Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 卢煜明教授 (化学病理学系) |
| 赵慧君教授 (化学病理学系) |
全文
| 没有全文档案提供 |
引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/7Scopus source URL
其它资讯
摘要Prenatal diagnosis has become a standard part of obstetrics care. Genetic diagnoses are established prenatally through the sampling of fetal genetic material by invasive methods such as amniocentesis or chorionic villus sampling, which are associated with a risk of fetal loss. Hence, the recent discovery of the presence of fetal DNA in maternal plasma has led to exciting possibilities of noninvasive prenatal diagnosis. Numerous applications have since been reported for the analysis of circulating fetal DNA. The accuracy of fetal DNA assessment from maternal plasma is dependent on the appropriate preanalytical handling of maternal blood samples, an efficient fetal DNA extraction protocol, and a sensitive and specific detection method. The protocol that has been applied regularly in the laboratory of the authors for the reliable detection and quantification of circulating fetal DNA is presented in this chapter.
着者Chiu R.W., Lo Y.M.
期刊名称Methods in Molecular Biology
详细描述ed. by YMD Lo, RWK Chiu and KCA Chan..
出版年份2006
月份10
日期3
卷号336
出版社Humana Press, Inc.
出版地United States
页次101 - 109
国际标準期刊号1064-3http://aims.cuhk.edu.hk/converis/portal/Publication/745
语言英式英语
