董传甫
Submitted on 周一, 10/30/2017 - 20:54
性别
男
电子邮件
dongchfu@mail.sysu.edu.cn
职称
副教授
导师类型
博士生导师
学历
博士
学科方向
0710生物学-04水生生物学
研究方向
?水生经济动物病毒性病害---病原生物学、疫苗学与免疫生物学???
学术成就
? ?早期主要从事水生经济动物细菌性病害的研究,包括大宗淡水鱼常见细菌病和海水养殖鱼类弧菌病,在国内首先分离、鉴定并保种极高毒力鳗鲡创伤弧菌(生物1型)。
? ? ? 2005年—至今主要从事水生经济动物病毒性病害的病原生物、免疫和疫苗方面的研究工作。主持国家自然科学基金青年、面上,973子课题、博士后基金面上(一等)、博士后特别基金,教育部中央高校基金、中山大学应用性科技成果转化基金及广东渔业科技专项等多个项目,参与多项国家级、省级重点研发项目。在虹彩病毒、疱疹病毒等水生病毒研究领域做出原创性学术贡献。以第一作者或通讯作者在JVI,Virology,Virus Res,Vet Microbiol,Fish & shellfish Immunol及DCI等病毒学/兽医科学/水产学等领域的国际专业期刊发表研究论文20余篇。作为核心成员参与研制的《鳜传染性脾肾坏死病灭活疫苗(NH0618株)》获国家农业农村一类新兽药注册证书【(中华人民共和国农业农村部公告 第253号,(2019)新兽药证字75号)】。
论文专著
(一)、研究论文
Selected Peer-reviewed Published Articles (* or**, corresponding author):
27. Sun Y, Zhu Z, Weng S, He J and Dong C*. 2020. Characterization of a highly lethal barramundi (Lates calcarifer) model of Pseudomonas plecoglossicida infection. Microbial Pathogenesis, 149 (2020), 104516.
26 Zhu Zhiming, Duan Chao, Dong C*, Weng Shaoping and He Jianguo*. 2020. Epidemiological situation and phylogenetic relationship of Vibrio harveyi in marine-cultured fishes in China and Southeast Asia. Aquaculture, 529 (2020) 735652.
25. Zhang W, Duan C, Weng S, He J and Dong C*. 2020. Widespread outbreaks of the emerging mandarin?sh ranavirus (MRV) both in natural and ISKNV-FKC vaccinated mandarin?sh Siniperca chuatsi in Guangdong, South China, 2017. Aquaculture, 520 (2020) 734989.
24. Zhu Z, Dong C*., Weng S., He J*. 2019. Identification of outer membrane protein TolC as the major adhesin and potential vaccine candidate for Vibrio harveyi in hybrid grouper, Epinephelus fuscoguttatus (♀) × E. lanceolatus (♂). Fish Shellfish Immunol.?86:143-151.
23. Gao Y, Suárez Nicolás M., Wilkie Gavin S., Dong C,?Bergmann Sven, Lee Pei Yu Alison, Davison Andrew J., Vanderplasschen Alain F. C.* and Boutier Maxime. 2018. Genomic and biologic comparisons of cyprinid herpesvirus 3 strains. Vet Res (2018) 49:40.
22. Zhu Z, Dong C*, Weng S and He J*. 2018. The high prevalence of pathogenic Vibrio harveyi with multiple antibiotic resistance in scale drop and muscle necrosis disease of the hybrid grouper, Epinephelus fuscoguttatus (♀) × E. lanceolatus (♂), in China. J Fish Dis.?41(4):589-601.
21. Dong C*, Wang Z, Weng S and He J 2017. Occurrence of a lethal ranavirus in hybrid mandarin (Siniperca scherzeri × Siniperca chuatsi) in Guangdong, South China. Vet microbiol,203,28-33.
20. Lee X, Weng S, Zhang H, Zeng J, He J* and Dong C* 2016. Identification and expression analysis of cellular and viral microRNAs in CyHV3-infected KCF-1 cells. Gene, 592(1):154-63.
19. Qi H, Yi Y, Weng S, Zou W, He J* and Dong C*., 2016. Differential autophagic effects triggered by five different vertebrate iridoviruses in a common, highly permissive mandarinfish fry (MFF-1) cell model. Fish Shellfish Immunol.49, 407-419.
18. Lee X, Yi Y, Weng S, Zeng J, Zhang H, He J* and Dong C*., 2016. Transcriptomic analysis of koi (Cyprinus carpio) spleen tissue upon cyprinid herpesvirus 3 (CyHV3) infection using next generation sequencing. Fish Shellfish Immunol. 49, 213-224.
17. Yi, Y., Qi, H., Yuan, J., Wang, R., Weng, S., He, J., Dong, C*., 2015. Functional characterization of viral tumor necrosis factor receptors encoded by cyprinid herpesvirus 3 (CyHV3) genome. Fish Shellfish Immunol. 45 (2), 757-770.
16. Li, W., Lee, X., Weng, S., He, J*., Dong, C*. 2015. Whole-genome sequence of a novel Chinese cyprinid herpesvirus 3 isolate reveals the existence of a distinct European genotype in East Asia. Vet microbiol, 175, 185-194.
15. Dong C*, Shuang F, Weng S and He J. 2014. Cloning of a new fibroblast cell line from an early primary culture from mandarin fish (Siniperca chuatsi) fry for efficient proliferation of megalocytiviruses. Cytotechnology, 66:883–890.
14. Yi Y, Zhang H, Lee X, Weng S, He J and Dong C*. 2014. Extracellular virion proteins of two Chinese CyHV-3/KHV isolates, and identification of two novel envelope proteins. Virus Res 191, 108-116.
13. Xiang Z, Weng S, Qi H, He J and Dong C*. 2014. Identification and characterization of a novel FstK-like protein from spotted knifejaw iridovirus (genus Megalocytivirus). Gene, 545, 233-240.
12. Li, W., Zhang, X., Weng, S., Zhao, G., He, J., Dong, C*. 2014. Virion-associated viral proteins of a Chinese giant salamander (Andrias davidianus) iridovirus (genus Ranavirus) and functional study of the major capsid protein (MCP). Vet Microbiol, 172, 129-139.
11. Dong C*, Li X, Weng S, Xie S and He J*. 2013. Emergence of fatal European genotype CyHV-3/KHV in mainland China. Vet microbiol, 162(1):239-44.?
10. Shuang F, Luo Y, Xiong X, Weng S, Li Y, He J*, and Dong C**. 2013. Virion proteins of an RSIV type megalocytivirus from spotted knifejaw Oplegnathus punctatus (SKIV-ZJ07). Virology, 437(2): 89-99.?
9. Dong C, Xiong X, Luo Y, Weng S, Wang Q and He J*.?2013. Efficacy of a formalin-killed cell vaccine against infectious spleen and kidney necrosis virus (ISKNV) and immunoproteomic analysis of its major immunogenic proteins. Vet microbiol, 162(2-4): 419-428. ??
8. Dong, Y., Weng, S., He, J., Dong, C*. 2013. Field trial tests of FKC vaccines against RSIV genotype Megalocytivirus in cage-cultured mandarin fish (Siniperca chuatsi) in an inland reservoir. Fish Shellfish Immuno, l 35, 1598-1603.
7. Dong C, Weng S, Li W, Li X, Yi Y, Liang Q, He J*. 2011. Characterization of a new cell line from caudal fin of koi, Cyprinus carpio koi, and first isolation of cyprinid herpesvirus
6. Dong C, Xiong X, Shuang F, Weng S, Zhang J, Zhang Y, Luo Y, He J*. 2011. Global landscape of structural proteins of infectious spleen and kidney necrosis virus. J Virol,;85(6):2869-77. ?
5. Xiang Z, Dong C (Co-first authors), Qi L, Chen W, Huang L, Li Z, Xia Q, Liu D, Huang M, Weng S, He J*. 2010. Characteristics of the interferon regulatory factor pairs zfIRF5/7 and their stimulation expression by ISKNV Infection in zebrafish (Danio rerio). Dev Comp Immunol, 34(12):1263-73.
4. Xiong X, Dong C, Weng S, Zhang J, Zhang Y, He J*. 2011. Antigenic identification of virion structural proteins from infectious spleen and kidney necrosis virus. Fish Shellfish Immunol, 31(6):919-24.?
3. Xiong X, Dong C, Xu X, Weng S, Liu Z, He J*. 2011. Proteomic analysis of zebrafish (Danio rerio) infected with infectious spleen and kidney necrosis virus. Dev Comp Immunol, 35(4):431-40.
2. Dong C, Weng S, Luo Y, Huang M, Ai H, Yin Z, He J*. 2010. A new marine megalocytivirus from spotted knifejaw, Oplegnathus punctatus, and its pathogenicity to freshwater mandarinfish, Siniperca chuatsi. Virus Res, 147(1):98-106. ?
1. Dong C, Weng S, Shi X, Xu X, Shi N, He J*. 2008. Development of a mandarin fish Siniperca chuatsi fry cell line suitable for the study of infectious spleen and kidney necrosis virus (ISKNV). Virus Res, 135(2):273-81.
(二)、发明专利或生物制品
1,发明专利:何建国,董传甫,殷志新,翁少萍。传染性脾肾坏病毒疫苗及其制备方法和应用,专利号:ZL2.8。授权时间,2012.2。
2,新兽药注册证书(一类):《鳜传染性脾肾坏死病灭活疫苗(NH0618株)》,国家农业农村部一类新兽药证书【(中华人民共和国农业农村部公告 第253号,(2019)新兽药证字75号)】,2019年12月30日。
(三)、国际学术会议:
1,Dong C *, Shuang F, Weng S, He J. Virion proteins of an RSIV type megalocytivirus from spotted knifejaw Oplegnathus punctatus (SKIV-ZJ07). XIX Poxvirus, Asfarvirus and Iridovirus conference. Salamanca in Spain, 25-29 June 2012. Presentation as a POSTER.
2,Dong C * and He J, A mini-review on fish iridovirus and iridoviral diseases: emphasis on Megalocytivirus. Asian Aquaculture Conference, 3-6 December, 2018, AIT BANKOK, THAILAND.