删除或更新信息,请邮件至freekaoyan#163.com(#换成@)

香港浸会大学HongKongBaptistUniversity中医药学院老师简介-禹志领教授

本站小编 Free考研考试/2022-02-04

禹志領教授教學科研部教授;康臣腎病中藥研究中心主任;中藥學碩士學位課程主任
中藥藥理學專家
zlyu@hkbu.edu.hk

禹志領教授本科畢業于河南中醫學院中藥系,後於香港科技大學生物化學系取得哲學博士學位。加入香港浸會大學前,禹教授曾在中國藥科大學、長崎大學、香港科技大學、廈門大學及澳門大學工作。禹教授主要從事中藥藥理及中藥炮製研究。曾發表研究論文200多篇。
康臣藥業集團有限公司及珍卡兒藥妝有限公司,分別與禹教授團隊合作,在浸會大學成立了“康臣腎病中藥研究中心”及“珍卡兒中醫透皮治療實驗室”。
禹志領教授為《時珍國醫國藥》、BMC Complementary Medicine and TherapiesCurrent Topics in Nutraceutical ResearchJournal of Alternative, Complementary & Integrative MedicinePharmacological Research等30多個雜誌的Editorial Board Member/Associate Editor/Executive Editor/ Consulting Editor。
代表性研究課題:
Does atractylenolide I synergize the anti-melanoma effects of MK-8776 by inhibiting cyclin-dependent kinase 2 signaling? GRF, ongoing.
Dose parthenolide overcome vemurafenib resistance by inhibiting heat shock protein 90 in melanoma? GRF, ongoing.
Elucidating the role of TLR4/STAT3 signaling in the antimelanoma effects of atractylenolide II. GRF.
Evaluation of the anti-melanoma action of sesquiterpenes isolated from a traditional Chinese medicinal herb Atractylodis Macrocephalae Rhizoma. GRF.
Regulation of microRNA biogenesis by BRAF/MEK targeted therapy: molecular mechanisms and role in drug resistance. HMRF, ongoing.
Elucidating the involvement of IL-17-IL-6-STAT3 axis in the anti-melanoma effects of a herbal formula comprising Flos Sophorae and Flos Lonicerae. HMRF.
Evaluation of the chronic toxicity of a commonly used Chinese medicinal herb Siegesbeckiae Herba. HMRF.
Research and development of functional foods based on Ganoderma cultivated in Hong Kong. ITF, to be commenced on Sep.1, 2020.
Preclinical study of the category I anti-tumor new drug EN-002 inhibiting the novel targets – DNA replication initiation proteins. ITF.
Research on the Second Development of Yi-Shen-Hua-Shi Granules. ITF.
Study on the pharmacological effects and mechanism of action of Young Yum Pill. ITF.
Study on the Preparation, Safety and Efficacy in Liver Cancer Prevention/Treatment of the Triterpene-enriched Extract from Antrodia Camphorate Mycelia. ITF.
Study on the Processing Standards for Toxic Chinese Materia Medica. ITF.
Standardization of the Vinegar for Processing Chinese Materia Medica. ITF.
Pharmacological Studies for Developing Qian-wang-hong-bai-san as a Modern Therapeutic Agent against Skin Hyperpigmentary Disorders. ITF.
Platform Development for Quality Control Standards of Processed Chinese Materia Medica (Decoction Pieces) in the Hong Kong Market. 3,219,324 HKD (Including Interns and industry support). ITF.
Research and Laboratory Work-Hong Kong Chinese Materia Medica Standards (HKCMMS) Phase VIII. Department of Health.
Research and Laboratory Work-Hong Kong Chinese Materia Medica Standards (HKCMMS) Phase VII. Department of Health.
Establishment of a Research & Development Laboratory for Testing of Chinese Medicines. Hong Kong Jockey Club Charities Trust.
The Role of Noc3p Dimerization in Eukaryotic DNA Replication. HKBU, ongoing.
基於miR-34b/MET/β-catenin 通路探討四君子湯與達卡吧嗪合用抗黑色素瘤的機制. NSFC, ongoing.
基於let-7/IGF1R探索槐花金銀酒抗 黑色素瘤的機制. NSFC, ongoing.
miR-34b在四君子湯抑制黑色素瘤生長中的作用研究. GDNSF.
靶向TLR4信號通路的抗類風濕性關節炎中藥研究. 深圳市學科佈局項目.
基於JNK2信號通路研究豨薟草的長期肺毒性機制. 深圳市自由探索項目, ongoing.
白蘞抗結直腸癌的分子機制研究. 深圳市自由探索項目.
二花營實方的抗炎活性及其分子機制研究. 深圳市自由探索項目.
粵港毒性中藥飲片炮製規範化研究. 廣州市對外科技合作計畫項目.
嶺南中藥材品質標準及標準物質示範性研究.粵港聯合項目.
精選出版物Fu XQ, et al.,Yu ZL*. Activation of STAT3 is a key event in TLR4 signaling-mediated melanoma progression. Cell Death Dis. 2020;11(4):246.
Amin A, et al.,Yu ZL*, Liang C*. An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication. Cell Rep. 2020;30(10):3323-3338.e6.
Chen YJ, et al.,Yu ZL*. A two-herb formula inhibits osteoclastogenesis and suppresses NF-kB and MAPK pathways. J Ethnopharmacol. 2020;252:112625.
Wu JY, et al.,Yu ZL*. Chrysoeriol ameliorates TPA-induced acute skin inflammation in mice and inhibits NF-κB and STAT3 pathways. Phytomedicine. 2020;68:153173.
Su T, et al.,Yu ZL*. The JAK2/STAT3 pathway is involved in the anti-melanoma effects of brevilin A. Life Sci. 2020;241:117169.
Chen YJ, et al.,Yu ZL*. Ribosome-Inactivating Protein α-Momorcharin Derived from Edible Plant Momordica charantia Induces Inflammatory Responses by Activating the NF-kappaB and JNK Pathways. Toxins (Basel). 2019;11(12). pii: E694.
Liu YX, et al.,Yu ZL*. MiR-let-7a/f-CCR7 signaling is involved in the anti-metastatic effects of an herbal formula comprising Sophorae Flos and Lonicerae Japonicae Flos in melanoma. Phytomedicine. 2019;64:153084.
Zhu P, et al.,Yu ZL*. Arnicolide D exerts anti-melanoma effects and inhibits the NF-κB pathway. Phytomedicine. 2019;64:153065.
Zhao J, et al.,Yu ZL*. A patent herbal drug Yi-Shen-Hua-Shi granule ameliorates C-BSA-induced chronic glomerulonephritis and inhabits TGFβ signaling in rats. J Ethnopharmacol. 2019;236:258-262.
Liu JS, et al.,Yu ZL*. Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway. Phytomedicine. 2019;61:152843.
Liu JS, et al.,Yu ZL*. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolides from toad venom. Fitoterapia. 2019;134:362-371.
Liu YX, et al.,Yu ZL*. A TCM formula comprising Sophorae Flos and Lonicerae Japonicae Flos alters compositions of immune cells and molecules of the STAT3 pathway in melanoma microenvironment. Pharmacol Res. 2019;142:115-126.
Chen J, et al.,Yu ZL*. Sea bass (Lateolabrax maculatus) accelerates wound healing: A transition from inflammation to proliferation. J Ethnopharmacol. 2019;236:263-276.
Chen J, et al.,Yu ZL*, Xu B*. Dietary Supplementation with Sea Bass (Lateolabrax maculatus) Ameliorates Ulcerative Colitis and Inflammation in Macrophages through Inhibiting Toll-Like Receptor 4-Linked Pathways. Int J Mol Sci. 2019;20(12). pii: E2907.
Zhu PL, et al.,Yu ZL*. Antrodia camphorata Mycelia Exert Anti-liver Cancer Effects and Inhibit STAT3 Signaling in vitro and in vivo. Front Pharmacol. 2018;9:1449.
Chen L, et al.,Yu ZL*, Cao H, Xiao J*. Intracellular signaling pathways of inflammation modulated by dietary flavonoids: The most recent evidence. Crit Rev Food Sci Nutr. 2018;58(17):2908-2924.
Zhu PL, et al.,Yu ZL*. Schisandra fruits for the management of drug-induced liver injury in China: A review. Phytomedicine. 2019;59:152760.
Tse AKW*, et al.,Yu ZL*. Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKKβ inhibition. Redox Biol. 2017; 11:562-576.
Kwan HY*, et al.,Yu ZL*. The anti-cancer and anti-obesity effects of Mediterranean diet. Crit Rev Food Sci Nutr. 2017; 57(1):82-94.
Cao HH, et al.,Yu ZL*. Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion. Mol Cancer. 2015; 14:103. doi: 10.1186/s12943-015-0367-4.
Kwan HY*, et al.,Yu ZL*. Dietary Lipids and Adipocytes: Potential Therapeutic Targets in Cancers. J Nutr Biochem. 2015; 26:303-11.
Pan SY, et al.,Yu ZL*, Ko KM. New perspectives on dietary-derived treatments and food safety ― Antinomy in a new era. Crit Rev Food Sci Nutr. 2015; 55(13):1836-59.
Tse AW, et al.,Yu ZL*. Indomethacin Sensitizes TRAIL-Resistant Melanoma cells to TRAIL-induced Apoptosis through ROS-mediated Up-regulation of Death Receptor 5 and Down-regulation of Survivin. J Invest Dermatol. 2014; 134:1397-407.
Kwan HY*, et al.,Yu ZL*. Subcutaneous adipocytes promote melanoma cell growth by activating Akt signaling pathway: role of palmitic acid. J Biol Chem. 2014; 289:30525-37.
Cao HH, et al.,Yu ZL*. Quercetin exerts anti-melanoma activities and inhibits STAT3 signaling. Biochem Pharmacol. 2014; 87:424-34.
Tse AK, et al.,Yu ZL*. The Herbal Compound Cryptotanshinone Restores Sensitivity in Cancer Cells that are Resistant to the Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand. J Biol Chem. 2013; 288:29923-33.
Ma XQ, et al.,Yu ZL*. UHPLC UHD Q-TOF MS/MS analysis of the impact of sulfur fumigation on the chemical profile of Codonopsis Radix (Dangshen). Analyst. 2013; 139:505-16.
Kwan HY, et al.,Yu ZL*, Fong WF*. Lipidomics identification of metabolic biomarkers in chemically induced hypertriglyceridemic mice. J Proteome Res. 2013; 12:1387-98.
Tan Y, et al.,Yu ZL*, Zhang W, Lu A. Deciphering the Differential Toxic Responses of Radix aconiti lateralis praeparata in Healthy and Hydrocortisone-Pretreated Rats Based on Serum Metabolic Profiles. J Proteome Res. 2013; 12:513-24.
Kwan HY, et al.,Yu ZL*, Hsiao WL*. The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells. J Gastroenterol. 2013; 48:182-92.
Huo L, et al.,Yu ZL*, Zhai Y, Yang X, Chan TC, Yeung JT, Kan J, Liang C. The Rix1 (Ipi1p-2p-3p) complex is a critical determinant of DNA replication licensing independent of their roles in ribosome biogenesis. Cell Cycle. 2012; 11: 1325-39.
Yu ZL*. Mushroom and Health.Curr Top Nutraceutical Res.2012; 10:V-VI.
Ye Y, et al.,Yu ZL*. Involvement of p38 MAPK signaling pathway in the anti-melanogenic effect of San-bai-tang, a Chinese herbal formula, in B16 cells.J Ethnopharmacol.2010; 132:533-5..
Ye Y, Chou GX*, et al.,Yu ZL*. Screening of Chinese herbal medicines for antityrosinase activity in a cell free system and B16 cells.J Ethnopharmacol.2010; 129:387-90.




相关话题/中医药 香港浸会大学

  • 领限时大额优惠券,享本站正版考研考试资料!
    大额优惠券
    优惠券领取后72小时内有效,10万种最新考研考试考证类电子打印资料任你选。涵盖全国500余所院校考研专业课、200多种职业资格考试、1100多种经典教材,产品类型包含电子书、题库、全套资料以及视频,无论您是考研复习、考证刷题,还是考前冲刺等,不同类型的产品可满足您学习上的不同需求。 ...
    本站小编 Free壹佰分学习网 2022-09-19
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-张敬浩博士
    張敬浩博士教學科研部副教授離子通道、電生理學、上皮轉運和阿爾茨海默氏病專家kingho@hkbu.edu.hk張敬浩博士是本土受訓的生理學家。他於香港理工大學獲得學士學位,並於2004年在香港中文大學從事研究工作並取得生理學博士學位。其後,張博士遠赴美國賓夕法尼亞大學,在Foskett教授的指導下, ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-韩全斌博士
    韓全斌博士吳文政中醫藥副教授;教學科研部副教授天然藥物化學、中藥質量分析及中藥多糖研究專家simonhan@hkbu.edu.hk2003年,韓全斌博士於中科院昆明植物研究所獲得植物化學博士學位。2004-2009年,在香港賽馬會中藥研究院擔任研究員。2009-2011年,在香港中文大學中醫中藥研 ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-张世平博士
    張世平博士教學科研部副教授針灸學及神經科學專家spzhang@hkbu.edu.hk張世平博士1987年畢業於廣州中醫學院,即現在的廣州中醫藥大學。1993年於澳洲悉尼大學獲神經科學方面的博士學位。其後曾於新南威爾士大學生理及藥物學院從事博士後研究,並於1996-1998年執教於悉尼科技大學。199 ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-高加信博士
    高加信博士教學科研部副教授藥理學、毒理學、腫瘤治療及腸胃病專家jksko@hkbu.edu.hk高加信博士於加拿大多倫多大學獲得毒理學及營養科學榮譽學士學位,後於香港大學醫學院從事科研工作,並獲得藥理學博士學位。高博士在港大醫學院任教多年,又積極開展和參與多個研究項目,發表了近百餘篇論文及科學會議摘 ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-锺丽丹博士
    鍾麗丹博士教學科研部助理教授專業研究範圍:中醫及結合醫學治療消化病、婦女疾病、風濕免疫病的臨床研究、中醫及中西醫結合循證醫學及流行病學研究ldzhong@hkbu.edu.hk鍾麗丹博士2002年和2007年畢業於上海中醫藥大學獲醫學學士學位及中醫臨床碩士學位,研究方向為中醫及中西醫結合治療自身免疫 ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-关晓仪博士
    關曉儀博士教學科研部助理教授專注研究營養學,以及肥胖與癌症之間的相互關係。藉以發現新的草本標靶藥物和外泌體療法治療癌症,肥胖及其合併症hykwan@hkbu.edu.hk關博士分別在香港大學取得生物學榮譽理學士,及在香港中文大學醫學院取得生理學哲學博士學位。她在美國加州大學柏克萊分校擔任營養科學博士 ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-刘进博士
    劉進博士教學科研部助理教授liujin@hkbu.edu.hk劉進博士分別於2010年在中山大學取得西醫臨床醫學學士學位,2013年在中山大學取得西醫臨床醫學碩士學位,2016年在香港浸會大學取得生物醫學博士學位。畢業後在香港浸會大學羅守輝骨與關節疾病轉化醫學研究所先後從事博士後研究工作和擔任研究助 ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-王凯亮博士
    王凱亮博士教學科研部助理教授xavierwong@hkbu.edu.hk王凱亮博士分別於2009年和2013年在香港大學獲得生物化學學士學位及博士學位,畢業後曾在香港大學生物醫學學院和香港中文大學從事博士後研究,於2016年加入香港浸會大學中醫藥學院擔任研究助理教授,2020年晉升為助理教授。王博士 ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-蒋明博士
    蔣明博士教學科研部導師mjiang@hkbu.edu.hk蔣明博士於2007年9月來本院任教。來港履新前為南京中醫藥大學教授,從事《金匱要略》為主的中醫課程教學、科研及臨床工作26年。2000年開始主持南京中醫藥大學《金匱要略》教研室工作。該課程於2004年獲選為江蘇省高等學校二類優秀課程。主編的南 ...
    本站小编 Free考研考试 2022-02-04
  • 香港浸会大学HongKongBaptistUniversity中医药学院老师简介-李芳菲博士
    李芳菲博士教學科研部助理教授抗腫瘤藥物研究fangfeili@hkbu.edu.hk李芳菲博士2007年本科畢業于中國海洋大學化學系,同年保送本校碩士研究生。2009年獲得國家留學基金委(CSC)資助赴澳大利亞新南威爾斯大學攻讀博士學位,2013年取得化學博士學位。回國後在中國科學院北京微生物所進行 ...
    本站小编 Free考研考试 2022-02-04