Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 霍泰辉教授 (儿科学系) |
| 宋银子教授 (医学院) |
| 李民瞻教授 (儿科学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1080/02770900500497990 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/3WOS source URL
其它资讯
摘要Children with stable asthma receiving twice-daily fluticasone propionate (FP) were studied. Spirometry, exhaled nitric oxide (eNO) and sputum eosinophils were measured at baseline and 8 weeks after FP was changed to once-daily use while keeping the same total dosage. Visual analogue scores on asthma severity, symptoms, and dosing regimen preference were obtained. Twenty-nine children of mean age 10.6 years (SD 2.5) were recruited. There was significant improvement in eNO (47.1 ppb [http://aims.cuhk.edu.hk/converis/portal/Publication/30.http://aims.cuhk.edu.hk/converis/portal/Publication/3] vs. http://aims.cuhk.edu.hk/converis/portal/Publication/39.9 ppb [27.1], p = 0.0http://aims.cuhk.edu.hk/converis/portal/Publication/37), and sputum eosinophils (5.7% [6.5] vs. 2.5% [http://aims.cuhk.edu.hk/converis/portal/Publication/3.9], p = 0.024] after 8 weeks. All subjects preferred the once-daily dosing regimen. Once-daily FP is effective in controlling airway inflammation. This frequency of medication use is also the preferred regimen.
着者Li AM, Tsang TWT, Chan K, Chan DFY, Sung RYT, Fok TF
期刊名称JOURNAL OF ASTHMA
出版年份2006
月份1
日期1
卷号4http://aims.cuhk.edu.hk/converis/portal/Publication/3
期次2
出版社TAYLOR & FRANCIS INC
页次107 - 111
国际标準期刊号0277-090http://aims.cuhk.edu.hk/converis/portal/Publication/3
语言英式英语
关键词airway inflammation; asthma; fluticasone propionate; once-daily
Web of Science 学科类别Allergy; ALLERGY; Respiratory System; RESPIRATORY SYSTEM
