Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 庄立信教授 (肿瘤学系) |
| 陈德章教授 (肿瘤学系) |
全文
| 没有全文档案提供 |
引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/19Scopus source URL
其它资讯
摘要In patients with locoregionally advanced nasopharyngeal carcinoma the results of treatment with conventional radiotherapy are unsatisfactory, with significant rates of both distant metastases and local recurrences. The use of neoadjuvant and adjuvant chemotherapy has resulted in consistently high response rates, but no randomized trial has yet demonstrated an improvement in overall survival. Altered-fractionation radiation techniques have not been proven to improve survival in locoregionally advanced nasopharyngeal carcinoma, and extreme caution is required to minimize unpredicted neurological toxicities. An interim analysis of a Head and Neck Intergroup study randomly assigning patients to receive concurrent chemotherapy and radiotherapy and adjuvant chemotherapy or radiotherapy alone has demonstrated significant benefit in overall survival favoring the use of concurrent chemotherapy and radiotherapy. Whether this regimen is applicable to all ethnic and histological groups, however, remains to be proven.
着者Chan A.T.C., Teo P.M.L., Johnson P.J.
期刊名称Current Opinion in Oncology
出版年份http://aims.cuhk.edu.hk/converis/portal/Publication/1998
月份6
日期16
卷号10
期次3
出版社Lippincott Williams & Wilkins Ltd.
出版地United States
页次2http://aims.cuhk.edu.hk/converis/portal/Publication/19 - 225
国际标準期刊号1040-8746
语言英式英语
