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广西南宁市大学东路100号广西大学亚热带国家重点实验室
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曾杨娉
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动物科学技术学院
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2018年7月至今，广西大学, 亚热带农业生物资源保护与利用国家重点实验室, 助理教授教育背景2014年 09月 -2018年 06月西北农林科技大学，动物科技学院，动物遗传育种与繁殖专业，博士阶段（导师：陈宏 教授）2011年 09月-2014年 06月西北农林科技大学，动物科技学院，动物遗传育种与繁殖专业，硕士阶段（导师：郑惠玲 教授）2007年 09月 -2011年 06月河南农业大学，牧医工程学院，动物科学专业，攻读学士学位
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Journal of Cellular Physiology、Molecular Therapy-Nucleic Acids, Scientific Reports、GENE等杂志审稿人
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生物统计附实验设计（本科）动物的生长与发育（博士）畜牧科学研究进展（博士）
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2011年至今，一直从事牛羊遗传育种的研究工作，研究方向聚焦于：①动物表观遗传/转录调控：肌肉发育表观遗传/转录调控机制（包括非编码RNA）；②动物遗传资源与生物技术育种研究与应用：优异性状基因资源挖掘、开发与利用；③动物生物信息分析：基于高通量测序的动物组学大数据挖掘。
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主持/参与项目1. 广西大学-助理教授科研启动经费，2018/09/01-2020/12/31，主持，30万。2. 广西自然科学基金面上项目，2018JJA130254，水牛成肌细胞增殖分化关键候选环状RNA的筛选及其调控机制研究，2019/03/01-2022/02/28，主持，12万。3. 国家自然科学基金面上项目，**，环状RNA circMDs调控牛肌细胞增殖分化的机制研究，2018/01-2021/12，61万，参加。4. 国家自然科学基金面上项目，**，牛脂肪细胞增殖分化过程中关键候选lncRNA BADLNRs的功能及其调控机制研究，2017/01-2020/12，62万，参加。
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学术成果在Molecular Therapy-Nucleic Acids, Cell Death ＆ Disease, Journal of Animal Science, Journal of Cellular Physiology等 SCI 期刊已发表论文16篇；其中以第一作者（含并列第一）发表论文 13 篇，合计影响因子超过50。以第一作者发表的文章：1.Li H, Yang J, Jiang R, Wei X, Dong D, Huang Y, Lan X, Plath M, Lei C, Lin F, Bai Y, Chen H*: Long non-coding RNA profiling reveals an abundant lncRNA MDNCR that regulates myoblasts differentiation and survival by sponging miR-133a. Molecular Therapy-Nucleic Acids, 2018, 12 :610-625 (IF:6.392, JCR一区, 中科院二区)2.Li H, Wei X, Yang J, Dong D, Hao D, Huang Y, Lan X, Plath M, Lei C, Lin F, Bai Y, Chen H*: circFGFR4 promotes differentiation of myoblasts via binding miR-107 to relieve inhibition of Wnt3a. Molecular Therapy-Nucleic Acids, 2018, 11: 272-283 (IF: 6.392, JCR一区, 中科院二区)3.Li H, Yang J, Wei X, Song C, Dong D, Huang Y, Lan X, Martin Plath, Lei C, Qi X, Bai Y, Chen H*: circFUT10 reduces proliferation and facilitates differentiation of myoblasts by sponging miR-133a. Journal of Cellular Physiology, 2018, 233(6):4643-4651 (IF: 4.08, JCR一区, 中科院二区)4.Li H, Wei X, Yang J, Dong D, Huang Y, Lan X, ... ＆ Chen H*. (2017). Developmental transcriptome profiling of bovine muscle tissue reveals an abundant GosB that regulates myoblast proliferation and apoptosis. Oncotarget, 2017, 8(19):32083 (IF=5.168, JCR一区, 中科院二区)5.Li H, Zheng H*, Li L., Shen X., Zang W., ＆ Sun Y. (2016). The Effects of Matrix Metalloproteinase-9 on Dairy Goat Mastitis and Cell Survival of Goat Mammary Epithelial Cells. PloS one, 11(8), e**. ( IF=3.057，JCR一区，中科院三区)6.Li H, Li L, Zheng H*, Yao X, Zang W: Regulatory effects of ΔFosB on proliferation and apoptosis of MCF-7 breast cancer cells. Tumor Biology 2015:1-11.( IF=3.65，JCR二区，中科院二区)7.Li H, Zheng H*, Sun Y, Yu Q, Li L: Signal transducer and activator of transcription 5a inhibited by pimozide may regulate survival of goat mammary gland epithelial cells by regulating parathyroid hormone-related protein. Gene 2014;551:279-289. ( IF=2.415，JCR、中科院三区)8.Li H, Sun Y, Zheng H*, Li L, Yu Q, Yao X: Parathyroid hormone-related protein overexpression protects goat mammary gland epithelial cells from calcium-sensing receptor activation-induced apoptosis. Molecular Biology Reports 2015;42:233-243. ( IF=2.024，JCR、中科院四区)9.Li H, Yao X, Li L, ＆ Zheng H* (2016). The Role of ΔFosB on the Pro-survival Effect of PTHrP in Goat Mammary Epithelial Cells. Applied Biochemistry and Biotechnology, 180(4), 707-716. (IF=1.751，JCR、中科院三区)以并列第一作者发表的文章：10.Shujun Peng, Chengchuang Song, Hui Li, Xiukai Cao, Yilei Ma, Xiaogang Wang,Yongzhen Huang, Xianyong Lan, Chuzhao Lei, Hong Chen*, Circular RNA SNX29 sponges miR-744 to inhibit proliferation and promote differentiation of myoblasts by activating the Wnt5a/Ca2+ signaling pathway. Molecular Therapy-Nucleic Acids, 2019, (并列第一, IF:5.66, JCR一区, 中科院二区)11.Zang WJ, Li H, Zhang ZF, Zheng H*, Zhang D, J. J. Loor: Serotonin induces parathyroid hormone-related protein in goat mammary gland. Journal of Animal Science (DOI: 10.1093/jas/skx023; 并列第一, IF=1.863，JCR一区，中科院一区Top期刊) 12.Wei XF, Li Hui, Yang Jiameng, Hao Dan, Dong Dong, Huang Yongzhen, Lan Xianyong, Martin Plath, Lei Chuzhao, Lin Fengpeng, Bai Yueyu, and Chen Hong*: Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p. Cell Death ＆ Disease 2017, 8: e3153 (并列第一, IF=5.965，JCR一区，中科院二区) 13.Wei XF, Li H, Zhao GW, Yang J, Li Lihui, Dong D, Song C, Huang Y, Lan X, Martin Plath, Lei C, Qi X, Bai Y, Chen H*: ΔFosB regulates rosiglitazone-induced milk fat synthesis and cell survival. Journal of Cellular Physiology. IF: 4.08 (DOI:10.1002/jcp.26218; 并列第一, JCR一区, 中科院二区)参与发表的文章14.Zheng H*, Li H, Li L, Ma S, Liu X: ΔFosB regulates Ca2+ release and proliferation of goat mammary epithelial cells. Gene 2014;545:241-246. (中科院三区，IF=2.415)15.Zheng H*, Li H, Sun Y, Yang Z, Yu Q: Parathyroid hormone-related peptide (PTHrP): Prokaryotic expression, purification, and preparation of a polyclonal antibody. Genet Mol Res 2014;13:6448-6454. (IF=0.775, JCR、中科院四区)16.Wei X, Li H, Zhang B, Li C, Dong D, Lan X, ... ＆ Chen H* (2016). miR-378a-3p promotes differentiation and inhibits proliferation of myoblasts by targeting HDAC4 in skeletal muscle development. RNA Biology, 13(12), 1300-1309. ( IF=4.076, JCR、中科院二区)
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