Dr Law Ga-lai Associate Professor

Location Y821
Phone +852 3400 8680
mail ga-lai.law@polyu.edu.hk

Open Platform for University Scholars
ORCID ID
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Education and Academic Qualifications Doctor of Philosophy, The University of Hong Kong
Master of Chemistry, The University of Manchester




Research Overview My research focus on three major areas: Chemical-Biology, f elements and Luminescence to develop new luminescent materials as well as multimodal imaging probes.




Academic and Professional Experiences Professional membershipof RSC, The Royal Society of Chemistry and ACS, American Chemical Society




Research Interests
Chemical Biology
Inorganic Chemistry with F-Block Elements and Luminescent Materials
Chiral Compounds Materials
Molecular Imaging



Achievements

Representative Publications
Dai LX, Jones CM, Chan WTK, Pham TA, Ling XX, Gale EM, Rotile NJ, Tai WCS, Anderson CJ, Caravan P, Law GL. Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications. Nature Communications. 2018;9.
Yeung CT, Yim KH, Wong HY, Pal R, Lo WS, Yan SC, Wong MYM, Yufit D, Smiles DE, McCormick LJ, Teat SJ, Shuh DK, Wong WT, Law GL. Chiral transcription in self-assembled tetrahedral Eu4L6 chiral cages displaying sizable circularly polarized luminescence. Nature Communications. 2017;8.
Li H, Xie C, Lan R, Zha S, Chan CF, Wong WY, Ho KL, Chan BD, Luo Y, Zhang JX, Law GL, Tai WCS, Bünzli JCG, Wong KL. A Smart Europium-Ruthenium Complex as Anticancer Prodrug: Controllable Drug Release and Real-Time Monitoring under Different Light Excitations. Journal of Medicinal Chemistry. 2017;60(21):8923-32.
Wong HY, Lo WS, Chan WTK, Law GL. Mechanistic Investigation of Inducing Triboluminescence in Lanthanide(III) β-Diketonate Complexes. Inorganic Chemistry. 2017;56(9):5135-40.
Jiang L, Lan R, Huang T, Chan CF, Li H, Lear S, Zong J, Wong WY, Muk-Lan Lee M, Dow Chan B, Chan WL, Lo WS, Mak NK, Li Lung M, Lok Lung H, Wah Tsao S, Taylor GS, Bian ZX, Tai WCS, Law GL, Wong WT, Cobb SL, Wong KL. EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein-Barr virus. Nature Biomedical Engineering. 2017;1(4).
Dai L, Lo WS, Coates ID, Pal R, Law GL. New Class of Bright and Highly Stable Chiral Cyclen Europium Complexes for Circularly Polarized Luminescence Applications. Inorganic Chemistry. 2016;55(17):9065-70.
Liang Z, Tsoi TH, Chan CF, Dai L, Wu Y, Du G, Zhu L, Lee CS, Wong WT, Law GL, Wong KL. A smart "off-on" gate for the in situ detection of hydrogen sulphide with Cu(ii)-assisted europium emission. Chemical Science. 2016;7(3):2151-6.
Lo WS, Zhang J, Wong WT, Law GL. Highly luminescent Sm<sup>III</sup> complexes with intraligand charge-transfer sensitization and the effect of solvent polarity on their luminescent properties. Inorganic Chemistry. 2015;54(8):3725-7.
Yeung CT, Chan WTK, Yan SC, Yu KL, Yim KH, Wong WT, Law GL. Lanthanide supramolecular helical diastereoselective breaking induced by point chirality: Mixture or P-helix, M-helix. Chemical Communications. 2015;51(3):592-5.
Zhang T, Lan R, Chan CF, Law GL, Wong WK, Wong KL. In vivo selective cancer-tracking gadolinium eradicator as new-generation photodynamic therapy agent. Proceedings of the National Academy of Sciences of the United States of America. 2014;111(51):E5492-E7.




Book Chapters
Organic molecules for optical imaging
MHW Lam, GL Law, CS Lee, KL Wong
The Chemistry of Molecular Imaging, 2014
An introduction to molecular imaging
GL Law, WT Wong
The Chemistry of Molecular Imaging, 1-24, 2014
Multiphoton Processes and Nonlinear Harmonic Generations in Lanthanide Complexes
GL Law
Tomorrow's Chemistry Today: Concepts in Nanoscience, Organic Materials and Environmental Chemistry, 2008