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New treatment for hepatocellular carcinoma (1998)_香港中文大学

香港中文大学 辅仁网/2017-06-27

New treatment for hepatocellular carcinoma
Publication in refereed journal


香港中文大学研究人员 ( 现职)
庄立信教授 (肿瘤学系)


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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/0WOS source URL

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摘要Although the incidence of hepatocellular carcinoma (HCC) is likely to start falling in many countries following mass vaccination programmes, large numbers of new cases are likely to be seen for many years to come. For the majority of patients, only palliative treatments can be offered. Systemic chemotherapy does not improve survival. Locoregional therapy is widely used and certainly results in a consistent decrease in tumour size, but clear evidence of any improvement in overall survival remains elusive. We have recently described the application of selective internal radiotherapy using (9http://aims.cuhk.edu.hk/converis/portal/Publication/0)yttrium microspheres. Although response rates by conventional radiological criteria were only modest, several initially inoperable cases became operable and subsequent resection revealed complete pathological remission in some. The resection became possible, not only because of tumour shrinkage, but also because of hypertrophy of the non-tumorous liver. To date, only a small number, probably less than 15% of patients with HCC will be suitable for an attempt at surgical resection and recurrence will occur in more than half of these. We have recently shown that postoperative intra-arterial administration of Lipiodol I-131 may significantly decrease this recurrence rate.

着者Johnson PJ
会议名称Alimentary Disease Week - 9th International Conference on Ulcer Research/4th International conference of Gastroenterology/3rd Asian AGA Course on Gastroenterology
会议开始日12.12.1997
会议完结日17.12.1997
会议地点HONG KONG
期刊名称Journal of Gastroenterology and Hepatology
出版年份1998
月份11
日期1
卷号13
出版社BLACKWELL SCIENCE ASIA
页次S311 - S314
国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/0815-9319
电子国际标準期刊号144http://aims.cuhk.edu.hk/converis/portal/Publication/0-1746
语言英式英语

关键词adjuvant therapy; hepatocellular carcinoma; selective internal radiotherapy
Web of Science 学科类别Gastroenterology & Hepatology; GASTROENTEROLOGY & HEPATOLOGY

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