Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 庄立信教授 (肿瘤学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1053/bega.1999.0053 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/3WOS source URL
其它资讯
摘要New imaging techniques offer better ways of measuring response to treatment and remain central to the formal assessment of response in clinical trials and routine clinical practice. Increasing tumour size is consistently associated with progressive disease. However, there is evidence that the designation 'partial response', as determined by conventional imaging techniques, may not always accurately reflect the degree of treatment-induced tumour necrosis. Thus, responses classified as partial on imaging grounds have, in some cases, been shown to be complete pathological responses after surgical resection, implying that residual tumour and necrotic/fibrotic tumour remnants cannot always be accurately distinguished by imaging. In this situation, serological tumour markers such as alphafetoprotein may be useful in measuring the true degree of response. While radiological imaging is likely to remain the main method of assessing response in phase II trials of drugs for the treatment of liver cancer, it may in some instances be useful to apply additional parameters such as alphafetoprotein level.
着者Yang WT, Johnson PJ
期刊名称Best Practice and Research: Clinical Gastroenterology
详细描述Liver Tumours ed. by P.J. Johnson.
出版年份1999
月份12
日期1
卷号1http://aims.cuhk.edu.hk/converis/portal/Publication/3
期次4
出版社BAILLIERE TINDALL
页次6http://aims.cuhk.edu.hk/converis/portal/Publication/37 - 654
国际标準期刊号1521-6918
电子国际标準期刊号15http://aims.cuhk.edu.hk/converis/portal/Publication/32-1916
语言英式英语
关键词hepatocellular carcinoma; imaging techniques; response criteria; tumour markers
Web of Science 学科类别Gastroenterology & Hepatology; GASTROENTEROLOGY & HEPATOLOGY
