Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 锺尚志教授 (外科学系) |
| 梁承晖教授 (肿瘤学系) |
| 陈志伟教授 (外科学系) |
| Professor James Francis GRIFFITH (影像及介入放射学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1259/bjr.72.859.10624325 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/28WOS source URL
其它资讯
摘要45 patients with squamous cell carcinoma of the oesophagus were examined prior to, and following, pre-operative chemotherapy by spiral CT. Oesophageal CT was performed following gaseous distention of the oesophagus. TNM stage and perceived resectability on CT before and after chemotherapy were compared and related to surgical resectability and pathological staging. T-stage changed in 26% and N-stage changed in 9% of tumours after chemotherapy. Post-chemotherapy CT predicted pathological T-stage with an accuracy of 88% and N-stage with an accuracy of 84%. Six of 14 tumours considered irresectable on CT pre-chemotherapy were considered resectable on post-chemotherapy CT. Five of these six tumours were resectable at surgery. Post-chemotherapy CT predicted surgical resectability with an accuracy of 88%, the main pitfall being underestimation and overestimation of tracheobronchial invasion. CT prediction of chemotherapy response as judged by change in tumour volume was compared with a quantitative pathological assessment of chemotherapy response. 93% of oesophageal tumours changed volume after chemotherapy with 51% having a volume reduction of greater than or equal to 50%. However, no correlation was found between tumour volume reduction on serial CT examinations and either a quantitative pathological assessment of tumour response or patient survival.
着者Griffith JF, Chan ACW, Chow LTC, Leung SF, Lam YH, Liang EY, Chung SCS, Metreweli C
期刊名称British Journal of Radiology
出版年份1999
月份7
日期1
卷号72
期次859
出版社BRITISH INST RADIOLOGY
页次678 - 684
国际标準期刊号0007-1http://aims.cuhk.edu.hk/converis/portal/Publication/285
电子国际标準期刊号1748-880X
语言英式英语
Web of Science 学科类别Radiology, Nuclear Medicine & Medical Imaging; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
