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In silico studies of energy metabolism of normal and diseased heart (2000)_香港中文大学

香港中文大学 辅仁网/2017-06-25

In silico studies of energy metabolism of normal and diseased heart
Publication in refereed journal


香港中文大学研究人员 ( 现职)
李卓予教授 (生物医学学院)
韦妙宜教授 (那打素护理学院)
冯国培教授 (生物医学学院)
徐国荣教授 (生物医学学院)
倪世明教授 (生命科学学院)


全文


引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/2WOS source URL

其它资讯

摘要Biotechnology research is developing into genomic analyses that involve the simultaneous monitoring of thousands of genes. The development of various bioinformatics resources that provide efficient access to information is necessary. We have used single-pass sequencing of randomly selected cDNA clones to generate expressed sequence tags (ESTs). These ESTs data has been widely used to study gene expression in a variety of heart libraries [1, http://aims.cuhk.edu.hk/converis/portal/Publication/2]. Data annotation on our recent finding allows us to construct the profiles of genes in the energy metabolizing pathways (glycolysis and glycogen metabolism) that are expressed in heart cDNA libraries. In silico studies of genes of energy metabolism yields data that are consistent with results derived from conventional metabolic experiments. The change in gene profiles describing the metabolism of diseased hearts is also presented here.

着者Ngai SM, Way MMY, Chan H, Tsui SKW, Lee CY, Fung KP
期刊名称Molecular Biology Reports
出版年份http://aims.cuhk.edu.hk/converis/portal/Publication/2000
月份6
日期1
卷号http://aims.cuhk.edu.hk/converis/portal/Publication/27
期次http://aims.cuhk.edu.hk/converis/portal/Publication/2
出版社KLUWER ACADEMIC PUBL
页次1http://aims.cuhk.edu.hk/converis/portal/Publication/23 - 1http://aims.cuhk.edu.hk/converis/portal/Publication/28
国际标準期刊号0301-4851
电子国际标準期刊号1573-4978
语言英式英语

关键词energy metabolism; ESTs; heart; in silico
Web of Science 学科类别Biochemistry & Molecular Biology; BIOCHEMISTRY & MOLECULAR BIOLOGY

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