Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 苏乐仪教授 (儿科学系) |
| 宋银子教授 (医学院) |
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| 没有全文档案提供 |
引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/31Scopus source URL
其它资讯
摘要Objective. To describe the epidemiology, clinical characteristics, and management of Kawasaki disease in children in Hong Kong. Design. Retrospective survey of medical records from July 1994 to June 1997, and prospective data collection from July 1997 to June 2000. Setting. Hospitals with a paediatric unit in Hong Kong. Patients. Patients diagnosed with Kawasaki disease between July 1994 and June 2000 in public hospitals in Hong Kong. Main outcome measures. Incidence of Kawasaki disease and coronary artery aneurysm rates. Results. A total of 696 cases of Kawasaki disease were reported. There were 435 (62.5%) boys and 261 (37.5%) girls giving a male to female ratio of 1.7:1. The age ranged from 1 month to 15 years 5 months with a median of 1.7 years. Infants (<1 year) constituted the largest group of patients (223, 32.0%) and overall, 638 (91.7%) were younger than 5 years. Skin rash, conjunctivitis, and oral signs were among the principal clinical features present in over 80% of cases. Prominent cervical lymph nodes larger than 1.5 cm were less commonly found (24%). Coronary artery aneurysms or ectasia were present in 15.7% (109/696), 8.5% (59/696), and 5.0% (35/696) of patients at 2,4, and 8 weeks, respectively. The incidence of Kawasaki disease per 100 000 children under 5 years was significantly higher in the prospective study period than in the retrospective period (39 vs 26, P<0.001). Conclusion. The incidence of Kawasaki disease is high in Hong Kong and is 39 per 100 000 children below 5 years of age. The coronary artery aneurysm prevalence is 5%. Intravenous gamma-globulin and high-dose aspirin is the mainstay of treatment.
着者Ng Y.M., Sung R.Y.T., So L.Y., Fong N.C., Ho M.H.K., Cheng Y.W., Lee S.H., Mak W.C., Wong D.M.L., Yam M.C., Kwok K.L., Chiu W.K.
期刊名称Hong Kong Medical Journal
出版年份2005
月份10
日期1
卷号11
期次5
出版社Hong Kong Academy of Medicine Press
出版地Hong Kong
页次3http://aims.cuhk.edu.hk/converis/portal/Publication/31 - 335
国际标準期刊号1024-2708
电子国际标準期刊号2226-8707
语言英式英语
关键词Child, Coronary aneurysms, Incidence, Mucocutaneous lymph node syndrome
