1), 2012, p. 214-220
Wang, T.; Choi, Roy Chi Yan; Li, J.; Bi, Cathy Wei Chuan; Ran, W.; Chen, X.; Dong, Tina Ting Xia; Bi, K.; Tsim, Karl Wah Keung Article
A flavonol aglycone isorhamnetin possesses neuronal differentiation activity in PC12 cells via the potentiation of NGF on neurite outgrowth
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Xu, SL; Choi, Roy Chi Yan; Zhu, KY; Guo, AJY; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Conference paper
An ancient paired-herbal decoction Fo Shou San, stimulates the blood and circulation functions
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Bi, CWC; Xu, SL; Lau, David Tai Wai; Choi, RCY; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Blood circulation effect of Angelica Radix Sinensis: anti-platelet aggregation and ENTPD gene regulation in human endothelial cells
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Ng, AHM; Choi, RCY; Lau, DTW; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Characterization of Acetylcholinesterase in Oyster, Crassostrea Gigas
11th International Meeting on Cholinesterases, Russia, 2012
Dong, Ting Xia; Sit, BHM; Chen, VP; Chan, Kin Bon Wallace; Luk, WKW; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Chromatographic fingerprint and determination of 5-heneicosylresorcinol and linoleic acid in Fructus Tritici Levis by HPLC
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Bi, Dan; Tang, RWL; Dong, Tina Ting Xia; Wang, ZT; Tsim, Karl Wah Keung Conference paper
Dynamic change of flavonoids during the preparation of Danggui Buxue Tang: an outcome of moderate boiling of Chinese herbal mixture
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Zhang, WL; Zheng, KYZ; Zhu, KY; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Investigation on the bioactive compounds of Chinese dates at two stages of maturity from young or historical trees
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Cheng, JP; Guo, AJY; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Conference paper
Mechanistic study of Yu Ping Feng San-mediated the inhibition of intestinal P-glycoprotein efflux transporter to enhance the bioavailability of Astragali Radix-derived calycosin in Caco-2 cell monolayers
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Du, CYQ; Zheng, KYZ; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Conference paper
Molecular Assembly of Acetylcholinesterase-H Form in Erythrocyte
11th International Meeting on Cholinesterases, Russia, 2012
Luk, WKW; Chen, VP; Choi, RCY; Chan, WKB; Tsim, Karl Wah Keung Conference paper
Neuroprotection effect of Angelica Sinensis Radix against oxidative stress in PC12 neurons
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Yung, AWY; Ng, AHM; Choi, RCY; Dong, Tina Ting Xia; Lau, DTW; Tsim, Karl Wah Keung Conference paper
Studies on pharmacognosy of Lonicerae Japonicae Flos
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Lam, KYC; Dong, Tiina Ting Xia; Wong, ZT; Tsim, Karl Wah Keung Conference paper
The study of the removal methods and the origin of nitrite in edible bird's nest
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Chan, GKL; Zheng, KYZ; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
The wine treatment on Angelicae Sinensis Radix and Chuanxiong Rhizoma: chemical distinction by using triple quadrupole gas chromatography
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, Chimna, 18-19 May 2012
Zhan, JYX; Zhang, WL; Zheng, KYZ; CHENG, JP; Dong, Tina Ting Xia; Lau, David T W; Tsim, Karl Wah Keung Conference paper
Traditional Uyghur medicine - Song Bu Li, a decoction from Nardostachyos Radix et Rhizoma: development of quality control parameter and evaluation of the biological functions
International Symposium on Sustainable Exploitation and Utilization of Medical Plant Resources in Lingnan, Chaozhou, China, 18-19 May 2012
Maitinuer, M.; Choi, RCY; Aisa, HA; Lau, DTW; Dong, Tina Ting Xia; Wang, ZT; Tsim, Karl Wah Keung Conference paper
2011 16
A Chinese Herbal Decoction, Danggui Buxue Tang, Stimulates Proliferation, Differentiation and Gene Expression of Cultured Osteosarcoma Cells: Genomic Approach to Reveal Specific Gene Activation
Evidence-based complementary and alternative medicine, (307548), 2011, p. 1-13
Choi, Roy Chi Yan; Gao, Qiu T.; Cheung, Anna Wing Han; Zhu, Judy Ting Ting; Lau, Faye T.C.; Li, Jun; Li, Winnie Z.M.; Chu, Glanice K.Y.; Duan, Ran; Cheung, Jerry K.H.; Ding, An W.; Zhao, Kui J.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Analysis of HPLC fingerprints of Fructus Aurantii from different habitats and contents of naringin, neohesperidin and synephrine
中国药学杂志, v. 46, (12), 2011, p. 955-959
Zhao, Kuijun; Zheng, Yuzhong; Dong, Tingxia; Tsim, Karl Wah Keung Article
Baicalin, a Flavone, Induces the Differentiation of Cultured Osteoblasts AN ACTION VIA THE Wnt/β-CATENIN SIGNALING PATHWAY
Journal of biological chemistry, v. 286, (32), August 2011, p. 27882-27893
Guo, Ava Jiang Yang; Choi, Roy Chi Yan; Cheung, Anna W.H.; Chen, Vicky Ping; Xu, Sherry Li; Dong, Tina Ting Xia; Chen, Ji J.; Tsim, Karl Wah Keung Article
Chemical and Biological Assessment of Angelicae Sinensis Radix after Processing with Wine: An Orthogonal Array Design To Reveal the Optimized Conditions
Journal of agricultural and food chemistry, v. 59, (11), June 2011, p. 6091-6098
Zhan, Janis Y.X.; Zheng, Ken Yu Zhong; Zhu, Kevin Yue; Bi, Cathy Wei Chuan; Zhang, Wendy L.; Du, Crystal Ying Qing; Fu, Qiang; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Lau, David Tai Wai Article
Chemical and DNA authentication of taste variants of Gynostemma pentaphyllum herbal tea
Food chemistry, v. 128, (1), September 2011, p. 70-80
Wu, Pui Kei; Tai, William C.S.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung; Zhou, Hua; Liu, Xin; Jiang, Zhi-Hong; Hsiao, W. L. Wendy Article
Expression of the IgSF protein Kirre in the rat central nervous system
Life sciences, v. 88, (13-14), 2011, p. 590-597
Kong, L.; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Wang, X.; Peng, G.; Xie, Z.; Tsim, Karl Wah Keung; Jing, N. Article
Flavonoids from Radix Astragali Induce the Expression of Erythropoietin in Cultured Cells: A Signaling Mediated via the Accumulation of Hypoxia-Inducible Factor-1α
Journal of Agricultural and Food Chemistry, v. 59, (5), 2011, p. 1697-1704
Zheng, Ken Y Z; Choi, Chi Yan; Cheung, Wing Han; Guo, A.J.Y.; Bi, Wenchuan; Zhu, Kevin Y; Fu, Qiang; Du, Yingqing; Zhang, Li Wendy; Zhan, Janis Y.X.; Duan, Ran; Lau, David T W; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Fo Shou San, an ancient herbal decoction prepared from Angelicae Sinensis Radix and Chuanxiong Rhizoma, induces erythropoietin expression: A signaling mediated by the reduced degradation of hypoxia-inducible factor in cultured liver cells
Planta medica, v. 78, (2), November 2011, p. 122-127
Bi, Wenchuan; Xu, Li; Zhang, Li Wendy; Zhan, Yaxian; Fu, Qiang; Zheng, Ken Y Z; Chen, Ping; Lau, David T W; Choi, Chi Yan; Wang, Tiejie; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Molecular Assembly and Biosynthesis of Acetylcholinesterase in Brain and Muscle: the Roles of t-peptide, FHB Domain, and N-linked Glycosylation
Frontiers in Molecular Neuroscience, v. 4, 2011, article number 36
Chen, Vicky P.; Luk, Wilson K.W.; Chan, Wallace K.B.; Leung, K. Wing; Guo, Ava J.Y.; Chan, Gallant K.L.; Xu, Sherry L.; Choi, Chi Yan; Tsim, Karl Wah Keung Article
Phenolic compounds from the rhizomes of dioscorea bulbifera
Chemistry & biodiversity, v. 8, (11), 2011, p. 2110-2116
Liu, Hai; Tsim, Karl Wah Keung; Chou, Guixin; Wang, Junming; Ji, Lili; Wang, Zhengtao Article
The Assembly of Proline-rich Membrane Anchor (PRiMA)-linked Acetylcholinesterase Enzyme GLYCOSYLATION IS REQUIRED FOR ENZYMATIC ACTIVITY BUT NOT FOR OLIGOMERIZATION
Journal of biological chemistry, v. 286, (38), September 2011, p. 32948-32961
Chen, Vicky P.; Choi, Roy C.Y.; Chan, Wallace K.B.; Leung, K. Wing; Guo, Ava J.Y.; Chan, Kar Lun Gallant; Luk, Wilson K.W.; Tsim, Karl Wah Keung Article
The establishment of a highly sensitive method in detecting ketamine and norketamine simultaneously in human hairs by HPLC-Chip-MS/MS
Forensic science international, v. 208, May 2011, p. 53-58
Zhu, Kevin Yue; Leung, Ka Wing; Ting, Annie K.L.; Wong, Zack Chun Fai; Fu, Qiang; Ng, Winki Y.Y.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wang, Tiejie; Lau, David Tai Wai; Tsim, Karl Wah Keung Article
The establishment of a sensitive method in determining different neurotransmitters simultaneously in rat brains by using liquid chromatography-electrospray tandem mass spectrometry
Journal of chromatography. B, v. 879, April 2011, p. 737-742
Zhu, Kevin Yue; Fu, Qiang; Leung, Ka Wing; Wong, Zack Chun Fai; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
The Extract of Rhodiolae Crenulatae Radix et Rhizoma Induces the Accumulation of HIF-1 alpha via Blocking the Degradation Pathway in Cultured Kidney Fibroblasts
Planta medica, v. 77, (9), June 2011, p. 894-899
Zheng, Ken Yu Zhong; Guo, Ava Jiang Yang; Bi, Cathy Wei Chuan; Zhu, Kevin Yue; Chan, Kar Lun Gallant; Fu, Qiang; Xu, Sherry Li; Zhan, Janis Y.Z.; Lau, David Tai Wai; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
不同产地枳壳药材HPLC指纹图谱及其柚皮苷、新橙皮苷和辛弗林含量分析
中国药学杂志=Chinese Pharmaceutical Journal, v. 2011, (12), 2011, p. 955-959
赵奎君; 郑玉忠; 董婷霞; 詹华强 Article
1H-NMR metabonomics analysis of Danggui Buxue Tang effects in HEK293T kidney cell lines
China Human Proteome Organization (CNHUPO) 7th Annual Congress, Hangzhou, China, 2011
Chan, Pui Hei Nicholas; Tsim, Karl Wah Keung; Lam, Henry H N Conference paper
2010 35
A Flavonol Glycoside, Isolated From Roots of Panax notoginseng, Reduces Amyloid-beta-Induced Neurotoxicity in Cultured Neurons: Signaling Transduction and Drug Development for Alzheimer's Disease
JOURNAL OF ALZHEIMERS DISEASE, v. 19, (3), 2010, p. 795-811
Choi, Roy Chi Yan; Zhu, Judy Ting Ting; Leung, Ka Wing; Chu, Glanice K.Y.; Xie, Heidi Qunhui; Chen, Vicky Ping; Zheng, Ken Yu Zhong; Lau, David Tai Wai; Dong, Tina Ting Xia; Chow, Peter C.Y.; Han, Yi-Fan; Wang, Zheng-Tao; Tsim, Karl Wah Keung Article
An induction effect of heat shock on the transcript of globular acetylcholinesterase in NG108-15 cells
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), 2010, SEP 6, p. 106-109
Chen, Vicky Ping; Xie, Heidi Qunhui; Chan, Wallace Kin Bon; Leung, Ka Wing; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Antihyperlipidemic Effect of Protodioscin, an Active Ingredient Isolated from the Rhizomes of Dioscorea nipponica
Planta Med., 76, 15, May 2010, p. 1642-1646
Wang, Tiejie; Choi, Chi Yan; Li, Jun; Bi, Wenchuan; Zang, Linquan; Liu, Zhongbo; Dong, Tingxia; Bi, Kaishun; Tsim, Karl Wah Keung Article
Anti-oxidative effects of the biennial flower of Panax notoginseng against H2O2-induced cytotoxicity in cultured PC12 cells
Chinese Medicine, v. 5, 2010
Choi, Roy Chi Yan; Jiang, Z.; Xie, Heidi Qunhui; Cheung, Anna Wing Han; Lau, David Tai Wai; Fu, Qiang; Dong, Tina Ting Xia; Chen, J.; Wang, Z.; Tsim, Karl Wah Keung Article
ATP induces synaptic gene expressions in cortical neurons: Transduction and transcription control via P2Y1 receptors
Molecular Pharmacology, v. 78, (6), 2010, p. 1059-1071
Siow, Nina Lam; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Kong, L.W.; Chu, G.K.Y.; Chan, Kar Lun Gallant; Simon, J.; Barnard, E.A.; Tsim, Karl Wah Keung Article
Differential gene expression profiling on the muscle of acetylcholinesterase knockout mice: A preliminary analysis
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), 2010, SEP 6, p. 120-123
Lin, Huang-Quan; Choi, Roy Chi Yan; Chan, Kam-Leung; Ip, Denis; Tsim, Karl Wah Keung; Wan, David Chi-cheong Article
Expression and Localization of PRiMA-Linked Globular Form Acetylcholinesterase in Vertebrate Neuromuscular Junctions
Journal of Molecular Neuroscience, v. 40, (1-2), January 2010, p. 40-46
Tsim, Karl Wah Keung; Leung, Ka Wing; Mok, Ka Wai; Chen, Ping; Zhu, Kevin Y; Zhu, Judy T T; Guo, A.J.Y.; Bi, Wenchuan; Zheng, Ken Y Z; Lau, David T W; Xie, Qunhui; Choi, Chi Yan Article
Fo Shou San, an Ancient Herbal Decoction Prepared from Rhizoma Chuanxiong and Radix Angelicae Sinensis, Stimulates the Production of Hemoglobin and Erythropoietin in Cultured Cells
Planta medica, v. 76, (14), October 2010, p. 1525-1529
Bi, Wenchuan; Xie, Qunhui; Xu, Li; Li, Jun; Cheung, Wing Han; Zhu, Judy T T; Zheng, Ken Y Z; Chen, Ping; Lau, David T W; Choi, Chi Yan; Wang, Tie Jie; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), September 2010, p. 246-248
Guo, Ava Jiang Yang; Xie, Heidi Qunhui; Choi, Roy Chi Yan; Zheng, Ken Yu Zhong; Bi, Wenchuan; Xu, Sherry Li; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Nerve Growth Factor-Induced Differentiation of PC12 Cells Is Accompanied by Elevated Adenylyl Cyclase Activity
NeuroSignals, v. 18, (1), September 2010, p. 32-42
Yung, H.S.; Lai, K.H.; Chow, Kevin B.S.; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung; Wong, Yung Hou; Wu, Zhenguo; Wise, Helen Article
PRiMA directs a restricted localization of tetrameric AChE at synapses
Chemico-biological interactions, v. 187, (1-3, Sp. Iss. SI), September 2010, p. 78-83
Xie, Qunhui; Leung, Ka Wing; Chen, Ping; Chan, Kar Lun Gallant; Xu, Li; Guo, A.J.Y.; Zhu, Kevin Y; Zheng, Ken Y Z; Bi, Weichuan; Zhan, Yaxian; Chan, Kin Bon Wallace; Choi, Chi Yan; Tsim, Karl Wah Keung Article
Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae
Journal of Separation Science, v. 33, (23-24), 2010, p. 3666-3674
Zhu, Kevin Yue; Fu, Qiang; Xie, Heidi Qunhui; Xu, S.L.; Cheung, Anna Wing Han; Zheng, Ken Yu Zhong; Luk, W.K.W.; Choi, Roy Chi Yan; Lau, David Tai Wai; Dong, Tina Ting Xia; Jiang, Z.Y.; Chen, J.J.; Tsim, Karl Wah Keung Article
Quality Evaluation of Radix Glehniae (Glehnia littoralis) by HPLC-DAD: Chromatographic Fingerprinting and Quantitative Analysis of the Herbs from Different Regions of China
Asian Journal of Traditional Medicines 2010, v. 5, (2), 2010, p. 40-48
Li, Jun; Cheung, Wing Han; Bi, Wenchuan; Duan, Ran; Zheng, Ken Y Z; Huang, Wen; Chen, Ji J.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Synthesis and Anti-inflammatory Activity of a Novel Series of 9,10-Dihydro-4H,8H-chromeno [8,7-e][1,3]oxazin-4-one Derivatives
Chemical Research in Chinese Universities, v. 26, (2), 2010, MAR 25, p. 268-271
Liu, Xiao-ping; Wang, Ying; Lan, Hui-yu; Song, Ai-hua; Tsim, Karl Wah Keung; Dong Tina, Ting-xia; Hu, Chun Article
Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons
Journal of Biological Chemistry, v. 285 (15), pp. 11537-11546
Xie, Heidi Qunhui; Liang, Dong; Leung, Ka Wing; Chen, Vicky Ping; Zhu, Kevin Yue; Chan, Wallace Kin Bon; Choi, Roy Chi Yan; Massoulié, Jean; Tsim, Karl Wah Keung Article
The expression of erythropoietin triggered by Danggui Buxue Tang, a Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells
Journal of Ethnopharmacology, v. 132, (1), October 2010, p. 259-267
Zheng, Ken Y Z; Choi, Chi Yan; Xie, Qunhui; Cheung, Wing Han; Guo, A.J.Y.; Leung, Ka Wing; Chen, Ping; Bi, Weichuan; Zhu, Kevin Y; Chan, Kar Lun Gallant; Fu, Qiang; Lau, David T W; Dong, Ting Xia; Zhao, K.J.; Tsim, Karl Wah Keung Article
The PRiMA-linked cholinesterase tetramers are assembled from homodimers hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain
Journal of biological chemistry, v. 285, (35), 2010, AUG 27, p. 27265-27278
Chen, Vicky Ping; Xie, Heidi Qunhui; Chan, Wallace Kin Bon; Leung, Ka Wing; Chan, Kar Lun Gallant; Choi, Roy Chi Yan; Bon, Suzanne; Massoulie, Jean; Tsim, Karl Wah Keung Article
黄芪中7种活性成分对缺氧诱导因子(HIF-1)表达的影响
中国药房=China Pharmacy, v. 2010, (47), 2010, p. 4422-4424
梁丽娟; 董婷霞; 詹华强; 屠鹏飞; 赵奎君 Article
"Female ginseng" – DANGGUI (当归): study on chemical profile after wine-processing
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Zhan, JYX; Zheng, KYZ; Bi, CWC; Zhu, KY; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
A new species of cholinesterase in chicken brain: PRiMA-linked AChE-BChE hybrid tetramer
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chen, VP; Chan, Kin Bon Wallace; Leung, Ka Wing; Zhang, VQ; Chan, GKL; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
A novel authentication method on edible bird nest by TripleQuad LC-MS/MS
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, XINJIANG CHINA, 2010
Chan, GKL; Li, J.; Wang, SH; Wang, TJ; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
A novel G-protein-coupled receptor complex: heterodimerization of purinergic P2Y1 and P2Y2 receptors
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chan, GKL; Leung, Ka Wing; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Acetylcholinesterase in erythrocytes: A non-cholinergic role in regulating erythropoiesis
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, 2010
Zhang, VQ; Chen, VP; Guo, AJY; Chan, GKL; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Aqueous extract of the root and rhizome of Rhodiola crenuclata induces the accumulation of HIF-1α via blocking the degradation pathway
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, , 2010
Zheng, KYZ; Guo, AJY; Bi, CWC; Zhu, KY; Xu, SL; Zhan, JYX; Chan, GKL; Cheung, Wing Han; Lau, David T W; Dong, Tina Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Authentication of dendrobium species by DNA sequencing method: clarification of the definition of Chinese pharmacopeia
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Chan, GKL; Jiang, ZW; Choi, Roy Chi Yan; Lau, David T W; Tsim, Karl Wah Keung Conference paper
Combination of baicalein and daidzein synergistically enhanced the estrogenic and neuroprotective effects: drug development against Alzheimer's disease
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Guo, AJY; Xu, SL; Zheng, KYZ; Cheung, Wing Han; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Estrogenic and neuroprotective effects of baicalein and daizein: drug development against Alzheimer's disease
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Guo, AJY; Cheung, Wing Han; Zhu, KY; Zheng, KYZ; Xu, SL; Lau, David T W; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Fo Shou San, an ancient herbal decoction prepared from Angelica Sinensis Radix and Chuangxiong Rhizoma, stimulates the production of hemoglobin and erythropoietin in cultured cells
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang China, 2010
Bi, CWC; Xie, HQ; Xu, SL; Li, Jun; Cheung, Wing Han; Zheng, KYZ; Lau, DTW; Choi, Chi Yan; Wang, TJ; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Investigation of KAI XIN SAN (开心散) and DING ZHI WAN (定志丸) – two traditional herbal formulae in treating mental disorder elucidation of action mechanism with chemical and biological methods
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, XINJIANG CHINA, 2010
Zhu, KY; Choi, Roy Chi Yan; Luk, WKW; Lau, David T W; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Neuroprotective and neurogenic effect of flavnoids derived from the traditional Chinese medicines
6th Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, HONG KONG, 2010
Xu, SL; Guo, AJY; Cheung, Wing Han; Zhu, KY; Zheng, KYZ; Lau, David T W; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Objectives, delivery and assessment – adoption of the outcome-based education triangular philosophy and methodologies at the program level of a biology program
TARC International Conference on Learning and Teaching TIC2010, Tunku Abdul Rahman College, Malaysia, 18-19, Oct, 2010
Yu, L.; Siow, NL; Tsim, Karl Wah Keung; Chow, King Lau Conference paper
Post-translational modification of PRiMA-linked G4 AChE by glycosylation
Joint Annual Scientific Meeting of the Hong Kong Society of Neurosciences and the Biophysical Society of Hong Kong, HONG KONG, 2010
Chan, Kin Bon Wallace; Chen, VP; Leung, Ka Wing; Zhang, VQ; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
Promoting students' personal development through biology co-curriculum in partnership with non-academic units
TARC International Conference on Learning and Teaching TIC2010, Tunku Abdul Rahman College, Malaysia. October 18-19, 2010
KO, IWP; Chow, King Lau; Ren, YY; Tsim, Karl Wah Keung Conference paper
Tandem mass spectrometric analysis of triterpene saponins in Weilingxian (Roots and Rhizomes of Clematis chinensis) by RRLC-DAD-ESI-MSn
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang China, 2010
Fu, Q.; Zan, K.; Zhao, MB; Zhou, SX; Shi, SP; Tu, PF; Tsim, Karl Wah Keung Conference paper
The optimization of wine-processing of Angelica Sinensis Radix via chemical assessment and GC-MS fingerprinting
2nd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang, China, 2010
Zhan, JYX; Zheng, KYZ; Bi, CWC; Zhu, KY; Fu, Q.; Duan, Ran; Lau, David T W; Dong, Ting Xia; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
2009 19
A new variant of proline-rich membrane anchor (PRiMA) of acetylcholinesterase in chicken: Expression in different muscle fiber types
Neuroscience Letters, v. 461, (2), 2009, SEP 11, p. 202-206
Mok, Mokka K.W.; Leung, Ka Wing; Xie, Heidi Qunhui; Guo, Ava Jiang Yang; Chen, Vicky Ping; Zhu, Judy Ting Ting; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Can Rhizoma Chuanxiong Replace Radix Angelica Sinensis in the Traditional Chinese Herbal Decoction Danggui Buxue Tang?
Planta medica, v. 75, (6), May 2009, p. 602-606
Li, W.Z.M.; Li, Jun; Bi, Wenchuan; Cheung, Anna Wing Hsn; Huang, Wen; Duan, Ran; Choi, Roy Chi Yan; Chen, Ivy S.Y.; Zhao, Kuijun; Dong, Ting Xia; Duan, Jin A.; Tsim, Karl Wah Keung Article
Cordysinocan, a Polysaccharide Isolated from Cultured Cordyceps, Activates Immune Responses in Cultured T-lymphocytes and Macrophages: Signaling Cascade and Induction of Cytokines
Journal of Ethnopharmacology, v. 124, (1), July 2009, p. 61-68
Cheung, Ka Hei; Li, Jun; Cheung, Wing Han; Zhu, Kevin Y; Zheng, Ken Y Z; Bi, Wenchuan; Duan, Ran; Choi, Chi Yan; Lau, David T W; Dong, Ting Xia; Lau, Brad W.C.; Tsim, Karl Wah Keung Article
Differential and Synergistic Effect of Nerve Growth Factor and cAMP on the Regulation of Early Response Genes during Neuronal Differentiation
NeuroSignals, v. 17, (2), May 2009, p. 111-120
Ng, Yu Pong; Wu, Zhenguo; Wise, Helen; Tsim, Karl Wah Keung; Wong, Yung Hou; Ip, Nancy Yuk-Yu Article
Effect of Extraction Solvent on the Bioactivity of an Herbal Formulation
Industrial and Engineering Chemistry Research, v. 48, (10), May 2009, p. 4852-4857
Chan, Kin N.; Lau, Choi C.; Chow, King Lau; Ko, Robert Kam Ming; Tsim, Karl Wah Keung; Ng, Ka Ming Article
Estrogenic and Neuroprotective Properties of Scutellarin from Erigeron breviscapus: A Drug against Postmenopausal Symptoms and Alzheimer's Disease
Planta medica, v. 75, (14), June 2009, p. 1489-1493
Zhu, Judy T T; Choi, Chi Yan; Li, Jun; Xie, Qunhui; Bi, Wenchuan; Cheung, Wing Han; Dong, Ting Xia; Jiang, Zhiyong; Chen, Jijun; Tsim, Karl Wah Keung Article
Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons
Neuroscience Letters, v. 461, (2), September 2009, p. 172-176
Zhu, Judy T T; Choi, Chi Yan; Xie, Qunhui; Zheng, Ken Y Z; Guo, A.J.Y.; Bi, Wenchuan; Lau, David T W; Li, Jun; Dong, Ting Xia; Lau, Brad W.C.; Chen, Ji J.; Tsim, Karl Wah Keung Article
HPLC法测定女贞子药材中女贞苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 29, (5), 2009, p. 824-826
黄雯; 苏子仁; 毕文川; 李军; 施丽琼; 文英强; 詹华强 Article
HPLC测定当归补血片中黄芪甲苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 29, (9), 2009, p. 1553-1555
刘玮锦; 蔡大可; 刘亮锋; 赖平; 董婷霞; 詹华强; 苏子仁 Article
Ligustilide Suppresses the Biological Properties of Danggui Buxue Tang: A Chinese Herbal Decoction Composed of Radix Astragali and Radix Angelica sinensis
Planta medica, v. 76, (5), October 2009, p. 439-443
Zheng, Ken Yu Zhong; Choi, Roy Chi Yan; Li, Jun; Xie, Heidi Qunhui; Cheung, Anna Wing Han; Duan, Ran; Guo, Ava Jiang Yang; Zhu, Judy Ting Ting; Chen, Vicky Ping; Bi, Wenchuan; Zhu, Kevin Yue; Lau, David Tai Wai; Dong, Tina Ting Xia; Lau, Brad Wing Chuen; Tsim, Karl Wah Keung Article
Quality Evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by Using High-performance Liquid Chromatography Coupled with Diode Array Detector and Mass Spectrometry
Journal of Chromatography A, v. 1216, (11), March 2009, p. 2071-2078
Li, Jun; Li, Winnie Z.M.; Huang, Wen; Cheung, Wing Han; Bi, Wenchuan; Duan, Ran; Guo, A.J.Y.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Restricted localization of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase at the neuromuscular junctions - contribution and expression from motor neurons
FEBS JOURNAL, v. 276, (11), 2009, JUN, p. 3031-3042
Leung, Ka Wing; Xie, Heidi Qunhui; Chen, Vicky Ping; Mok, Mokka K.W.; Chu, Glanice K.Y.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines
Chinese Medicine, v. 4, 2009
Guo, Ava Jiang Yang; Choi, Roy Chi-Yan; Cheung, Anna Wing Han; Li, Jun; Chen, Ivy X.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Lau, B.W.C. Article
Transcriptional regulation of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in neuron: An inductive effect of neuron differentiation
Brain research, v. 1265, 2009, APR 10, p. 13-23
Xie, Heidi Qunhui; Choi, Roy Chi Yan; Leung, Ka Wing; Chen, Vicky Ping; Chu, Glanice K.Y.; Tsim, Karl Wah Keung Article
Two new compounds from the roots of Ligusticum chuanxiong
Journal of Asian natural products research, v. 11, (9), 2009, p. 805-810
Chang, Xin-Liang; Jiang, Zhi-Yong; Ma, Yun-Bao; Zhang, Xue-Mei; Tsim, Karl Wah Keung; Chen, Ji-Jun Article
A novel non-cholinergic function of acetylcholinesterase: osteogenic effect in cultured osteocarcoma MG-63 cells
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Sociey of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Guo, A.J.Y.; Zhu, Judy T T; Zheng, Ken Y Z; Bi, Wenchuan; Xie, Qunhui; Tsim, Karl Wah Keung Conference paper
Identification and characterization of splice variants of Proline Rich Membrane Anchor (PRiMA) of acetylcholinesterase (AChE) in different muscle fiber types in chicken
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Society of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Mok, Ka Wai; Chen, Ping; Chu, Kin Yan; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Quality control of ginseng by 1H NMR metabolic profiling
International Conference on Resource Development of Chinese Medicines from Northwestern China, Hong Kong, China, 2009
Chan, Pui Hei Nicholas; Choi, Chi Yan; Chan, Kar Lun Gallant; Tsim, Karl Wah Keung; Lam, Henry H N Conference paper
The molecular assembly of acetylcholinesterase and butyrylcholinesterase: the formation of PRiMA-linked G4 hybrid
The 6th Asian Biophysics Association (ABA) Symposium organized by the Biophysical Society of Hong Kong and the Hong Kong Society of Neurosciences, Hong Kong, 11-15 Jan 2009
Chen, Ping; Xie, Qunhui; Leung, Ka Wing; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
2008 15
A chinese herbal decoction prepared from radix astragali and radix angelicae sinensis induces the expression of erythropoietin in cultured Hep3B cells
Planta medica, v. 74, (4), 2008, MAR, p. 392-395
Gao, Qiu T.; Cheung, Jerry K.H.; Choi, Roy Chi Yan; Cheung, Anna Wing Han; Lv, Jun; Jiang, Zhi Y.; Duan, Ran; Zhao, Kui J.; Ding, An W.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Constitutive and agonist-induced dimerizations of the P2Y(1) receptor - Relationship to internalization and scaffolding
Journal of biological chemistry, v. 283, (16), 2008, APR 18, p. 11050-11063
Choi, Roy Chi Yan; Simon, Joseph; Tsim, Karl Wah Keung; Barnard, Eric A. Article
Myocyte enhancer factor 2 mediates acetylcholine-induced expression of acetylcholinesterase-associated collagen ColQ in cultured myotubes
MOLECULAR AND CELLULAR NEUROSCIENCE, v. 39, (3), October 2008, p. 429-438
Lau, Faye T.C.; Choi, Chi Yan; Xie, Qunhui; Leung, Ka Wing; Chen, Ping; Zhu, Judy T T; Bi, Weichuan; Chu, Glanice K.Y.; Tsim, Karl Wah Keung Article
Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity
Biochemical and biophysical research communications, v. 366, (3), 2008, FEB 15, p. 631-636
Fu, Hongjun; Li, Wenming; Luo, Jialie; Lee, Nelson T.K.; Li, Mingtao; Tsim, Karl Wah Keung; Pang, Yuanping; Youdim, Moussa B.H.; Han, Yifan Article
Regulation of PRiMA-linked G(4) AChE by a cAMP-dependent signaling pathway in cultured rat pheochromocyoma PC12 cells
Chemico-biological interactions, v. 175, (1-3, Sp. Iss. SI), 2008, SEP 25, p. 76-78
Choi, Roy Chi Yan; Mok, Mokka K.W.; Cheung, Anna Wing Han; Siow, Nina Lam; Xie, Heidi Qunhui; Tsim, Karl Wah Keung Article
Special Issue: Proceedings of the IXth International Meeting on Cholinesterases Preface
Chemico-biological interactions, v. 175, September 2008, p. 1-2
Doctor, Bhupendra P.; Tsim, Karl Wah Keung; Siow, Nina L. Article
The promoter activity of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in muscle: Suppressive roles of myogenesis and innervating nerve
Chemico-biological interactions, v. 175, (1-3, Sp. Iss. SI), 2008, SEP 25, p. 79-82
Xie, Heidi Qunhui; Leung, Ka Wing; Chen, Vicky Ping; Lau, Faye T.C.; Liu, Lois S.; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Transcriptional Control of Different Subunits of AChE in Muscles: Signals Triggered by the Motor Nerve-derived Factors
Chemico-biological interactions, v. 175, (1-3), September 2008, p. 58-63
Tsim, Karl Wah Keung; Choi, Chi Yan; Xie, Qunhui; Zhu, Judy T T; Leung, Ka Wing; Lau, Faye T.C.; Chu, Glanice K.Y.; Chen, Ping; Mok, Mokka K.W.; Cheung, Wing Han; Bi, Weichuan Article
Anti-obesity effect of tectorigenin isolated from rhizoma belamcandae: regulation on apolipoprotein A-IV promoter in Caco2/TC7 enterocytes
The 3rd International Symposium on Functional Foods 2008 - Health Benefits of Plant Polyphenols, organized by PolyU, Hong Kong, 5 April 2008
Guo, Ava Jiangyang; Choi, Chi Yan; Li, Jun; Duan, Ran; Li, Winnie Z.M.; Cheung, J.K.H.; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung Conference paper
Development of new Chinese herbal decoction for anti-obesity
2008 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, Hong Kong, 15 August 2008
Guo, Jiangyang; Huang, Wen; Duan, Ran; Li, Jun; Choi, Chi Yan; Dong, Tingxia; Lau, Brad W.C.; Tsim, Karl Wah Keung Conference paper
Localization of Proline-Rich Membrane Anchor (PRiMA)-associated acetylcholinesterase in vertebrate neuromuscular junctions
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, August 16-20, 2008, P17
Leung, Ka Wing; Xie, Qunhui; Bi, Wenchuan; Cheung, Ka Hei; Mok, Ka Wai; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Osteogenic effect of PRiMA-linked acetylcholinesterase in cultured MG-63 osteocarcoma cells
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, 16-20, August, 2008
Choi, Chi Yan; Zhu, Tingting; Xie, Qunhui; Chu, Kin Yan; Lau, Faye; Chen, Ping; Lin, Huangquan; Wan, David C.C.; Tsim, Karl Wah Keung Conference paper
Regulation of PRiMA-linked acetylcholinesterase in muscles, neurons and osteoblasts
The XIIIth International Symposium on Cholinergic Mechanisms 'Neuronal and Non-Neuronal Cholinergic Systems: Molecular and Translational Significance', Foz do Iguacu, Brazil, 16-20 August, 2008
Tsim, Karl Wah Keung; Xie, Qunhui; Leung, Ka Wing; Zhu, Tingting; Chu, Kin Yan; Chen, Ping; Guo, Jiangyang; Choi, Chi Yan Conference paper
Studies on Dangui Buxue Tang: and example of Chinese herbal decoction flavonoids originated from Chinese Materia Medica (CMM): protect neurons against oxidative stress and beta-amyloid-induced cytotoxicity
2008 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six local universities, Hong Kong, 15 August 2008
Zhu, Tingting; Choi, Chi Yan; Cheung, Wing Han; Gao, Qiutao; Li, Jun; Dong, Tingxia; Tsim, Karl Wah Keung Conference paper
Synergistic action of baicalein and daidzein in estrogenic and neuroprotective effects: development of potential health products and therapeutic drugs against alzheimer's disease
The 3rd International Symposium on Functional Foods 2008 - Health Benefits of Plant Polyphenols, organized by PolyU, Hong Kong, 5 April 2008
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Li, Jun; Li, Winnie Z.M.; Duan, Ran; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
2007 34
Calcitonin gene-related peptide induces the expression of acetylcholinesterase-associated collagen ColQ in muscle: a distinction in driving two different promoters between fast- and slow-twitch muscle fibers
Journal of neurochemistry, v. 102, (4), 2007, AUG, p. 1316-1328
Choi, Roy Chi Yan; Ting, Annie K.L.; Lau, Faye T.C.; Xie, Heidi Quihui; Leung, Ka Wing; Chen, Vicky Ping; Siow, Nina Lam; Tsim, Karl Wah Keung Article
Cloning and characterization of the yjeA gene, encoding a novel deoxyribonuclease, from Bacillus subtilis
Journal of Biochemistry, v. 142, (5), 2007, Nov, p. 647-654
Ng, Ka Lun; Lam, Chui Chi; Fu, Zhibiao; Han, Yi-Fan; Tsim, Karl Wah Keung; Wong, Wan Keung Article
Danggui Buxue Tang - A Chinese herbal decoction activates the phosphorylations of extracellular signal-regulated kinase and estrogen receptor alpha in cultured MCF-7 cells
FEBS letters, v. 581, (2), 2007, JAN 23, p. 233-240
Gao, Qiu T.; Choi, Roy Chi Yan; Cheung, Anna Wing Han; Zhu, Judy Ting Ting; Li, Jun; Chu, Glanice K.Y.; Duan, Ran; Cheung, Jerry K.H.; Jiang, Zhi Y.; Dong, Xiao B.; Zhao, Kui J.; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Dang-Gui Buxue Tang protects against oxidant injury by enhancing cellular glutathione in H9c2 cells: Role of glutathione synthesis and regeneration
Planta medica, v. 73, (2), 2007, FEB, p. 134-141
Chiu, Po Yee; Leung, Hoi Yan; Siu, Ada H.Y.; Poon, Michel K.T.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Ko, Kam Ming Article
Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: A comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death
Journal of agricultural and food chemistry, v. 55, (6), 2007, MAR 21, p. 2438-2445
Zhu, Judy Ting Ting; Choi, Roy Chi Yan; Chu, Glanice K.Y.; Cheung, Wing Han; Gao, Qiu T.; Li, Jun; Jiang, Zhi Y.; Dong, Ting Xia; Tsim, Karl Wah Keung Article
HPLC法测定远志中总皂苷的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2007, (09), 2007, p. 1329-1332
李军; 董晓兵; 姜勇; 董婷霞; 屠鹏飞; 詹华强 Article
Identification and quality control of Radix et Rhizoma Gentianae by chemical fingerprint: evaluation of gentiopicrin from different cultivated regions in China
Asian Journal of the Traditional Medicines, v. 1, (3-4), p. 1-9
Gao, Q.T.; Chou, G.X.; Dong, Tina Tingxia; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Tsim, Karl Wah Keung Article
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons
Journal of proteome research, v. 6, (7), 2007, p. 2435-2446
Fu, Hongjun; Li, Wenming; Liu, Yulin; Lao, Yuanzhi; Liu, Wei; Chen, Cheng; Yu, Hua; Lee, Nelson T.K.; Chang, Donald C.; Li, Peng; Pang, Yuanping; Tsim, Karl Wah Keung; Li, Mingtao; Han, Yifan Article
Regions in China identification and quality control of radix Codonopsis by chemical fingerprint: Evaluation of lobetyolin from different cultivated
Oriental Pharmacy and Experimental Medicine, v. 6, (4), 2006, p. 293-299
Chou, Gui X.; Gao, Qiu T.; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Chu, Glanice K.Y.; Jiang, Zhi Y.; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Regulation of a transcript encoding the proline-rich membrane anchor of globular muscle acetylcholinesterase - The suppressive roles of myogenesis and innervating nerves
Journal of biological chemistry, v. 282, (16), 2007, APR 20, p. 11765-11775
Xie, Heidi Qunhui; Choi, Roy Chi Yan; Leung, Ka Wing; Siow, Nina Lam; Kong, Ling W.; Lau, Faye T.C.; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung Article
Regulation of acetylcholinesterase expression by calcium signaling during calcium ionophore A23187-and thapsigargin-induced apoptosis
International journal of biochemistry & cell biology, v. 39, (1), 2007, p. 93-108
Zhu, Hui; Gao, Wei; Jiang, Hua; Jin, Qi-Huang; Shi, Yu-Fang; Tsim, Karl Wah Keung; Zhang, Xue-Jun Article
Simultaneous determination of phenols in Radix Polygalae by high performance liquid chromatography: Quality assurance of herbs from different regions and seasons
Journal of separation science, v. 30, (16), 2007, NOV, p. 2583-2589
Li, Jun; Dong, Xiaobing; Jiang, Yong; Gao, Qiutao; Jiang, Zhiyong; Cheung, Anna Wing Han; Duan, Ran; Dong, Tina Tingxia; Tu, Pengfei; Tsim, Karl Wah Keung Article
Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase
Molecular pharmacology, v. 71, (5), 2007, May, p. 1258-1267
Li, Wenming; Xue, Jian; Niu, Chunying; Fu, Hongjun; Lam, Colin S.C.; Luo, Jialie; Chan, Hugh H.N.; Xue, Huaiguo; Kan, Kelvin K.W.; Lee, Nelson Tsz Kin; Li, Chaoying; Pang, Yuanping; Li, Mingtao; Tsim, Karl Wah Keung; Jiang, Hualiang; Chen, Kaixian; Li, Xiaoyuan; Han, Yifan Article
Verification of the formulation and efficacy of Danggui Buxue Tang (a decoction of Radix Astragali and Radix Angelicae Sinensis): An exemplifying systematic approach to revealing the complexity of Chinese herbal medicine formulae
Chinese Medicine, v. 2, 2007
Gao, Qiutao; Li, Jun; Cheung, J.K.H.; Duan, Jinao; Ding, Anwei; Cheung, Anna Wing Han; Zhao, Kuijun; Li, Winnie Zhouming; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
测定天王补心丸和归脾丸中细叶远志皂苷的含量
中国中药杂志=China Journal of Chinese Materia Medica, v. 2007, (16), 2007, p. 1647-1649
董晓兵; 李军; 姜勇; 董婷霞; 屠鹏飞; 詹华强 Article
远志皂苷对照品细叶远志皂苷的制备
中药新药与临床药理=Traditional Chinese Drug Research and Clinical Plarmacology, v. 2007, (01), 2007, p. 53-54
董晓兵; 李军; 郑颖; 董婷霞; 詹华强 Article
A Chinese herbal decoction stimulates the expression of apolipoprotein A-IV in cultured enterocytes Caco 2 – TC7 cells: a possible drug for anti-obesity
2007 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six local universities, Hong Kong, 16 August 2007
Guo, A.J.Y.; Cheung, J.K.H.; Li, J.; Duan, Ran; Choi, Chi Yan; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung Conference paper
A Chinese Herbal decoction, Danggui Buxue Tang (DBT), stimulates the release of cytokines in cultured T-lymphocytes: A signal triggered by extracellular signal-regulated kinase
2007 Hong Kong - Macau Postgraduate Symposium on Chinese Medicine, organized by Modernized Chinese Medicine International Association and six loca universities, Hong Kong, 16 August 2007
Cheung, J.K.H.; Gao, Q.T.; Li, J.; Jiang, Z.Y.; Chu, G.K.Y.; Duan, Ran; Cheung, Wing Han; Zhao, K.J.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
A chinese herbal decoction, danggui buxue tang, activates extracellular signal-regulated kinase in cultured T-lymphocytes
FEBS letters, v. 581, (26), 2007, OCT 30, p. 5087-5093
Gao, Qiu T.; Cheung, Jerry K.H.; Li, Jun; Jiang, Zhi Y.; Chu, Glanice K.Y.; Duan, Ran; Cheung, Anna Wing Han; Zhao, Kul J.; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Conference paper
Anti-obesity effect of a Chinese herbal decoction: Regulation of apolipoprotein A-IV expression and triglyceride formation
2007 TWGHs Eddie Wang Symposium on Integrated Chinese & Western Medicine, organized by Tung Wah Group of Hospitals & Hospital Authority, Hong Kong, 2 November 2007
Guo, A.J.Y.; Cheung, J.K.H.; Li, J.; Duan, Ran; Choi, Chi Yan; Dong, Ting Xia; Lau, B.W.C.; Tsim, Karl Wah Keung Conference paper
ATP induces acetylcholinesterase gene expression in cortical neurons: transduction and transcription control via P2Y1 receptors
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Siow, Nina Lam; Choi, Roy Chi Yan; Xie, Heidi Qunhui; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
Characterization of proline-rich membrane anchor (PRiMA)-associated acetylcholinesterase in cholinergic synapses
The IXth International Meeting on Cholinesterases, Suzhou, China
Leung, Ka Wing; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Cloning and characterization of acetylcholinesterase of green pufferfish tetraodon nigroviridis
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Lau, L.S.; Tung, E.; Lin, H.Q.; Tsim, Karl Wah Keung; Wan, D.C. Conference paper
Flavonoids derived from traditional Chinese medicine (TCM) in regulating the transcription of Acetylcholinesterase in osteosarcoma MG63 cells
2007 Hong Kong - Macau postgraduate symposium on Chinese medicine, Hong Kong,16 August 2007
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Xie, Qunhui; Ho, C.L.T.; Tsim, Karl Wah Keung Conference paper
Flavonoids derived from traditional chinese medicine (TCM) regulate the transcription of acetylcholinesterase in osteosarcoma MG63 cells
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Zhu, J.T.; Choi, Chi Yan; Cheung, Wing Han; Xie, Qunhui; Ho, C.L.T.; Tsim, Karl Wah Keung Conference paper
Flavonoids possess neuroprotective effects by preventing beta-amyloid-induced cell death on cultured neurons
2007 TWGHs Eddie Wang Symposium on Integrated Chinese & Western Medicine, organized by Tung Wah Group of Hospitals & Hospital Authority, Hong Kong, 2 November 2007
Zhu, J.T.; Chu, G.K.Y.; Dong, Ting Xia; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Li, W.; Fu, H.; Liu, Y.L.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Y. Conference paper
Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity
The IXth International Meeting on Cholinesterases, Suzhou, China
Fu, H.; Li, Wenming; Pi, R.B.; Luo, J.L.; Pang, Y.P.; Tsim, Karl Wah Keung; Han, Y. Conference paper
Regulation of a transcript encoding the proline-rich membrane anchor of globular muscle acetylcholinesterase: The suppressive roles of myogenesis and innervating nerves
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Leung, Ka Wing; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Regulation of different subunits of acetylcholinesterase expression during the nerve growth factor-induced neuronal differentiation in cultured PC12 cells
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Choi, Chi Yan; Mok, M.K.W.; Leung, Ka Wing; Siow, Lam; Tsim, Karl Wah Keung Conference paper
Stimulation of collagen-like subunit (ColQ) of acetylcholinesterase by muscular activity in muscle
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Lau, F.T.C.; Chen, Ping; Yim, J.C.H.; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
The expression of P2Y2, P2Y4 and P2Y6 receptors in cultured cortical neurons: signaling leads to acetylcholinesterases expression
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Chu, G.K.Y.; Siow, Lam; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
The motor nerve directs the oligomerization of collagen-tailed form acetylcholinesterase in muscles
The IXth International Meeting on Cholinesterases, Suzhou, China
Chen, Ping; Xie, Qunhui; Lau, F.T.C.; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Transcriptional control of different subunits of AChE in muscle: a regulation mediated by CAMP-dependent signaling cascades
The IXth International Meeting on Cholinesterases, organized by HKUST & Shanghai Institute of Materia Medica, Suzhou, China
Tsim, Karl Wah Keung Conference paper
2006 48
A Chinese herbal decoction, Danggui Buxue Tang, prepared from Radix Astragali and Radix Angelicae Sinensis stimulates the immune responses
Planta Medica, v. 72, (13), 2006, Oct, p.1227-1231
Gao, Qiutao; Cheung, J.K.H.; Li, Jun; Chu, Glanice K.Y.; Duan, Ran; Cheung, Anna Wing Han; Zhao, Kuijun; Dong, T.T.X.; Tsim, Karl Wah Keung Article
A fructan, from radix ophiopogonis, stimulates the proliferation of cultured lymphocytes: Structural and functional analyses
Journal of natural products, v. 69, (9), 2006, SEP 22, p. 1257-1260
Wu, Xiangmei; Dai, Hui; Huang, Lixin; Gao, Xiaoming; Tsim, Karl Wah Keung; Tu, Pengfei Article
Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels
Journal of neurochemistry, v. 98, (5), 2006, SEP, p. 1400-1410
Fu, Hongjun; Li, Wenming; Lao, Yuanzhi; Luo, Jialie; Lee, Nelson T.K.; Kan, Kelvin K.W.; Tsang, Hing Wai; Tsim, Karl Wah Keung; Pang, Yuanping; Li, Zhiwang; Chang, Donald C.; Li, Mingtao; Han, Yifan Article
Chemical and biological assessment of a chinese herbal decoction containing radix astragali and radix angelicae sinensis: Determination of drug ratio in having optimized properties
Journal of agricultural and food chemistry, v. 54, (7), 2006, APR 5, p. 2767-2774
Dong, Tina Tingxia; Zhao, Kuijun; Gao, Qiutao; Ji, Zhaoning; Zhu, Ting T.; Li, Jun; Duan, Ran; Cheung, Anna Wing Han; Tsim, Karl Wah Keung Article
Chick acetylcholinesterase promoter regulation
Journal of molecular neuroscience, v. 30, (1-2), 2006, p. 33-34
Wan, David Chi Cheong; Zhang, Xiang; Siow, Nina L.; Xie, Heidi Qun Hui; Tsim, Karl Wah Keung Article
Dang-Gui Buxue Tang produces a more potent cardioprotective effect than its component herb extracts and enhances glutathione status in rat heart mitochondria and erythrocytes
Phytotherapy research, v. 20, (7), 2006, JUL, p. 561-567
Mak, Duncan Hon Fai; Chiu, Po Yee; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Ko, Kam Ming Article
Ginsenoside Re attenuate beta-amyloid and serum-free induced neurotoxicity in PC12 cells
Journal of ethnopharmacology, v. 107, (1), 2006, AUG 11, p. 48-52
Ji, Z.N.; Dong, Tina Ting Xia; Ye, W.C.; Choi, Roy Chi Yan; Lo, Chun Kit; Tsim, Karl Wah Keung Article
HPLC-ELSD Determination of Platycodin E in Radix Platcodonis of Different Sources
Chinese Journal of Pharmaceutical Analysis, 2006
Xia, Q.; Dong, Ting Xia; Tsim, Karl Wah Keung; Huang, Z.; Zhang, P. Article
HPLCELSD法测定不同来源桔梗中桔梗皂苷E的含量
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2006, (05), 2006, p. 637-639
夏泉; 董婷霞; 詹华强; 黄赵刚; 张平 Article
Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia
Phytomedicine, v. 13, (6), 2006, Jun, p. 428-433
Li, Shaoping; Zhang, Guihong; Zeng, Qingshu; Huang, Zhaogang; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
ICP-MS法测定4种中药材中重金属含量
高等学校化学学报=China Journal of Chinese Materia Medica, v. 2007, (16）, 2007, p. 1314-1317
温慧敏; 陈晓辉; 董婷霞; 詹华强; 毕开顺 Article
In vitro estrogenic activity of formononetin by two bioassay systems
Gynecological endocrinology, v. 22, (10), 2006, OCT, p. 578-584
Ji, Zhao-Ning; Zhao, W.Y.; Liao, G.R.; Choi, Roy Chi Yan; Lo, Chun Keung; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine
NeuroReport, v. 17, (5), 2006, April, p. 471-474
Li, Wenming; Lee, Nelson Tsz Kin; Fu, Hongjun; Kan, Kelvin K.W.; Pang, Yuanping; Li, Mingtao; Tsim, Karl Wah Keung; Li, Xiaoyuan; Han, Yifan Article
Quality control of Cordyceps sinensis, a valued traditional Chinese medicine
Journal of pharmaceutical and biomedical analysis, v. 41, (5), 2006, Aug, p. 1571-1584
Li, Shaoping; Yang, Fengqing; Tsim, Karl Wah Keung Article
Simultaneous determination of 11 saponins in Panax notoginseng using HPLC-ELSD and pressurized liquid extraction
Journal of separation science, v. 29, (14), 2006, SEP, p. 2190-2196
Wan, Jian-Bo; Li, Peng; Li, Shaoping; Wang, Yitao; Dong, Tina Ting-Xia; Tsim, Karl Wah Keung Article
Transcriptional control of different acetylcholinesterase subunits in formation and maintenance of vertebrate neuromuscular junctions
Journal of molecular neuroscience, v. 30, (1-2), 2006, p. 189-192
Tsim, Karl Wah Keung; Xie, Heidi Qun Hui; Ting, Annie; Siow, Nina L.; Ling, Karen K.Y.; Kong, Lingwei Article
固相萃取-毛细管气相色谱法测定党参、龙胆中15种有机氯农药的残留量
沈阳药科大学学报=Journal of Shenyang Pharmaceutical University, v. 2006, (12), 2006, p. 776-781
张潇潇; 陈晓辉; 董婷霞; 詹华强; 王晓东; 毕开顺 Article
莪术二酮对ADP诱导的兔血小板聚集的抑制作用
中国药理学通报=Chinese Pharmacological Bulletin, v. 2006, (09), 2006, p. 1151-1152
夏泉; 董婷霞; 詹华强; 梁嘉荣; 李绍平 Article
从西方思维看中药现代化
从西方思维看中药现代化 = Modernization of traditional Chinese medicine: a prospect from Western medicine / 孔宪铎, 詹华强着. 香港: 三联书店(香港)有限公司, 2006
Kung, Shain-Dow; Tsim, Karl Wah Keung Book
Quality Control of Cordyceps Sinensis, a Valued Traditional Chinese Medicine
/ Edited by J.N. Govil, V.K. Singh. Houston, Tex.: Studium Press LLC
Li, S.P.; Tsim, Karl Wah Keung Book chapter
A Chinese herbal decoction, Danggui Buxue Tang, prepared from Radix Astragali and Radix Angelicae Sinensis stimulates the immune responses
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Gao, Q.T.; Cheung, J.K.H.; Cheung, Wing Han; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Activation of P2Y1 receptor induces NR2A expression in cultured cortical neurons
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December , 2006
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
ATP Induces Post-Synaptic Specializations in Synapses: Transduction and Transcription control
Croucher Advanced Study Institution (ASI): Signaling in Cell Growth and Deifferentitaion, 16-20 Jan, 2006
Tsim, Karl Wah Keung Conference paper
Cordysinocan, a novel polysaccharide isolated from Cordyceps sinensis, stimulates the immune responses
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Cheung, J.K.H.; Cheung, Wing Han; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 Nanjing International Forum on Traditional Chinese Medicine, organized by Nanjing university of traditional chinese medicine and Administration of TCM of Jiangsu province, Nanjing, 4-6 November, 2006
Tsim, Karl Wah Keung Conference paper
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Tsim, Karl Wah Keung Conference paper
Danggui Buxue Tang (A Chinese Angelica Decoction): A sample trial in traditional Chinese medicine standardization
2006 Shanghai Forum on International Standardization of Chinese Medicines and Herbal Products, organized by Shanghai University of Traditional Chinese Medicine and Shanghai R&D Center for Standardization of Chinese Medicine, Shanghai, 10 December, 2006
Tsim, Karl Wah Keung Conference paper
Determination of Tectoridin as Irisflorentin in Rhizoma Belamcandae
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Li, J.; Dong, X.B.; Gao, Q.T.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Fractionation of Anti-platelet Aggregation Activity From Roots of Panax notoginsen
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Jiang, Z.Y.; Li, S.P.; Duan, Ran; Chen, J.J.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Identification and characterization of flavonoids from traditional Chinese medicines-drug discovery for neruoprotection
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Zhu, J.T.T.; Chu, G.K.Y.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Identification and characterization of flavonoids from traditional Chinese medicines-Drug discovery for neuroprotection
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Zhu, Judy T T; Chu, G.K.Y.; Cheung, Wing Han; Choi, Chi Yan; Dong, Ting Xia; Li, J.; Gao, Q.T.; Jiang, Z.Y.; Tsim, Karl Wah Keung Conference paper
Identification and characterization of interacting partners of PRiMA, a membrane anchor of acetylcholinesterase-A proteomic approach
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Leung, Ka Wing; Xie, Qunhui; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Immuno-stimulating study on polysaccharide isolated from cultured Cordyceps
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Cheung, J.K.H.; Li, S.P.; Li, J.; Tsim, Karl Wah Keung Conference paper
Isolation of active compound responsible for the anti-platelet aggregation from Radix Notoginseng
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Jiang, Z.Y.; Duan, Ran; Chen, J.J.; Leung, D.H.F.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Probing the effects of Chinese Medicine Materials (CMM) in stimulating the apolipoprotein A-IV (Apo A-IV) expression in cultured enterocytes Caco-2 / TC7 cells
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Duan, R.R.; Chan, E.Y.Y.; Li, J.; Raymond, M.P.; Lau, B.W.C.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Quantitative Proteomic Analysis of the Neuroprotection of Bis(7)-Tacrine Against Glutamate-Induced Mitochondrial Dysfunction
36th Annual Meeting of the Society for Neuroscience, Georgia World Congress Center, Atlanta, Georgia (USA), 14-18 Oct 2006
Fu, H.; Li, W.; Liu, Y.; Lao, Y.; Lee, N.T.; Liu, W.; Li, K.C.; Pang, Y.; Chang, Donald C; Tsim, Karl Wah Keung; Li, M.; Han, Y. Conference paper
Radix Polygala protects PC12 cells from amyloid-beta peptide-induced neurotoxicity
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Li, J.; Chu, G.K.Y.; Dong, X.B.; Choi, Chi Yan; Lau, B.W.C.; Wong, Z.C.F.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Radix Polygala Protects PC12 Cells from Amyloid-Peptide-Induced Neurotoxicity
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Li, J.; Chu, G.K.Y.; Dong, X.B.; Choi, Chi Yan; Lau, B.W.C.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Regulation of acetylcholinesterase in neuron: The role of PRiMA in directing the formation of G4 AChE
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Choi, Chi Yan; Siow, Lam; Xie, Qunhui; Tsim, Karl Wah Keung Conference paper
Regulation of Collagen-like subunit (ColQ) of acetylcholinesterase by muscular activity in muscles
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Lau, F.T.C.; Chen, Ping; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Regulation of Transcript Encoding Proline-rich Membrane Anchor (PRiMA) of Globular form Acetylcholinesterase in Muscle: Suppressive Role of Myogenesis and Innervating Nerve
The 4th Congress of Federation of Asian and Oceanian Neuroscience Societies (FAONS), Hong Kong. 30 November - 2 December, 2006
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Leung, Ka Wing; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Specific estrogenic and immune regulatory effects of Danggui Buxue Tang-a traditional Chinaese herbal decoction prepared from Radix Angelicae Sinensis and Radix Astragali
2006 Hong Kong-Macau Postgraduate Symposium on Chinese Medicine, Organised by Modernized Chinese Medicine International Association, six universities in Hong Kong and University of Macau, Hong Kong, 17 August , 2006
Gao, Q.T.; Cheung, J.K.H.; Cheung, Wing Han; Jiang, Z.Y.; Li, J.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Synergistic Neuroprotection by BIS(7)-Tacrine Via Moderate Blockade of N-Methyl-D-Aspartate Receptors and Selective Inhibition of Neuronal Nitric Oxide Synthase
36th Annual Meeting of the Society for Neuroscience, Georgia World Congress Center, Atlanta, Georgia (USA), 14-18 Oct 2006
Li, W.; Xue, J.; Niu, C.; Fu, H.; Lam, C.S.; Lee, N.T.; Pang, Y.; Li, M.; Jiang, H.; Chen, K.; Tsim, Karl Wah Keung; Li, X.; Han, Y. Conference paper
The Effects of Zhikang Granules in stimulating the Apolipoprotein A-IV (Apo A-IV) Expression in Cultured Enterocytes Caco-2 / TC7 cells
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Dong, Ting Xia; Duan, Ran; Chan, E.Y.Y.; Li, J.; Tsim, Karl Wah Keung Conference paper
The expression and functional role of P2Y2, P2Y4 and P2Y6 receptors in cultured cortical neurons
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Chu, G.K.Y.; Siow, Lam; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
The motor nerve directs the oligomerization of collagen-tailed form acetylcholinesterase in muscles
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), organized by FAONS, Hong Kong, 30 November - 2 December, 2006
Chen, Ping; Xie, Qunhui; Lau, F.T.C.; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
The Preparation of Tenuifolin as Chemical Market of Radix Polygalae
2006 The two sides of Taiwan Straits / The 7th National Symposium on Natural Medicinal Material Resources CSNR (Proceedings and Abstracts), organized by China Society of Natural Resources and Hubei College of Traditional Chinese medicine, Wuhan, 21-24 September, 2006
Dong, X.B.; Li, J.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
Traditional Chinese medicines reduce triglyceride accumulation in cultured adipocyte (3T3-L1 cells)
2006 World Congress on Chinese Medicine: Charting the Course of Development, organized by Hong Kong Baptist University, Hong Kong, 23-25 November, 2006
Guo, A.J.Y.; Chu, G.K.Y.; Ho, C.L.T.; Choi, Chi Yan; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
2005 37
A DNA microarray for the authentication of toxic traditional Chinese medicinal plants
Planta Medica, v. 71, (6), June 2005, p. 580-584
Carles, Maria C.; Cheung, Kin Lok; Moganti, Shanti; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu; Sucher, Nikolaus J. Article
An arabinogalactan isolated from the stems of Cistanche deserticola induces the proliferation of cultured lymphocytes
International journal of biological macromolecules, v. 37, (5), 2005, Dec, p. 278-282
Wu, Xiangmei; Gao, Xiaoming; Tsim, Karl Wah Keung; Tu, Pengfei Article
ATP induces the post-synaptic gene expression in neuron-neuron synapses: Transcriptional regulation of AChE catalytic subunit
Chemico-biological interactions, December 15, 2005, 157-158:423-426
Siow, Nina L.; Xie, Heidi Q.; Choi, Roy C.Y.; Tsim, Karl Wah Keung Article
ATP potentiates the formation of AChR aggregate in the co-culture of NG108-15 cells with C2C12 myotubes
FEBS letters, v. 579, (11), 2005, APR 25, p. 2469-2474
Ling, KKY; Siow, Nina Lam; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Article
Authentication and quality control of Cordyceps sinensis, a traditional Chinese medicine known as summer-grass winter-worm
Oriental Pharmacy and Experimental Medicine, v.5, (4), p.262-271
Cheung, Jerry K.H.; Li, Shaoping; Tsim, Karl Wah Keung Article
Danggui Buxue Tang (Chinese Angelica Decoction): A Sample Trial in TCM Standardization
Asia-Pacific Biotech News (APBN), v. 8, (23), 2004, Dec, p. 1316-1321
Tsim, Karl Wah Keung Article
Identificaiton of Stellaria medica by PCR
Journal of Chinese Pharmaceutical Sciences, v. 14, (3), 2005, p. 144-148
Huang, Wenzhe; Dong, Tina Tingxia; Qi, Huanyang; Lu, Zhenqiang; Tsim, Karl Wah Keung Article
Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry
Journal of pharmaceutical and biomedical analysis, v. 39, (3-4), 2005, SEP 15, p. 552-558
Yang, Fengqing; Li, Shaoping; Chen, Ying; Lao, Sincheng; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Molecular Genetic and Chemical Assessment of Rhizoma Curcumae in China
Journal of agricultural and food chemistry, v. 53, (15), 2005, Jul, p. 6019-6026
Xia, Quan; Zhao, Kuijun; Huang, Zhaogang; Zhang, Ping; Dong, Ting Xia; Li, Shaoping; Tsim, Karl Wah Keung Article
Novel dimeric acetylcholinesterase inhibitor bis(7)-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors
Journal of biological chemistry, v. 280, (18), 2005, MAY 6, p. 18179-18188
Li, Wenming; Pi, Rongbiao; Chan, Hugh H.N.; Fu, Hongjun; Lee, Nelson; Tsang, HingWai; Pu, Yongmei; Chang, Donald; Li, Chaoying; Luo, Jialie; Xiong, Keming; Li, Zhiwang; Xue, Hong; Carlier, Paul R.; Pang, Yuan-Ping; Tsim, Karl Wah Keung; Li, Mingtao; Han, Yifan Article
Orthogonal array design in optimizing the extraction efficiency of active constituents from roots of Panax notoginseng
Phytotherapy research, v. 19, (8), 2005, Aug, p. 684-688
Dong, Tina Tingxia; Zhao, Kuijun; Huang, W.Z.; Leung, Kawing; Tsim, Karl Wah Keung Article
Quantitative detection of gentiopicrin in Radix Gentianae
Shanghai Journal of Traditional Chinese medicine, v. 39, p.53-55
Chou, G.X.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wang, Z.T.; Yu, Z.L. Article
Regulation of PRiMA: membrane anchor of acetylcholinesterase (AChE) in neuron and muscle
Chemico-biological interactions, 2005, Dec, p. 157-158
Xie, Heidi Q.; Siow, Nina L.; Peng, H. Benjamin; Massoulié, Jean; Tsim, Karl Wah Keung Article
Species identification of Dyers woad leaf by DNA sequences of 5S-rRNA spacer domain and random amplified polymorphic DNA (RAPD)
Oriental Pharmacy and Experimental Medicine, v. 5, (2), p. 117-123
Zhao, K.J.; Dong, Tina Tingxia; Wong, Y.C.; Tu, P.F.; Tsim, Karl Wah Keung Article
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ in fast- and slow-twitch muscle fibers
Chemico-biological interactions, v. 157, (Sp. Iss. SI), 2005, DEC 15, p. 63-70
Ting, Annie; Siow, Nina L.; Kong, Lingwei; Tsim, Karl Wah Keung Article
三七中三七素的含量测定
中国药学杂志=Chinese Pharmaceutical Journal, v. 2005, 13, 2005, p. 1017-1019
崔秀明; 徐珞珊; 王强; 陈中坚; 董婷霞; 詹华强 Article
不同来源莪术中莪术醇、吉马酮、莪术二酮GC-MS定量分析
药物分析杂志=Chinese Journal of Pharmaceutical Analysis, v. 2005, (07), 2005, p. 827-830
杨丰庆; 李绍平; 陈莹; 刘倩青; 王一涛; 董婷霞; 詹华强 Article
(43) ATP induces the post-synaptic gene expression in neuron-neuron synapses: Transcriptional regulation of AChE catalytic subunit
Chemico-Biological Interactions, v. 157, 2005, p. 423-426
Siow, Nina Lam; Xie, Heidi Qunhui; Choi, Roy Chi Yan; Tsim, Karl Wah Keung Conference paper
(48) Regulation of PRiMA: Membrane anchor of acetylcholinesterase (AChE) in neuron and muscle
Chemico-Biological Interactions, v. 157, 2005, p. 432
Xie, Qunhui; Siow, Lam; Peng, Benjamin H; Massoulié, J.; Tsim, Karl Wah Keung Conference paper
A cAMP-dependent Signaling Directs the Post-Synaptic Expression of ColQ, a Subunit of Collagen-Tailed form AChE, at the Vertebrate Neuromuscular Junctions.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Ting, A.K.L.; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
A Flavonol Glycoside, Isolated from Roots of Panax Notoginseng, Protects the Beta-Amyloid-Induced Neurotoxicity in Cultured PC12 Cells
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Zhu, Judy T T; Leung, Ka Wing; Cheung, J.K.H.; Zhao, K.J.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
ATP induces post-synaptic gene expression in neuron-neuron synapses: the transcription regulation of NR2A subunit.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
Calcitonin gene-related peptide mediates synaptic expression of collagen-like subunit (COLQ) of acetylcholinesterase in muscle
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Ting, A.K.L.; Choi, Chi Yan; Lau, F.T.C.; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Characterization of chick AChE promoter: responses to nerve-derived factors
The 12th International Symposium on Cholinergic Mechanisms in Alicante, Spain, October 1-5, 2005
Wan, D.C.C.; Zhang, X.; Siow, Lam; Xie, H.Q.H.; Tsim, Karl Wah Keung Conference paper
Functional roles of P2Y1 receptor in cultured cortical neurons: regulation of AChE expression and small GTPase activation
Neuroscience 2005 in Washington, D.C., 12-16 Nov 2005
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
Identification of Critical Early Genes Involved in Nerve Growth Factor-Induced PC12 Differentiation
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5 - 6 December 2005
Xiao, Fang; Ng, Yu Pong; Tsim, Karl Wah Keung; Wise, Helen; Wong, Yung Hou; Ip, Nancy Yuk-Yu; Wu, Zhenguo Conference paper
NGF-Induced Neuronal Differentiation of PC12 Cells: Delineation of Signaling Molecules and Mapping of Pathways.
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5 - 6 December 2005
Leung, W.K.W.; Choi, Chi Yan; Ip, Nancy Yuk-Yu; Wu, Zhenguo; Wong, Yung Hou; Cheung, P.T.; Tsim, Karl Wah Keung Conference paper
Novel Dimeric Acetylcholinesterase Inhibitor Bis ( 7 ) - Tacrine Exerts Multiple Neuroprotective Activities by Inhibiting Nitric Oxide Synthase
35th Annual Meeting of the Society for Neuroscience, Washington Convention Center, Washington, DC (USA), 12-16 Nov 2005
Li, W.; Chan, H.H.N.; Xue, J.; Xue, Hong; Kan, K.K.W.; Zhao, Y.; Lee, N.T.K.; Luo, J.; Li, Z.; Carlier, P.R.; Pang, Y.; Tsim, Karl Wah Keung; Li, M.; Li, X.; Han, Yilong Conference paper
Regulation of collagen-like subunit (COLQ) of acetylcholinesterase by muscular activity in muscle
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Lau, F.T.C.; Ting, A.K.L.; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Regulation of NR2A, a subunit of N-methyl-d-aspartate receptor, by a cAMP-dependent signaling pathway in neuronal cultures
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Siow, Lam; Choi, Chi Yan; Xie, Qunhui; Tsim, Karl Wah Keung Conference paper
Regulation of P2Y1 Receptor: Signal Transduction, Dimerization, Desensitization and Internalization
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Choi, Chi Yan; Wong, Cecilia S.S.; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
Restricted Localization of P2Y1 Receptor in Cortical Neurons: Functional Role in Small GTPase Activation.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Ling, K.Y.; Kong, L.W.; Tsim, Karl Wah Keung Conference paper
Role of Calmodulin-Dependent Kinase II in Nerve Growth Factor-Induced Differentiation of PC12 Cells.
25th Annual Scientific Meeting of the Hong Kong Society of Neurosciences, Hong Kong, 5-6 December 2005
Kam, Yuet Fong; Yung, Ying; Wu, Eddy H.T.; Ng, Yu Pong; Wu, Zhenguo; Tsim, Karl Wah Keung; Wise, Helen; Ip, Nancy Yuk-Yu; Wong, Yung Hou Conference paper
Role of PRiMA in Regulating Globular Form of Acetylcholinesterase: The Possible Role of Ache Oligomeriztion
The 25th Annual Conference of The Hong Kong Society of Neurosciences, 5-6 December, 2005
Xie, Qunhui; Choi, Chi Yan; Siow, Lam; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
The expression and localization of PRiMA, a membrane anchor of acetylcholinesterase, during neuron and muscle differentiation
Neuroscience 2005 in Washington, D.C., 12-16 Nov 2005
Xie, Qunhui; Siow, Lam; Ting, A.K.L.; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Transcriptional control of different subunits of acetylcholinesterase in the formation and maintenance of vertebrate neuromuscular junctions
The 12th International Symposium on Cholinergic Mechanisms in Alicante, Spain, October 1-5, 2005
Tsim, Karl Wah Keung; Xie, Qunhui; Ting, A.K.L.; Siow, Lam; Lau, F.; Kong, L. Conference paper
Transcriptional regulation of PRiMA, a membrane anchor of globular form AChE, in neuron and muscle differentiation.
The 24th Annual Scientific Meeting of The Hong Kong Society of Neurosciences., Jan 2005
Xie, Qunhui; Siow, Lam; Ting, A.K.L.; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
2004 19
ATP potentiates agrin-induced AChR aggregation in cultured myotubes - Activation of RhoA in P2Y1 nucleotide receptor signaling at vertebrate neuromuscular junctions
Journal of biological chemistry, v. 279, (30), 2004, JUL 23, p. 31081-31088
Ling, KKY; Siow, Nina Lam; Choi, Roy Chi Yan; Ting, AKL; Kong, LW; Tsim, Karl Wah Keung Article
Chemical and biological assessment of a traditional Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis: Orthogonal array design to optimize the extraction of chemical constituents
Planta medica, v. 70, (12), 2004, DEC, p. 1222-1227
Song, Zong H.; Ji, Zhaoning; Lo, Chunkeung; Dong, Tina Tingxia; Zhao, Kuijun; Ll, O.T.W.; Haines, Christopher John; Kung, Shain D.; Tsim, Karl Wah Keung Article
Distinction of water-soluble constituents between natural and cultured Cordyceps by capillary electrophoresis
Phytomedicine, v. 11, (7-8), 2004, NOV, p. 684-690
Li, Shaoping; Song, Zong H.; Dong, Tina Tingxia; Ji, Zhaoning; Lo, Chunkeung; Zhu, Shangquan; Tsim, Karl Wah Keung Article
Identification and quantification of 13 components in Angelica sinensis (Danggui) by gas chromatography-mass spectrometry coupled with pressurized liquid extraction
Analytica Chimica Acta, v. 526, (2), 2004, Nov, p. 131-137
Lao, Sincheng; Li, Shaoping; Kan, Kelvin K.W.; Li, Peng; Wan, Jianbo; Wang, Yitao; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
P2Y(2) receptor activation regulates the expression of acetylcholinesterase and acetylcholine receptor genes at vertebrate neuromuscular junctions
Molecular pharmacology, v. 66, (4), 2004, OCT, p. 794-806
Tung, EKK; Choi, Roy Chi Yan; Siow, Nina Lam; Jiang, JXS; Ling, KKY; Simon, J.; Barnard, EA; Tsim, Karl Wah Keung Article
Simultaneous determination of ergosterol, nucleosides and their bases from natural and cultured Cordyceps by pressurised liquid extraction and high-performance liquid chromatography
Journal of chromatography A, v. 1036, (2), 2004, May, p. 239-243
Li, Shaoping; Li, Peng; Lai, C.M.; Gong, Yuanxiang; Kan, Kelvin K.W.; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wang, Yitao Article
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ - Differential expression in fast and slow twitch muscle fibers is driven by distinct promoters
Journal of biological chemistry, v. 279, (26), 2004, Jun, p. 27098-27107
Lee, Henry H.C.; Choi, Roy Chi Yan; Ting, Annie; Siow, Nina Lam; Jiang, Joy; Massoulié, Jean M.; Tsim, Karl Wah Keung Article
A formula of TCM: Danggui Buxe Tang
Takungpao, 19 February
Tsim, Karl Wah Keung Book
Modernization of Traditional Chinese Medicine: Problems in Safety and Quality Assurance
Vision of 2050: Agriculture in China / Edited by Tso et al. New York
Tsim, Karl Wah Keung; Kung, Shain-Dow Book chapter
The Biological and Pharmacological Properties of Cordyceps Sinensis, a Traditional Chinese medicine, that has Broad Clinical Applications
In: Herbal Medicines: Molecular Basis of Biological Activity and Health; Packer et al ed. Marcel Dekker Inc. New York / p. 657-682
Li, S.P.; Tsim, Karl Wah Keung Book chapter
The Role of P2Y1 Nucleotide Receptors in the Formation and Maintenance of the Skeletal Neuromuscular Junctions
Cholinergic Mechanisms / p. 105-110
Tsim, Karl Wah Keung; Choi, Chi Yan; Siow, Lam; Cheng, Anthony W.M.; Ling, Karen K Y; Tung, E.K.K.; Kong, L.W.; Barnard, E.A. Book chapter
Activation of P2Y1 Receptor Induces the Expression of AChE via MAP Kinase Signalling Pathway in Cultured Cortical Neurons
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 84
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
ATP Induces the Post-Synaptic Gene Expression in Neuron-Neuron Synapses: the Promoter Analysis of AChE Catalytic Subunit.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Siow, Lam; Xie, Qunhui; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
ATP-Activated Rho A GTPase Modulate Agrin-Induced AChR Aggregation
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 85
Ling, K.K.Y.; Choi, Chi Yan; Barnard, E.A.; Tsim, Karl Wah Keung Conference paper
PriMA, the Membrane Anchor of Acetylcholinesterase in the Brain: Characterization and Function
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 85
Xie, Qunhui; Genin, A.; Choi, Chi Yan; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Regulation of PRiMA, the Membrane Anchor of of Acetylcholiesterase, During Neuron and Muscle Differentiation.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Xie, Qunhui; Siow, Lam; Ting, A.K. L.,; Peng, Benjamin H; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Transcription Regulation of Collagen-Tailed Subunit of Acetylcholinesterase in Muscle
6th APSN meeting in Hong Kong, J. Neurochem, v. 88, (suppl), p. 85
Ting, A.K.L.; Lee, H.H.C.; Choi, Chi Yan; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
Transcriptional Regulation of AChE-Associated Collagen ColQ: Differential Expression in Fast-and Slow-Twitch Muscle Fibers is Driven by Distinct Promoters.
VIII International Meeting on Cholinesterases in Perugia, Italy., September 2004
Tsim, Karl Wah Keung Conference paper
Two Distinct Promoters of AChE Gene in Chicken are Responsible for Tissue-Specific Expression of Different Transcripts
6th APSN meeting in Hong Kong, J. Neurochem., v. 88, (suppl), p. 38
Tung, E.K.K.; Zhang, X.; Choi, Chi Yan; Tsim, Karl Wah Keung; Wan, D.C.C. Conference paper
2003 17
A polysaccharide isolated from Cordyceps sinensis, a traditional Chinese medicine, protects PC12 cells against hydrogen peroxide-induced injury
Life sciences, v. 73, (19), 2003, SEP 26, p. 2503-2513
Li, Shaoping; Zhao, Kuijun; Ji, Zhaoning; Song, Zong H.; Dong, Tina Tingxia; Lo, Chunkeung; Cheung, J.K.H.; Zhu, Shangquan; Tsim, Karl Wah Keung Article
ATP acts via P2Y(1) receptors to stimulate acetylcholinesterase and acetylcholine receptor expression: Transduction and transcription control
JOURNAL OF NEUROSCIENCE, v. 23, (11), 2003, JUN 1, p. 4445-4456
Choi, Roy Chi Yan; Siow, Nina Lam; Cheng, Anthony WM; Ling, Karen KY; Tung, EKK; Simon, J.; Barnard, EA; Tsim, Karl Wah Keung Article
ATP induces post-synaptic gene expressions in vertebrate skeletal neuromuscular junctions
Journal of neurocytology, v. 32, (5-8), 2003, JUN-SEP, p. 603-617
Tsim, Karl Wah Keung; Choi, Roy Chi Yan; Siow, Nina Lam; Cheng, AWM; Ling, KKY; Jiang, JXS; Tung, EKK; Lee, HHC; Xie, Heidi Qunhui; Simon, J.; Barnard, EA Article
Authentication of Panax notoginseng by 5S-rRNA spacer domain and random amplified polymorphic DNA (RAPD) analysis
Planta medica, v. 69, (6), 2003, Jun, p. 584-586
Cui, Xiuming; Lo, Chunkeung; Yip, K.L.; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
CDNA encodes Xenopus P2Y(1) nucleotide receptor: expression at the neuromuscular junctions
NeuroReport, v. 14, (3), 2003, MAR 3, p. 351-357
Cheng, Anthony WM; Kong, LW; Tung, EKK; Siow, Nina Lam; Choi, Roy Chi Yan; Zhu, SQ; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung Article
Characterization of a rhamnogalacturonan and a xyloglucan from Nerium indicum and their activities on PC12 pheochromocytoma cells
Journal of natural products, v. 66, (1), 2003, Jan, p. 7-10
Ding, Kan; Fang, Jinian; Dong, Tina Tingxia; Tsim, Karl Wah Keung; Wu, Houming Article
Chemical assessment of roots of Panax notoginseng in China: Regional and seasonal variations in its active constituents
Journal of agricultural and food chemistry, v. 51, (16), 2003, Jul, p. 4617-4623
Dong, Tina Tingxia; Cui, Xiuming; Song, Zong H.; Zhao, Kuijun; Ji, Zhaoning; Lo, Chunkeung; Tsim, Karl Wah Keung Article
Genetic distinction of Radix Adenophorae from its adulterants by the DNA sequence of 5S-rRNA spacer domains
American Journal of Chinese Medicine, v. 31, (6), 2003, p. 919-926
Zhao, Kuijun; Dong, Tina Tingxia; Cui, Xiuming; Tu, Pengfei; Tsim, Karl Wah Keung Article
Molecular genetic and chemical assessment of radix angelica (Danggui) in China
Journal of agricultural and food chemistry, v. 51, (9), 2003, Apr, p. 2576-2583
Zhao, Kuijun; Dong, Tina Tingxia; Tu, Pengfei; Song, Zong H.; Lo, Chunkeung; Tsim, Karl Wah Keung Article
Muscle induces neuronal expression of acetylcholinesterase in neuron-muscle co-culture - Transcriptional regulation mediated by camp-dependent signaling
Journal of biological chemistry, v. 278, (46), 2003, NOV 14, p. 45435-45444
Jiang, JXS; Choi, Roy Chi Yan; Siow, Nina Lam; Lee, HHC; Wan, DCC; Tsim, Karl Wah Keung Article
Phylogeny of Astragalus in China: Molecular evidence from the DNA sequences of 5S rRNA spacer, ITS, and 18S rRNA
Journal of agricultural and food chemistry, v. 51, (23), 2003, Nov, p. 6709-6714
Dong, Tina Tingxia; Ma, Xiaoqiang; Clarke, Clarles; Song, Zong H.; Ji, Zhaoning; Lo, Chunkeung; Tsim, Karl Wah Keung Article
Signalling pathways and ion channel regulations of P2Y receptors
Drug development research, v. 59, (1), 2003, MAY, p. 36-48
Barnard, Eric A.; Simon, Joseph; Tsim, Karl Wah Keung; Filippov, Alexander K.; Brown, David A. Article
建立评价当归质量的HPLC指纹图谱分析方法
中国药学杂志=Chinese Pharmaceutical Journal, v. 2003, (10), 2003
刘荣霞; 周婷婷; 董婷霞; 詹华强; 毕开顺 Article
Bis(7)-tacrine Attenuates Glutamate-Induced Apoptosis in Rat Cerebellar Granule Neurons by Regulating Calcium Homeostasis
Society for Neuroscience, 33rd Annual Meeting, New Orleans, LA, USA
Li, Wenming; Pi, Rongbiao; Chan, H.H.N.; Lee, N.T.K.; Tsang, H.W.; Pu, Y.M.; Wang, W.Y.; Chan, J.L.N.; Leung, W.C.; Xue, Hong; Chang, Donald C; Sucher, Nikolaus J.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Y. Conference paper
Prevention of b-amyloid-induced Neurotoxicity in Cultured PC12 Cells by Ginsenoside and Favonoid Isolated from Roots of Panax Notoginseng
11th Euroconferecne on Aptoptosis in Ghent, Belgium
Wan, D.C.C.; Ji, Z.N.; Song, Z.H.; Lo, Chun Keung; Cheung, J.K.H.; Dong, Ting Xia; Tsim, Karl Wah Keung Conference paper
PRiMA, the Membrane Anchor of Acetylcholinesterase in the Brain: Searching for its Proteic Partners Using the Yeast-two hybrid system
The 23rd Annual Scientifc Meeting, The Hong Kong Society of Neurosciences, Hong Kong, PP4, 9-10 December
Xie, Qunhui; Genin, Alexis; Choi, Chi Yan; Peng, Benjamin H; Massoulie, Jean; Tsim, Karl Wah Keung Conference paper
Transcriptional Regulation of Collagen-Tailed Subunit (ColQ) of Acetylcholinesterase (AChE) in Muscle
The 23rd Annual Conference of The Hong Kong Society of Neurosciences
Ting, A.K.L.; Lee, H.H.C.; Massoulie, J.; Tsim, Karl Wah Keung Conference paper
2002 21
A cyclic AMP-dependent pathway regulates the expression of acetylcholinesterase during myogenic differentiation of C2C12 cells
Journal of biological chemistry, v. 277, (39), 2002, SEP 27, p. 36129-36136
Siow, Nina Lam; Choi, Roy Chi Yan; Cheng, Anthony WM; Jiang, JXS; Wan, DCC; Zhu, SQ; Tsim, Karl Wah Keung Article
Chemical analysis of Radix Astragali (Huangqi) in China: A Comparison with its Adulterants and Seasonal Variations
Journal of agricultural and food chemistry, v. 50, (17), 2002, Aug, p. 4861-4866
Ma, Xia Q.; Shi, Q.; Duan, Jinao; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Determination of flavonoids in Pana notoginseng
Chinese Traditional and Herbal Drugs, v. 33, (7), p. 611-612
Cui, Xiu M.; Dong, Tina Tingxia; Huang, Wen Z.; Chen, Zhong J.; Tsim, Karl Wah Keung Article
Identification on Panax notoginseng and its adulterants by HPLC fingerprint chromatogram
Chin. Trad. and Herb. Drugs, v. 33, (10), p. 941-943
Cui, Xiu M.; Dong, Tina Tingxia; Chen, Zhong J.; Tsim, Karl Wah Keung Article
The development of TCM formula and patent drugs
Traditional Chinese Drug Research and Clinical Pharmacology, v. 13, (6), p. 343-345
Su, Ziren; Huang, Xiao D.; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The fruiting body and its caterpillar host of Cordyceps sinensis show close resemblance in main constituents and anti-oxidation activity
Phytomedicine, v. 9, (4), 2002, MAY, p. 319-324
Li, Shaoping; Su, Ziren; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The heat-induced degradation of magnolol and honokiol in supercritical fluid CO2 extraction from Magnolia bark
Yaoxue Xuebao, v. 37, (11), 2002, Nov, p. 870-875
Su, Ziren; Dong, Tina Tingxia; Lo, Chunkeung; Tsim, Karl Wah Keung Article
The signaling pathways mediated by P2Y nucleotide receptors in the formation and maintenance of the skeletal neuromuscular junction
NeuroSignals, v. 11, (1), 2002, JAN-FEB, p. 58-64
Tsim, Karl Wah Keung; Barnard, Eric A. Article
三七中黄酮成分的含量测定
中草药=Chinese Traditional and Herbal Drugs, v. 2002, (07), 2002
崔秀明; 董婷霞; 黄文哲; 陈中坚; 詹华强 Article
三七及其混淆品的HPLC指纹图谱鉴定
中草药=Chinese Traditional and Herbal Drugs, v. 2002, (10), 2002
崔秀明; 董婷霞; 陈中坚; 詹华强 Article
三七多糖成分的含量测定及其变化
中国药学杂志=Chinese Pharmaceutical Journal, v. 2002, (11), 2002
崔秀明; 董婷霞; 陈中坚; 王朝梁; 詹华强 Article
高温致厚朴SFE－CO2萃取物中厚朴酚、和厚朴酚降解
药学学报=Acta Pharmaceutica Sinica, v. 2002, (11), 2002, p. 870-875
苏子仁; 董婷霞; 卢振强; 詹华强 Article
Apoptosis in Rat Cerebellar Granule Neurons
Society for Neuroscience, 32nd Annual Meeting, Orlando, Florida
Li, Wenming; Chan, Hiu Nam; Lee, Tsz Kin Nelson; Xie, Y.B.; Ho, Chi Ming; Carlier, P.R.; Pang, Y.P.; Tsim, Karl Wah Keung; Li, M.T.; Han, Yi Fan Conference paper
ATP, Mediated by Rho A GTPase, Potentiates the Agrin-Induced AChR Aggregation in Cultured Chick Myotubes
22nd Annual Conference of The Hong Kong Society of Neurosciences
Ling, Karen K Y; Choi, Chi Yan; Tsim, Karl Wah Keung Conference paper
Expression and Localization of Different P2Y Receptors in Cultured Cortical Neurons
22nd Annual Conference of The Hong Kong Society of Neurosciences
Siow, Lam; Choi, Chi Yan; Barnard, Eric A.; Tsim, Karl Wah Keung Conference paper
Functional Roles of P2Y2 and P2Y4 Nucleotide Receptors in the Formation and Maintenance of the Neuromuscular Junctions
22nd Annual Conference of The Hong Kong Society of Neurosciences
Tung, Edmund K.K.; Choi, Chi Yan; Siow, Lam; Barnard, Eric A.; Tsim, Karl Wah Keung Conference paper
Huperzine A, a Promising Anti-Alzheimer's Agent, Reduces Staurosporine-Induced Apoptosis in NG108-15 Cells
XIth International symposium on cholinergic mechanisms-function and dysfunction & 2nd misrahi symposium on neurobiology, 5-9 May, St. Moritz, Switzerland
Han, Yi Fan; Xiao, Xiao-Qiu; Wu, Dong-Cheng; Gao, Yang; Ho, Wing-Lok; Lee, Tze-Kin Nelson; Fu, Yan; Tsim, Karl Wah Keung Conference paper
PriMA, the Membrane Anchor of AChE in the Brain: Searching for its Proteic Partners Using the Yeast-Two Hybrid System
22nd Annual Conference of The Hong Kong Society of Neurosciences
Xie, Qui H.; Genin, Alexis; Peng, Benjamin H; Massoulie, Jean; Tsim, Karl Wah Keung Conference paper
Regulation of Neuronal AChE Expression by Muscle in Neuron-Muscle Co-Cultures
22nd Annual Conference of The Hong Kong Society of Neurosciences
Jiang, Joy X.S.; Tsim, Karl Wah Keung Conference paper
The Transcriptional Regulation of Collagen-Tailed (ColQ), a Subunit of Asymmetric Acetylcholinesterase is Muscle Fibre-Type-Specific Dependent
22nd Annual Conference of The Hong Kong Society of Neurosciences
Lee, Henry H.C.; Genin, Alexis; Tsim, Karl Wah Keung Conference paper
Two Alternative Promoters for Chicken Acetylcholinesterase Gene and Tissue-Specific Transcription
22nd Annual Conference of The Hong Kong Society of Neurosciences
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C. Conference paper
2001 22
Advance of Anti-tumor for Cordyceps sinensis
Chinese Traditional & Herbal Drugs, v. 32, p. 373-375
Li, Shao Ping; Ji, Hui; Li, Ping; Dong, Tina Ting Xia; Tsim, Karl Wah Keung; Li, Wen Qi Article
Anti-oxidation activity of different types of natural Cordyceps sinensis and cultured Cordyceps mycelia
Phytomedicine, v. 8, (3), 2001, May, p. 207-212
Li, Shao Ping; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Authentic Identification of Stigma Croci (Stigma of Crocus sativus) from its Adulterants by Molecular Genetic Analysis
Planta medica, v. 67, (2), 2001, Mar, p. 183-186
Ma, Xia Q.; Zhu, Dayuan; Li, Shao Ping; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction
Nature Neuroscience, v. 4, (4), April 2001, p. 374-381
Fu, Amy Kit Yu; Fu, Wing Yu; Cheung, Janet; Tsim, Karl Wah Keung; Ip, Fanny Chun Fun; Wang, Jerry Hsueh-ching; Ip, Nancy Yuk-Yu Article
Chips and Qi: Microcomponent-Based Analysis in Traditional Chinese Medicine
Fresenius Journal of Analytical Chemistry, v. 371, (2), September 2001, p. 190-194
Carles, Maria; Lee, Ming Hung Thomas; Moganti, Shanti; Lenigk, Ralf; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu; Hsing, I-Ming; Sucher, Nikolaus J. Article
Comments on the change of drug nature and innovation of Chinese patent drugs in the preparing process
Traditional Chinese Drug Research and Clinical Pharmacology, v. 13, p. 1-4
Su, Ziren; Chen, Jiannan; Shen, Xiaoling; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Determination of nucleosides in natural Cordyceps sinensis and cultured Cordyceps mycelia by capillary electrophoresis
Electrophoresis, v. 22, (1), 2001, p. 144-150
Li, Shao Ping; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Determination of water-soluble constituents from the drug materials of 'Honghua'
Journal of Pharmaceutical Practice, v. 18, p. 310-311
Ma, Xiaoqing; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Expression of the P2Y1 nucleotide receptor in chick muscle: Its functional role in the regulation of acetylcholinesterase and acetylcholine receptor
Journal of Neuroscience, v. 21, (23), December 2001, p. 9224-9234
Choi, Roy Chi Yan; Man, Menlisa L.S.; Ling, Karen K.Y.; Ip, Nancy Yuk-Yu; Simon, Joseph; Barnard, Eric A.; Tsim, Karl Wah Keung Article
The contents and their change of nucleosides from natural Cordyceps sinensis and cultured Cordyceps mycelia
Yaoxue Xuebao, v. 36, (6), 2001, June, p. 436-439
Li, Shao Ping; Li, Ping; Ji, Hui; Zhang, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The Cyclic AMP-Mediated Expression of Acetylcholinesterase in Myotubes Shows Contrasting Activation and Repression between Avian and Mammalian Enzymes
Molecular and Cellular Neuroscience, v. 17, (4), April 2001, p. 732-745
Choi, Roy Chi Yan; Siow, Nina Lam; Zhu, Shangquan; Wan, David Chi Cheong; Wong, Yung Hou; Tsim, Karl Wah Keung Article
The Nucleosides Contents and Their Variation in Natural Cordyceps sinensis and Cultured Cordyceps Mycelia
Journal of Chinese Pharmaceutical Sciences=药学学报, v. 10 , (4), 2001, p. 175-179
Li, Shaoping; Li, Ping; Ji, Hui; Zhu, Quan; Dong, Tina T.X.; Tsim, Karl Wah Keung Article
The nucleotides contents and their variation in natural Cordyceps sinensis and cultured Cordyceps mycelia
Journal of Chinese Pharmaceutical Sciences, v. 10, (4), 2001, p. 175-179
Li, Shaoping; Li, Ping; Ji, Hui; Zhang, Ping; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
The separation and reconstitution of active ingredients of TCM
Chinese Traditional Patent Medicine, 23: 615-616
Su, Ziren; Dong, Tina Tingxia; Chan, Jian Nan; Tsim, Karl Wah Keung Article
冬虫夏草抗肿瘤作用研究进展
中草药, v. 32, (4), 2001, p. 373-375
李绍平; 季晖; 李萍; 董婷霞; 詹华强; 李文琪 Article
毛细管电泳法测定冬虫夏草中核苷类的含量
药物分析杂志, v. 21, (2), 2001, p. 77-79
李绍平; 李萍; 季晖; 董婷霞; 詹华强 Article
Analysis of Carbohydrates from Natural Cordyceps Sinensis and Cultured Cordyceps Mycelia by HPLC
Forum of Modern Pharmaceutical Analysis, Xinhua Press, Beijing / p. 149-151
Li, Shao Ping; Dong, Ting Xia; Su, Zi Ren; Zhu, Quan; Tsim, Karl Wah Keung Book chapter
Cloning and Characterization of Acetylcholinesterase Gene in Chicken
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C. Conference paper
Cloning of Chicken Acetylcholinesterase Gene and Characterization of its Putative Promoter Activity
The 21st Annual Conference of The Hong Kong Society of Neurosciences
Zhang, Xiang; Tsim, Karl Wah Keung; Wan, David C.C. Conference paper
NFkB Regulates the Activity of Human Acetylcholinesterase Promoter in Muscle
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Choi, Chi Yan; Siow, Lam; Cheng, Anthony W.M.; Zhang, Xiang; Wan, David C.C.; Tsim, Karl Wah Keung Conference paper
Regulation of AChR and AChE by of P2Y1 Nucleotide Receptor During the Formation of Neuromuscular Junctions
Annual Meeting Society for Neurosciences (USA), 2001-2002
Tsim, Karl Wah Keung; Choi, Chi Yan; Ling, Karen; Kong, Ling Wei; Barnard, Eric Conference paper
The Role of P2Y Nucleotide Receptors in the Formation of Neuromuscular Junctions
XIth International symposium on Cholinergic Mechanism-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
Tsim, Karl Wah Keung; Barnard, Eric Conference paper
2000 7
Authentication of an animal crude drug, Zaocys, by diagnostic PCR
Biological & pharmaceutical bulletin, v. 23, (5), 2000, May, p. 585-588
Wang, Yiquan; Zhou, Kaiya; Xu, Luoshan; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Chemical comparison of Astragali Radix (Huangqi) from Different Regions of China
Natural Medicines, v. 54, (5), 2000, p. 213-218
Ma, Xia Q.; Duan, Jinao; Zhu, Dayuan; Dong, Ting Xia; Tsim, Karl Wah Keung Article
Immunoglobulin G1 Fc Fragment-Tagged Human Opioid Receptor-Like Receptor Retains the Ability to Inhibit cAMP Accumulation
Biological Signals and Receptors, v. 9, (5), September-October 2000, p. 240-247
Yung, Ying; Tsim, Karl Wah Keung; Pei, Gang; Wong, Yung Hou Article
Species identification of Radix Astragali (Huangqi) by DNA sequence of its 5S-rRNA spacer domain
Phytochemistry, v. 54, (4), 2000, Jun, p. 363-368
Ma, Xiaoqiang; Duan, Jinao; Zhu, Dayuan; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
The cAMP-dependent protein kinase mediates the expression of AChE in chick myotubes
NeuroReport, v. 11, (4), 2000, MAR 20, p. 801-806
Choi, Roy Chi Yan; Siow, Nina Lam; Zhu, SQ; Tsim, Karl Wah Keung Article
The promoter of human acetylcholinesterase is activated by a cyclic adenosine 3 `,5 `-monophosphate-dependent pathway in cultured NG108-15 neuroblastoma cells
Neuroscience Letters, v. 288, (1), 2000, JUL 7, p. 81-85
Wan, DCC; Choi, Roy Chi Yan; Siow, Nina Lam; Tsim, Karl Wah Keung Article
贝母的分子生物学鉴定方法的研究
药学学报=Acta Pharmaceutica Sinica, v. 35, (4), 2000, p. 309-312
蔡朝晖; 李 萍; 董婷霞; 詹华强 Article
1999 5
A cysteine-rich form of Xenopus neuregulin induces the expression of acetylcholine receptors in cultured myotubes
Molecular and Cellular Neuroscience, v. 13, (6), June 1999, p. 415-429
Yang, Jiefei; Zhou, Hong; Choi, Roy Chi Yan; Ip, Nancy Yuk-Yu; Peng, Benjamin Hsiao Ming; Tsim, Karl Wah Keung Article
Lack of allelic association of dopamine D4 receptor gene polymorphisms with Parkinson's disease in a Chinese population
Movement disorders, v. 14, (2), 1999, Mar, p. 225-229
Wan, David Chi Cheong; Law, Lapkay; Ip, Denis; Cheung, W. T.; Ho, Walter; Tsim, Karl Wah Keung; Kay, Richard; Woo, Jean; Pang, Chipui Article
Molecular diversity of 5S-rRNA spacer domain in Fritillaria species revealed by PCR analysis
Planta medica, v. 65, (4), 1999, May, p. 360-364
Cai, Zhaohui; Li, Ping; Dong, Tina Tingxia; Tsim, Karl Wah Keung Article
Xenopus muscle-specific kinase: molecular cloning and prominent expression in neural tissues during early embryonic development
European Journal of Neuroscience, v. 11, (2), February 1999, p. 373-382
Fu, Amy Kit Yu; Smith, Frances D.; Zhou, Hong; Chu, Apple H.; Tsim, Karl Wah Keung; Peng, Benjamin H.; Ip, Nancy Yuk-Yu Article
蒲圻贝母组织培养鳞茎形成过程中生理生化变化研究
武汉植物学研究, v. 1999, (04), 1999, p. 314-318
蔡朝晖; 李萍; 李会军; 高山林; 董婷霞; 詹华强 Article
1998 3
Cloning of cDNAs encoding Xenopus neuregulin: expression in myotomal muscle during embryo development
Molecular Brain Research, v. 58, (1-2), July 1998, p. 69-73
Yang, Jiefei; Zhou, Hong; Pun, San; Ip, Nancy Yuk-Yu; Peng, H. Benjamin; Tsim, Karl Wah Keung Article
Over-expression of acetylcholinesterase stimulates the expression of agrin in NG108-15 cells
Neuroscience Letters, v. 248, (1), 1998, MAY 22, p. 17-20
Choi, Roy Chi Yan; Yam, SCY; Hui, BD; Wan, DCC; Tsim, Karl Wah Keung Article
The calcitonin gene-related peptide-induced acetylcholinesterase synthesis in cultured chick myotubes is mediated by cyclic AMP
Journal of Neurochemistry, v. 71, (1), July 1998, p. 152-160
Choi, Roy Chi Yan; Yung, Lisa Ying; Dong, Tina Ting Xia; Wan, David C.C.; Wong, Yung Hou; Tsim, Karl Wah Keung Article
1997 12
A globular, not a symmetric, form of acetylcholinesterase is expressed in chick motor neurons: Down-regulation toward maturity and after denervation
Journal of neurochemistry, v. 68, (2), 1997, FEB, p. 479-487
Tsim, Karl Wah Keung; Choi, Roy Chi Yan; Dong, Tina Ting Xia; Wan, DCC Article
A role of midkine in the development of the neuromuscular junction
Molecular and Cellular Neurosciences, v. 10, (1-2), 1997, p. 56-70
Zhou, Hong; Muramatsu, Takashi; Halfter, Willi M.; Tsim, Karl Wah Keung; Peng, H. Benjamin Article
Agrin-deficient myotube retains its acetylcholine receptor aggregation ability when challenged with agrin
Journal of Neurochemistry, v. 69, (6), December 1997, p. 2555-2563
Pun, San; Ng, Yu Pong; Yang, Jiefei; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung Article
Antisense agrin cDNA transfection blocks neuroblastoma cell-induced acetylcholine receptor aggregation when co-cultured with myotubes
Molecular and Cellular Neurosciences, v. 10, (1-2), 1997, p. 87-99
Pun, San; Tsim, Karl Wah Keung Article
Chick muscle expresses various ARIA isoforms: Regulation during development, denervation, and regeneration
Molecular and Cellular Neurosciences, v. 9, (2), 1997, p. 132-143
Ng, Yu Pong; Pun, San; Yang, Jiefei; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung Article
Denervation decreases the ipsilateral expression of AChE in chick lumbaric motor neurons
Neuroscience Letters, v. 232, (2), 1997, AUG 29, p. 83-86
Wan, DCC; Ng, Yu Pong; Choi, Roy Chi Yan; Cheung, PWT; Dong, Tina Ting Xia; Tsim, Karl Wah Keung Article
Expression and localization of endothelin converting enzyme in rat vas deferens
Life sciences, v. 60, (18), 1997, Mar, p. 1605-1612
Wan, David Chi Cheong; Luk, Sandy Ka Shing; Tsim, Karl Wah Keung; Cheung, W. T. Article
Muscle-derived neurotrophin-3 increases the aggregation of acetylcholine receptors in neuron-muscle co-cultures
NeuroReport, v. 8, (18), December 1997, p. 3895-3900
Fu, Amy Kit Yu; Ip, Fanny Chun Fai; Lai, Kwok On; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu Article
NG108-15 cells express neuregulin that induces AChR alpha-subunit synthesis in cultured myotubes
FEBS letters, v. 418, (3), 1997, Dec, p. 275-281
Pun, San; Yang, Jiefei; Ng, Yupong; Tsim, Karl Wah Keung Article
NG108-15 cells induce the expression of muscular acetylcholinesterase when co-cultured with myotubes
Neuroscience Letters, v. 236, (3), 1997, NOV 7, p. 167-170
Choi, Roy Chi Yan; Pun, S.; Dong, Tina Ting Xia; Wan, DCC; Tsim, Karl Wah Keung Article
The EGF-like domain of chick acetylcholine receptor-inducing activity (ARIA) contains its full biological activity
FEBS Letters, v. 403, (2), February 1997, p. 163-167
Yang, Jiefei; Ng, Yu Pong; Pun, San; Ip, Nancy Yuk-Yu; Tsim, Karl Wah Keung Article
组培蒲圻贝母鳞茎形成过程中的同工酶电泳分析
中国中药杂志, v. 1997, (01), 1997
蔡朝晖; 高山林; 李萍; 董婷霞; 詹华强 Article
1996 4
Calcitonin gene-related peptide increases the expression of acetylcholinesterase in cultured chick myotubes
Neuroscience Letters, v. 217, (2-3), 1996, OCT 18, p. 165-168
Choi, Roy Chi Yan; Leung, PWY; Dong, Tina Ting Xia; Wan, DCC; Tsim, Karl Wah Keung Article
Cerebellar granule cells express a specific isoform of agrin that lacks the acetylcholine receptor aggregating activity
FEBS letters, v. 379, (1), 1996, Jan, p. 63-68
So, K. L.; Pun, San; Wan, David Chi Cheong; Tsim, Karl Wah Keung Article
Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury
Journal of Neurochemistry, v. 67, (4), October 1996, p. 1607-1612
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu Article
Extracellular and asymmetric forms of acetylcholinesterase are expressed on cholinergic and noncholinergic terminal neuropil of the developing chick retina
Cell and Tissue Research, v. 286, (1), 1996, Oct, p. 13-22
Rei?, Yvonne; Kr?ger, Stephan; Grassi, Jaques; Tsim, Karl Wah Keung; Willbold, Elmar; Layer, Paul Gottlob Article
1995 3
Cloning of the α component of the chick ciliary neurotrophic factor receptor: Developmental expression and down-regulation in denervated skeletal muscle
Journal of Neurochemistry, v. 65, (6), December 1995, p. 2393-2400
Ip, Fanny Chun Fun; Fu, Amy Kit Yu; Tsim, Karl Wah Keung; Ip, Nancy Yuk-Yu Article
Prenatal cocaine exposure revealed minimal postnatal changes in rat striatal dopamine D2 receptor sites and mRNA levels in the offspring
Molecular Neurobiology, v. 11, (1-3),p. 67-76
Stadlin, Alfreda; Choi, Heung Ling; Tsim, Karl Wah Keung; Tsang, David Article
Truncated form of pro-acetycholine receptor-inducing activity (ARIA) induces AChR α-subunit but not AChE transcripts in cultured chick myotubes
Neuroscience Letters, v. 198, (2), 1995, Sep, p. 107-110
Pun, San; Tsim, Karl Wah Keung Article
1992 3
cDNA that encodes active agrin
Neuron, v. 8, (4), 1992, Apr, p. 677-690
Tsim, Karl Wah Keung; Rüegg, Markus Andreas; Escher, Gérard; Kr?ger, Stephan; McMahan, Uel Jackson Article
The agrin gene codes for a family of basal lamina proteins that differ in function and distribution
Neuron, v. 8, (4), 1992, p. 691-699
Rüegg, Markus Andreas; Tsim, Karl Wah Keung; Horton, Sharon E.; Escher, Gérard; Kr?ger, Stephan; McMahan, Uel Jackson Article
Transcripts for the acetylcholine receptor and acetylcholine esterase show distribution differences in cultured chick muscle cells
Journal of Cell Biology, v. 118, (5), 1992, p. 1201-1212
Tsim, Karl Wah Keung; Greenberg, Ian B.; Rimer, Mendell; Randall, William R.; Salpeter, Miriam M. Article
1989 1
Regulation of acetylcholine receptors and acetylcholinesterase in the innervation of skeletal muscle
Neuromuscular Junction., v. 13, 2004, p. 499-514
Barnard, Eric A.; Beeson, David M W; Darlison, Mark G.; Moss, Stephen J.; Randall, W. R.; Tsim, Karl Wah Keung Article
1988 5
Acetylcholinesterase antibodies and thyroid autoimmunity
Clin Exp Immunol, v. 71, 1988, p. 96-99
Weetman, AP; Tse, CK; Randall, WR; Tsim, Karl Wah Keung; Barnard, EA Article
An asymmetric form of muscle acetylcholinesterase contains three subunit types and two enzymic activities in one molecule
Proceedings of the National Academy of Sciences of the United States of America, v. 85, (4), 1988, p. 1262-1266
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A. Article
Identification of a 17S asymmetric butyrylcholinesterase in chick muscle by monoclonal antibodies
Neurosci Lett, v. 86, 1988, p. 245-249
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A. Article
Monoclonal antibodies specific for the different subunits of asymmetric acetylcholinesterase from chick muscle.
Journal of Neurochem, v. 51, (1), 1988, p. 95-104
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A. Article
Synaptic acetylcholinesterase of chicken muscle changes during development from a hybrid to a homogeneous enzyme
EMBO Journal, v. 7, (8), 1988, p. 2451-2456
Tsim, Karl Wah Keung; Randall, William R.; Barnard, Eric A. Article
1987 1
Monoclonal antibodies against chicken brain acetylcholinesterase: their use in immunopurification and immunochemistry to demonstrate allelic variants of the enzyme
European Journal of Biochemistry, v. 164, (1), 1987, p. 95-102
Randall, William R.; Tsim, Karl Wah Keung; Lai, Josephine; Barnard, Eric A. Article
1985 2
Prolactin receptor in rat liver: Sex difference in estrogenic stimulation and imprinting of the responsiveness to estrogen by neonatal androgen in male rats
Molecular and Cellular Endocrinology, v. 40, (2-3), p. 99-105
Tsim, Karl Wah Keung; Pak, Raphael; Cheng, Christopher Hon Ki Article
The role of neonatal and pubertal gonadal hormones in regulating the sex dependence of the hepatic microsomal testosterone 5-reductase activity in the rat
Journal of Endocrinology, v. 106, (1), p. 71-79
Pak, Raphael; Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki Article
1984 3
Evidence for the involvement of essential sulphydryl group in rat hepatic lactogenic receptor but not in somatogenic receptor
Molecular and Cellular Endocrinology, v. 38, (1), 1984, p. 61-66
Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki Article
Pubertal gonadal hormones in modulating the testosterone dependency of hepatic aryl hydrocarbon hydroxylase in female rats
Pharmacology, v. 29, (3), 1984, p. 121-127
Pak, Raphael; Tsim, Karl Wah Keung; Cheng, Christopher Hon Ki Article
Rat hepatic prolactin receptor: Pubertal exposure to sex steroid alters responsively to testosterone
Int J Peptide Protein Res, v. 23, 1984, p. 521-527
Cheng, Christopher H. K.; Tsim, Karl Wah Keung; Wai, M. K. Article
No Publications
Teaching Assignment
2021-22 Winter 0 2021-22 Fall 8 2020-21 Summer 2 2020-21 Spring 9 2020-21 Winter 1 2020-21 Fall 13
LIFS2070 Introduction to Biotechnology
LIFS4200 Concepts and Issues in Contemporary Biotechnology
LIFS4820 Entrepreneurship in Biotechnology
LIFS4961 Biochemistry and Cell Biology Capstone Project
LIFS4971 Biochemistry and Cell Biology Project Research I
LIFS6114E Current Topics in Biotechnology and Traditional Chinese Medicine
UROP1100E Undergraduate Research Opportunities Series 1
UROP2100E Undergraduate Research Opportunities Series 2
LIFS3520 Junior Research Project II
LIFS4963 Biotechnology Capstone Project
BIBU4850 Biotechnology and Business Project Research
LIFS3510 Junior Research Project I
LIFS4960 Biological Science Capstone Project
LIFS4963 Biotechnology Capstone Project
LIFS4980 Biological Science Project Research II
LIFS4981 Biochemistry and Cell Biology Project Research II
LIFS4983 Biotechnology Project Research II
LIFS5260 Biochemical and Molecular Basis of Diseases
LIFS6111N Life Science Postgraduate Student Seminar
ENTR4901Q Student-led Entrepreneurship Acceleration Project
BIBU4840 Biotechnology and Business Capstone Project
BIBU4850 Biotechnology and Business Project Research
BTEC5550 Nutraceuticals and Transgenic Products
LIFS2070 Introduction to Biotechnology
LIFS4200 Concepts and Issues in Contemporary Biotechnology
LIFS4820 Entrepreneurship in Biotechnology
LIFS4960 Biological Science Capstone Project
LIFS4963 Biotechnology Capstone Project
LIFS4970 Biological Science Project Research I
LIFS4971 Biochemistry and Cell Biology Project Research I
LIFS4973 Biotechnology Project Research I
LIFS5070 Workshops in Biosciences
LIFS6114D Current Topics in Biotechnology and Traditional Chinese Medicine
No Teaching Assignments
Research Postgraduate (RPG) Supervision From January 2019 to December 2022 (As of 30 January 2022)
All Supervisions Current RPGs Graduated RPGs
Current RPGs
Doctor of Philosophy CHEN, Yanxian
Life Science( 2021 - )
WU, Jiahui
Life Science( 2021 - )
CHENG, Hok Chi
Life Science( 2020 - )
LAU, Eugene Yu Shing
Life Science( 2020 - )
OSPONDPANT, Dusadee
Life Science( 2020 - )
SUN, Anqi
Life Science( 2020 - )
XIA, Chenxi
Life Science( 2020 - )
YUEN, Ka Wing Gary
Life Science( 2020 - )
GAO, Xiong
Life Science( 2019 - )
GUO, Suisui
Life Science( 2019 - )
XIA, Yingjie
Life Science( 2019 - )
LAI, Wing Sze
Life Science( 2018 - )
Master of Philosophy KONG, Ivan
Life Science( 2021 - )
ZHANG, Hoi Lam
Life Science( 2020 - )
Graduated RPGs
Doctor of Philosophy LI, Yunlong
Life Science( Completed in 2021 )
XIA, Yiteng
Life Science( Completed in 2021 )
KWAN, Kin Leung
Life Science( Completed in 2020 )
WU, Qiyun
Life Science( Completed in 2020 )
YU, Xiaodan
Life Science( Completed in 2020 )
HU, Weihui
Life Science( Completed in 2019 )
LIU, Yunle
Life Science( Completed in 2019 )
Master of Philosophy YUAN, Liuliang
Life Science( Completed in 2021 )
ProjectsFrom January 2020 to December 2022
All Projects 23 Leading Projects 13 Participating Projects 10
Cholinergic Regulation of Melanogenesis in Skin Synapse - an Interplay between Keratinocyte and Melanocyte
皮肤突触系统中黑色素生成的胆硷能调控作用-角质细胞和黑色素细胞之间的相互作用 Leading
RGC - General Research Fund
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2022 -
Application of SGC Technology in Non-human Species: A Novel Method to Develop New Skincare Products for Global Market
SGC技术在非人物种的应用：开发新型护肤产品全球市场的新方法 Leading
Innovation and Technology Fund
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2021 -
Survey of Environmental Pollution from Aristolochic Acids in Herbal Medicine Cultivation areas of Mainland China Participating
The TUYF Charitable Trust
Project Team (HKUST)
CHAN Simon Wan (Lead)
TSIM Karl Wah Keung
2021 -
Development of Novel Advanced Therapy Medicinal Products for Neurodegenerative Diseases
研发用於神经退行性疾病的新型先进疗法药物 Leading
Innovation and Technology Fund
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2021 -
Identification of Lingnan Chinese medicines against COVID-19 infection
具抗新冠病毒功效的岭南药材的探讨研究 Leading
Health and Medical Research Fund
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
BANFIELD David Karl
MILLER Andrew Leitch
2020 -
Research & Development of Traditional Chinese Medicine Classics formula——Data Platform Establishing
经典名方作用机理、物质基准和二次开发研究——数据平台的建立 Leading
Nanhai People's Government of Foshan
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
CHAN Simon Wan
LAM Henry Hei Ning
WANG Yang
2020 -
Research on International Standards of Eight Traditional Chinese Medicines with Guangdong Characteristics
蛹虫草、虫草菌粉、溪黄草、枸杞、天麻、香橼、小叶榕和蒲公英等8种药材国际质量标准体系建立 Participating
Department of Science and Technology of Guangdong Province
Project Team (HKUST)
TSIM Karl Wah Keung
2020 -
A Stem Cell Approach to Dissect the Molecular Basis of Neurodegenerative Diseases
以干细胞方法解析神经退行性疾病的分子基础 Participating
RGC - Theme-based Research Scheme
Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHEUNG Tom
CHUNG Kenny K
FU Amy Kit Yu
QI Robert Zhong
QU Jianan
TSIM Karl Wah Keung
WEN Zilong
WONG Yung Hou
WU Zhenguo
XIA Jun
2019 -
New Feed Additives - Industrialization of Vine Tea flavonoids in Marine Aquaculture
新型饲料添加剂-藤茶黄酮在海水养殖中的产业化开发 Participating
Guangzhou Municipal Science and Technology Bureau
Project Team (HKUST)
TSIM Karl Wah Keung
2019 -
Chemical chaperones of AChE inhibitors in the assembly of AChE in neurons: a possible cell death inducer for current anti-Alzheimer's disease drugs Leading
Health and Medical Research Fund
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2019 - 2021
Development of Probiotic Products against Dermatitis
开发益生菌抗湿疹产品 Leading
Innovation and Technology Fund
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2019 - 2021
Polydatin and its Related Analogues in the Treatment of Age-related Macular Degeneration
虎杖苷及其类似物对老年黄斑病变的治疗功效 Leading
Bio-Gene Technology Limited, Innovation and Technology Fund
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2019 - 2021
Preclinical study of a novel selected compound PT109 against Alzheimer's disease
新型候选化合物PT109抗阿尔茨海默氏病的临床前研究 Participating
Guangzhou Municipal Science and Technology Bureau, Zhaoke (Guangzhou) Pharmaceutical Co., Ltd.
Project Team (HKUST)
TSIM Karl Wah Keung
2018 -
Recognition of the role of aristolochic acids poisoning in chronic kidney disease observed in China
阐明马兜铃酸中毒在中国慢性肾脏疾病中扮演的角色 Participating
The TUYF Charitable Trust
Project Team (HKUST)
CHAN Simon Wan
LAU Stanley Chun Kwan
TSIM Karl Wah Keung
YU Jianzhen
2018 -
Design, develop and pilot the use of a domestic wastewater treatment unit suitable for a rural environment in developing countries (the "DWTU") Leading
The TUYF Charitable Trust
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2018 - 2021
Source Identification of Metal Pollution in the Pearl River Estuary
珠江口不同重金属污染物的来源 Leading
The TUYF Charitable Trust
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2018 - 2021
Shenzhen Key Laboratory of Edible and Medicinal Resources
深圳市可食用及药用资源研究重点实验室 Leading
Shenzhen Science and Technology Innovation Committee
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
LI Ning
ZHU Guang
2018 - 2020
Biogeochemical Cycling in the U-shaped Ocean Ridge Hydrothermal Vent Ecosystem
U形区洋中脊生态系统监测保护-课题五：U形区洋中脊热液区不同生态系统生物地球化学循环 Participating
China Ocean Mineral Resources R&D Association
Project Team (HKUST)
TSIM Karl Wah Keung
2018 - 2020
Research on modernization and application of Angong Niuhuang Pill
安宫牛黄丸的现代研究及应用 Participating
Guangzhou Baiyunshan Zhongyi Pharmaceutical Co. Ltd., Guangzhou Municipal Science and Technology Bureau
Project Team (HKUST)
TSIM Karl Wah Keung
2017 -
Research on traditional Chinese medicine Leading
Private Donor
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2017 -
Research of alkaloids of traditional Chinese medicine (TCM) and its biological activity
基20170326中药生物碱类成分及生物活性研究 Leading
Shenzhen Science and Technology Innovation Committee
Project Team (HKUST)
TSIM Karl Wah Keung (Lead)
2017 - 2020
Hong Kong Branch of National Engineering Research Center for Tissue Restoration & Reconstruction
国家人体组织功能重建工程技术研究中心香港分中心 Participating
Innovation and Technology Fund
Project Team (HKUST)
SUN Jianwei (Lead)
CHAU Ying
GUO Zhihong
HSING I-ming
IP Nancy Yuk-Yu
JIA Guocheng
KO Robert Kam Ming
KWOK Ryan Tsz Kin
LAM Wing Yip
LIANG Chun
LIN Nian
LUO Zhengtang
MI Yongli
TSIM Karl Wah Keung
WILLIAMS Ian Duncan
WU Hongkai
WU Zhenguo
YAN Henry He
YAN Yan
YANG Jinglei
YAO Shuhuai
2015 -
State Key Laboratory of Molecular Neuroscience (The Hong Kong University of Science and Technology)
分子神经科学国家重点实验室（香港科技大学） Participating
Innovation and Technology Fund
Project Team (HKUST)
IP Nancy Yuk-Yu (Lead)
CHOW King Lau
CHUNG Kenny K
DAI Wei Min
GUO Zhihong
HUANG Pingbo
LIANG Chun
MILLER Andrew Leitch
POON Randy Yat Choi
QI Robert Zhong
TSIM Karl Wah Keung
WEN Zilong
WONG Joseph Tin Yum
WONG Yung Hou
WU Zhenguo
ZHU Guang
2011 -
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香港科技大学理学院老师教师导师介绍简介-Karl Wah Keung TSIM
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