Publication in refereed journal
香港中文大学研究人员 ( 现职)
霍泰辉教授 (儿科学系) |
宋银子教授 (医学院) |
李民瞻教授 (儿科学系) |
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Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/2Scopus source URL
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摘要Asthma is characterised by variable degrees of airway obstruction, airway hyper-responsiveness, and chronic airway inflammation. Current guidelines emphasise that inhaled corticosteroid treatment is the mainstay of asthma therapy because it targets the underlying airway inflammation. It is prudent to use the lowest possible dose of inhaled corticosteroid compatible with good asthma control. In clinical practice, the use of or the reduction of inhaled corticosteroid dosage is based on symptoms and lung function, both of which have been shown to have a poor correlation with airway inflammation. The use of induced sputum as a marker of airway inflammation improves asthma monitoring and optimises treatment in adults. This review discusses the technique of sputum induction, its clinical application, and our experience of its use in asthmatic children.
着者Li A.M., Tsang T.W.T., Chan D.F.Y., Sung R.Y.T., Fok T.F.
期刊名称Hong Kong Medical Journal
出版年份http://aims.cuhk.edu.hk/converis/portal/Publication/2005
月份8
日期1
卷号11
期次4
出版社Hong Kong Academy of Medicine Press
出版地Hong Kong
页次http://aims.cuhk.edu.hk/converis/portal/Publication/289 - http://aims.cuhk.edu.hk/converis/portal/Publication/294
国际标準期刊号10http://aims.cuhk.edu.hk/converis/portal/Publication/24-http://aims.cuhk.edu.hk/converis/portal/Publication/2708
电子国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/2http://aims.cuhk.edu.hk/converis/portal/Publication/2http://aims.cuhk.edu.hk/converis/portal/Publication/26-8707
语言英式英语
关键词Asthma, Child, Eosinophils, Sputum