Publication in policy or professional journal
香港中文大学研究人员 ( 现职)
| 庄立信教授 (肿瘤学系) |
| 赵慧君教授 (化学病理学系) |
| 卢煜明教授 (化学病理学系) |
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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/49WOS source URL
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摘要The recent interest in nucleic acids in plasma and serum has opened up numerous new areas of investigation and new possibilities for molecular diagnosis. In oncology, tumor-derived genetic changes, epigenetic alterations, and viral nucleic acids have been found in the plasma/serum of cancer patients. These findings have important implications for the detection, monitoring, and prognostication of many types of malignancies. In prenatal diagnosis, the discovery of fetal DNA in maternal plasma and serum has provided a noninvasive source of fetal genetic material for analysis. This development has important implications for the realization of noninvasive prenatal diagnosis and has provided new methods for the monitoring of pregnancy-associated disorders. Plasma DNA technology has also found recent applications in the fields of organ transplantation, posttrauma monitoring, and infectious agent detection. Future areas of study include circulating RNA in plasma and the elucidation of the biology of release, clearance, and possible functionality of plasma nucleic acids.
着者Lo YMD
会议名称2nd International Symposium on Circulating Nucleic Acids in Plasma or Serum held in conjunction with the 6th Annual Scientific Symposium of the Hong-Kong-Cancer-Institute
会议开始日20.02.2001
会议完结日21.02.2001
会议地点HONG KONG
期刊名称Annals of the New York Academy of Sciences
出版年份2001
月份1
日期1
卷号945
出版社NEW YORK ACAD SCIENCES
国际标準书号1-57331-378-5
国际标準期刊号0077-8923
电子国际标準期刊号17http://aims.cuhk.edu.hk/converis/portal/Publication/49-6632
语言英式英语
关键词cancer detection; circulating RNA; noninvasive prenatal diagnosis; organ transplantation; overview; plasma DNA
Web of Science 学科类别Biochemistry & Molecular Biology; Multidisciplinary Sciences; Science & Technology - Other Topics
