Sputum induction in children with asthma: A tertiary-center experience
Publication in refereed journal


香港中文大学研究人员 ( 现职)

霍泰辉教授 (儿科学系)

宋银子教授 (医学院)

苏鸿钧博士 (儿科学系)

林鸿生教授 (儿科学系)

李民瞻教授 (儿科学系)

全文

数位物件识别号 (DOI) http://dx.doi.org/10.1002/ppul.20371

引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/5WOS source URL

其它资讯

摘要Our aims were 1) to report on our experience with sputum induction (Sl), and 2) to determine predictive factors associated with successful Sl in asthmatic children. Children with asthma attending the chest clinic of a university teaching hospital between October 2003-December 2004 were recruited. They completed a visual analogue scale for symptom severity, and underwent physical examination, skin-prick test, exhaled nitric oxide (eNO) measurement, spirometry, and SI. Adequate sputum contained 80%). The median eNO was 48.9http://aims.cuhk.edu.hk/converis/portal/Publication/5 ppb. Sputum induction was successful in 93 subjects (74.http://aims.cuhk.edu.hk/converis/portal/Publication/5%). Sore throat and chest discomfort occurred in 20 (1http://aims.cuhk.edu.hk/converis/portal/Publication/5%) and 8 (6%) subjects, respectively, and the procedure was prematurely terminated in three cases. Levels of eNO were found to be a predictor for successful induction (area under the ROC (receiver operator characteristics curves) curve, 0.634). Sputum induction was well-tolerated by all subjects, and was successful in 74.http://aims.cuhk.edu.hk/converis/portal/Publication/5% of cases. Exhaled nitric oxide may be a useful marker for successful induction.

着者Li AM, Tsang TWT, Chan DFY, Lam HS, So HK, Sung RYT, Fok TF
期刊名称PEDIATRIC PULMONOLOGY
出版年份2006
月份8
日期1
卷号41
期次8
出版社WILEY-LISS
页次720 - 72http://aims.cuhk.edu.hk/converis/portal/Publication/5
国际标準期刊号87http://aims.cuhk.edu.hk/converis/portal/Publication/5http://aims.cuhk.edu.hk/converis/portal/Publication/5-6863
电子国际标準期刊号1099-0496
语言英式英语

关键词asthma; child; exhaled nitric oxide; sputum
Web of Science 学科类别Pediatrics; PEDIATRICS; Respiratory System; RESPIRATORY SYSTEM