Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 左中教授 (药剂学院) |
| 林泰宁教授 (药剂学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1002/jcph.96 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/32WOS source URL
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/37Scopus source URL
其它资讯
摘要Radix Puerariae has been traditionally used for the treatment of diarrhea, acute dysentery, deafness and cardiovascular diseases. Yege (Gegen or Radix Puerariae lobatae), the dried root of Pueraria lobata (Wild.) Ohwi, has been widely used in China and, to a lesser extent, in Japan, Korea, and the United States. Although they have been classified into different categories in Chinese Pharmacopoeia, Yege is often used interchangeably in practice with Fenge (Radix Puerariae thomsonii), which is the dried root of Pueraria thomsonii Benth. Among various commercially available products of Radix Puerariae, injection of puerarin, the major isoflavone from Radix Puerariae, has been most widely used as a vasodilator for the treatment of angina and myocardial infarction. Considering the extensive clinical usage and recent alert of fatal herb-drug interaction of Radix Puerariae, the current review is proposed to cover its traditional applications, pharmacological activities, pharmacokinetics, clinical efficacy, and potential herb-drug interactions aiming to fill in the information gaps of this herb for frontline practitioners. Although various small, poorly designed clinical trials have demonstrated the safety, efficacy, and significant clinical benefits of Radix Puerariae, prospective randomized controlled clinical trials are needed to further establish its effective and safe use. ? The Author(s) 2013.
着者Zhang Z., Lam T.-N., Zuo Z.
期刊名称Journal of Clinical Pharmacology
出版年份2013
月份8
日期1
卷号53
期次8
出版社SAGE Publications
出版地United States
页次787 - 811
国际标準期刊号0091-2700
电子国际标準期刊号1552-4604
语言英式英语
关键词Cardiovascular diseases, Pueraria lobata, Puerarin, Radix puerariae, Traditional chinese medicine
